Resultados a largo plazo de la ablación con catéter de la fibrilación auricular en el Hospital Miguel Servet

La ablación con catéter de la fibrilación auricular es una técnica que comenzó a llevarse a cabo hace dos décadas como alternativa al tratamiento farmacológico antiarrítmico. En el Hospital Universitario Miguel Servet de Zaragoza se realiza esta técnica desde marzo de 2014. Este trabajo pretende estudiar los resultados en este centro tras un periodo de seguimiento de hasta 6 años (media de 2,97 ± 1,64 años) en función de eficacia y complicaciones, así como contrastarlos con estudios llevados a cabo previamente en otros centros. Se trata de un estudio observacional retrospectivo en el que se incluyen las 207 intervenciones realizadas en nuestro centro desde marzo de 2014 hasta diciembre de 2019, con un periodo de seguimiento hasta mayo de 2020. Tras el análisis estadístico, se objetivó que la ablación con catéter de la fibrilación auricular puede llegar a ser curativa en el 39,3% de los pacientes. Sin embargo, las recurrencias continúan siendo un problema clínico significativo y un campo de investigación abierto hoy en día. Aun con todo, gran parte de la relevancia de esta técnica radica en que, pese a no eliminar la arritmia en un porcentaje elevado de los casos, sí que produce una mejora en la calidad de vida de los pacientes que se someten a la intervención, basada en una disminución significativa de los episodios arrítmicos, de la sintomatología y de la medicación, lo que probablemente comporta descenso de la carga asistencial y del gasto sanitario.<br /

Mineralogical and petrographic characterization of the Cerrillo Blanco Iberian sculptures

This research was funded by the following projects: (ECODIGICOLOR), grant number TED2021‑132023B‑I00, supported MCIN/AEI /http://dx.doi.org/10.13039/501100011033 and Unión Europea NextGenerationEU/ PRTR (Proyectos estratégicos orientados a la transición ecológica y digital) and project “Aplicación avanzada de las algas procedentes de la Alhambra y el Generalife en técnicas artísticas y de conservación‑restauración, (FICOARTE2), grant number P18‑FR‑4477, supported by Consejería de Universidad, Investigacion e Innovación, Junta de Andalucía, Programa FEDER, “Andalucía se mueve con Europa”, Grant PID2020‑113022GB‑I00 funded by MCIN/AEI/10.13039/501100011033 and by “ERDF A way of making Europe”, by the “European Union”.The archaeological heritage at Cerrillo Blanco (Porcuna, Spain) is made up of 27 sculptural ensembles and hundreds of fragments dated between the seventh and second centuries BC. They represent a fundamental milestone in Iberian art and culture. Despite their relevance, no scientific studies have been carried out to date in order to fully understand the materials, intentions and techniques that led to their creation. This is a study carried out on original pieces from the Archaeological Museum of Jaen using stereoscopic optical microscopy (SOM), polarised optical microscopy (POM), X-ray diffraction analysis (XRD), Fourier-transform infrared spectroscopy (FTIR), field emission scanning electron microscopy with energy dispersive x-ray analysis (FESEM-EDX) and spectrophotometry (SF). The results obtained provide new information on the material composition of this important legacy of the Iberian civilization as well as its main alteration factors.MCIN/AEI TED2021-132023B-I00, PID2020-113022GB-I00Unión Europea NextGenerationEU/ PRTR TED2021-132023B-I00Junta de Andalucía, FEDER, "Andalucía se mueve con Europa" P18-FR-4477"ERDF A way of making Europe" Unión Europea PID2020-113022GB-I0

Math anxiety and its relationship to inhibitory abilities and perceived emotional intelligence

Título: Ansiedad matemática y su relación con capacidades inhibitorias e inteligencia emocional percibida. Resumen: La ansiedad a las matemáticas es un problema emocional que repercute negativamente en el rendimiento académico de los estudiantes en distintos niveles educativos. El presente estudio analiza la relación entre este tipo de ansiedad y ciertos procesos cognitivos y emocionales. En primer lugar se pretendía determinar la relación entre la ansiedad a las matemáticas y ciertas habilidades inhibitorias dirigidas a eliminar o evitar el acceso a la conciencia de pensamientos intrusivos. En segundo lugar, interesaba comprobar la posible relación de la ansiedad a las matemáticas con la propia percepción del estudiante de sus habilidades emocionales. A tal fin se administraron a 187 estudiantes de primer curso del Grado de Psicología diferentes medidas de ansiedad a las matemáticas, a la estadística, de habilidades inhibitorias y de inteligencia emocional percibida. Los resultados mostraron que los estudiantes con puntuaciones más altas en ansiedad a las matemáti-cas presentaban una mayor susceptibilidad a experimentar pensamientos intrusivos, una menor eficacia a la hora de suprimirlos así como puntuaciones inferiores en comprensión y regulación de sus emociones. Los procesos inhibitorios y emocionales estudiados pueden resultar útiles para entender la naturaleza de la ansiedad matemática. Palabras clave: Ansiedad matemática; inhibición; pensamientos intrusivos; inteligencia emocional percibida. Abstract: Math anxiety has been found to be an emotional problem that has a negative effect on students&apos; academic performance across different levels of education. This type of anxiety could be related to certain cognitive and emotional processes. A first objective was to examine the relationship between math anxiety and certain inhibitory abilities responsible of eliminating intrusive thoughts or preventing them access to consciousness. A second aim was to determine the extent in which math anxiety and students&apos; self-perceptions of their own emotional abilities are related. To this end, 187 first-year undergraduate psychology students were administered different measures to assess math anxiety, statistics anxiety, inhibitory abilities, and perceived emotional intelligence. The results showed that students with high math anxiety were more likely to experience intrusive thoughts, were less effective at suppressing these thoughts, and reported lower scores in understanding and regulating their emotions. These cognitive mechanisms and emotional abilities are of relevance to better understand the nature of this type of anxiety

Electrochemical characterization of biodeterioration of paint films containing cadmium yellow pigment

[EN] The voltammetry of microparticles (VMP) methodology was used to characterize the biological attack of different bacteria and fungi to reconstructed egg tempera and egg linseed oil emulsion paint films containing cadmium yellow (CdS), which mimic historical painting techniques. When these paint films are in contact with aqueous acetate buffer, different cathodic signals are observed. As a result of the crossing of VMP data with attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR), scanning electrochemical microscopy (SECM), field emission scanning electron microscopy (FESEM), and atomic force microscopy (AFM), these voltammetric signals can be associated with the reduction of CdS and different complexes associated to the proteinaceous and fatty acid fractions of the binders. After biological attack with different fungi (Acremonium chrysogenum, Aspergillus niger, Mucor rouxii, Penicillium chrysogenum, and Trichoderma pseudokoningii) and bacteria (Arthrobacter oxydans, Bacillus amyloliquefaciens, and Streptomyces cellulofans), the observed electrochemical signals experience specific modifications depending on the binder and the biological agent, allowing for an electrochemical monitoring of biological attack.Financial support from the MINECO Projects CTQ2014-53736-C3-1-P and CTQ2014-53736-C3-2-P which are supported with ERDF funds is gratefully acknowledged. The authors also wish to thank Dr. José Luis Moya López, Mr. Manuel Planes Insausti, and Mrs. Alicia Nuez Inbernón (Microscopy Service of the Universitat Politècnica de València) for technical support.Ortiz-Miranda, A.; Domenech Carbo, A.; Domenech Carbo, MT.; Osete Cortina, L.; Valle-Algarra, FM.; Bolivar Galiano, F.; Martin Sanchez, I.... (2016). 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Biomedical Semantic Information Retrieval

El Buscador Semántico Biomédico propone una herramienta web de sencilla utilización para la identificación de terminología médica, la recuperación de literatura especializada y la exploración semántica del contenido gracias a la integración, con requisitos de tiempo de respuesta y alta disponibilidad, de ontologías médicas, técnicas de análisis de texto, reconocimiento de entidades y búsqueda de información sobre fuentes diversas externas. El resultado es una aplicación intuitiva y a la vez potente, que permite identificar la terminología médica sobre cualquier texto con un solo “click”. Sobre ese reconocimiento, se permite filtrado de sentidos y subconceptos y la recuperación de información sobre recursos como SciELO, Google Scholar y Medline. Además, el sistema genera un grafo conceptual de manera automática, que permite relacionar semánticamente los términos que aparecen en el texto.The Biomedical Semantic Information Retrieval system is an easy web solution to medical term identification, retrieval of specialized literature and semantic concept browsing thanks to the integration, with constraints in speed and high availability, of medical ontologies, text analysis, entity recognition and information retrieval from multiple sources. The result is an intuitive application, yet powerful, that performs term identification of medical concepts over any text with a simple click. Over identified terms the user is able conduct sub-concept selection to fine-tune the retrieval process over resources like SciELO, Google Scholar and Medline. Besides, the system generates a conceptual graph automatically which semantically relates all the terms found in the text.Este trabajo está parcialmente subvencionado por el proyecto REDES (TIN2015-65136-C2-1-R) del MICINN del Gobierno de España

Metodologías de estudio del Biodeterioro utilizadas para la investigación mediante electróquímica

Metodologías para el estudio de biodeterioro en obras de arte pictóricas y objetos arqueológicos mediante la emulación de procesos reales es lo que queremos mostrar en este trabajo. Este estudio experimental se basa en la inoculación e incubación de microorganismos procedentes de cepas de colección y obras reales en diversos sustratos propios de las obras pictóricas (barnices naturales y sintéticos, pigmentos y aglutinantes) sobre soporte lígneo, madera y vidrio. Los procesos de alteración producidos son analizados con técnicas de microscopia óptica con luz visible y luz ultravioleta (MO), microscopía electrónica de barrido/análisis elemental por energía dispersiva de rayos X (SEM/EDX), microscopia electrónica de barrido de presión variable (VP-SEM/EDX), microscopía electrónica por emisión de campo (FE-SEM), cromatografía de gases-espectrometría de masas (GC-MS), espectroscopía de infrarrojos y micro-Raman (MRS) y como rasgo innovador su aplicación en el campo de la nanaoelectroquómica con las técnicas de microscopia electroquímica de barrido (SECM) y voltamperometría de micropartículas (VPM) y mediante técnicas de Biología Molecular, que han permitido complementar resultados obtenidos previamente con las técnicas convencionales, aportando datos novedosos sobre los procesos de biodeterioro en obras de arte pictóricas y arqueológica, tanto metálicas como pétreas

Prevalence of gastro-esophageal reflux symptoms and associated factors : a population survey in the principal cities of Colombia

Problema: el reflujo gastroesofágico es un proceso fisiológico que en algunas personas puede tornarse pato-lógico y que produce molestias y lesiones esofágicas y extraesofágicas que afectan la calidad de vida de los individuos que lo presentan. Actualmente no se cuenta con estadísticas sobre la frecuencia de esta condición en Colombia. Objetivo: cuantificar la prevalencia de síntomas de enfermedad por reflujo gastroesofágico (ERGE) en los adultos de cuatro ciudades principales de Colombia utilizando el cuestionario GERDQ, y explorar la asociación de variables sociodemográficas y antropométricas con esta enfermedad. Metodología: estudio de corte transversal de base poblacional. Se incluyeron 6842 personas, mayores de 18 años y menores de 80 años de edad, residentes en Bogotá, Cali, Medellín y Barranquilla. La muestra fue seleccionada por muestreo aleatorio estratificado. Se aplicó una encuesta telefónica que incluía el cues-tionario GERDQ para la identificación de síntomas de reflujo en la última semana. Se calculó la prevalencia de reflujo por estratos teniendo en cuenta el punto de corte de la encuesta (8 o más puntos) y se realizaron comparaciones entre ellos utilizando la prueba de x2. Se exploró la asociación de variables sociodemográfi-cas y antropométricas mediante análisis bivariados y modelos de regresión logística. Resultados: se obtuvieron 6842 encuestas. La prevalencia estimada de síntomas de reflujo en general fue del 11,98% (IC 95%: 11,05-12,97). En el análisis por ciudades, Barranquilla presentó la frecuencia más alta (16,22%; IC 95%: 14,58-18,01) y Bogotá, la más baja (10,75; IC 95%: 9,30-12,38). Para los síntomas evaluados con el cuestionario GERDQ, la prevalencia estimada fue: pirosis, 13,6% (IC 95%: 12,50-14,60); regurgitación, 16,9% (IC 95%: 15,74-17,99); epigastralgia, 16,67% (IC 95%: 15,54-17,80): náuseas, 11,4% (IC 95%: 10,46-12,35); dificultad para dormir por presentar pirosis o regurgitación, 8,17% (IC 95%: 7,36-8,97); y consumo de medicamentos adicionales a los formulados por el médico, 6,68% (IC 95%: 6,01-7,35). El sexo femenino, el vivir en Barranquilla o Medellín y el presentar una comorbilidad se asociaron estadísticamente con la presencia de reflujo. Conclusión: la prevalencia de síntomas de reflujo en cuatro ciudades capitales de Colombia, medida con el cuestionario GERDQ, de 11,98% (IC 95%: 11,05-12,97), es similar a la reportada en otros países de Latinoamérica, siendo las comorbilidades (particularmente hipertensión arterial [HTA]) el factor que más se asoció con esta condición en todos los estratos del estudio.Q4Problem: Gastroesophageal reflux is a physiological process that can become pathological in some people. It can cause discomfort and esophageal and extra-esophageal injuries and can affect the quality of life of anyone affected by it. Currently there are no statistics on the frequency of this condition in Colombia. Objective: The objective of this study was to use the GerdQ questionnaire to quantify the prevalence of gastroesophageal reflux disease symptoms in adults in four major cities of Colombia and to explore the association of sociodemographic and anthropometric variables with this disease. Methodology: This was a cross-sectional population-based study of 6,842 people between the ages of 18 years and 80 in Bogotá, Cali, Medellín and Barranquilla. The sample was selected by stratified random sampling. A telephone survey was conducted that included the GERD Q questionnaire for the identification of reflux symptoms within the week prior to an interview. The prevalence of reflux by socioeconomic strata was calculated using a cut-off point of 8 or more points. Comparisons were made among strata using the χ2 test. Associations of sociodemographic and anthropometric variables were explored through bivariate analysis and logistic regression models. Results: We obtained 6,842 surveys. The overall estimated prevalence of reflux symptoms was 11.98% (95% CI = 11.05%-12.97%). The city of Barranquilla presented the highest frequency of 16.22% (95% CI = 14.58%-18.01%) while Bogotá had the lowest of 10.75% (95% CI = 9.30%-12.38%). For symptoms evaluated with GERD-Q, the estimated prevalences were: heartburn 13.6% (95% CI = 12.50% - 14.60%), regurgitation 16.9% (95% CI = 15, 74% - 17.99%), epigastralgia 16.67% (95% CI = 15.54% -17.80%), nausea 11.4% (95% CI = 10.46% - 12.35%), difficulty sleeping due to heartburn or regurgitation 8.17% (95% CI = 7.36% -8.97%) and consumption of medications additional to those formulated by the physician 6.68% (95% CI = 6, 01% - 7.35%). Women living in Barranquilla or Medellín, had statistically significant levels of comorbidities associated with reflux. Conclusion: The prevalence of reflux symptoms in four important Colombian cities measured with the GerdQ questionnaire was 11.98% (95% CI = 11.05-12.97) which is similar to prevalences reported in other Latin American countries. Comorbidities (particularly hypertension) are the factor that was most frequently associated with this condition in all strata of the study.Revista Nacional - Indexad

Evaluation of a gelatin-based adhesive for historic paintings that incorporates citronella oil as an eco-friendly biocide

[EN] The presented study focuses on evaluating the efficiency of a gelatin-based product that incorporates a plasticizer (glycerol) and a biocide (citronella oil), proposed as an eco-friendly adhesive for polychrome decoration applied in different parts of the architectural complex of the Longshan Temple in Lukang (eighteenth century, Taiwan). Seven laboratory physico-chemical tests were performed: (a) viscosity measurement; (b) drying curves; (c) moisture content determination; (d) water vapor permeability test; (e) mechanical test; (f) adhesion test; (g) susceptibility to fungi colonization test, which provide information on the workability, water content and water barrier properties, as well as mechanical, adhesion, and the biocide properties of the proposed product. The obtained results indicate that the workability, mechanical and adhesive properties of the new adhesive are adequate. Permeability in polychromies is slightly reduced due to the additional barrier effect of the adhesive incorporated into the paint film. The efficiency of citronella oil for preventing the growth of fungus Aspergillus niger on paintings consolidated with the adhesive was also probed. In parallel to these laboratory trials, the micro-invasive tests carried out, using nanoindentation combined with atomic force microscopy (NI-AFM), provided direct evidence for the improvement in the mechanical properties induced by applying the new adhesive to the original polychromies.This work was supported by the Spanish Ministerio de Economia, Industria y Competitividad (MINECO), the Fondo Europeo de Desarrollo Regional (ERDF), and the Agencia Estatal de Investigacion (AEI).Lee, Y.; Martín Rey, S.; Osete Cortina, L.; Martín-Sánchez, I.; Domenech Carbo, MT.; Bolivar-Galiano, F. (2018). Evaluation of a gelatin-based adhesive for historic paintings that incorporates citronella oil as an eco-friendly biocide. Journal of Adhesion Science and Technology. 32(21):2320-2349. https://doi.org/10.1080/01694243.2018.1477411S23202349322

Consenso colombiano de enfermedad inflamatoria intestinal

La Enfermedad inflamatoria intestinal (EEI) es un término con el que se conocen varias entidades, las dos más importantes: la colitis ulcerativa idiopática (CUI) y la enfermedad de Crohn (EC), cuyo origen es multifactorial y se caracterizan por un fenómeno inflamatorio, crónico, recurrente, con diferentes grados de severidad del tubo digestivo; pero, además con afectación potencial de otros órganos. En la última década ha habido un renovado interés en dichas entidades, debido a un auge en medicamentos novedosos; a pesar de lo cual estas siguen siendo incurables. Lo anterior asociado a una incidencia creciente de dicha patología en nuestro país nos obliga tanto científica como moralmente a convocar a un panel de expertos para elaborar unos lineamientos básicos en el enfoque y manejo de la EEI. OBJETIVOS 1. Desarrollar un consenso adaptado a nuestro medio, basado en documentación científica de la mejor calidad disponible para el enfoque diagnóstico y el manejo médico y quirúrgico. 2. Publicar y difundir dichos lineamentos tanto a la comunidad científica como al público en general a través de foros especializados, y medios de comunicación de alta penetración. 3. Elaborar y divulgar el consenso en forma de suplemento de la Revista Colombiana de Gastroenterología, el 8 de diciembre de 2011, en medio del congreso de ACADI (Asociación Colombiana de Asociaciones del Aparato Digestivo); es el mejor homenaje que el panel multidisciplinario de expertos le puede rendir a dicho evento; pero más importante aún es el reconocimiento que se le hace a los pacientes que padecen de dicha patología en nuestro país, quienes en últimas son nuestra razón de ser. METODOLOGÍA 1. Se invitaron médicos especialistas (Clínicos y quirúrgicos), líderes de opinión e industria farmacéutica nacional, cuyo área de interés y de trabajo es la EEI. 2. Se separó y manejó independientemente desde el principio la CUI de la EC. A su vez, se dividió cada entidad por módulos, con base en el método de panel de Delphi, se nombró un coordinador por cada uno de ellos, el cual se encargó de analizar junto con su equipo la literatura, para extraer el nivel de evidencia clínica y así emitir unos conceptos preliminares. Posteriormente, todo el panel de expertos se reunió en varias jornadas y conjuntamente se revisó nuevamente la evidencia clínica y conclusiones de los diferentes módulos homogenizándolas y de una manera concertada se formularon las recomendaciones definitivas.Q4https://orcid.org/0000-0002-9219-4548Revista Nacional - Indexad

Utility of Video Capsule Endoscopy and Device Assisted Enteroscopy in Inflammatory Bowel Disease

Introduction: There is no single gold standard test for the diagnosis of Crohn’s disease. The diagnosis is based on a constellation of findings: clinical history and physical examination, laboratory tests, radiologic and endoscopic examinations, and histopathology. Most patients diagnosed with Crohn’s disease have small bowel involvement. A colonoscopy with visualization of the terminal ileum may not identify involvement of the disease in proximal segments because of its patchy pattern. Complete evaluation of the small bowel is needed in order to establish a definitive diagnosis of Crohn’s disease and determine the extent and severity of the disease and its activity at baseline so it can be monitored. Objective: To review the role of video capsule endoscopy in different clinical situations of inflammatory bowel disease (IBD): suspicion of IBD; established IBD; unclassified IBD; ulcerative colitis (including ileorectal anastomosis); complications related to the use of video capsule endoscopy in IBD