1,191 research outputs found

    Impossible decision? An investigation of risk trade-offs in the intensive care unit

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    In the intensive care unit (ICU), clinicians must often make risk trade-offs on patient care. For example, on deciding whether to discharge a patient before they have fully recovered in order to create a bed for another, sicker, patient. When misjudged, these decisions can negatively influence patient outcomes: yet it can be difficult, if not impossible, for clinicians to evaluate with certainty the safest course of action. Using a vignette-based interview methodology, a naturalistic decision-making approach was utilised to study this phenomena. The decision preferences of ICU clinicians (n=24) for two common risk trade-off scenarios were investigated. Qualitative analysis revealed the sample of clinicians to reach different, and sometimes oppositional, decision preferences. These practice variations emerged from differing analyses of risk, how decisions were ‘framed’ (e.g. philosophies on care), past experiences, and perceptions of group and organisational norms. Implications for patient safety and clinical decision-making are discussed

    Massively parallelizable list-mode reconstruction using a Monte Carlo-based elliptical Gaussian model

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    Purpose: A fully three-dimensional (3D) massively parallelizable list-mode ordered-subsets expectation-maximization (LM-OSEM) reconstruction algorithm has been developed for high-resolution PET cameras. System response probabilities are calculated online from a set of parameters derived from Monte Carlo simulations. The shape of a system response for a given line of response (LOR) has been shown to be asymmetrical around the LOR. This work has been focused on the development of efficient region-search techniques to sample the system response probabilities, which are suitable for asymmetric kernel models, including elliptical Gaussian models that allow for high accuracy and high parallelization efficiency. The novel region-search scheme using variable kernel models is applied in the proposed PET reconstruction algorithm...This work was partially supported by Spain’s Ministry of Science and Innovation through CDTI’s CENIT program (AMIT project) and INNPACTO (PRECISION project), Instituto de Salud Carlos III (PI09/91058 and PI09/91065), and Project Nos. TEC2010-21619-C04-03 and TEC2011-28972- C02-02, Comunidad de Madrid (ARTEMIS S2009/DPI- 1802), and the European Regional Development Funds (FEDER). CIBER-BBN is an initiative funded by the VI National R&D&i Plan 2008–2011, Iniciativa Ingenio 2010, Consolider Program, CIBER Actions, and finance by the Instituto de Salud Carlos III with assistance from the European Regional Development Fund.Publicad

    EUV spectra of highly-charged ions W54+^{54+}-W63+^{63+} relevant to ITER diagnostics

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    We report the first measurements and detailed analysis of extreme ultraviolet (EUV) spectra (4 nm to 20 nm) of highly-charged tungsten ions W54+^{54+} to W63+^{63+} obtained with an electron beam ion trap (EBIT). Collisional-radiative modelling is used to identify strong electric-dipole and magnetic-dipole transitions in all ionization stages. These lines can be used for impurity transport studies and temperature diagnostics in fusion reactors, such as ITER. Identifications of prominent lines from several W ions were confirmed by measurement of isoelectronic EUV spectra of Hf, Ta, and Au. We also discuss the importance of charge exchange recombination for correct description of ionization balance in the EBIT plasma.Comment: 11 pages, 4 figure

    Note on Tests of the Factorization Hypothesis and the Determination of Meson Decay Constants

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    We discuss various tests of the factorization hypothesis making use of the close relationship between semi-leptonic and factorized nonleptonic decay amplitudes. It is pointed out that factorization leads to truely model-independent predictions for the ratio of nonleptonic to semi-leptonic decay rates, if in the nonleptonic decay a spin one meson of arbitrary mass or a pion take the place of the lepton pair. Where the decay constants of those mesons are known, these predictions represent ideal tests of the factorization hypothesis. In other cases they may be used to extract the decay constants. Currently available data on the decays Bˉ0D+π,D+π,D+ϱ,D+ϱ\bar B^0 \to D^+\pi^-,\, D^{*+}\pi^-,\, D^+\varrho^-,\, D^{*+}\varrho^- are shown to be in excellent agreement with the factorization results. A weighted average of the four independent values for the QCD coefficient a1a_1 extracted from the data gives a1=1.15±0.06a_1=1.15\pm 0.06 suggesting that it may be equal to the Wilson coefficient c1(μ)c_1(\mu) evaluated at the scale μ=mb\mu = m_b.Comment: (9 pages, ReVTeX, no figures), HD-THEP-92-3

    Flux Tube Zero-Point Motion, Hadronic Charge Radii, and Hybrid Meson Production Cross Sections

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    Flux tube zero-point motion produces quark displacements transverse to the flux tube which make significant contributions to hadronic charge radii. In heavy quark systems, these contributions can be related by Bjorken's sum rule to the rates for semileptonic decay to hybrid mesons. This connection can be generalized to other leptoproduction processes, where transverse contributions to elastic form factor slopes are related to the cross sections for the production of the associated hybrid states. I identify the flux tube overlap integral responsible for these effects as the strong QCD analogue of the Sudakov form factor of perturbative QCD.Comment: 16 pages, revised to clarify some points and to improve and correct the notation for the flux tube wave function
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