294 research outputs found
Effects of Rating Scale Direction under the Condition of Different Reading Direction
Because response scales serve as orientation for respondents when mapping their answers to response categories, it can be expected that the decremental (from positive to negative) or incremental (from negative to positive) order of a response scale provides information that influences response behavior. If respondents interpret the first category on a scale as signifying "most accepted," then starting an agree/disagree scale with "agree completely" or "disagree completely" may result in their forming different subjective hypotheses about the "most acceptable" response. If this principle applies in general, respondents' reactions to horizontal response scales with different orders of response categories should be similar in the two directions of reading - right to left or left to right. This paper tests two hypotheses: first, that decremental scales elicit more positive responses than incremental scales; second, that this pattern holds under the condition of different reading direction. These hypotheses were tested using a German and an Israeli student sample. Seven-point decremental and incremental scales were applied in each sample; only the scale endpoints were verbally labeled. The questions asked related to extrinsic and intrinsic job motivation and achievement motivation. For data collection, a split-ballot design with random assignment of respondents to decremental and incremental scales was applied in both samples. Results revealed that response-order effects occur similarly in the right-to-left and the left-to-right reading direction
Testing for Majorana Zero Modes in a Px+iPy Superconductor at High Temperature by Tunneling Spectroscopy
Directly observing a zero energy Majorana state in the vortex core of a
chiral superconductor by tunneling spectroscopy requires energy resolution
better than the spacing between core states . We show that
nevertheless, its existence can be decisively tested by comparing the
temperature broadened tunneling conductance of a vortex with that of an
antivortex even at temperatures .Comment: 5 pages, 4 figure
Mitochondrial Involvement in Vertebrate Speciation? The Case of Mito-nuclear Genetic Divergence in Chameleons
Compatibility between the nuclear (nDNA) and mitochondrial (mtDNA) genomes is important for organismal health. However, its significance for major evolutionary processes such as speciation is unclear, especially in vertebrates. We previously identified a sharp mtDNA-specific sequence divergence between morphologically indistinguishable chameleon populations (Chamaeleo chamaeleon recticrista) across an ancient Israeli marine barrier (Jezreel Valley). Because mtDNA introgression and gender-based dispersal were ruled out, we hypothesized that mtDNA spatial division was maintained by mito-nuclear functional compensation. Here, we studied RNA-seq generated from each of ten chameleons representing the north and south populations and identified candidate nonsynonymous substitutions (NSSs) matching the mtDNA spatial distribution. The most prominent NSS occurred in 14 nDNA-encoded mitochondrial proteins. Increased chameleon sample size (N = 70) confirmed the geographic differentiation in POLRMT, NDUFA5, ACO1, LYRM4, MARS2, and ACAD9. Structural and functionality evaluation of these NSSs revealed high functionality. Mathematical modeling suggested that this mito-nuclear spatial divergence is consistent with hybrid breakdown. We conclude that our presented evidence and mathematical model underline mito-nuclear interactions as a likely role player in incipient speciation in vertebrates
Reporting Misconduct of a Coworker to Protect a Patient: A Comparison between Experienced Nurses and Nursing Students
Purpose. Whistleblowing is the reporting of illegal, immoral, or illegitimate practices to persons or organizations that may affect the action. The current study compares experienced nurses to nursing students regarding their willingness to blow the whistle to protect a patient's interests. Methods. 165 participants were divided into two groups: 82 undergraduate nursing students and 83 experienced nurses. Participants responded to two vignettes that described a colleague's and a manager's misconduct at work. Results. The nursing students perceived the severity of the misconduct significantly lower compared to the experienced nurses. The nursing students also ranked the internal and external whistleblowing indices higher than the nurses, but the differences did not reach statistical significance. For each of the examined internal and external indices, professional experience was found to be significant in multivariate regression analyses. Conclusions. Even though nursing students perceived the severity of the misconduct significantly lower than the experienced nurses, the students demonstrated a greater readiness to blow the whistle, both internally and externally. Recommendations for handling comparable situations are offered
Majorana fermions on a disordered triangular lattice
Vortices of several condensed matter systems are predicted to have
zero-energy core excitations which are Majorana fermions. These exotic
quasi-particles are neutral, massless, and expected to have non-Abelian
statistics. Furthermore, they make the ground state of the system highly
degenerate. For a large density of vortices, an Abrikosov lattice is formed,
and tunneling of Majorana fermions between vortices removes the energy
degeneracy. In particular the spectrum of Majorana fermions in a triangular
lattice is gapped, and the Hamiltonian which describes such a system is
antisymmetric under time-reversal. We consider Majorana fermions on a
disordered triangular lattice. We find that even for very weak disorder in the
location of the vortices localized sub-gap modes appear. As the disorder
becomes strong, a percolation phase transition takes place, and the gap is
fully closed by extended states. The mechanism that underlies these phenomena
is domain walls between two time-reversed phases, which are created by flipping
the sign of the tunneling matrix elements. The density of states in the
disordered lattice seems to diverge at zero energy.Comment: 19 pages, 10 figure
Continuous Team Semantics
We study logics with team semantics in computable metric spaces. We show how to define approximate versions of the usual independence/dependence atoms. For restricted classes of formulae, we show that we can assume w.l.o.g.~that teams are closed sets. This then allows us to import techniques from computable analysis to study the complexity of formula satisfaction and model checking
RNA editing signature during myeloid leukemia cell differentiation
Adenosine deaminases acting on RNA (ADARs) are key proteins for hematopoietic stem cell self-renewal and for survival of differentiating progenitor cells. However, their specific role in myeloid cell maturation has been poorly investigated. Here we show that ADAR1 is present at basal level in the primary myeloid leukemia cells obtained from patients at diagnosis as well as in myeloid U-937 and THP1 cell lines and its expression correlates with the editing levels. Upon phorbol-myristate acetate or Vitamin D3/granulocyte macrophage colony-stimulating factor (GM-CSF)-driven differentiation, both ADAR1 and ADAR2 enzymes are upregulated, with a concomitant global increase of A-to-I RNA editing. ADAR1 silencing caused an editing decrease at specific ADAR1 target genes, without, however, interfering with cell differentiation or with ADAR2 activity. Remarkably, ADAR2 is absent in the undifferentiated cell stage, due to its elimination through the ubiquitin–proteasome pathway, being strongly upregulated at the end of the differentiation process. Of note, peripheral blood monocytes display editing events at the selected targets similar to those found in differentiated cell lines. Taken together, the data indicate that ADAR enzymes play important and distinct roles in myeloid cells
Taking It to the Extreme:The Effect of Coalition Cabinets on Foreign Policy
Institutional constraints have been offered by some scholars as an explanation for why multiparty coalitions should be more peaceful than single-party cabinets. Yet others see the same institutional setting as a prescription for more aggressive behavior. Recent research has investigated these conflicting expectations, but with mixed results. We examine the theoretical bases for these alternative expectations about the effects of coalition politics on foreign policy. We find that previous research is limited theoretically by confounding institutional effects with policy positions, and empirically by analyzing only international conflict data. We address these limitations by examining cases of foreign policy behavior using the World Event/Interaction Survey (WEIS) dataset. Consistent with our observation that institutional constraints have been confounded with policy positions, we find that coalitions are neither more aggressive nor more peaceful, but do engage in more extreme foreign policy behaviors. These findings are discussed with regard to various perspectives on the role of institutions in shaping foreign policy behavior.</p
Patterns of use of perioperative angiotensin-converting enzyme inhibitors in coronary artery bypass graft surgery with cardiopulmonary bypass: Effects on in-hospital morbidity and mortality
Background-Despite proven benefit in ambulatory patients with ischemic heart disease, the pattern of use of angiotensin-converting enzyme inhibitors (ACEIs) in coronary artery bypass graft surgery has been erratic and controversial. Methods and Results-This is a prospective observational study of 4224 patients undergoing coronary artery bypass graft surgery. The cohort included 1838 patients receiving ACEI therapy before surgery and 2386 (56.5%) without ACEI exposure. Postoperatively, the pattern of ACEI use yielded 4 groups: continuation, 915 (21.7%); withdrawal, 923 (21.8%); addition, 343 (8.1%); and no ACEI, 2043 (48.4%). Continuous treatment with ACEI versus no ACEI was associated with substantive reductions of risk of nonfatal events (adjusted odds ratio for the composite outcome, 0.69; 95% confidence interval, 0.52-0.91; P=0.009) and a cardiovascular event (odds ratio, 0.64; 95% confidence interval, 0.46-0.88; P=0.006). Addition of ACEI de novo postoperatively compared with no ACEI therapy was also associated with a significant reduction of risk of composite outcome (odds ratio, 0.56; 95% confidence interval, 0.38-0.84; P=0.004) and a cardiovascular event (odds ratio, 0.63; 95% confidence interval, 0.40-0.97; P=0.04). On the other hand, continuous treatment of ACEI versus withdrawal of ACEI was associated with decreased risk of the composite outcome (odds ratio, 0.50; 95% confidence interval, 0.38-0.66; P<0.001), as well as a decrease in cardiac and renal events (P<0.001 and P=0.005, respectively). No differences in in-hospital mortality and cerebral events were noted. Conclusions-Our study suggests that withdrawal of ACEI treatment after coronary artery bypass graft surgery is associated with nonfatal in-hospital ischemic events. Furthermore, continuation of ACEI or de novo ACEI therapy early after cardiac surgery is associated with improved in-hospital outcomes
- …