72 research outputs found
Circulating Endothelial Progenitor Cells in Kidney Transplant Patients
- Author
- A Siddique
- A Sturiale
- A Trapp
- Alexander Grabner
- AO Robb
- AO Spiel
- Aric Gregson
- Burkhard Greve
- C Patterson
- C Urbich
- C Urbich
- CH Wang
- Detlef Lang
- Dominik Kentrup
- F Togel
- F Zemani
- FH Bahlmann
- G Coppolino
- Giovana S. Di Marco
- GS Di Marco
- GS Di Marco
- H Kocak
- Hermann Pavenstädt
- J Lorenzen
- J Tongers
- JH Choi
- K de Groot
- K de Groot
- K Herbrig
- KA Jackson
- KE Jie
- M Buemi
- M Peichev
- Marcus Brand
- Martin Hausberg
- MJ Soler
- P Delva
- P Ochodnicky
- P Rustemeyer
- P Rustemeyer
- PE Szmitko
- PE Westerweel
- Peter Rustemeyer
- RA Wolfe
- Raphael Koch
- S Korom
- S Korom
- S Metsuyanim
- S Reuter
- S Steiner
- Stefan Reuter
- T Asahara
- T Deckert
- T Nickel
- T Takahashi
- U Cassens
- V Horcicka
- Werner Wittkowski
- Publication venue
- Public Library of Science
- Publication date
- 08/09/2011
- Field of study
Background: Kidney transplantation (RTx) leads to amelioration of endothelial function in patients with advanced renal failure. Endothelial progenitor cells (EPCs) may play a key role in this repair process. The aim of this study was to determine the impact of RTx and immunosuppressive therapy on the number of circulating EPCs.
Methods: We analyzed 52 RTx patients (58613 years; 33 males, mean 6 SD) and 16 age- and gender-matched subjects with normal kidney function (57617; 10 males). RTx patients received a calcineurin inhibitor (CNI)-based (65%) or a CNI-free therapy (35%) and steroids. EPC number was determined by double positive staining for CD133/VEGFR2 and CD34/VEGFR2 by flow cytometry. Stromal cell-derived factor 1 alpha (SDF-1) levels were assessed by ELISA. Experimentally, to dissociate the impact of RTx from the impact of immunosuppressants, we used the 5/6 nephrectomy model. The animals were treated with a CNI-based or a CNI-free therapy, and EPCs (Sca+cKit+) and CD26+ cells were determined by flow cytometry.
Results: Compared to controls, circulating number of CD34+/VEGFR2+ and CD133+/VEGFR2+ EPCs increased in RTx patients. There were no correlations between EPC levels and statin, erythropoietin or use of renin angiotensin system blockers in our study. Indeed, multivariate analysis showed that SDF-1 – a cytokine responsible for EPC mobilization – is independently associated with the EPC number. 5/6 rats presented decreased EPC counts in comparison to control animals. Immunosuppressive therapy was able to restore normal EPC values in 5/6 rats. These effects on EPC number were associated with reduced number of CD26+ cells, which might be related to consequent accumulation of SDF-1.
Conclusions: We conclude that kidney transplantation and its associated use of immunosuppressive drugs increases the number of circulating EPCs via the manipulation of the CD26/SDF-1 axis. Increased EPC count may be associated to endothelial repair and function in these patients.
The association between objective walkability, neighborhood socio-economic status, and physical activity in Belgian children
- Author
- B Giles-Corti
- B Giles-Corti
- BE Saelens
- Benedicte Deforche
- C Mattocks
- D Ding
- D Van Dyck
- Delfien Van Dyck
- F De Meester
- F De Meester
- G Grasser
- G Mecredy
- Greet Cardon
- GS Trapp
- I Janssen
- Ilse De Bourdeaudhuij
- J Kerr
- J Twisk
- J Veitch
- JB Vandendriessche
- JF Sallis
- JF Sallis
- JF Sallis
- JR Panter
- K Sundquist
- KA Tappe
- KM Robusto
- KR Evenson
- LB Christiansen
- LD Frank
- M Verloigne
- MA Winkleby
- N Owen
- NL Holt
- S D'Haese
- S Verstraete
- Sara D’Haese
- SG Trost
- SP Kremers
- T Baranowski
- V Van Holle
- VL Shavers
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)
- Author
- Abbott TE
- Abdallah RI
- Abdel-Aal IR
- Abdelmonem SA
- Abdo WF
- Abellan AN
- Abellán AN
- Abellán AN
- Abellán AN
- Abrams ST
- Ackerley C
- Acuña M
- Adda M
- Adhikari NK
- Adriano G
- Adrie C
- Affatato R
- Affatato R
- Afonso-Rivero D
- Agarossi A
- Agarwal LK
- Ageeva T
- Agrawal R
- Aguayo-DeHoyos E
- Aguilar AL
- Aguilar-Alonso E
- Aguilar-Alonso E
- Aguilar-Alonso E
- Aguirregabyria M
- Ahmadnia E
- Ahn C
- Ahn JY
- Ahn JY
- Ahn MY
- Ahn MY
- Aitken LM
- Akalaev R
- Akbarzadeh A
- Akcan-Arikan A
- Akhlagh SH
- Akhtar N
- AKI Research Group
- Akiduki N
- Akin S
- Akizuki N
- Akkoc T
- Ala-Kokko T
- Alanio A
- Albaiceta GM
- Albaladejo P
- Alberto F
- Albuisson E
- Alcala MA
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- Aldabo-Pallas T
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- Aldecoa C
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- Alejandro R
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- ARIAM registry of adult cardiac surgery
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- Hrachovina M
- Hraiech S
- Hravnak M
- Hu HC
- Hua Y
- Hualde JB
- Hualde JB
- Hualde JB
- Hualde JB
- Hualde JB
- Hualde JB
- Huang CH
- Huang WC
- Huang WC
- Huang WC
- Huang WC
- Hubbard A
- Huber W
- Huddart S
- Hull AM
- Hung CY
- Hung WT
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- Huot B
- Husheer SL
- Hutchings S
- Hutchison R
- Hwang GS
- Hwang GS
- Ibañes PG
- Ibsen M
- Idei M
- Idei M
- Idone FA
- Iesu E
- Iesu E
- Iglesias-Santiago A
- Ignacio ML
- Iida A
- Iijima H
- Ilan R
- Ilyina V
- Imanaka H
- Inaloo S
- Ince C
- Iotti GA
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- Iotti GA
- IPREA Study Group
- Irazabal JM
- Irazabal JM
- Ishimatsu S
- Itenov TS
- Iwamoto M
- Izawa M
- Izdes S
- Jaber S
- Jacky A
- Jacobs FM
- Jacques T
- Jaffal K
- Jamali S
- Jang BH
- Janotka M
- Janotka M
- Janotka M
- Jansen D
- Jansen N
- Japan Septic Disseminated Intravascular Coagulation (JSEPTIC DIC) study group
- Jardim JJ
- Jardim M
- Jareño A
- Javadpour S
- Jayasinghe S
- Jean-Baptiste S
- Jean-Baptiste S
- Jensen AE
- Jensen JU
- Jeon YD
- Jeon YD
- Jeong IY
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- Jian Z
- Jiao LR
- Jibaja M
- Jimenez-Herrera MF
- Jiménez GJ
- Jo YH
- Joachim J
- Jochmans S
- John G
- Jonas M
- Jonas M
- Jonas M
- Jones C
- Joshi R
- Joshi V
- Jovaisa T
- JSEPTIC (Japanese Society of Education for Physicians and Trainees in Intensive Care) Clinical Trial Group
- Juan WC
- Juanas CA
- Judickas S
- Juez A
- Juliarena A
- Jun IG
- Jun IG
- Jung K
- Jung KW
- Junior JM
- Kaczirek K
- Kaese S
- Kalani N
- Kalenka A
- Kalfon P
- Kamali E
- Kaminsky GE
- Kaneko M
- Kang M
- Kang M
- Kang PL
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- Kang Y
- Kao KC
- Kappler F
- Kara A
- Karachi F
- Karanjia N
- Karbing DS
- Karsten E
- Kasdan H
- Kashiya S
- Kashyap R
- Katabami K
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- Katira BH
- Kavanagh BP
- Kawamura N
- Kawano S
- Kay FU
- Kayaaslan B
- Kayambu G
- Kazutoshi F
- Ke MW
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- Keep J
- Keller E
- Kellner F
- Kelly JM
- Kenardy J
- Keough E
- Kerhuel L
- Kerr C
- Kezyte G
- Khadjibaev A
- Khaliq W
- Khine H
- Kim DJ
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- Kim MH
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- Kim W
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- King HS
- Kinnear J
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- Kirakli C
- Kirca H
- Kirman M
- Kirwan CJ
- Kittnar O
- Klapsing P
- Klaus DA
- Kleinpell R
- Kluge S
- Knafelj R
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- Ko JI
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- Kobayashi A
- Koco E
- Kodate A
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- Kokkini S
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- Komuro T
- Kondili E
- Kongpolprom N
- Kooner G
- Kostalas M
- Kosuk ME
- Kotsopoulos A
- Kou PS
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- Kovacikova L
- Kox M
- Kraegpoeth A
- Krenn CG
- Krishna B
- Kristof J
- Kruger A
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- Krüger A
- Ku NS
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- Kubik M
- Kubota K
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- Kulaga EV
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- Kumari BK
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- Kunze-Szikszay N
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- Kurth T
- Kurtz P
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- Kwon HM
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- Kye YC
- Kyle UG
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- Labaune MA
- Labra C
- Lacerda P
- Laerkner E
- Lafaurie M
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- Lagonidis D
- Lagos R
- Lahmer T
- Lai CC
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- Latini R
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- Lin KC
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- Lissonde F
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- Liu CP
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- Liu D
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- Llorente B
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- Lortat-Jacob B
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- Macrì M
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- Okayama Research Investigation Organizing Network (ORION)investigators
- Olaechea P
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- Song I
- Song JG
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- Song YG
- Sonneville R
- Sosa M
- Sossou A
- Sousa SC
- Soussi S
- Souza VA
- Spadaro S
- Spadaro S
- Spahn DR
- Spatenkova V
- Spazzadeschi A
- Spijkstra JJ
- Spronk PE
- Spronk PE
- Sprung CL
- St George’s University of London
- Stamm J
- Stamouli M
- Stanić R
- Starczewska M
- Staszewsky L
- Stauffert N
- Stella A
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- Stocchetti N
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- Stougianni M
- Street H
- Stretti F
- Struijs A
- Stubbs C
- Stubbs C
- Student Research Committee - Shiraz University of Medical Sciences
- Stümpfle R
- Stümpfle R
- Su F
- Su L
- Su PL
- Su PL
- Suchomel P
- Suh GJ
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- Suh GY
- Suh JW
- Sullivan E
- Sun WZ
- Sun XM
- Sung D
- Suwanpasu S
- Suzuki S
- Suzuki T
- Swart M
- Sy O
- Sydow K
- Sylla P
- Sáez VC
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- Sánchez PC
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- Tabatabaei HR
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- Taccone F
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- Taggu A
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- Takahashi H
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- Takeda M
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- Thabut G
- Thabut G
- Theodorakopoulou M
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- Thomas B
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- Tiainen M
- Timsit JF
- Tirkkonen J
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- Tokyo Womens Medical University
- Tomas E
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- Yilmazer F
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- Yoshida T
- Yoshida T
- Yoshihiro S
- Yoshitake E
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- Yumoto T
- Yuzawa J
- Yuzawa J
- Zabaletta WJ
- Zabini D
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
Meeting abstrac
The conundrum of iron in multiple sclerosis – time for an individualised approach
- Author
- A Alcina
- A Ascherio
- A Bettencourt
- A Ceccarelli
- A Jana
- A Miravalle
- AC Cepeda-Lopez
- AP Corthals
- AV Singh
- B Newman
- B Todorich
- B Todorich
- B Weinstock-Guttman
- BC Healy
- BD Trapp
- C Confavreux
- C Kaur
- C Lefebvre d'Hellencourt
- C Sfagos
- Cable RG Glynn SA, Kiss JE, Mast AE, Steele WR, Murphy EL, Wright DJ, Sacher RA, Gottschall JL, Vij V, Simon TL
- CC Ungley
- CW Adams
- CW Levenson
- D Baas
- D Pleasure
- D Voet
- DB Kell
- DJ Morath
- DJ Morath
- E Beutler
- E Byun
- E Elolf
- E Gray
- E Sundqvist
- EM Haacke
- EM Haacke
- EU Walther
- F Fink
- FD Lublin
- FS Collins
- G Filippini
- G Jong de
- G Logroscino
- G Logroscino
- G Poloni
- GC DeLuca
- GK Matsushima
- GM Liuzzi
- GP Owens
- GS Baldwin
- H Perron
- H Wekerle
- HA Arnett
- HM French
- HN Kirkman
- I Neveu
- I Nordvik
- I Steiner
- I Steiner
- J Doorduin
- J Fisher
- JA Reekers
- JC Dale
- JD Ly
- JF Kurtzke
- JP Rubio
- JR Connor
- JR Connor
- K Marder
- KL Munger
- KM Rodrigue
- LI Levin
- LM Hancock
- LR Caplan
- M Cau
- M Comabella
- M Filippi
- M Gazouli
- M Khalil
- M Koc
- M Rodriguez
- Maritha J. Kotze
- ME Badaracco
- MH Barnett
- MH Barnett
- MJ Kotze
- MJ Kotze
- MJ Kotze
- MJ Kotze
- MM Hiremath
- MR Gerber
- N Koning
- O Ates
- P Morell
- P Sundström
- P Suominen
- P Zamboni
- PA Krayenbuehl
- PO Behan
- R Hohlfeld
- R Schwartz
- R Surtees
- R Toorn van
- RC Axtell
- RN Rooney
- Ronald van Toorn
- RR Selzer
- S Fassl
- S Ilniczky
- S Kimball
- S Michaeli
- S Ristić
- S Sriram
- S Strasser-Fuchs
- SA Back
- SA Warren
- SE Baranzini
- SG Lynch
- SJ Pittock
- SJ Pittock
- SJ Rensburg van
- SJ Rensburg van
- SJ Rensburg van
- SM Grant
- SM LeVine
- Susan J. van Rensburg
- SV Ramagopalan
- SV Ramagopalan
- SV Ramagopalan
- SV Ramagopalan
- SV Ramagopalan
- SW Hulet
- T Ganz
- The International Multiple Sclerosis Genetics Consortium & the Wellcome Trust Case Control Consortium 2
- V Mastorodemos
- V Worthington
- W Cammer
- X Zhang
- Y Yang
- YS Kim
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Phytovolatilisation of organic chemicals (Series)
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Phytovolatilisation of organic chemicals
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Differences in uptake and translocation of selenate and selenite by the weeping willow and hybrid willow
- Author
- A Shrift
- A Zayed
- AM Zayed
- BG Lewis
- C Ciucani
- D Hansen
- DBD Simmons
- DR Ellis
- E Meers
- EC Duckart
- GS Banuelos
- GS Banuelos
- GS Banuelos
- I Rosenfeld
- J Schönherr
- Ji-Dong Gu
- JL Hopper
- L Sachs
- L Wu
- M Ihnat
- M Ike
- M Srivastava
- MP Avry
- MP Souza De
- N Terry
- N Terry
- N Terry
- S Trapp
- S Trapp
- SF Trelease
- SJ Hamilton
- TA Brown
- U Shardendu
- Xiao-Zhang Yu
- XZ Yu
- XZ Yu
- Y Zhang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
The uptake modeling of DDT and its degradation products (o,p′-DDE and p,p′-DDE) from soil
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Dielectric anisotropy of oven- and air-dried wood evaluated using a free space millimeter wave
- Author
- A Büchner
- A Laurinavičius
- AJ Nanassy
- AR Hippel Von
- DK Ghodgaonkar
- DK Ghodgaonkar
- E Peyskens
- GI Torgovnikov
- GS Schajer
- GS Schajer
- Hiroyoshi Togo
- I Makoviny
- J Johansson
- J Shen
- J-F Portala
- K Kröner
- K Kröner
- K Lichtenecker
- K Lichtenecker
- K Nakato
- L Hansson
- M Norimoto
- M Norimoto
- N Lundgren
- Naoya Kukutsu
- P Martin
- RJ King
- S Tanaka
- Shogo Okumura
- Shoji Mochizuki
- Soichi Tanaka
- T Uyemura
- T Zakri
- W Trapp
- W Trapp
- WL James
- Y Oyama
- Yoshihisa Fujii
- Yuko Fujiwara
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
- …