501 research outputs found
Intrinsic modulation of pulse-coupled integrate-and-fire neurons
Intrinsic neuromodulation is observed in sensory and neuromuscular circuits and in biological central pattern generators. We model a simple neuronal circuit with a system of two pulse-coupled integrate-and-fire neurons and explore the parameter regimes for periodic firing behavior. The inclusion of biologically realistic features shows that the speed and onset of neuronal response plays a crucial role in determining the firing phase for periodic rhythms. We explore the neurophysiological function of distributed delays arising from both the synaptic transmission process and dendritic structure as well as discrete delays associated with axonal communication delays. Bifurcation and stability diagrams are constructed with a mixture of simple analysis, numerical continuation and the Kuramoto phase-reduction technique. Moreover, we show that, for asynchronous behavior, the strength of electrical synapses can control the firing rate of the system
A weighted reduced basis method for parabolic PDEs with random data
This work considers a weighted POD-greedy method to estimate statistical
outputs parabolic PDE problems with parametrized random data. The key idea of
weighted reduced basis methods is to weight the parameter-dependent error
estimate according to a probability measure in the set-up of the reduced space.
The error of stochastic finite element solutions is usually measured in a root
mean square sense regarding their dependence on the stochastic input
parameters. An orthogonal projection of a snapshot set onto a corresponding POD
basis defines an optimum reduced approximation in terms of a Monte Carlo
discretization of the root mean square error. The errors of a weighted
POD-greedy Galerkin solution are compared against an orthogonal projection of
the underlying snapshots onto a POD basis for a numerical example involving
thermal conduction. In particular, it is assessed whether a weighted POD-greedy
solutions is able to come significantly closer to the optimum than a
non-weighted equivalent. Additionally, the performance of a weighted POD-greedy
Galerkin solution is considered with respect to the mean absolute error of an
adjoint-corrected functional of the reduced solution.Comment: 15 pages, 4 figure
A Dimension-Adaptive Multi-Index Monte Carlo Method Applied to a Model of a Heat Exchanger
We present an adaptive version of the Multi-Index Monte Carlo method,
introduced by Haji-Ali, Nobile and Tempone (2016), for simulating PDEs with
coefficients that are random fields. A classical technique for sampling from
these random fields is the Karhunen-Lo\`eve expansion. Our adaptive algorithm
is based on the adaptive algorithm used in sparse grid cubature as introduced
by Gerstner and Griebel (2003), and automatically chooses the number of terms
needed in this expansion, as well as the required spatial discretizations of
the PDE model. We apply the method to a simplified model of a heat exchanger
with random insulator material, where the stochastic characteristics are
modeled as a lognormal random field, and we show consistent computational
savings
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