AJUSTES DE MODELOS VOLUMÉTRICOS PARA O CLONE Eucalyptus grandis x E. urophylla CULTIVADOS NO AGRESTE DE PERNAMBUCO

This research aimed to evaluate the volumetric models fitting for Eucalyptus clone using normal and t-Student distributions, based on data from an experiment implanted at the Agronomic Institute of Pernambuco (IPA) in São Bento do Una, PE. In order to set the modified volumetric models of Silva and Bailey, modified Chapman and Richard, Schumacher and Hall, and modified Brody, we used data from 62 trees rigorously scaled by Smalian method. The criteria for equation comparing were the weighted value (PV) between the corrected index adjustment (IAc) and absolute mean error percentage (EPAM). According to the results, the model that best fits for the two distributions is Schumacher and Hall, with better adjustment related to the Student-t distribution. The t-Student distribution promoted improvements of equations regarding the Normal distribution, compared to the two distributions per equation.O presente trabalho teve como objetivo avaliar o ajuste de modelos volumétricos para um clone de Eucalyptus usando distribuição normal e t-Student, utilizando dados de um experimento implantado no Instituto Agronômico de Pernambuco (IPA) em São Bento do Una, PE. Para o ajuste dos modelos volumétricos de Silva e Bailey modificado, Chapman e Richard modificado, Schumacher e Hall e, Brody modificado, foram utilizados dados de 62 árvores cubadas rigorosamente pelo método de Smalian. Os critérios usados nas comparações das equações foi o valor ponderado (VP) entre o Índice de Ajuste corrigido (IAc) e o erro percentual absoluto médio (EPAM). De acordo com os resultados o modelo que mostrou melhores ajustes nas duas distribuições foi o de Schumacher e Hall, com melhores ajuste quando da distribuição t-Student. A distribuição t-Student promoveu melhorias nos ajustes das equações em relação à distribuição Normal, quando comparando as duas distribuições em cada equação.AbstractAdjustment of volumetric models for clone of Eucalyptus grandis x E. Urophylla grown on agreste, Pernambuco. This research aimed to evaluate the volumetric models fitting for Eucalyptus clone using normal and t-Student distributions, based on data from an experiment implanted at the Agronomic Institute of Pernambuco (IPA) in São Bento do Una, PE. In order to set the modified volumetric models of Silva and Bailey, modified Chapman and Richard, Schumacher and Hall, and modified Brody, we used data from 62 trees rigorously scaled by Smalian method. The criteria for equation comparing were the weighted value (PV) between the corrected index adjustment (IAc) and absolute mean error percentage (EPAM). According to the results, the model that best fits for the two distributions is Schumacher and Hall, with better adjustment related to the Student-t distribution. The t-Student distribution promoted improvements of equations regarding the Normal distribution, compared to the two distributions per equation.Keywords: Forest management; symmetric distributions; volume equations

Poliangiite microscópica com síndrome pulmão-rim: relato de caso e revisão de literatura

Microscopic polyangiitis (MPA) is a pauci-immune systemic necrotizing vasculitis associated with neutrophil anti-cytoplasmic antibody (ANCA) with a preference for small vessels. Case report: We report the case of a 54-year-old woman, who presented migratory polyarthritis in wrists, knees and ankles associated with progressive morning stiffness, with history of malar "rash", photosensitivity and alopecia. It progressed throughout the year of 2017 with deterioration of renal function and pulmonary hemorrhage, requiring intensive care. Renal biopsy suggested a pattern compatible with pauci-immune glomerulonephritis and the diagnosis of microscopic polyangiitis was suggested. She underwent pulse therapy with methylprednisolone and cyclophosphamide, in addition to plasmapheresis, being discharged from hospital after stabilization of the clinical condition. Importance of the issue: The present case reveals an uncommon and high morbimortality complication of MPA. The negativity of the ANCA made diagnosis difficult, and a renal biopsy was necessary to confirm diagnosis. Lung-kidney syndrome is potentially fatal if the treatment is not instituted early.A poliangiite microscópica (PAM) é uma vasculite necrosante sistêmica pauci-imune associada ao anticorpo anticitoplasma de neutrófilos (ANCA) com preferência de pequenos vasos. Relato do caso: Relatamos o caso de uma paciente do sexo feminino, 54 anos, que apresentou quadro de poliartrite migratória em punhos, joelhos e tornozelos associada à rigidez matinal progressiva, com histórico de “rash” malar, fotossensibilidade e alopecia. Progrediu ao longo do ano de 2017 com deterioração da função renal e hemorragia pulmonar, necessitando de cuidados intensivos. A biópsia renal sugeriu padrão compatível com glomerulonefrite pauci-imune e o diagnóstico de poliangiite microscópica foi aventado. Realizou pulsoterapia com metilprednisolona e ciclofosfamida, além de plasmaférese, recebendo alta após estabilização do quadro clínico. Importância do problema: O presente caso ilustra uma complicação incomum e de elevada morbimortalidade da PAM. A negatividade do ANCA dificultou o diagnóstico, sendo necessária a realização de biópsia renal com confirmação diagnóstica. A síndrome pulmão-rim apresenta evolução potencialmente fatal se não instituído precocemente o tratamento

GASTROINTESTINAL PARASITES OF Iguana iguana LINNAEUS, 1758 (SQUAMATA: IGUANIDAE) OF THE URBAN AREA OF TERESINA, PIAUÍ, BRAZIL

Estudos sobre as relações parasito-hospedeiro são um dos fatores responsáveis para a compreensão das variações que ocorrem na dinâmica populacional das estruturas da comunidade de vertebrados. Infecções por parasitos influenciam o controle da população dos seus hospedeiros. O objetivo do presente trabalho foi identificar a fauna parasitária em Iguana-verde (Iguana iguana) da zona urbana em Teresina-PI. No total foram capturadas 15 iguanas, 06 na Avenida Maranhão e 09 nas regiões da UESPI. Foram encontrados ovos de oxiurídeos pelo método de Hoffmann e técnica de Willis-Mollay modificado. Os helmintos encontrados foram os oxiurídeos: Ozolaimus cirratus no intestino grosso e delgado das iguanas parasitadas e Ozolaimus megatyphlon somente no intestino grosso. Neste trabalho relatamos pela primeira vez a ocorrência do gênero Ozolaimus em iguanas piauienses. A Avenida Maranhão é um local altamente antropogênico, consequentemente altera o habitat nativo do animal, revelando a importância desses animais estarem em seu ambiente natural ou menos antropogênico.Palavras-chave: Répteis, Iguana iguana, helmintos, oxiurídeos, Ozolaimus.Studies on host-parasite relationships are one of the factors responsible for understanding the variations that occur in the population dynamics of vertebrate community structures. Infections by parasites influence the control of the population of their hosts. The objective of the present work was to identify the parasitic fauna in Iguana-verde (Iguana iguana) of the urban zone in Teresina-PI. In total, 15 iguanas were captured, 06 on Maranhão Avenue and 09 in the UESPI regions. Oxyurid eggs were found by the method of Hoffmann and modified Willis-Mollay technique. The helminths found were the oxyurids: Ozolaimus cirratus in the large and small intestine of the parasitized iguanas and Ozolaimus megatyphlon only in the large intestine. In this work we report for the first time the occurrence of the genus Ozolaimus in iguanas piauienses. Maranhão Avenue is a highly anthropogenic place, consequently alters the native habitat of the animal, revealing the importance of these animals in their natural or less anthropogenic environment.Keywords: Reptiles; Iguana iguana; helminths; oxyurids; Ozolaimus

COVID-19 IN INFLAMMATORY BOWEL DISEASE: SHOULD WE BE MORE CAREFUL WITH THE USE OF SALICYLATES?

ABSTRACT Backgrounds: Fortunately, much has been studied about COVID-19 in patients with inflammatory bowel diseases (IBD). Evidence suggests that these patients do not appear to be at increased risk of severe COVID-19. However, there are still some uncertainties regarding the clinical manifestations of COVID-19 in patients with immune-mediated diseases. Objective: This study aimed to describe the main symptoms of COVID-19 and their frequency in IBD patients and evaluate the impact of the IBD therapeutic drugs on clinical presentation of COVID-19 and to determine factors associated with COVID-19 in this population. Methods: Adult patients with IBD from three tertiary-care public, teaching hospitals in Ceará, Northeastern Brazil, were evaluated during one scheduled appointment from March to December 2020. Patients with possible or confirmed COVID-19 were compared with patients without COVID-19. Furthermore, incidences of each symptom were evaluated based on the use of IBD therapeutic drugs. Results: A total of 515 patients with IBD were included in the study: 234 with CD, and 281 with UC. Of these, 174 patients (34%) had possible/confirmed COVID-19 of whom 156 (90%) were symptomatic. Main symptoms were fever (65%) and headache (65%); gastrointestinal symptoms occurred in one third of patients and were higher than COVID-19 in general population. The factors associated with having COVID-19 were female gender (OR 1.71, 95%CI: 1.17-2.50); contact at home (OR 5.07, 95%CI: 3.31-7.78) and outside the home (OR 3.14, 95%CI: 2.10-4.71) with a case of COVID-19; work outside of the home (OR 1.87, 95%CI: 1.26-2.78); family history of COVID-19 (OR 2.29, 95%CI 1.58-3.33) use of salicylate (OR 1.71, 95%CI: 1.17-4.28); and asthma (OR 7.10, 95%CI: 1.46-34.57). Conclusion: IBD patients at high risk of COVID-19 infection may need to avoid salicylate therapy but further studies are necessary to confirm this association

Catálogo Taxonômico da Fauna do Brasil: setting the baseline knowledge on the animal diversity in Brazil

The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others

Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030

Alterações do peridomicílio e suas implicações para o controle do Triatoma brasiliensis Peridomiciliary changes and implications for Triatoma brasiliensis control

Em Boa Viagem, Ceará, foram investigados e rociados 9.906 anexos dos peridomicílios de 1.541 vivendas rurais em área infestada por Triatoma brasiliensis e/ou Triatoma pseudomaculata com revisões aos 6, 12 e 18 meses. Observou-se um decréscimo do número de anexos nos 18 meses, mais intenso para anexos tipo "pilhas de materiais". De modo geral, a população só modificou 3% dos anexos, principalmente os abrigos de animais (6%). A construção de anexos novos foi importante como causa de novas infestações, significativamente mais presentes nestes (25%) que naqueles que existiam desde o início da observação (4%), provavelmente por conta do expurgo inicialmente realizado. A reinfestação ocorreu lentamente, sendo mais freqüente nos abrigos de animais (7,0%) que em pilhas (4,4%) e em cercas e cobertas (<1%). A densidade da reinfestação sempre foi baixa, independente da espécie do triatomíneo ou do tipo do anexo. Em um estudo colateral, um ensaio pareado com a borrifação inicial de piretróide versus composto organofosforado em matriz de lenta liberação não mostrou diferenças de infestação nem de densidade triatomínica ao final do experimento. Sugere-se a borrifação seletiva de anexos novos tão logo sejam construídos, em áreas semelhantes à deste estudo.<br>A total of 9,906 annexes from 1,541 rural dwellings of Boa Viagem County, Ceará, Brazil, infested by Triatoma brasiliensis and Triatoma pseudomaculata were investigated and immediately sprayed with pyrethroid insecticide, followed by revisions at 6, 12, and 18 months. The initial infestation rate of annexes was 4.0%, with predominant infestation in animal shelters (7.0%). Mean insect density was low, regardless of triatomine species or type of annex. A progressive decrease in the number of initial annexes was observed (66% of remaining annexes), mainly those classified as "piles of materials". Only 3% of the annexes were modified by the population. New constructed annexes were important as new foci of infestation. Some 25% were infested at the end of observation period, significantly more than the "old" annexes (4.0%), a difference attributed to insecticide spraying at the beginning of the intervention. Reinfestation occurred slowly and was more frequent in animal shelters No differences were observed between traditional pyrethroid and slow-release organophosphate formulations. Selective spraying of "new" annexes is recommended

Alterações do peridomicílio e suas implicações para o controle do Triatoma brasiliensis

Em Boa Viagem, Ceará, foram investigados e rociados 9.906 anexos dos peridomicílios de 1.541 vivendas rurais em área infestada por Triatoma brasiliensis e/ou Triatoma pseudomaculata com revisões aos 6, 12 e 18 meses. Observou-se um decréscimo do número de anexos nos 18 meses, mais intenso para anexos tipo "pilhas de materiais". De modo geral, a população só modificou 3% dos anexos, principalmente os abrigos de animais (6%). A construção de anexos novos foi importante como causa de novas infestações, significativamente mais presentes nestes (25%) que naqueles que existiam desde o início da observação (4%), provavelmente por conta do expurgo inicialmente realizado. A reinfestação ocorreu lentamente, sendo mais freqüente nos abrigos de animais (7,0%) que em pilhas (4,4%) e em cercas e cobertas (<1%). A densidade da reinfestação sempre foi baixa, independente da espécie do triatomíneo ou do tipo do anexo. Em um estudo colateral, um ensaio pareado com a borrifação inicial de piretróide versus composto organofosforado em matriz de lenta liberação não mostrou diferenças de infestação nem de densidade triatomínica ao final do experimento. Sugere-se a borrifação seletiva de anexos novos tão logo sejam construídos, em áreas semelhantes à deste estudo