596 research outputs found

    Journal off Mechanical Design The Application of Curvature Theory to the Trajectory Generation Problem of Robot Manipulators

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    This paper illustrates a new application of planar curvature theory to the geometric problem of trajectory generation by a two-link manipulator. The theory yields the instantaneous speed ratio, and the rate of change of the speed ratio, which correspond to the geometry of a desired point trajectory. Separate from the purely geometric speed ratio problem (i.e., the coordination problem) is the time based problem of controlling the joint rates in order to move with the specified path variables. Introduction A rigid body, constrained to move in a plane with N independent degrees of freedom, where 1 < N < 3, is known as a planar TV-parameter motion, denoted by M N . This paper discusses the arm-subassembly of a planar manipulator, whose terminal link is a planar M 2 motion. The purpose is to illustrate a new application of classical curvature theory to the problem of trajectory generation by a multi-degree-of-freedom rigid body system, in this case a planar robot manipulator. Previously, curvature theory has been applied to the dimensional synthesis of planar mechanisms. The new application of the theory illustrated here is a problem of motion synthesis by industrial manipulators

    A stochastic model for the evolution of the web allowing link deletion

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    Recently several authors have proposed stochastic evolutionary models for the growth of the web graph and other networks that give rise to power-law distributions. These models are based on the notion of preferential attachment leading to the ``rich get richer'' phenomenon. We present a generalisation of the basic model by allowing deletion of individual links and show that it also gives rise to a power-law distribution. We derive the mean-field equations for this stochastic model and show that by examining a snapshot of the distribution at the steady state of the model, we are able to tell whether any link deletion has taken place and estimate the link deletion probability. Our model enables us to gain some insight into the distribution of inlinks in the web graph, in particular it suggests a power-law exponent of approximately 2.15 rather than the widely published exponent of 2.1

    A One Health Framework for the Evaluation of Rabies Control Programmes: A Case Study from Colombo City, Sri Lanka

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    <div><p>Background</p><p>One Health addresses complex challenges to promote the health of all species and the environment by integrating relevant sciences at systems level. Its application to zoonotic diseases is recommended, but few coherent frameworks exist that combine approaches from multiple disciplines. Rabies requires an interdisciplinary approach for effective and efficient management.</p><p>Methodology/Principal Findings</p><p>A framework is proposed to assess the value of rabies interventions holistically. The economic assessment compares additional monetary and non-monetary costs and benefits of an intervention taking into account epidemiological, animal welfare, societal impact and cost data. It is complemented by an ethical assessment. The framework is applied to Colombo City, Sri Lanka, where modified dog rabies intervention measures were implemented in 2007. The two options included for analysis were the control measures in place until 2006 (“baseline scenario”) and the new comprehensive intervention measures (“intervention”) for a four-year duration. Differences in control cost; monetary human health costs after exposure; Disability-Adjusted Life Years (DALYs) lost due to human rabies deaths and the psychological burden following a bite; negative impact on animal welfare; epidemiological indicators; social acceptance of dogs; and ethical considerations were estimated using a mixed method approach including primary and secondary data. Over the four years analysed, the intervention cost US $1.03 million more than the baseline scenario in 2011 prices (adjusted for inflation) and caused a reduction in dog rabies cases; 738 DALYs averted; an increase in acceptability among non-dog owners; a perception of positive changes in society including a decrease in the number of roaming dogs; and a net reduction in the impact on animal welfare from intermediate-high to low-intermediate.</p><p>Conclusions</p><p>The findings illustrate the multiple outcomes relevant to stakeholders and allow greater understanding of the value of the implemented rabies control measures, thereby providing a solid foundation for informed decision-making and sustainable control.</p></div

    Organization of networks with tagged nodes and biased links: a priori distinct communities. The case of Intelligent Design Proponents and Darwinian Evolution Defenders

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    Among topics of opinion formation it is of interest to observe the characteristics of networks with a priori distinct communities. As an illustration, we report on the citation network(s) unfolded in the recent decades through web available works belonging to selected members of the Neocreationist and Intelligent Design Proponents (IDP) and the Darwinian Evolution Defenders (DED) communities. An adjacency matrix of tagged nodes is first constructed; it is not symmetric. A generalization of considerations pertaining to the case of networks with biased links, directed or undirected, is thus presented. The main characteristic coefficients describing the structure of such partially directed networks with tagged nodes are outlined. The structural features are discussed searching for statistical aspects, equivalence or not of subnetworks through the degree distributions, each network assortativity, the global and local clustering coefficients and the Average Overlap Indices. The various closed and open triangles made from nodes, moreover distinguishing the community, are especially listed to calculate the clustering characteristics. The distribution of elements in the rectangular submatrices are specially examined since they represent inter-community connexions. The emphasis being on distinguishing the number of vertices belonging to a given community. Using such informations one can distinguish between opinion leaders, followers and main rivals and briefly interpret their relationships through psychological-like conditions intrinsic to behavior rules in either community. Considerations on other controversy cases with similar social constraints are outlined, as well as suggestions on further, more general, work deduced from our observations on such networks.Comment: 40 pages, 61 references, 7 Tables, 11 Figures, 2 Appendices (giving the adjacency matrices

    Empirical analysis of web-based user-object bipartite networks

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    Understanding the structure and evolution of web-based user-object networks is a significant task since they play a crucial role in e-commerce nowadays. This Letter reports the empirical analysis on two large-scale web sites, audioscrobbler.com and del.icio.us, where users are connected with music groups and bookmarks, respectively. The degree distributions and degree-degree correlations for both users and objects are reported. We propose a new index, named collaborative clustering coefficient, to quantify the clustering behavior based on the collaborative selection. Accordingly, the clustering properties and clustering-degree correlations are investigated. We report some novel phenomena well characterizing the selection mechanism of web users and outline the relevance of these phenomena to the information recommendation problem.Comment: 6 pages, 7 figures and 1 tabl

    Pharmacologic modulation of experimentally induced allergic asthma

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    Allergic asthma is the most frequent disease of the respiratory tract. The aim of the current experimental and clinical studies was to find new sources of drugs able to control asthmatic inflammation and airway hyperresponsiveness. Our experimental studies were focused on efficiency evaluation of substances able to influence activities of ion channels, phosphodiesterase (PDE) isoforms, substances from the group of polyphenols and NO metabolism modulators during experimentally induced allergic asthma
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