1,702 research outputs found
Polarization mode coupling and related effects in fiber Bragg grating inscribed in polarization maintaining fiber
©2016 Optical Society of America. Polarization mode coupling (PMC) and related effects from writing fiber Bragg gratings in polarization maintaining fiber (FBGs-in- PMF) are observed experimentally for the first time by optical fiber coherence domain polarimetry (OCDP) using a broadband light source. PMC is another useful aspect of FBG-in-PMF besides Bragg wavelength and its possible potential is evaluated and discussed. A localized and long range temperature measurement based on the PMC and Bragg wavelength is given as an example
Search for the Elusive Higgs Boson Using Jet Structure at LHC
We consider the production of a light non-standard model Higgs boson of order
100~\GEV with an associated boson at CERN Large Hadron Collider. We focus
on an interesting scenario that, the Higgs boson decays predominately into two
light scalars with mass of few GeV which sequently decay into four
gluons, i.e. . Since is much lighter than the Higgs
boson, it will be highly boosted and its decay products, the two gluons, will
move close to each other, resulting in a single jet for decay in the
detector. By using electromagnetic calorimeter-based and jet substructure
analyses, we show in two cases of different masses that it is quite
promising to extract the signal of Higgs boson out of large QCD background.Comment: 20 pages, 7 figure
Some Field Theoretic Issues Regarding the Chiral Magnetic Effect
In this paper, we shall address some field theoretic issues regarding the
chiral magnetic effect. The general structure of the magnetic current
consistent with the electromagnetic gauge invariance is obtained and the impact
of the infrared divergence is examined. Some subtleties on the relation between
the chiral magnetic effect and the axial anomaly are clarified through a
careful examination of the infrared limit of the relevant thermal diagrams.Comment: 19 pages, 4 figures in Latex. Typos fixed, version accepted to be
published in JHE
Nanoscale phase-engineering of thermal transport with a Josephson heat modulator
Macroscopic quantum phase coherence has one of its pivotal expressions in the
Josephson effect [1], which manifests itself both in charge [2] and energy
transport [3-5]. The ability to master the amount of heat transferred through
two tunnel-coupled superconductors by tuning their phase difference is the core
of coherent caloritronics [4-6], and is expected to be a key tool in a number
of nanoscience fields, including solid state cooling [7], thermal isolation [8,
9], radiation detection [7], quantum information [10, 11] and thermal logic
[12]. Here we show the realization of the first balanced Josephson heat
modulator [13] designed to offer full control at the nanoscale over the
phase-coherent component of thermal currents. Our device provides
magnetic-flux-dependent temperature modulations up to 40 mK in amplitude with a
maximum of the flux-to-temperature transfer coefficient reaching 200 mK per
flux quantum at a bath temperature of 25 mK. Foremost, it demonstrates the
exact correspondence in the phase-engineering of charge and heat currents,
breaking ground for advanced caloritronic nanodevices such as thermal splitters
[14], heat pumps [15] and time-dependent electronic engines [16-19].Comment: 6+ pages, 4 color figure
Privacy in crowdsourcing:a systematic review
The advent of crowdsourcing has brought with it multiple privacy challenges. For example, essential monitoring activities, while necessary and unavoidable, also potentially compromise contributor privacy. We conducted an extensive literature review of the research related to the privacy aspects of crowdsourcing. Our investigation revealed interesting gender differences and also differences in terms of individual perceptions. We conclude by suggesting a number of future research directions.</p
A weak characterization of slow variables in stochastic dynamical systems
We present a novel characterization of slow variables for continuous Markov
processes that provably preserve the slow timescales. These slow variables are
known as reaction coordinates in molecular dynamical applications, where they
play a key role in system analysis and coarse graining. The defining
characteristics of these slow variables is that they parametrize a so-called
transition manifold, a low-dimensional manifold in a certain density function
space that emerges with progressive equilibration of the system's fast
variables. The existence of said manifold was previously predicted for certain
classes of metastable and slow-fast systems. However, in the original work, the
existence of the manifold hinges on the pointwise convergence of the system's
transition density functions towards it. We show in this work that a
convergence in average with respect to the system's stationary measure is
sufficient to yield reaction coordinates with the same key qualities. This
allows one to accurately predict the timescale preservation in systems where
the old theory is not applicable or would give overly pessimistic results.
Moreover, the new characterization is still constructive, in that it allows for
the algorithmic identification of a good slow variable. The improved
characterization, the error prediction and the variable construction are
demonstrated by a small metastable system
Electronic Origin of High Temperature Superconductivity in Single-Layer FeSe Superconductor
The latest discovery of high temperature superconductivity signature in
single-layer FeSe is significant because it is possible to break the
superconducting critical temperature ceiling (maximum Tc~55 K) that has been
stagnant since the discovery of Fe-based superconductivity in 2008. It also
blows the superconductivity community by surprise because such a high Tc is
unexpected in FeSe system with the bulk FeSe exhibiting a Tc at only 8 K at
ambient pressure which can be enhanced to 38 K under high pressure. The Tc is
still unusually high even considering the newly-discovered intercalated FeSe
system A_xFe_{2-y}Se_2 (A=K, Cs, Rb and Tl) with a Tc at 32 K at ambient
pressure and possible Tc near 48 K under high pressure. Particularly
interesting is that such a high temperature superconductivity occurs in a
single-layer FeSe system that is considered as a key building block of the
Fe-based superconductors. Understanding the origin of high temperature
superconductivity in such a strictly two-dimensional FeSe system is crucial to
understanding the superconductivity mechanism in Fe-based superconductors in
particular, and providing key insights on how to achieve high temperature
superconductivity in general. Here we report distinct electronic structure
associated with the single-layer FeSe superconductor. Its Fermi surface
topology is different from other Fe-based superconductors; it consists only of
electron pockets near the zone corner without indication of any Fermi surface
around the zone center. Our observation of large and nearly isotropic
superconducting gap in this strictly two-dimensional system rules out existence
of node in the superconducting gap. These results have provided an unambiguous
case that such a unique electronic structure is favorable for realizing high
temperature superconductivity
Inhibition of the tyrosine phosphatase SHP-2 suppresses angiogenesis in vitro and in vivo
Endothelial cell survival is indispensable to maintain endothelial integrity and initiate new vessel formation. We investigated the role of SHP-2 in endothelial cell survival and angiogenesis in vitro as well as in vivo. SHP-2 function in cultured human umbilical vein and human dermal microvascular endothelial cells was inhibited by either silencing the protein expression with antisense-oligodesoxynucleotides or treatment with a pharmacological inhibitor (PtpI IV). SHP-2 inhibition impaired capillary-like structure formation (p < 0.01; n = 8) in vitro as well as new vessel growth ex vivo (p < 0.05; n = 10) and in vivo in the chicken chorioallantoic membrane (p < 0.01, n = 4). Additionally, SHP-2 knock-down abrogated fibroblast growth factor 2 (FGF-2)-dependent endothelial proliferation measured by MTT reduction ( p ! 0.01; n = 12). The inhibitory effect of SHP-2 knock-down on vessel growth was mediated by increased endothelial apoptosis ( annexin V staining, p ! 0.05, n = 9), which was associated with reduced FGF-2-induced phosphorylation of phosphatidylinositol 3-kinase (PI3-K), Akt and extracellular regulated kinase 1/2 (ERK1/2) and involved diminished ERK1/2 phosphorylation after PI3-K inhibition (n=3). These results suggest that SHP-2 regulates endothelial cell survival through PI3-K-Akt and mitogen-activated protein kinase pathways thereby strongly affecting new vessel formation. Thus, SHP-2 exhibits a pivotal role in angiogenesis and may represent an interesting target for therapeutic approaches controlling vessel growth. Copyright (C) 2007 S. Karger AG, Basel
A Large Double-ring Disk Around the Taurus M Dwarf J04124068+2438157
Planet formation imprints signatures on the physical structures of disks. In this paper, we present high-resolution (∼50 mas, 8 au) Atacama Large Millimeter/submillimeter Array observations of 1.3 mm dust continuum and CO line emission toward the disk around the M3.5 star 2MASS J04124068+2438157. The dust disk consists of only two narrow rings at radial distances of 0.″47 and 0.″78 (∼70 and 116 au), with Gaussian σ widths of 5.6 and 8.5 au, respectively. The width of the outer ring is smaller than the estimated pressure scale height by ∼25%, suggesting dust trapping in a radial pressure bump. The dust disk size, set by the location of the outermost ring, is significantly larger (by 3σ) than other disks with similar millimeter luminosity, which can be explained by an early formation of local pressure bump to stop radial drift of millimeter dust grains. After considering the disk’s physical structure and accretion properties, we prefer planet-disk interaction over dead zone or photoevaporation models to explain the observed dust disk morphology. We carry out high-contrast imaging at the L ′ band using Keck/NIRC2 to search for potential young planets, but do not identify any source above 5σ. Within the dust gap between the two rings, we reach a contrast level of ∼7 mag, constraining the possible planet below ∼2-4 M Jup. Analyses of the gap/ring properties suggest that an approximately Saturn-mass planet at ∼90 au is likely responsible for the formation of the outer ring, which can potentially be revealed with JWST
Coxiella burnetii Phagocytosis Is Regulated by GTPases of the Rho Family and the RhoA Effectors mDia1 and ROCK
The GTPases belonging to the Rho family control the actin cytoskeleton rearrangements needed for particle internalization during phagocytosis. ROCK and mDia1 are downstream effectors of RhoA, a GTPase involved in that process. Coxiella burnetii, the etiologic agent of Q fever, is internalized by the host´s cells in an actin-dependent manner. Nevertheless, the molecular mechanism involved in this process has been poorly characterized. This work analyzes the role of different GTPases of the Rho family and some downstream effectors in the internalization of C. burnetii by phagocytic and non-phagocytic cells. The internalization of C. burnetii into HeLa and RAW cells was significantly inhibited when the cells were treated with Clostridium difficile Toxin B which irreversibly inactivates members of the Rho family. In addition, the internalization was reduced in HeLa cells that overexpressed the dominant negative mutants of RhoA, Rac1 or Cdc42 or that were knocked down for the Rho GTPases. The pharmacological inhibition or the knocking down of ROCK diminished bacterium internalization. Moreover, C. burnetii was less efficiently internalized in HeLa cells overexpressing mDia1-N1, a dominant negative mutant of mDia1, while the overexpression of the constitutively active mutant mDia1-ΔN3 increased bacteria uptake. Interestingly, when HeLa and RAW cells were infected, RhoA, Rac1 and mDia1 were recruited to membrane cell fractions. Our results suggest that the GTPases of the Rho family play an important role in C. burnetii phagocytosis in both HeLa and RAW cells. Additionally, we present evidence that ROCK and mDia1, which are downstream effectors of RhoA, are involved in that processFil: Salinas Ojeda, Romina Paola. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Centro CientÃfico Tecnológico Conicet - Mendoza. Instituto de HistologÃa y EmbriologÃa de Mendoza Dr. Mario H. Burgos. Universidad Nacional de Cuyo. Facultad de Cienicas Médicas. Instituto de HistologÃa y EmbriologÃa de Mendoza Dr. Mario H. Burgos; ArgentinaFil: Ortiz Flores, Rodolfo Matias. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Centro CientÃfico Tecnológico Conicet - Mendoza. Instituto de HistologÃa y EmbriologÃa de Mendoza Dr. Mario H. Burgos. Universidad Nacional de Cuyo. Facultad de Cienicas Médicas. Instituto de HistologÃa y EmbriologÃa de Mendoza Dr. Mario H. Burgos; ArgentinaFil: Distel, Jesús Sebastián. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Centro CientÃfico Tecnológico Conicet - Mendoza. Instituto de HistologÃa y EmbriologÃa de Mendoza Dr. Mario H. Burgos. Universidad Nacional de Cuyo. Facultad de Cienicas Médicas. Instituto de HistologÃa y EmbriologÃa de Mendoza Dr. Mario H. Burgos; ArgentinaFil: Aguilera, Milton Osmar. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Centro CientÃfico Tecnológico Conicet - Mendoza. Instituto de HistologÃa y EmbriologÃa de Mendoza Dr. Mario H. Burgos. Universidad Nacional de Cuyo. Facultad de Cienicas Médicas. Instituto de HistologÃa y EmbriologÃa de Mendoza Dr. Mario H. Burgos; ArgentinaFil: Colombo, Maria Isabel. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Centro CientÃfico Tecnológico Conicet - Mendoza. Instituto de HistologÃa y EmbriologÃa de Mendoza Dr. Mario H. Burgos. Universidad Nacional de Cuyo. Facultad de Cienicas Médicas. Instituto de HistologÃa y EmbriologÃa de Mendoza Dr. Mario H. Burgos; ArgentinaFil: Beron, Walter. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Centro CientÃfico Tecnológico Conicet - Mendoza. Instituto de HistologÃa y EmbriologÃa de Mendoza Dr. Mario H. Burgos. Universidad Nacional de Cuyo. Facultad de Cienicas Médicas. Instituto de HistologÃa y EmbriologÃa de Mendoza Dr. Mario H. Burgos; Argentin
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