Comorbidities and Race/Ethnicity Among Adults with Stimulant Use Disorders in Residential Treatment

Comorbid physical and mental health problems are associated with poorer substance abuse treatment outcomes; however, little is known about these conditions among stimulant abusers at treatment entry. This study compared racial and ethnic groups on baseline measures of drug use patterns, comorbid physical and mental health disorders, quality of life, and daily functioning among cocaine and stimulant abusing/dependent patients. Baseline data from a multi-site randomized clinical trial of vigorous exercise as a treatment strategy for a diverse population of stimulant abusers (N = 290) were analyzed. Significant differences between groups were found on drug use characteristics, stimulant use disorders, and comorbid mental and physical health conditions. Findings highlight the importance of integrating health and mental health services into substance abuse treatment and could help identify potential areas for intervention to improve treatment outcomes for racial and ethnic minority groups

Solution to the problem of the poor cyclic fatigue resistance of bulk metallic glasses

The recent development of metallic glass-matrix composites represents a particular milestone in engineering materials for structural applications owing to their remarkable combination of strength and toughness. However, metallic glasses are highly susceptible to cyclic fatigue damage, and previous attempts to solve this problem have been largely disappointing. Here, we propose and demonstrate a microstructural design strategy to overcome this limitation by matching the microstructural length scales (of the second phase) to mechanical crack-length scales. Specifically, semisolid processing is used to optimize the volume fraction, morphology, and size of second-phase dendrites to confine any initial deformation (shear banding) to the glassy regions separating dendrite arms having length scales of ≈2 μm, i.e., to less than the critical crack size for failure. Confinement of the damage to such interdendritic regions results in enhancement of fatigue lifetimes and increases the fatigue limit by an order of magnitude, making these “designed” composites as resistant to fatigue damage as high-strength steels and aluminum alloys. These design strategies can be universally applied to any other metallic glass systems

Modeling Pitch Trajectories in Fastpitch Softball

The fourth-order Runge–Kutta method is used to numerically integrate the equations of motion for a fastpitch softball pitch and to create a model from which the trajectories of drop balls, rise balls and curve balls can be computed and displayed. By requiring these pitches to pass through the strike zone, and by assuming specific values for the initial speed, launch angle and height of each pitch, an upper limit on the lift coefficient can be predicted which agrees with experimental data. This approach also predicts the launch angles necessary to put rise balls, drop balls and curve balls in the strike zone, as well as a value of the drag coefficient that agrees with experimental data. Finally, Adair’s analysis of a batter’s swing is used to compare pitches that look similar to a batter starting her swing, yet which diverge before reaching the home plate, to predict when she is likely to miss or foul the ball

The Scaled Arrival of K-12 Online Education: Emerging Realities and Implications for the Future of Education

Bioinfo PublicationsDramatic increases in K—12 online education for all students, including those in traditionally underserved populations, necessi2 tate a reconceptualization in the way educators plan and implement instruction. In this article the authors examine the complex array of variables and implementation models that must be accounted for during the pivot from a purely brick-and-mortar educational sys2 tem to one that makes use of both virtual and blended environ2 ments. The authors call for enhanced emphasis on instructional goals and design principles, rather than the capabilities of available technology. They conclude that educational leaders and researchers must play a role in three key areas: using technology to enhance the accessibility and usability of curricular materials to meet the needs of different types of learners, advancing the understanding and practices of in-service and pre-service teachers through preparation that focuses on online learning, and fostering collaboration between educational researchers and technology innovators and developers to build a research base that will inform K—12 online education

Application of a Self-Similar Pressure Profile to Sunyaev-Zel'dovich Effect Data from Galaxy Clusters

We investigate the utility of a new, self-similar pressure profile for fitting Sunyaev-Zel'dovich (SZ) effect observations of galaxy clusters. Current SZ imaging instruments - such as the Sunyaev-Zel'dovich Array (SZA) - are capable of probing clusters over a large range in physical scale. A model is therefore required that can accurately describe a cluster's pressure profile over a broad range of radii, from the core of the cluster out to a significant fraction of the virial radius. In the analysis presented here, we fit a radial pressure profile derived from simulations and detailed X-ray analysis of relaxed clusters to SZA observations of three clusters with exceptionally high quality X-ray data: A1835, A1914, and CL J1226.9+3332. From the joint analysis of the SZ and X-ray data, we derive physical properties such as gas mass, total mass, gas fraction and the intrinsic, integrated Compton y-parameter. We find that parameters derived from the joint fit to the SZ and X-ray data agree well with a detailed, independent X-ray-only analysis of the same clusters. In particular, we find that, when combined with X-ray imaging data, this new pressure profile yields an independent electron radial temperature profile that is in good agreement with spectroscopic X-ray measurements.Comment: 28 pages, 6 figures, accepted by ApJ for publication (probably April 2009

Influence of melt feeding scheme and casting parameters during direct-chill casting on microstructure of an AA7050 billet

© The Minerals, Metals & Materials Society and ASM International 2012Direct-chill (DC) casting billets of an AA7050 alloy produced with different melt feeding schemes and casting speeds were examined in order to reveal the effect of these factors on the evolution of microstructure. Experimental results show that grain size is strongly influenced by the casting speed. In addition, the distribution of grain sizes across the billet diameter is mostly determined by melt feeding scheme. Grains tend to coarsen towards the center of a billet cast with the semi-horizontal melt feeding, while upon vertical melt feeding the minimum grain size was observed in the center of the billet. Computer simulations were preformed to reveal sump profiles and flow patterns during casting under different melt feeding schemes and casting speeds. The results show that solidification front and velocity distribution of the melt in the liquid and slurry zones are very different under different melt feeding scheme. The final grain structure and the grain size distribution in a DC casting billet is a result of a combination of fragmentation effects in the slurry zone and the cooling rate in the solidification range

Scotland, Catalonia and the “right” to self-determination: a comment suggested by Kathryn Crameri’s “Do Catalans Have the Right to Decide?

No abstract available

Anelastic deformation of a Pd40Cu30Ni10P20 bulk metallic glass during nanoindentation

This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics.Time-dependent deformation processes during nanoindentation have been investigated on a Pd40Cu30Ni10P20 bulk metallic glass. Deformation under constant load has been studied as a function of prior loading rate and temperature. The constant-load displacement of the indenter into the sample shows classic relaxation kinetics and reveals the importance of anelasticity for the mechanical behavior of metallic glasses at the nanoscale