2,469 research outputs found
Podiatry services for patients with arthritis: an unmet need
Foot problems are extremely common in patients with rheumatoid arthritis (RA).
There is ample evidence that foot pain, either alone or as a comorbidity, contributes
significantly to disability. Despite the high prevalence of foot disease in RA, this
problem is often trivialised or underappreciated. The inequity in foot health provision
for patients with rheumatic disorders in New Zealand has recently been highlighted.
Expertise in dealing with foot problems is often limited among healthcare
professionals, and it has been argued that better integration of podiatric services into
rheumatology services would be beneficial. The aim of this paper is to highlight the
major issues related to foot care for patients with arthritis and provide key
recommendations that should implemented to improve access to podiatric services in
New Zealand
Modeling charge transport in Swept Charge Devices for X-ray spectroscopy
We present the formulation of an analytical model which simulates charge
transport in Swept Charge Devices (SCDs) to understand the nature of the
spectral redistribution function (SRF). We attempt to construct the
energy-dependent and position dependent SRF by modeling the photon interaction,
charge cloud generation and various loss mechanisms viz., recombination,
partial charge collection and split events. The model will help in optimizing
event selection, maximize event recovery and improve spectral modeling for
Chandrayaan-2 (slated for launch in 2014). A proto-type physical model is
developed and the algorithm along with its results are discussed in this paper.Comment: 9 pages, 7 figures, Proc. SPIE 8453, High Energy, Optical, and
Infrared Detectors for Astronomy
Macrophage Migration Is Impaired within Candida albicans Biofilms
Acknowledgments: We thank the Microscopy and Histology Core Facility at the University of Aberdeen. This work was funded by NHS Grampian Endowments (grant RG10191); the Wellcome Trust Strategic Award in Medical Mycology and Fungal Immunology (grant 097377); the Wellcome Trust Investigator award (grants 101873, 086827, 075470, & 200208) and the Medical Research Council Centre for Medical Mycology (grant MR/N006364/1).Peer reviewedPublisher PD
Fluence and polarisation dependence of GaAs based Lateral Photo-Dember terahertz emitters
We characterise THz output of lateral photo-Dember (LPD) emitters based on semi-insulating (SI), unannealed and annealed low temperature grown (LTG) GaAs. Saturation of THz pulse power with optical fluence is observed, with unannealed LTG GaAs showing highest saturation fluence at 1.1 ± 0.1 mJ cm-2. SI-GaAs LPD emitters show a flip in signal polarity with optical fluence that is attributed to THz emission from the metal-semiconductor contact. Variation in optical polarisation affects THz pulse power that is attributed to a local optical excitation near the metal contact
Metabolism impacts upon Candida immunogenicity and pathogenicity at multiple levels
Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved. Open Access funded by Wellcome TrustNon peer reviewedPublisher PD
Hyphal growth of phagocytosed fusarium oxysporum causes cell lysis and death of murine macrophages
Peer reviewedPublisher PD
A dial-reading translator for digital machine inputs
At the Southern California Co-operative Wind Tunnel, part of the need for rapid and accurate recording of instrument readings on tabular data sheets has been met by the development of a new automatic-translating device. This device has unusually low torque and is especially suitable for use with self-balancing potentiometers. The device picks up the reading as a whole number and electrically transfers it to standard printing and punched-card machines, without lag and without restricting the normal operation of the potentiometer
Importance of charge capture in interphase regions during readout of charge-coupled devices
The current understanding of charge transfer dynamics in charge-coupled devices (CCDs) is that charge is moved so quickly from one phase to the next in a clocking sequence and with a density so low that trapping of charge in the interphase regions is negligible. However, simulation capabilities developed at the Centre for Electronic Imaging, which includes direct input of electron density simulations, have made it possible to investigate this assumption further. As part of the radiation testing campaign of the Euclid CCD273 devices, data have been obtained using the trap pumping method, a method that can be used to identify and characterize single defects within CCDs. Combining these data with simulations, we find that trapping during the transfer of charge among phases is indeed necessary to explain the results of the data analysis. This result could influence not only trap pumping theory and how trap pumping should be performed but also how a radiation-damaged CCD is readout in the most optimal way
Early-expressed chemokines predict kidney immunopathology in experimental disseminated Candida albicans infections
Available under the Creative Commons Attribution License (CCAL)Peer reviewedPublisher PD
Co-transport-induced instability of membrane voltage in tip-growing cells
A salient feature of stationary patterns in tip-growing cells is the key role
played by the symports and antiports, membrane proteins that translocate two
ionic species at the same time. It is shown that these co-transporters
destabilize generically the membrane voltage if the two translocated ions
diffuse differently and carry a charge of opposite (same) sign for symports
(antiports). Orders of magnitude obtained for the time and lengthscale are in
agreement with experiments. A weakly nonlinear analysis characterizes the
bifurcation
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