3,954 research outputs found

    A feasibility study on using inkjet technology, micropumps, and MEMs as fuel injectors for bipropellant rocket engines

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    Control over drop size distributions, injection rates, and geometrical distribution of fuel and oxidizer sprays in bi-propellant rocket engines has the potential to produce more efficient, more stable, less polluting rocket engines. This control also offers the potential of an engine that can be throttled, working efficiently over a wide range of output thrusts. Inkjet printing technologies, MEMS fuel atomizers, and piezoelectric injectors similar in concept to those used in diesel engines are considered for their potential to yield a new, more active injection scheme for a rocket engine. Inkjets are found to be unable to pump at sufficient pressures, and have possibly dangerous failure modes. Active injection is found to be feasible if high pressure drop along the injector plate are used. A conceptual design is presented and its basic behavior assessed

    The economics of density: evidence from the Berlin Wall

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    This paper develops a quantitative model of internal city structure that features agglomeration and dispersion forces and an arbitrary number of heterogeneous city blocks. The model remains tractable and amenable to empirical analysis because of stochastic shocks to commuting decisions, which yield a gravity equation for commuting flows. To structurally estimate agglomeration and dispersion forces, we use data on thousands of city blocks in Berlin for 1936, 1986 and 2006 and exogenous variation from the city’s division and reunification. We estimate substantial and highly localized production and residential externalities. We show that the model with the estimated agglomeration parameters can account both qualitatively and quantitatively for the observed changes in city structure. We show how our quantitative framework can be used to undertake counterfactuals for changes in the organization of economic activity within cities in response for example to changes in the transport network

    High-Frequency Spin Waves in YBa₂Cu₃O\u3csub\u3e6.15\u3e/sub\u3e

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    Pulsed neutron spectroscopy is used to absolute measurements of the dynamic magnetic susceptibility of insulating YBa2Cu3O6.15. Acoustic and optical modes, derived from inand out-of-phase oscillation of spins in adjacent CuO2 planes, dominate the spectra and are observed up to 250 meV. The optical modes appear first at 74±5 meV. Linear-spin-wave theory gives an excellent description of the data and yields intralayer and interlayer exchange constants of J∥=125±5 meV and J⊄=11±2 meV, respectively, and a spin-wave intensity renormalization ZΧ=0.4±0.1

    Costs and outcomes of noncardioembolic ischemic stroke in a managed care population

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    Nicole M Engel-Nitz1, Stephen D Sander2, Carolyn Harley3, Gabriel Gomez Rey1, Hemal Shah21Health Economic and Outcomes Research, i3 Innovus, Eden Prairie, MN, USA; 2Health Economic and Outcomes Research, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, USA; 3Health Economic and Outcomes Research, i3 Innovus, Palo Alto, CA, USAPurpose: To evaluate the clinical outcomes and incremental health care costs of ischemic stroke in a US managed care population.Patients and methods: A retrospective cohort analysis was done on patients (aged 18+ years) hospitalized with noncardioembolic ischemic stroke from January 1, 2002, through ­December 31, 2003, identified from commercial health plan administrative claims. New or recurrent stroke was based on history in the previous 12 months, with index date defined as first date of ­indication of stroke. A control group without stroke or transient ischemic attack (TIA) was matched (1:3) on age, sex, and geographic region, with an index date defined as the first ­medical claim during the patient identification period. Patients with atrial fibrillation or mitral value abnormalities were excluded. Ischemic stroke and control cohorts were compared on 4-year clinical outcomes and 1-year costs.Results: Of 2180 ischemic stroke patients, 1808 (82.9%) had new stroke and 372 (17.1%) had a recurrent stroke. Stroke patients had higher unadjusted rates of additional stroke, TIA, and fatal outcomes compared with the 6540 matched controls. Recurrent stroke patients had higher rates of adverse clinical outcomes compared with new stroke patients; costs attributed to recurrent stroke were also higher. Stroke patients were 2.4 times more likely to be hospitalized in follow-up compared with controls (hazard ratio [HR] 2.4, 95% confidence interval [CI]: 2.2, 2.6). Occurrence of stroke following discharge was 21 times more likely among patients with index stroke compared with controls (HR 21.0, 95% CI: 16.1, 27.3). Stroke was also predictive of death (HR 1.8, 95% CI: 1.3, 2.5). Controlling for covariates, stroke patients had significantly higher costs compared with control patients in the year following the index event.Conclusion: Noncardioembolic ischemic stroke patients had significantly poorer outcomes and higher costs compared with controls. Recurrent stroke appears to contribute substantially to these higher rates of adverse outcomes and costs.Keywords: burden of illness, stroke⁄cerebrovascular accident, cardiovascular disease, claims analysis, costs of care, health care outcome

    Parietal Cortex Regulates Visual Salience and Salience-Driven Behavior

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    Chen et al. show that inactivation of parietal cortex selectively reduces salience signals within prefrontal cortex and diminishes the influence of salience on visually guided behavior. The results demonstrate a causal role of parietal cortex in regulating salience signals within the brain and in controlling salience-driven behavior

    Core and skin temperature influences on the surface electromyographic responses to an isometric force and position task

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    <p><b>Electromyographic responses of root-mean-square amplitude (RMS; A), mean power frequency (MPF; B) and median power frequency (MDF; C) to passive heating and cooling for the 1-minute isometric force (black bars) and position (open bars) task in 18 participants.</b> Temperature states: initial T<sub>re</sub> and (BASE); hot T<sub>re</sub>, hot (H-H); hot T<sub>re</sub>, cool (H-C); and end of the protocol where T<sub>re</sub> returned to normal and was cool (POST). <sup>a</sup>Significantly different from baseline (BASE). <sup>b</sup>Significantly different from hot core-hot skin (H-H). <sup>c</sup>Significantly different from hot core-cool skin(H-C). <sup>d</sup>Significantly different from end of protocol (POST).</p

    X-Ray Evidence for Flare Density Variations and Continual Chromospheric Evaporation in Proxima Centauri

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    Using the XMM-Newton X-ray observatory to monitor the nearest star to the Sun, Proxima Centauri, we recorded the weakest X-ray flares on a magnetically active star ever observed. Correlated X-ray and optical variability provide strong support for coronal energy and mass supply by a nearly continuous sequence of rapid explosive energy releases. Variable emission line fluxes were observed in the He-like triplets of OVII and NeIX during a giant flare. They give direct X-ray evidence for density variations, implying densities between 2x10^{10} - 4x10^{11} cm^{-3} and providing estimates of the mass and the volume of the line-emitting plasma. We discuss the data in the context of the chromospheric evaporation scenario.Comment: 10 pages, 2 figures, accepted by The Astrophysical Journal, Letters; improved calculations of radiative loss of cool plasma (toward end of paper

    Improved Performance and Stability of Organic Solar Cells by the Incorporation of a Block Copolymer Interfacial Layer

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    In a proof-of-concept study, this work demonstrates that incorporating a specifically designed block copolymer as an interfacial layer between a charge transport layer and the photoactive layer in organic solar cells can enhance the interface between these layers leading to both performance and stability improvements of the device. This is achieved by incorporating a P3HT50-b-PSSx block copolymer as an interfacial layer between the hole transporting and photoactive layers, which results in the improvement of the interfacial roughness, energy level alignment, and stability between these layers. Specifically, the incorporation of a 10 nm P3HT50-b-PSS16 and a 13 nm P3HT50-b-PSS23 interfacial layer results in a 9% and a 12% increase in device efficiency respectively compared to the reference devices. In addition to having a higher initial efficiency, the devices with the block copolymer continue to have a higher normalized efficiency than the control devices after 2200 h of storage, demonstrating that the block copolymer not only improves device efficiency, but crucially, prevents degradation by stabilizing the interface between the hole transporting layer and the photoactive layer. This study proves that appropriately designed and optimized block copolymers can simultaneously stabilize and improve the efficiency of organic solar cells
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