Spatially incoherent modulational instability in a non local medium

We investigate one-dimensional transverse modulational instability in a non local medium excited with a spatially incoherent source. Employing undoped nematic liquid crystals in a planar pre-tilted configuration, we investigate the role of the spectral broadening induced by incoherence in conjunction with the spatially non local molecular reorientation. The phenomenon is modeled using the Wigner transform.Comment: 13 pages with 4 figures included. To be published in Laser Physics Letter

Aging in K1−x_{1-x}Lix_xTa03_3: a domain growth interpretation

The aging behaviour of the a.c. susceptibility of randomly substituted K$_{1-x}$Li$_x$Ta0$_3$ crystals reveals marked differences with spin-glasses in that cooling rate effects are very important. The response to temperature steps (including temperature cycles) was carefully studied. A model based on thermally activated domain growth accounts for all the experimental results, provided one allows for a large distribution of pinning energies, in such a way that `slow' and `fast' domains coexist. Interesting similarities with deeply supercooled liquids are underlined.Comment: 4 pages. Preprint LPTENS/9820, submitted to Phys. Rev. Let

Unmet needs in ANCA-associated vasculitis: Physicians’ and patients’ perspectives

In recent years, clinical research has increased significantly and therapies for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis have improved. However, there are still unanswered questions and unmet needs about AAV patients. The purpose of this review is to examine the frontiers of research related to emerging biomarkers eventually predicting relapse, and new therapeutic approaches, not to mention new quality of life assessment tools. Identifying predictors of relapse may help optimize therapeutic strategies, minimize disease recurrence, and reduce treatment-related side effects. In addition, it is important to recognize that patients may suffer long-term consequences of the disease and its treatment, which, although life-saving, is often associated with significant side effects. Our goal, therefore, is to highlight what has been achieved, the pitfalls, and what still needs to be done, comparing the views of physicians and patients

Blumgart Anastomosis After Pancreaticoduodenectomy. A Comprehensive Systematic Review, Meta-Analysis, and Meta-Regression

Background: The superiority of Blumgart anastomosis (BA) over non-BA duct to mucosa (non-BA DtoM) still remains under debate. Methods: We performed a systematic search of studies comparing BA to non-BA DtoM. The primary endpoint was CR-POPF. Postoperative morbidity and mortality, post-pancreatectomy hemorrhage (PPH), delayed gastric emptying (DGE), reoperation rate, and length of stay (LOS) were evaluated as secondary endpoints. The meta-analysis was carried out using random effect. The results were reported as odds ratio (OR), risk difference (RD), weighted mean difference (WMD), and number needed to treat (NNT). Results: Twelve papers involving 2368 patients: 1075 BA and 1193 non-BA DtoM were included. Regarding the primary endpoint, BA was superior to non-BA DtoM (RD = 0.10; 95% CI: −0.16 to −0.04; NNT = 9). The multivariate ORs' meta-analysis confirmed BA's protective role (OR 0.26; 95% CI: 0.09 to 0.79). BA was superior to DtoM regarding overall morbidity (RD = −0.10; 95% CI: −0.18 to −0.02; NNT = 25), PPH (RD = −0.03; 95% CI −0.06 to −0.01; NNT = 33), and LOS (− 4.2 days; −7.1 to −1.2 95% CI). Conclusion: BA seems to be superior to non-BA DtoM in avoiding CR-POPF

Memory Effects in Granular Material

We present a combined experimental and theoretical study of memory effects in vibration-induced compaction of granular materials. In particular, the response of the system to an abrupt change in shaking intensity is measured. At short times after the perturbation a granular analog of aging in glasses is observed. Using a simple two-state model, we are able to explain this short-time response. We also discuss the possibility for the system to obey an approximate pseudo-fluctuation-dissipation theorem relationship and relate our work to earlier experimental and theoretical studies of the problem.Comment: 5 pages, 4 figures, reference list change

Mean-field theory of temperature cycling experiments in spin-glasses

We study analytically the effect of temperature cyclings in mean-field spin-glasses. In accordance with real experiments, we obtain a strong reinitialization of the dynamics on decreasing the temperature combined with memory effects when the original high temperature is restored. The same calculation applied to mean-field models of structural glasses shows no such reinitialization, again in accordance with experiments. In this context, we derive some relations between experimentally accessible quantities and propose new experimental protocols. Finally, we briefly discuss the effect of field cyclings during isothermal aging.Comment: Some misprints corrected, references updated, final version to apper in PR

Chaotic, memory and cooling rate effects in spin glasses: Is the Edwards-Anderson model a good spin glass?

We investigate chaotic, memory and cooling rate effects in the three dimensional Edwards-Anderson model by doing thermoremanent (TRM) and AC susceptibility numerical experiments and making a detailed comparison with laboratory experiments on spin glasses. In contrast to the experiments, the Edwards-Anderson model does not show any trace of re-initialization processes in temperature change experiments (TRM or AC). A detailed comparison with AC relaxation experiments in the presence of DC magnetic field or coupling distribution perturbations reveals that the absence of chaotic effects in the Edwards-Anderson model is a consequence of the presence of strong cooling rate effects. We discuss possible solutions to this discrepancy, in particular the smallness of the time scales reached in numerical experiments, but we also question the validity of the Edwards-Anderson model to reproduce the experimental results.Comment: 17 pages, 10 figures. The original version of the paper has been split in two parts. The second part is now available as cond-mat/010224

Recent Developments on the Silicon Drift Detector readout scheme for the ALICE Inner Tracking System

Proposal of abstract for LEB99, Snowmass, Colorado, 20-24 September 1999Recent developments of the Silicon Drift Detector (SDD) readout system for the ALICE Experiment are presented. The foreseen readout system is based on 2 main units. The first unit consists of a low noise preamplifier, an analog memory which continuously samples the amplifier output, an A/D converter and a digital memory. When the trigger signal validates the analog data, the ADCs convert the samples into a digital form and store them into the digital memory. The second unit performs the zero suppression/data compression operations. In this paper the status of the design is presented, together with the test results of the A/D converter, the multi-event buffer and the compression unit prototype.Summary:In the Inner Tracker System (ITS) of the ALICE experiment the third and the fourth layer of the detectors are SDDs. These detectors provide the measurement of both the energy deposition and the bi-dimensional position of the track. In terms of readout an SDD can be viewed as a matrix, where the rows are the detector anodes and the columns are the samples to be read during the drift time; therefore, a very large amount of data has to be amplified, converted in digital form and preprocessed in order to avoid the storage of non-significatn data.Since the electron mobility is a strong temperature function, detector temperature has to be kept constant; on the other hand, it is not possible to use very efficient cooling systems because the amount of material in this area is very limited, so the power budget for the electronic readout is very low (less than 6 mW/anode).The simplest solution would be to send the analog signals outside the sensitive area immediately after a preamplification; unfortunately, the ratio between the number of channels (around 200 000) and the space available is so high that the simple solution of sending all the SDD anodes output outside teh detector zone after a low-noise amplification is not practically manageable.Abstract:The adopted solution is based on three main units:(i) A front-end chip that performs low noise amplification, fast analog storage and A/D conversion(ii) A multi-event digital buffer for data derandomization(iii) A data compression/zero suppression and system control boardThe first two units are distributed on the ladders near the detectors and have stringent power and space requirements, while the third unit is placed at both ends of the ladders and in boxes placed on both ends of the TPC detector.The first unit is the most critical part of the system. It works as follows: the detector signals are continuously amplified, sampled and stored in the analog memory with a frequency of 40 MSamples/s The L0d trigger signal stops the write operation, while the L1 trigger signal starts the conversion phase. This phase will continue until the event data are stored in the event buffer if the L2y confirm trigger signal is received, or rejected if the L2n abort signal will be issued by the trigger system.Prototypes of the three parts have been designed and tested while the full chip is currently under design. Tests of the A/D converter will be presented.The multi-event buffer purpose is to de-randomize the even data in order to reduce the transmission speed. Preliminary tests of the first prototype will be presented.The board placed at the end of the ladders performs various functions. It reduces the amount of data through various cascaded algorithms with variable parameters and transmits the data to the SIU board. It also controls the test and slow control system for the ladder circuitry. Tests of the FPGA-based prototypes will be presented.Special care has been taken for the test problem. The ASICs designed are provided of a test control port based on teh IEEE 1149.1 JTAG standard. The same protocol is used for downloading configuration information

Test Results of the ALICE SDD Electronic Readout Prototypes

The first prototypes of the front-end electronics of the ALICE silicon driftdetectors have been designed and tested. The integrated circuits have been designed using state of the art technologies and, for the analog parts, with radiation-tolerantdesign techniques. In this paper, the test results of the building blocks of the PASCAL chip and the first prototype of the AMBRA chip are presented. The prototypes fully respect the ALICE requirements; owingto the use of deep-submicron technologies together with radiation-tolerant layout techniques, the prototypes have shown a toleranceto a radiation dose much higher than the one foreseen for the ALICE environment.(Abstract only available, full text to follow)

Enzymatic pre-treatment of fruit pomace for fibre hydrolysis and antioxidants release

Processing of grapes and other fruits in the wine and fruit juice industry generates huge amounts of solid residues (pomace) which, if not properly disposed of, can represent an environmental concern due to their high organic load. To avoid landfill and incineration, different alternative uses are available and commonly applied. Among these, the most common are for feeding, composting and biogas production which are, anyway, not proper valorisation strategies. On the other hand, fruit pomaces are by-products still rich in bioactive components, such as dietary fibre and phenolic/antioxidant compounds. Considering the positive health potentials of such components, together with their potential technological role (as texturing and antioxidant ingredients), fruit pomaces may then be simply dried and milled to get functional food ingredients. It is known however, that incorporation of high levels of raw fibres into food products often causes unpleasant textures and colours. Furthermore, phenolic compounds only partially occur in fruit pomace as free compounds, while they are bound to cell wall (fibre) fractions. Enzymatic hydrolysis processes could be applied as a pre-drying treatment of fruit pomace to improve the functional properties of the final powders in terms of fibre composition and antioxidants release. In this study different fruit skins separated from different pomaces (grape, apple and blackcurrant) were submitted to an enzymatic treatment before drying. Two different commercial pectinase preparations were used: One already used in the apple juice processing for the treatment of apple and blackcurrant skins, the other currently used in the winemaking process for the treatment of grape skins. Untreated and treated dried skins were analysed for structural carbohydrates, soluble and insoluble dietary fibre, free glucose and xylose, water holding capacity, water solubility and total phenolics and antioxidants release. The results were highly variable depending on the fruit type, probably due to a different cell wall composition which requires targeted enzyme selection. In general, the enzyme treatment led to an increase in water solubility, water and oil holding capacity and free monosaccharides. Release of antioxidant compounds was observed only for apple peels