Laplacian Fractal Growth in Media with Quenched Disorder

We analyze the combined effect of a Laplacian field and quenched disorder for the generation of fractal structures with a study, both numerical and theoretical, of the quenched dielectric breakdown model (QDBM). The growth dynamics is shown to evolve from the avalanches of invasion percolation (IP) to the smooth growth of Laplacian fractals, i. e. diffusion limited aggregation (DLA) and the dielectric breakdown model (DBM). The fractal dimension is strongly reduced with respect to both DBM and IP, due to the combined effect of memory and field screening. This implies a specific relation between the fractal dimension of the breakdown structures (dielectric or mechanical) and the microscopic properties of disordered materials.Comment: 11 pages Latex (revtex), 3 postscript figures included. Submitted to PR

A dynamical classification of the range of pair interactions

We formalize a classification of pair interactions based on the convergence properties of the {\it forces} acting on particles as a function of system size. We do so by considering the behavior of the probability distribution function (PDF) P(F) of the force field F in a particle distribution in the limit that the size of the system is taken to infinity at constant particle density, i.e., in the "usual" thermodynamic limit. For a pair interaction potential V(r) with V(r) \rightarrow \infty) \sim 1/r^a defining a {\it bounded} pair force, we show that P(F) converges continuously to a well-defined and rapidly decreasing PDF if and only if the {\it pair force} is absolutely integrable, i.e., for a > d-1, where d is the spatial dimension. We refer to this case as {\it dynamically short-range}, because the dominant contribution to the force on a typical particle in this limit arises from particles in a finite neighborhood around it. For the {\it dynamically long-range} case, i.e., a \leq d-1, on the other hand, the dominant contribution to the force comes from the mean field due to the bulk, which becomes undefined in this limit. We discuss also how, for a \leq d-1 (and notably, for the case of gravity, a=d-2) P(F) may, in some cases, be defined in a weaker sense. This involves a regularization of the force summation which is generalization of the procedure employed to define gravitational forces in an infinite static homogeneous universe. We explain that the relevant classification in this context is, however, that which divides pair forces with a > d-2 (or a < d-2), for which the PDF of the {\it difference in forces} is defined (or not defined) in the infinite system limit, without any regularization. In the former case dynamics can, as for the (marginal) case of gravity, be defined consistently in an infinite uniform system.Comment: 12 pages, 1 figure; significantly shortened and focussed, additional references, version to appear in J. Stat. Phy

Chargino Contributions in B→ϕKSB \to \phi K_S Asymmetry

CP asymmetry in $B \to \phi K_S$ decay is studied in a special context of supersymmetry theories, in which the charginos play an important role. We find that in addition to the gluino, chargino can also make large contributions to CP asymmetry in $B \to \phi K_S$ decay. After considering the constraints from $B \to J/psi K_S$ decay, we study three special scenarios: (a). Large mixing on left-handed charm and top squarks (LL mixing); (b). Large mixing on right-handed charm and top squarks (RR mixing); (c). Large mixing on left-handed charm and top squarks plus right-handed charm and top squarks (LL + RR mixing). We show quantitatively that because of large squark mixing within second and third generations, an $\mathcal O$(1) effect on CP violation in $B \to \phi K_S$ is possible

Gravitational force distribution in fractal structures

We study the (newtonian) gravitational force distribution arising from a fractal set of sources. We show that, in the case of real structures in finite samples, an important role is played by morphological properties and finite size effects. For dimensions smaller than d-1 (being $d$ the space dimension) the convergence of the net gravitational force is assured by the fast decaying of the density, while for fractal dimension D>d-1 the morphological properties of the structure determine the eventual convergence of the force as a function of distance. We clarify the role played by the cut-offs of the distribution. Some cosmological implications are discussed.Comment: 9 pages, latex, 2 postscript figures, also available at http://www.phys.uniroma1.it/DOCS/PIL/pil.html Accepted for Publication in Europhysics Letters. Minor modifications adde

Stochastic interacting particle systems out of equilibrium

This paper provides an introduction to some stochastic models of lattice gases out of equilibrium and a discussion of results of various kinds obtained in recent years. Although these models are different in their microscopic features, a unified picture is emerging at the macroscopic level, applicable, in our view, to real phenomena where diffusion is the dominating physical mechanism. We rely mainly on an approach developed by the authors based on the study of dynamical large fluctuations in stationary states of open systems. The outcome of this approach is a theory connecting the non equilibrium thermodynamics to the transport coefficients via a variational principle. This leads ultimately to a functional derivative equation of Hamilton-Jacobi type for the non equilibrium free energy in which local thermodynamic variables are the independent arguments. In the first part of the paper we give a detailed introduction to the microscopic dynamics considered, while the second part, devoted to the macroscopic properties, illustrates many consequences of the Hamilton-Jacobi equation. In both parts several novelties are included.Comment: 36 page

Average observational quantities in the timescape cosmology

We examine the properties of a recently proposed observationally viable alternative to homogeneous cosmology with smooth dark energy, the timescape cosmology. In the timescape model cosmic acceleration is realized as an apparent effect related to the calibration of clocks and rods of observers in bound systems relative to volume-average observers in an inhomogeneous geometry in ordinary general relativity. The model is based on an exact solution to a Buchert average of the Einstein equations with backreaction. The present paper examines a number of observational tests which will enable the timescape model to be distinguished from homogeneous cosmologies with a cosmological constant or other smooth dark energy, in current and future generations of dark energy experiments. Predictions are presented for: comoving distance measures; H(z); the equivalent of the dark energy equation of state, w(z); the Om(z) measure of Sahni, Shafieloo and Starobinsky; the Alcock-Paczynski test; the baryon acoustic oscillation measure, D_v; the inhomogeneity test of Clarkson, Bassett and Lu; and the time drift of cosmological redshifts. Where possible, the predictions are compared to recent independent studies of similar measures in homogeneous cosmologies with dark energy. Three separate tests with indications of results in possible tension with the Lambda CDM model are found to be consistent with the expectations of the timescape cosmology.Comment: 22 pages, 12 figures; v2 discussion, references added, matches published versio

Discrete Matter, Far Fields, and Dark Matter

We show that in cosmology the gravitational action of the far away matter has quite relevant effects, if retardation of the forces and discreteness of matter (with its spatial correlation) are taken into account. The expansion rate is found to be determined by the density of the far away matter, i.e., by the density of matter at remote times. This leads to the introduction of an effective density, which has to be five times larger than the present one, if the present expansion rate is to be accounted for. The force per unit mass on a test particle is found to be of the order of 0.2cH_0. The corresponding contribution to the virial of the forces for a cluster of galaxies is also discussed, and it is shown that it fits the observations if a decorrelation property of the forces at two separated points is assumed. So it appears that the gravitational effects of the far away matter may have the same order of magnitude as the corresponding local effects of dark matter.Comment: 16 pages, 1 figure. LaTex documen

Galaxy distribution and extreme value statistics

We consider the conditional galaxy density around each galaxy, and study its fluctuations in the newest samples of the Sloan Digital Sky Survey Data Release 7. Over a large range of scales, both the average conditional density and its variance show a nontrivial scaling behavior, which resembles to criticality. The density depends, for 10 < r < 80 Mpc/h, only weakly (logarithmically) on the system size. Correspondingly, we find that the density fluctuations follow the Gumbel distribution of extreme value statistics. This distribution is clearly distinguishable from a Gaussian distribution, which would arise for a homogeneous spatial galaxy configuration. We also point out similarities between the galaxy distribution and critical systems of statistical physics

Inclisiran in lipid management: A Literature overview and future perspectives

Primary and secondary prevention protocols aim at reducing the plasma levels of lipids - with particular reference to low-density lipoprotein cholesterol (LDL-C) plasma concentrations – in order to improve the overall survival and reduce the occurrence of major adverse cardiovascular events. The use of statins has been widely considered as the first-line approach in lipids management as they can dramatically impact on the cardiovascular risk profile of individuals. The introduction of ezetimibe and proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors overcame the adverse effects of statins and ameliorate the achievement of the target lipids levels. Indeed, advances in therapies promote the use of specific molecules – i.e. short strands of RNA named small-interfering RNAs (siRNAs) – to suppress the transcription of genes related to lipids metabolism. Recently, the inclisiran has been developed: this is a siRNA able to block the mRNA of the PCSK9 gene. About 50% reduction in low-density lipoprotein cholesterol levels have been observed in randomized controlled trials with inclisiran. The aim of this review was to summarize the literature regarding inclisiran and its possible role in the general management of patients with lipid disorders and/or in primary/secondary prevention protocols

Very large scale correlations in the galaxy distribution

We characterize galaxy correlations in the Sloan Digital Sky Survey by measuring several moments of galaxy counts in spheres. We firstly find that the average counts grows as a power-law function of the distance with an exponent D= 2.1+- 0.05 for r in [0.5,20] Mpc/h and D = 2.8+-0.05 for r in [30,150] Mpc/h. In order to estimate the systematic errors in these measurements we consider the counts variance finding that it shows systematic finite size effects which depend on the samples sizes. We clarify, by making specific tests, that these are due to galaxy long-range correlations extending up to the largest scales of the sample. The analysis of mock galaxy catalogs, generated from cosmological N-body simulations of the standard LCDM model, shows that for r<20 Mpc/h the counts exponent is D~2.0, weakly dependent on galaxy luminosity, while D=3 at larger scales. In addition, contrary to the case of the observed galaxy samples, no systematic finite size effects in the counts variance are found at large scales, a result that agrees with the absence of large scale, r~100 Mpc/h, correlations in the mock catalogs. We thus conclude that the observed galaxy distribution is characterized by correlations, fluctuations and hence structures, which are larger, both in amplitude and in spatial extension, than those predicted by the standard model LCDM of galaxy formation.Comment: 6 pages, 7 figures to be published in Europhysics Letter