Receipt from Benj. Gillespie

https://digitalcommons.salve.edu/goelet-new-york/1244/thumbnail.jp

Receipt from Benj. Gillespie to P. McCormick and Receipt from Peter McCormick to Ogden Goelet

https://digitalcommons.salve.edu/goelet-new-york/1013/thumbnail.jp

CLAGS Events and Outreach, Spring 2013

This past semester, CLAGS held many successful and provocative events that effectively supported our mandate as a platform for historical and contemporary issues affecting the LGBTQ community. We hosted the book launch for Born This Way: Real Stories of Growing up Gay by Paul Vitigliano, featuring such guest speakers as Noah Michelson (Huffington Post Gay Voices) and Michael Musto (Columnist, Village Voice)

Performing Que(e)ries: Nina Arsenault with J. Paul Halferty

This exciting conversation and performance demo with one of Canada’s leading queer performance artists took place on October 26th, 2012 in the Segal Theatre at the CUNY Graduate Center. The event featured two short films made by Arsenault and filmmaker Jordan Tannehill, Plane of Immanence and Guadalajara, as well as an extended monologue by Arsenault retelling an autobiographical story on her quest for feminine beauty entitled The Ecstasy of Nina Arsenault: a surgical pilgrimage through a waking facelift

A model for simulating dynamic problems of economic development

At head of title: Economic dynamics"July 1960."Includes bibliographic references (p. 198-203

Impacts of flow regulation and Artificial Floods in an upland stream ecosystem

Mitigation of ecological impacts associated with stream regulation is now a legislative priority and Artificial Floods have been suggested as a potential tool to achieve this aim. However, understanding of the impacts of stream regulation and Artificial Floods on downstream ecology is currently limited. This thesis provides detailed reviews of both of these topics and identifies key contemporary research priorities. These priorities were subsequently addressed through assessment of the impact of stream regulation and Artificial Floods on downstream hydrology, physical chemistry, coarse sediment transport and benthic macroinvertebrates in an upland subcatchment of the River Humber, UK. Evidence that regulation was associated with significant impacts on hydrology (e.g. flood frequency, rate of change), physical chemistry (particularly flood pH and diurnal stream temperature range) and macroinvertebrates was identified, but impacts were found to vary spatially and temporally, indicating the importance of site specific and temporal factors. Control of hydrological characteristics was demonstrated during Artificial Floods which generally resulted in reductions of electrical conductivity, dissolved oxygen and pH and no change in stream temperature. Evidence for coarse sediment transport in line with overspill events prior to Artificial Floods was identified, but little evidence for change in macroinvertebrate assemblage was found. Evidence for the use of Artificial Floods as a management tool was greatest for coarse sediment transport and pH but overall, limited potential was demonstrated, bringing into question their validity as management techniques in some regulated streams and provoking requirement for further research. The findings of this thesis, methodological developments, conceptual advances and recommendations are therefore considered to have advanced the science and understanding of regulated stream management. Such progress is vital in this rapidly developing research field

Global analysis of carbon disulfide (CS2) using the 3-D chemistry transport model STOCHEM

Carbon disulfide (CS₂), a precursor to the long-lived carbonyl sulphide (OCS) is one of the main contributors to the atmospheric sulfate layer. The annual fluxes from its sources and sinks are investigated using a 3-D chemistry transport model, STOCHEM-CRI. In terms of the flux analysis, the oxidation of CS₂ by OH is found to be the main removal process (76–88% of the total loss) and the dry deposition loss contributes 11–24% to the total loss of CS₂. The global burden of CS₂ was calculated, varying between 6.1 to 19.2 Tg and the lifetime of CS₂was determined to be within the range of 2.8–3.4 days. The global distribution of CS₂ found the Northern Hemisphere (NH) continental landmasses to be the areas of concentration maxima with peak concentrations reaching up to 20 ppt during June-July-August (J-J-A) season and 40 ppt during December-January-February (D-J-F) season in anthropogenic source regions. Oceanic regions returned low CS₂ levels of less than 2 ppt. The vertical profile of CS₂ shows higher levels up to 3 ppt at 30°N–45°N during J-J-A and up to 4 ppt at 30°N–55°N during D-J-F. The oxidation of CS₂by OH can produce a substantial amount (0.58 Tg/yr) of atmospheric OCS and the annual average surface distribution of this flux shows up to 6 Gg/yr OCS formed in the regions with highest anthropogenic pollution (e.g., South east Asia). In general, the model-measurement comparison reveals an underprediction of model CS₂ compared with measured CS₂ for most of the regions. It is likely that the emissions of CS₂ are being underestimated and there are likely much larger emission sources of atmospheric CS₂ than previously suggested

Rapid determination of antimicrobial susceptibility of Gram-negative bacteria from clinical blood cultures using a scattered light integrated collection (SLIC) device

Funding: This work was funded by the University of St Andrews.Background A bloodstream infection (BSI) presents a complex and serious health problem, a problem that is being exacer- bated by increasing antimicrobial resistance (AMR). Gap statement The current turnaround times (TATs) for most antimicrobial susceptibility testing (AST) methods offer results retrospective of treatment decisions, and this limits the impact AST can have on antibiotic prescribing and patient care. Progress must be made towards rapid BSI diagnosis and AST to improve antimicrobial stewardship and reduce preventable deaths from BSIs. To support the successful implementation of rapid AST (rAST) in hospital settings, a rAST method that is affordable, is sustainable and offers comprehensive AMR detection is needed. Aim To evaluate a scattered light-integrated collection (SLIC) device against standard of care (SOC) to determine whether SLIC could accelerate the current TATs with actionable, accurate rAST results for Gram-negative BSIs. Methods Positive blood cultures from a tertiary referral hospital were studied prospectively. Flagged positive Gram-negative blood cultures were confirmed by Gram staining and analysed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, Vitek 2, disc diffusion (ceftriaxone susceptibility only) and an SLIC device. Susceptibility to a panel of five antibiotics, as defined by European Committee on Antimicrobial Susceptibility Testing breakpoints, was examined using SLIC. Results A total of 505 bacterial–antimicrobial combinations were analysed. A categorical agreement of 95.5 % (482/505) was achieved between SLIC and SOC. The 23 discrepancies that occurred were further investigated by the broth microdilution method, with 10 AST results in agreement with SLIC and 13 in agreement with SOC. The mean time for AST was 10.53±0.46 h and 1.94±0.02 h for Vitek 2 and SLIC, respectively. SLIC saved 23.96±1.47 h from positive blood culture to AST result. Conclusion SLIC has the capacity to provide accurate AST 1 day earlier from flagged positive blood cultures than SOC. This significant time saving could accelerate time to optimal antimicrobial therapy, improving antimicrobial stewardship and man- agement of BSIs.Peer reviewe

Rapid determination of antimicrobial susceptibility of Gram-negative bacteria from clinical blood cultures using a scattered light-integrated collection device

Background. A bloodstream infection (BSI) presents a complex and serious health problem, a problem that is being exacerbated by increasing antimicrobial resistance (AMR). Gap Statement. The current turnaround times (TATs) for most antimicrobial susceptibility testing (AST) methods offer results retrospective of treatment decisions, and this limits the impact AST can have on antibiotic prescribing and patient care. Progress must be made towards rapid BSI diagnosis and AST to improve antimicrobial stewardship and reduce preventable deaths from BSIs. To support the successful implementation of rapid AST (rAST) in hospital settings, a rAST method that is affordable, is sustainable and offers comprehensive AMR detection is needed. Aim. To evaluate a scattered light-integrated collection (SLIC) device against standard of care (SOC) to determine whether SLIC could accelerate the current TATs with actionable, accurate rAST results for Gram-negative BSIs. Methods. Positive blood cultures from a tertiary referral hospital were studied prospectively. Flagged positive Gram-negative blood cultures were confirmed by Gram staining and analysed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, Vitek 2, disc diffusion (ceftriaxone susceptibility only) and an SLIC device. Susceptibility to a panel of five antibiotics, as defined by European Committee on Antimicrobial Susceptibility Testing breakpoints, was examined using SLIC. Results. A total of 505 bacterial-antimicrobial combinations were analysed. A categorical agreement of 95.5% (482/505) was achieved between SLIC and SOC. The 23 discrepancies that occurred were further investigated by the broth microdilution method, with 10 AST results in agreement with SLIC and 13 in agreement with SOC. The mean time for AST was 10.53±0.46 h and 1.94±0.02 h for Vitek 2 and SLIC, respectively. SLIC saved 23.96±1.47 h from positive blood culture to AST result. Conclusion. SLIC has the capacity to provide accurate AST 1 day earlier from flagged positive blood cultures than SOC. This significant time saving could accelerate time to optimal antimicrobial therapy, improving antimicrobial stewardship and management of BSIs.</p