3,752 research outputs found
Modeling Heterogeneous Materials via Two-Point Correlation Functions: II. Algorithmic Details and Applications
In the first part of this series of two papers, we proposed a theoretical
formalism that enables one to model and categorize heterogeneous materials
(media) via two-point correlation functions S2 and introduced an efficient
heterogeneous-medium (re)construction algorithm called the "lattice-point"
algorithm. Here we discuss the algorithmic details of the lattice-point
procedure and an algorithm modification using surface optimization to further
speed up the (re)construction process. The importance of the error tolerance,
which indicates to what accuracy the media are (re)constructed, is also
emphasized and discussed. We apply the algorithm to generate three-dimensional
digitized realizations of a Fontainebleau sandstone and a boron
carbide/aluminum composite from the two- dimensional tomographic images of
their slices through the materials. To ascertain whether the information
contained in S2 is sufficient to capture the salient structural features, we
compute the two-point cluster functions of the media, which are superior
signatures of the micro-structure because they incorporate the connectedness
information. We also study the reconstruction of a binary laser-speckle pattern
in two dimensions, in which the algorithm fails to reproduce the pattern
accurately. We conclude that in general reconstructions using S2 only work well
for heterogeneous materials with single-scale structures. However, two-point
information via S2 is not sufficient to accurately model multi-scale media.
Moreover, we construct realizations of hypothetical materials with desired
structural characteristics obtained by manipulating their two-point correlation
functions.Comment: 35 pages, 19 figure
Characterisation of Vernaccia Nera (Vitis vinifera L.) grapes and wine
Vernaccia Nera (VN) is a minor Italian red grape cultivar whose oenological properties have not been investigated yet. Traditional winemaking procedures with VN can include grape drying and even triple sequential fermentations, but a rational vinification approach should be based on the grape composition. Since a comprehensive characterisation of the VN grape is still missing, the ripening of VN grapes was monitored by evaluating flavour compounds, proanthocyanidins and anthocyanins. The grapes were used to produce red wine whose chemical composition and sensory properties were assessed. Ripe VN grapes contained high amounts of extractable anthocyanins (0.88 g/kg). The most abundant anthocyanin was malvidin (56.6%), and high relative amounts of cumarate forms (11.3%) were also found. The grape skin showed a high concentration of proanthocyanidins (2 g/kg), whose degree of polymerisation was low (10.3). Epigallocatechin accounted for up to 39% of the flavan-3-ol units in the skin. Flavour compounds in the grapes included glycosylated norisoprenoids (mainly 3-oxo-alpha-ionol and vomifoliolo) and benzenoids. The VN red wine showed a high concentration of anthocyanins, but the level of proanthocyanidins (0.93 g/L) was lower than expected. The spicy flavours were the notes mostly recognised in the sensory evaluation. Our data highlight the VN grape as suitable for the production of ready-to-drink or shortly aged red wine due to its high acidity and low astringency
Fluctuations in Stationary non Equilibrium States
In this paper we formulate a dynamical fluctuation theory for stationary non
equilibrium states (SNS) which covers situations in a nonlinear hydrodynamic
regime and is verified explicitly in stochastic models of interacting
particles. In our theory a crucial role is played by the time reversed
dynamics. Our results include the modification of the Onsager-Machlup theory in
the SNS, a general Hamilton-Jacobi equation for the macroscopic entropy and a
non equilibrium, non linear fluctuation dissipation relation valid for a wide
class of systems
Tracing CP-violation in Lepton Flavor Violating Muon Decays
Although the Lepton Flavor Violating (LFV) decay is
forbidden in the Standard Model (SM), it can take place within various theories
beyond the SM. If the branching ratio of this decay saturates its present bound
[{\it i.e.,} Br], the forthcoming
experiments can measure the branching ratio with high precision and
consequently yield information on the sources of LFV. In this letter, we show
that for polarized , by studying the angular distribution of the
transversely polarized positron and linearly polarized photon we can derive
information on the CP-violating sources beyond those in the SM. We also study
the angular distribution of the final particles in the decay where is defined to be the more energetic positron. We show
that transversely polarized can provide information on a certain
combination of the CP-violating phases of the underlying theory which would be
lost by averaging over the spin of .Comment: 6 pages, 2 figure
Stochastic interacting particle systems out of equilibrium
This paper provides an introduction to some stochastic models of lattice
gases out of equilibrium and a discussion of results of various kinds obtained
in recent years. Although these models are different in their microscopic
features, a unified picture is emerging at the macroscopic level, applicable,
in our view, to real phenomena where diffusion is the dominating physical
mechanism. We rely mainly on an approach developed by the authors based on the
study of dynamical large fluctuations in stationary states of open systems. The
outcome of this approach is a theory connecting the non equilibrium
thermodynamics to the transport coefficients via a variational principle. This
leads ultimately to a functional derivative equation of Hamilton-Jacobi type
for the non equilibrium free energy in which local thermodynamic variables are
the independent arguments. In the first part of the paper we give a detailed
introduction to the microscopic dynamics considered, while the second part,
devoted to the macroscopic properties, illustrates many consequences of the
Hamilton-Jacobi equation. In both parts several novelties are included.Comment: 36 page
Mucopolysaccharidosis type II: preliminary data on glycosaminoglycan levels and structure in mice at baseline and after 6 weeks treatment with ERT
Mucopolysaccharidosis type II is a lysosomal storage disease due to the deficit of the enzyme iduronate 2-sulfatase (IDS) and to the consequent accumulation of heparan- (HS) and dermatan-sulfate (DS), with multi-organ involvement.
In this study we characterized glycosaminoglycan (GAG) levels and structure in the brain and liver of the Ids knock-out mouse model, at 12 weeks of age and after 6 weeks treatment with human IDS (hIDS) enzyme, by using the capillary electrophoresis-laser induced fluorescence (CE-LIF) technique.
As expected, Ids-ko mice showed a heavy accumulation of HS, about 15 times higher than wild-type (wt) in the brain and up to 240 times in the liver. The overall HS charge density rose by 1.5 times only in the liver, but the sulfation pattern changed in both organs. We also observed an increased chondroitin-sulfate (CS)+DS levels of about 2 times in the brain and 5 times in the liver, but an increased CS/DS ratio of about 22 times only in the liver. On the contrary, the hyaluronic acid (HA) levels did not change in both organs.
We also conducted the same analysis in Ids-ko mice treated with 1 mg/kg of hIDS, once a week. As expected, we observed in the liver a huge reduction of HS (20 times vs untreated mice) and also of CS+DS and CS/DS. Instead, we did not observe a reduction of the different GAGs in the brain, confirming the enzyme inability to cross BBB. In this district a slight increase of CS/DS ratio, CS+DS and HA levels, and an about 40% increase of HS level, vs untreated ko mice, was observed. On the opposite, the overall HS charge density is decreased 2.5X vs untreated ko and wt mice.
This preliminary data underline how by using a more sensitive technique of analysis, a clear separation of the GAGs pattern between wt and Ids-ko mice can be observed. This results particularly important for the brain, where application of common biochemical techniques detects very low GAG levels in both animal types, thus limiting the use of GAG analysis as possible biomarker of therapeutic efficacy in the brain district. The application of CE-LIF analysis is therefore proposed for a detailed evaluation of GAG pattern for potential monitoring of therapeutic efficacy
Riesgo de caries dental en pacientes de tres a seis años que acuden a la clínica de la de la Universidad Nacional Federico Villarreal
El objetivo del presente estudio fue determinar el riesgo de caries dental que presentan los pacientes de tres a seis años que acudieron a la clínica de la Universidad Nacional Federico Villarreal en el año 2011. La muestra fue de 50 niños de ambos sexos que cumplieron con los criterios de inclusión y exclusión, a quienes se les realizó una encuesta y una evaluación del índice de higiene oral para determinar la presencia y nivel de riesgo de caries dental. Los resultados obtenidos fueron que en los factores de riesgo de caries dental estudiados en la presente investigación están presentes indistintamente la edad y el sexo. El factor de riesgo más prevalente es el cepillado dental con 21 casos, seguido del factor visita al odontólogo con 19 casos. El riesgo de caries dental más prevalente es el “Riesgo Bajo” con un 40.8%, seguido de 37.6% con un “Riesgo Mediano” y 21.8% presentan “Riesgo Alto”. Al relacionar los valores se determinó que no hay diferencias significativas de los factores de riesgo de caries dental en relación al sexo, encontrándose diferencias altamente significativas entre los niveles de caries dental y la presencia de los factores de riesgo.Palabras claves: caries dental, riesgo, factores de riesg
Rayleigh loops in the random-field Ising model on the Bethe lattice
We analyze the demagnetization properties of the random-field Ising model on
the Bethe lattice focusing on the beahvior near the disorder induced phase
transition. We derive an exact recursion relation for the magnetization and
integrate it numerically. Our analysis shows that demagnetization is possible
only in the continous high disorder phase, where at low field the loops are
described by the Rayleigh law. In the low disorder phase, the saturation loop
displays a discontinuity which is reflected by a non vanishing magnetization
m_\infty after a series of nested loops. In this case, at low fields the loops
are not symmetric and the Rayleigh law does not hold.Comment: 8pages, 6 figure
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