On the hadronic origin of the TeV radiation from GRB 190114C

The recently discovered TeV emission from Gamma-Ray Bursts (GRBs) hints towards a possible hadronic origin of this radiation component. We developed a Monte Carlo (MC) simulation reproducing the kinematics of photo-hadronic interactions at internal shocks, including the pair production process that the secondary gamma rays undergo in the GRB jet. We find that sub-TeV observations of GRB 190114C can be reproduced by a baryonic energy content comparable to that in sub-GeV photons and a bulk Lorentz factor $\Gamma=100$, with a ms variability timescale. Neutrino flux predictions by the model are found to be consistent with experimental upper limits set by ANTARES and IceCube

The bicyclo[2.1.1]hexan-2-one system: a new probe for the experimental and computational study of electronic effects in π-facial selectivity in nucleophilic additions

The remotely substituted 5-exo-bicyclo[2.1.1]hexan-2-one system is introduced as a new probe to study long range electronic effects on π -face selectivity during hydride reduction and a systematic computational study demonstrates good predictability at the semi-empirical level

Mentalizing subtypes in eating disorders: A latent profile analysis

Background: Mentalizing, the mental capacity to understand oneself and others in terms of mental states, has been found to be reduced in several mental disorders. Some studies have suggested that eating disorders (EDs) may also be associated with impairments in mentalizing. The aim of this work is to investigate the possible presence of mentalizing subtypes in a sample of patients with EDs. Method: A sample of patients with eating disorders (N = 157) completed a battery of measures assessing mentalization and related variables, including the Reflective Functioning Questionnaire (RFQ), the Difficulties in Emotion Regulation Strategies (DERS), the Interpersonal Reactivity Index (IRI). Clinicians rated patients in relation to imbalances in different dimensions of mentalization to prementalizing modes and attachment style by using the Mentalization Imbalances Scale, the Modes of Mentalization Scale (MMS), and the Adult Attachment Questionnaire. A latent profile analysis was conducted to test the possible presence of different subgroups. MANOVA was used to test the possible differences between the four mentalizing profiles in relation to emotion dysregulation (DERS), empathy (IRI), and adequate and impairments in mentalizing (MMS and RFQ). Results: The latent profile analysis suggested the presence of four different profiles in relation to impairments in the dimensions of mentalization: (1) affective/self/automatic imbalances, (2) external imbalance, (3) cognitive/self/automatic imbalances, and (4) cognitive/other/automatic imbalances. Patients belonging to profile 1 are characterized by the prevalence of affective mentalization that overwhelms the capacity to reflect on mental states with an imbalance on the self-dimension; profile 2 patients are excessively focused on the external cues of mentalization; profile 3 patients are characterized by an over-involvement on the cognitive and self-facets of mentalization, with an impairment in adopting the other mind perspective; and profile 4 patients have similar impairments compared to profile 3 patients but with an excessive focus on others and deficits in self-reflection. These profiles were heterogeneous in terms of EDs represented in each group and presented significant differences on various variables such as attachment style, emotion dysregulation, empathy, interpersonal reactivity, and reflective function. This study represents, so far, the first work that confirms the presence of different mentalizing patterns in ED patients. Conclusions: ED patients can be classified in relation to impairments in different dimensions of mentalization above and beyond ED diagnosis

Senior management model applied to micro, small and medium business

Siendo Colombia un país cuya economía se soporta en empresas de pequeña escala, donde las MIPYMES en conjunto representando el 90%, sector que genera el 73% de empleos y el 53% de la producción bruta en los diferentes sectores industriales, comerciales y de los servicios. No obstante de la importancia de este sector en la economía, muchas de ellas enfrentan una problemática que interrumpen su crecimiento y desarrollo. Este trabajo de investigación tiene como finalidad estructurar un modelo gerencial, el cual recoge aspectos importantes y valiosos a tener en cuenta por los dueños, gerentes y administradores; producto de identificar las debilidades que han impedido su crecimiento y desarrollo de manera efectiva en el campo empresarial moderno. Por lo anterior se analizó como debilidades más sentidas el desconocimiento y aplicación de teorías actuales en materia gerencial, que pueden actuar en miras de un mayor crecimiento y diversificación de sus ofertas de bienes y servicios, en este caso en el campo de los cosméticos; Soportado en los conocimientos adquiridos durante la Especialización en Alta Gerencia, se define desde un punto de vista particular pero responsable, los temas que deberían ser revisados por este tipo de empresas, para lograr la mejor comprensión y aplicación de temas tan importantes como Pensamiento Complejo, Análisis y Estudios de Competencias, Planeamiento Estratégico y Financiero, Gerencia de Mercado y Talento Humano.Colombia is a country whose economy is supported in small scale enterprises, where MIPYMES altogether representing 90%, sector that generates 73% of jobs and 53% of gross in the various sectors of industrial, commercial production and services. But the importance of this sector in the economy, many of them face problems that disrupt their growth and development. This research paper aims to structure a management model, which collects valuable and important aspects to be considered by owners and managers; product identify the weaknesses that have prevented its growth and development effectively in the modern business field. Therefore analyzed as most pressing weaknesses lack of knowledge and application of current theories in the management field, which may act in view of further growth and diversification of its offers of goods and services, in this case in the field of cosmetics; Supported the knowledge gained during the specialization in senior management, defined from a point of view responsible, but particular issues that should be reviewed by this kind of companies, to achieve better understanding and application of such important topics as complex thought, analysis and studies of competencies, strategic planning and financial, market and human resource managemen

Adaptive mesh refinement versus subgrid friction interpolation in simulations of Antarctic ice dynamics

Geophysical Research Letters

Change of the ice rheology with climatic transitions – implication on ice flow modelling and dating of the EPICA Dome C core

International audienceThe study of the distribution of the crystallographic orientations (the fabric) along ice cores supplies information on the past and current ice flows of ice-sheets. Beside the usually observed formation of a vertical single maximum fabric, the EPICA Dome Concordia ice core (EDC) shows an abrupt and unexpected strenghtening of its fabric during termination II around 1750 m depth. Such strengthenings were already observed for sites located on an ice-sheet. This suggests that horizontal shear could occur along the EDC core. Moreover, the change in the fabric leads to a modification of the viscosity between neighbouring ice layers. Through the use of an anisotropic ice flow model, we quantify the change in viscosity and investigate its implication on ice flow and dating

Change in ice rheology during climate variations – implications for ice flow modelling and dating of the EPICA Dome C core

The study of the distribution of crystallographic orientations (i.e., the fabric) along ice cores provides information on past and current ice flow in ice-sheets. Besides the usually observed formation of a vertical single maximum fabric, the EPICA Dome C ice core (EDC) shows an abrupt and unexpected strengthening of its fabric during termination II around 1750 m depth. Such strengthening has already been observed for sites located on an ice-sheet flank. This suggests that horizontal shear could occur along the EDC core. Moreover, the change in the fabric leads to a modification of the effective viscosity between neighbouring ice layers. Through the use of an anisotropic ice flow model, we quantify the change in effective viscosity and investigate its implication for ice flow and dating

Generalization of the Luttinger Theorem for Fermionic Ladder Systems

We apply a generalized version of the Lieb-Schultz-Mattis Theorem to fermionic ladder systems to show the existence of a low-lying excited state (except for some special fillings). This can be regarded as a non-perturbative proof for the conservation under interaction of the sum of the Fermi wave vectors of the individual channels, corresponding to a generalized version of the Luttinger Theorem to fermionic ladder systems. We conclude by noticing that the Lieb-Schultz-Mattis Theorem is not applicable in this form to show the existence of low-lying excitations in the limit that the number of legs goes to infinity, e.g. in the limit of a 2D plane.Comment: RevTex, 4 pages with 4 eps figure

Mesenchymal stem cell therapy promotes renal repair by limiting glomerular podocyte and progenitor cell dysfunction in adriamycin-induced nephropathy

n/

Classification and Stability of Phases of the Multicomponent One-Dimensional Electron Gas

The classification of the ground-state phases of complex one-dimensional electronic systems is considered in the context of a fixed-point strategy. Examples are multichain Hubbard models, the Kondo-Heisenberg model, and the one-dimensional electron gas in an active environment. It is shown that, in order to characterize the low-energy physics, it is necessary to analyze the perturbative stability of the possible fixed points, to identify all discrete broken symmetries, and to specify the quantum numbers and elementary wave vectors of the gapless excitations. Many previously-proposed exotic phases of multichain Hubbard models are shown to be unstable because of the ``spin-gap proximity effect.'' A useful tool in this analysis is a new generalization of Luttinger's theorem, which shows that there is a gapless even-charge mode in any incommensurate N-component system.Comment: 15 pages revtex. Final version as publishe