Theorical aspects in measurement of impacts on social environment of special wastes

La gestión de los residuos tóxicos y\ud peligrosos es uno de los objetivos prioritarios en los países desarrollados. Los planes elaborados para ello deben considerar tanto el posible impacto\ud ambiental que provocan las instalaciones de tratamiento como el posible efecto sobre el medio social. El objetivo de este trabajo es la discusión conceptual de los efectos de los centros de gestión de residuos en el medio social y la selección de los\ud indicadores apropiados a partir de la encuesta directa a expenos y AdministraciónThe management of toxic an dangerous waste is one of the main goal of the development countries. The plans elaborated by those countries must consider, the posible environmental impact\ud that produce the treatment facilities and the effect\ud upon the social environment. The objetive of this work is the discussion of the effects of the management waste centers upon the social environment\ud and the selection of the appropiate variables based\ud on direct questionaries to experts and administrations

Alojamientos rurales en España: entre el crecimiento acelerado y el peligro de una sobredimensión

El turismo en espacios rurales y naturales en España se consolida a partir de 1995, como muestra la tendencia general al crecimiento de los alojamientos realizados en estas áreas. Estos se localizan especialmente en zonas de montaña, en lugares con paisajes agrarios sobresalientes y donde se concentra una significativa parte de recursos culturales. En el momento actual la oferta puede que esté sobredimensionada en relación a los principales demandantes que son los turistas españoles.Since 1995 tourism in natural and rural areas in Spain is consolidated, as it is demonstrated by growing trends in accommodation facilities opened in these areas. These facilities are mainly located in mountainous areas, in areas possessing outstanding agrarian landscapes and in those concentrating a significant share of cultural resources. Currently, it may be the case that the supply in accommodation facilities is over-dimensioned with respect to the main group of demanders; the Spanish tourists

Historia del Cuerpo Nacional de Policía

El trabajo presentado abarca desde los primeros antecedentes del CNP hasta su configuración actual, viendo de esta manera su primera aparición, sus modificaciones más significativas y su adecuación a las demandas sociales de cada momento histórico. Finalmente conoceremos su régimen jurídico actual, su naturaleza y su funciones más relevantes.<br /

La Comunidad de Madrid : un turismo emergente en sus territorios rurales y naturales

En los territorios rurales de la Comunidad de Madrid se ha consolidado en los últimos lustros una notable función turística. En los últimos años, en concreto, el crecimiento ha sido importante debido a la demanda social de nuevos productos turísticos. Gran parte del territorio cuenta con un variado patrimonio natural y cultural no suficientemente utilizado que es la base de una gran diversidad de recursos turísticos, algunos de ellos ya activados y otros con un gran potencial. El aprovechamiento turístico mas importante se da en la Sierra Norte, donde se concentra el mayor número de establecimientos y plazas de alojamiento rural rural.Rural tourism has been lately developed in the Autonomous Community of Madrid. In recent years, a significant growth has occurred due to the social demand of new tourist products. Large part of the territory has a diverse natural and cultural patrimony which is not highly harnessed but capable of turning into tourist resources. The “Sierra Norte” is the region far higher used, where the largest number of establishment and rural spaces are concentrated

Constraints and possibilities in using geographical information systems to the analysis on provision and allocation of social services

This paper is aimed to asses the value of Geographical lnformation Systems in formulating policies for planning social services (especially, their allocation and further use). Above all, we pretend to recognize the possibilities in introducing information about sociological or perceptual features and individual behavior in a G.I.S .. Besides, we try to identify the possibility of using this kind of information combined with other different data

Safety and efficacy of ribociclib plus letrozole in patients with HR+, HER2– advanced breast cancer: Results from the Spanish sub-population of the phase 3b CompLEEment-1 trial

Advanced breast cancer; CDK4/6 inhibitor; PostmenopausalCáncer de mama avanzado; Inhibidor de CDK4/6; PosmenopáusicaCàncer de mama avançat; Inhibidor de CDK4/6; PostmenopàusicaBackground Breast cancer is the most common malignancy and the second leading cause of cancer-related mortality in Spanish women. Ribociclib in combination with endocrine therapy (ET) has shown superiority in prolonging survival in patients with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2−) advanced breast cancer (ABC) vs. ET alone. Methods CompLEEment-1 is a single-arm, open-label phase 3b trial evaluating ribociclib plus letrozole in a broad population of patients with HR+, HER2– ABC. The primary endpoints were safety and tolerability. Here we report data for Spanish patients enrolled in CompLEEment-1. Results A total of 526 patients were evaluated (median follow-up: 26.97 months). Baseline characteristics showed a diverse population with a median age of 54 years. At study entry, 56.5% of patients had visceral metastases and 8.7% had received prior chemotherapy for advanced disease. Rates of all-grade and Grade ≥3 adverse events (AEs) were 99.0% and 76.2%, respectively; 21.3% of patients experienced a serious AE, and 15.8% of AEs led to treatment discontinuation. AEs of special interest of neutropenia, increased alanine aminotransferase, increased aspartate aminotransferase and QTcF prolongation occurred in 77.8%, 14.8%, 11.4% and 4.0% of patients, respectively. Patients aged >70 years experienced increased rates of all-grade and Grade ≥3 neutropenia and anemia. Efficacy results were consistent with the global study. Conclusions Results from Spanish patients enrolled in CompLEEment-1 are consistent with global data showing efficacy and a manageable safety profile for ribociclib plus letrozole treatment in patients with HR+, HER2− ABC, including populations of interest (NCT02941926).This study was funded by Novartis Pharmaceuticals. The sponsor was involved in the study design, the collection, analysis, and interpretation of data, and the writing of the manuscript

Interdisciplinary and integrative learning of neuroscience in first-year Psychology students

[EN] This work describes a novel learning experience designed by professors from four distinct first-year Psychology courses at the European University of Madrid. In general, first-year Psychology students are lacking a sense of interfield integration and unity of neuroscience. Therefore, our ultimate goal was to help students perceive continuity between neuroscience-related courses, promote interprofessionalism, and avoid compartmentalization. The specific aims were to generate transversal knowledge and integrate contents by coordinating and developing interdisciplinary learning activities. These courses share the common thread of teaching the psychological processes: sensation, perception, attention, learning and memory, as well as their biological and neurophysiological bases. This practice was designed to utilize high-impact educational methodologies based on meaningful and experiential learning approaches, in addition to active learning methods such as problem-based learning (PBL). All in all, students improved their knowledge of transversality and interprofessionalism required in learning neuroscience. Introducing these concepts in the training of first-year Psychology students may help in fostering effective strategies in the teaching of psychology.Álvarez Comino, MJ.; González Cuevas, G.; Navarro Galve, B.; Velarde Fernández, E. (2015). Interdisciplinary and integrative learning of neuroscience in first-year Psychology students. En 1ST INTERNATIONAL CONFERENCE ON HIGHER EDUCATION ADVANCES (HEAD' 15). Editorial Universitat Politècnica de València. 296-302. https://doi.org/10.4995/HEAd15.2015.41329630

Influence of Satisfaction, Expectations and Perception of Performance on University Dropout during the Pandemic

[Resumen] El abandono universitario es un área de investigación creciente debido a las diversas consecuencias negativas que puede acarrear. Se trata de un fenómeno complejo en el que intervienen múltiples variables, entre ellas factores emocionales-motivacionales. Algunas de estas variables, como la satisfacción con la educación superior y las expectativas de la titulación, son especialmente relevantes entre los estudiantes de primer curso, y más aún en un contexto de virtualidad forzada, como ha sido el caso de la crisis del COVID-19. El objetivo de este estudio es analizar la relación entre las variables emocionales-motivacionales y la intención de abandono entre un grupo de estudiantes, así como evaluar la percepción de su rendimiento académico durante la pandemia. La muestra del estudio estuvo formada por 513 estudiantes de primer y segundo curso de diferentes titulaciones de Ciencias Sociales y Ciencias de la Salud de dos universidades públicas españolas. Se utilizó un cuestionario ad hoc para medir la intención de abandono y su relación con una serie de variables. Se realizaron análisis descriptivos y modelización en árbol de decisión. Los resultados revelan que las variables predictoras más significativas para explicar la intención de abandono son la satisfacción con la elección de la titulación, las expectativas y el aprendizaje de conocimientos relevantes para su futuro profesional. También se encontró que la percepción de los estudiantes de que su rendimiento académico había disminuido durante el COVID-19 era uno de los predictores del abandono.[Abstract] University dropout is a growing area of research owing to the diverse negative consequences it can entail. It is a complex phenomenon involving multiple variables, including emotional-motivational factors. Some of these variables, such as satisfaction with higher education and expectations of the degree, are especially relevant among first-year students, and even more so in a context of forced virtualization, as has been the case during the COVID-19 crisis. The aim of this study is to analyse the relationship between emotional-motivational variables and dropout intention among a group of students, and to assess their perception of their academic performance during the pandemic. The sample for the study comprised 513 first- and second-year students from different Social Sciences and Health Sciences degrees at two Spanish public universities. An ad hoc questionnaire was used to measure dropout intention and its relationship with a series of variables. Descriptive analyses and decision tree modelling were performed. The results reveal that the most significant predictor variables to explain dropout intention are satisfaction with degree choice, expectations, and learning knowledge that is relevant to their professional future. Students’ perception that their academic performance had decreased during COVID-19 was also found to be one of the predictors of dropout

Simultaneous imaging of hard and soft biological tissues in a low-field dental MRI scanner

[EN] Magnetic Resonance Imaging (MRI) of hard biological tissues is challenging due to the fleeting lifetime and low strength of their response to resonant stimuli, especially at low magnetic fields. Consequently, the impact of MRI on some medical applications, such as dentistry, continues to be limited. Here, we present three-dimensional reconstructions of ex-vivo human teeth, as well as a rabbit head and part of a cow femur, all obtained at a field strength of 260 mT. These images are the first featuring soft and hard tissues simultaneously at sub-Tesla fields, and they have been acquired in a home-made, special-purpose, pre-medical MRI scanner designed with the goal of demonstrating dental imaging at low field settings. We encode spatial information with two pulse sequences: Pointwise-Encoding Time reduction with Radial Acquisition and a new sequence we have called Double Radial Non-Stop Spin Echo, which we find to perform better than the former. For image reconstruction we employ Algebraic Reconstruction Techniques (ART) as well as standard Fourier methods. An analysis of the resulting images shows that ART reconstructions exhibit a higher signal-to-noise ratio with a more homogeneous noise distribution.We thank anonymous donors for their tooth samples, Andrew Webb and Thomas O'Reilly (LUMC) for discussions on hardware and pulse sequences, and Antonio Tristan (UVa) for information on reconstruction techniques. This work was supported by the European Commission under Grants 737180 (FET-OPEN: HISTO-MRI) and 481 (ATTRACT: DentMRI). Action co-financed by the European Union through the Programa Operativo del Fondo Europeo de Desarrollo Regional (FEDER) of the Comunitat Valenciana 2014-2020 (IDIFEDER/2018/022). 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