A practical biogas based energy neutral home system for rural communities of Bangladesh

Growing demand of energy consumption, subsequent increase in energy generation costs, and increased greenhouse gas(GHG) emissions, as well as global warming from the conventional energy sources, encourages interest worldwide to bring a higher percentage of renewable energy sources such as biogas into the energy mix to build a climate friendly environment for the future. Moreover, due to high investment and maintenance costs, governments are not providing enough support for grid extension and delivering electricity to remote locations or rural areas, in particular, in under-developing countries like Bangladesh. Therefore, this paper presents an Energy Neutral Home System (ENHS) that can meet all its energy requirements from low-cost, locally available, nonpolluting biogas generated from animal waste, in particular, chicken and cow manure. The proposed ENHS has been developed for rural community, typically an area of 200 families, and will not only provide cooking gas and sustainable and affordable power supply to the community with low emissions, but will also facilitate high quality fertilizer for agricultural purposes. In-depth analysis clearly demonstrates that the proposed ENHS not only offers electricity and cooking gas to the community with the lowest costs, but also reduces the energy crisis and GHG emissions and can play an active role in developing socio-economic infrastructure of rural communities in Bangladesh in many ways

Promoting agri-food systems resilience through ICT in developing countries amid COVID-19

An increasing body of literature has demonstrated COVID-19's harmful impact on agri-food systems, which are a major source of livelihood for millions of people worldwide. Information and communication technology (ICT) has been playing an increasing role in enhancing agri-food systems' resilience amid COVID-19. In this study, the PRISMA approach was employed to perform a systematic review of the literature from January 2020 to December 2021 on the overall impact of COVID-19 on agri-food system networks and ICT's role in enhancing agri-food system resilience in developing countries. This study reveals that COVID-19 has posed abundant obstacles to agri-food systems actors, including a lack of inputs, technical support, challenges to selling the product, transportation barriers, and low pricing. These impediments result in insufficient output, unforeseen stock, and revenue loss. COVID-19's restrictions have caused a significant food deficit by disrupting the demand and supply sides of the agri-food system networks. A high number of small-scale farmers have had to deal with food insecurity. As a result of the cumulative effects, actors in the agri-food system are getting less motivated to continue producing. This study also argues that many challenges in the agri-food systems can be overcome using ICTs, including maintaining precise farm management, product marketing, and access to production inputs. To assist stakeholders in coping with, adapting to, and building resilience in the agri-food system networks, this article emphasizes the critical need to turn to and expand the application of advanced agricultural ICTs to meet the world's growing needs for food production and to ensure the resilience and sustainability of farming systems, particularly in the face of a pandemic like COVID-19

NRF2-driven miR-125B1 and miR-29B1 transcriptional regulation controls a novel anti-apoptotic miRNA regulatory network for AML survival

Transcription factor NRF2 is an important regulator of oxidative stress. It is involved in cancer progression, and has abnormal constitutive expression in acute myeloid leukaemia (AML). Posttranscriptional regulation by microRNAs (miRNAs) can affect the malignant phenotype of AML cells. In this study, we identified and characterised NRF2-regulated miRNAs in AML. An miRNA array identified miRNA expression level changes in response to NRF2 knockdown in AML cells. Further analysis of miRNAs concomitantly regulated by knockdown of the NRF2 inhibitor KEAP1 revealed the major candidate NRF2-mediated miRNAs in AML. We identified miR-125B to be upregulated and miR-29B to be downregulated by NRF2 in AML. Subsequent bioinformatic analysis identified putative NRF2 binding sites upstream of the miR-125B1 coding region and downstream of the mir-29B1 coding region. Chromatin immunoprecipitation analyses showed that NRF2 binds to these antioxidant response elements (AREs) located in the 5′ untranslated regions of miR-125B and miR-29B. Finally, primary AML samples transfected with anti-miR-125B antagomiR or miR-29B mimic showed increased cell death responsiveness either alone or co-treated with standard AML chemotherapy. In summary, we find that NRF2 regulation of miR-125B and miR-29B acts to promote leukaemic cell survival, and their manipulation enhances AML responsiveness towards cytotoxic chemotherapeutics

Understanding the socio-economic impacts of climate change on riparian communities in Bangladesh

Riparian communities in developing countries such as Bangladesh, whose livelihoods depend especially on fisheries and other subsistence activities, are under considerable pressure due to climate change. Therefore, there is a need to better understand how the dynamics of riparian communities are influenced by climate change and how its impacts can be assessed. Using Bangladesh as an example, this paper describes the various climate stressors affecting riparian communities and their socio-economic impacts, and it outlines some measures needed to increase their resilience to a changing climate. The results show that riparian communities are not only quite vulnerable to the impacts of climate change but also have a rather low level of resilience. This challenge can, at least in part, be attributed to their fragile living conditions, which intensify the socio-economic impacts of extreme events. One lesson from the paper is that handling climate-induced risks in riparian communities requires implementing strategic measures to improve local climate and livelihood resilience, such as effective public health infrastructure and a resilient built environment. Win-win scenarios comprise strategies that offer multiple benefits including better water storage, flood control, and improved riparian habitats

The Universal One-Loop Effective Action

We present the universal one-loop effective action for all operators of dimension up to six obtained by integrating out massive, non-degenerate multiplets. Our general expression may be applied to loops of heavy fermions or bosons, and has been checked against partial results available in the literature. The broad applicability of this approach simplifies one-loop matching from an ultraviolet model to a lower-energy effective field theory (EFT), a procedure which is now reduced to the evaluation of a combination of matrices in our universal expression, without any loop integrals to evaluate. We illustrate the relationship of our results to the Standard Model (SM) EFT, using as an example the supersymmetric stop and sbottom squark Lagrangian and extracting from our universal expression the Wilson coefficients of dimension-six operators composed of SM fields.Comment: 30 pages, v2 contains additional comments and corrects typos, version accepted for publication in JHE

Sustainability practices at higher education institutions in Asia

Purpose: It is still unclear how Asian universities incorporate the theory or practice of sustainable development (SD) in their research and education programmes. To address this gap, the purpose of this paper is to report on a study that has examined how universities in Asian countries handle and address matters related to SD. Design/methodology/approach: The study used a bibliometric analysis and an online survey-method. The online survey data were analysed through descriptive analysis and one-sample student’s t-test. Findings: The study indicates that there is considerable variation among the Asian countries regarding sustainability practices in higher education institutions (HEIs). The HEIs in far eastern countries, such as Indonesia, Malaysia and Thailand are perceived to demonstrate more sustainability practices. Research limitations/implications: Even though a substantial number of participants participated in the survey, it did not cover all Asian countries. The online survey was carried out over a limited period of time, and not all HEIs in the field may have received information about the study. Practical implications: Asia is the largest continent facing a number of sustainability challenges. In this context, the contribution of HEIs is very important. The findings of the current study may serve as a baseline for Asian HEIs to take more initiatives towards SD goals, as HEIs are responsible for the education and training of hundreds of thousands of students who will be occupying key positions in industry, government or education in the coming years. Originality/value: The study contributes to the existing literature in two distinct ways. First, it was possible to develop a comprehensive instrument to measure sustainability practices in HEIs. Second, this study has filled the gap of the scarcity of studies regarding sustainability practices in HEIs in Asia

RESEARCH AND REVIEWS: JOURNAL OF MATERIAL SCIENCES Renewable Okra Bast Fiber Reinforced Phenol Formaldehyde Resin Composites: Mechanical and Thermal Studies

ABSTRACT Okra bast fiber (OBF) reinforced thermoset phenol formaldehyde (PF) resin composites were prepared by compression molding methods. In order to found better wetting of filler and matrix, OBF was treated with NaOH. The properties of composites were studied by mechanical tests, thermal methods and water uptake. The mechanical properties such as tensile strength (TS), Young's modulus (YM), tensile elongation, flexural strength (FS) and flexural modulus of composites were varied with NaOH concentration, treatment time and fiber loading. TS and FS were found to increase for fiber loading upto 30% and then decreased whereas YM, FM and tensile elongation were increased with increase of weight fraction. About 21% more TS and 85% more FS was found for 10% alkali treated fiber composite than untreated fiber composite. Treated fiber composites also showed greater thermal stability and lower water absorption property

Biopsy-based calibration of T2* magnetic resonance for estimation of liver iron concentration and comparison with R2 Ferriscan.

BACKGROUND: There is a need to standardise non-invasive measurements of liver iron concentrations (LIC) so clear inferences can be drawn about body iron levels that are associated with hepatic and extra-hepatic complications of iron overload. Since the first demonstration of an inverse relationship between biopsy LIC and liver magnetic resonance (MR) using a proof-of-concept T2* sequence, MR technology has advanced dramatically with a shorter minimum echo-time, closer inter-echo spacing and constant repetition time. These important advances allow more accurate calculation of liver T2* especially in patients with high LIC. METHODS: Here, we used an optimised liver T2* sequence calibrated against 50 liver biopsy samples on 25 patients with transfusional haemosiderosis using ordinary least squares linear regression, and assessed the method reproducibility in 96 scans over an LIC range up to 42 mg/g dry weight (dw) using Bland-Altman plots. Using mixed model linear regression we compared the new T2*-LIC with R2-LIC (Ferriscan) on 92 scans in 54 patients with transfusional haemosiderosis and examined method agreement using Bland-Altman approach. RESULTS: Strong linear correlation between ln(T2*) and ln(LIC) led to the calibration equation LIC = 31.94(T2*)-1.014. This yielded LIC values approximately 2.2 times higher than the proof-of-concept T2* method. Comparing this new T2*-LIC with the R2-LIC (Ferriscan) technique in 92 scans, we observed a close relationship between the two methods for values up to 10 mg/g dw, however the method agreement was poor. CONCLUSIONS: New calibration of T2* against liver biopsy estimates LIC in a reproducible way, correcting the proof-of-concept calibration by 2.2 times. Due to poor agreement, both methods should be used separately to diagnose or rule out liver iron overload in patients with increased ferritin