329 research outputs found
Monoclonal antibodies against seven sites on the head and tail of Dictyostelium myosin.
Human Fc gamma RIII: cloning, expression, and identification of the chromosomal locus of two Fc receptors for IgG.
Dictyostelium myosin: characterization of chymotryptic fragments and localization of the heavy-chain phosphorylation site.
The Kolmogorov-Smirnov test and its use for the identification of fireball fragmentation
We propose an application of the Kolmogorov-Smirnov test for rapidity
distributions of individual events in ultrarelativistic heavy ion collisions.
The test is particularly suitable to recognise non-statistical differences
between the events. Thus when applied to a narrow centrality class it could
indicate differences between events which would not be expected if all events
evolve according to the same scenario. In particular, as an example we assume
here a possible fragmentation of the fireball into smaller pieces at the
quark/hadron phase transition. Quantitative studies are performed with a Monte
Carlo model capable of simulating such a distribution of hadrons. We conclude
that the Kolmogorov-Smirnov test is a very powerful tool for the identification
of the fragmentation process.Comment: 9 pages, 10 figure
Orchestrating Tuple-based Languages
The World Wide Web can be thought of as a global computing architecture supporting the deployment of distributed networked applications. Currently, such applications can be programmed by resorting mainly to two distinct paradigms: one devised for orchestrating distributed services, and the other designed for coordinating distributed (possibly mobile) agents. In this paper, the issue of designing a pro-
gramming language aiming at reconciling orchestration and coordination is investigated. Taking as starting point the orchestration calculus Orc and the tuple-based coordination language Klaim, a new formalism is introduced combining concepts and primitives of the original calculi.
To demonstrate feasibility and effectiveness of the proposed approach, a prototype implementation of the new formalism is described and it is then used to tackle a case study dealing with a simplified but realistic electronic marketplace, where a number of on-line stores allow client
applications to access information about their goods and to place orders
Carrier - envelope phase-tagged imaging of the controlled electron acceleration from SiO2 nanospheres in intense few-cycle laser fields
Waveform-controlled light fields offer the possibility of manipulating
ultrafast electronic processes on sub-cycle timescales. The optical lightwave
control of the collective electron motion in nanostructured materials is key
to the design of electronic devices operating at up to petahertz frequencies.
We have studied the directional control of the electron emission from 95 nm
diameter SiO2 nanoparticles in few-cycle laser fields with a well-defined
waveform. Projections of the three-dimensional (3D) electron momentum
distributions were obtained via single-shot velocity-map imaging (VMI), where
phase tagging allowed retrieving the laser waveform for each laser shot. The
application of this technique allowed us to efficiently suppress background
contributions in the data and to obtain very accurate information on the
amplitude and phase of the waveform-dependent electron emission. The
experimental data that are obtained for 4 fs pulses centered at 720 nm at
different intensities in the range (1â4) Ă 1013 W cmâ2 are compared to quasi-
classical mean-field Monte-Carlo simulations. The model calculations identify
electron backscattering from the nanoparticle surface in highly dynamical
localized fields as the main process responsible for the energetic electron
emission from the nanoparticles. The local field sensitivity of the electron
emission observed in our studies can serve as a foundation for future research
on propagation effects for larger particles and field-induced material changes
at higher intensities
An all-solid-state laser source at 671 nm for cold atom experiments with lithium
We present an all solid-state narrow line-width laser source emitting
output power at delivered in a
diffraction-limited beam. The \linebreak source is based on a
fre-quency-doubled diode-end-linebreak pumped ring laser operating on the
transition in Nd:YVO. By using
periodically-poled po-tassium titanyl phosphate (ppKTP) in an external build-up
cavity, doubling efficiencies of up to 86% are obtained. Tunability of the
source over is accomplished. We demonstrate the suitability of
this robust frequency-stabilized light source for laser cooling of lithium
atoms. Finally a simplified design based on intra-cavity doubling is described
and first results are presented
Non-Local Configuration of Component Interfaces by Constraint Satisfaction
© 2020 Springer-Verlag. The final publication is available at Springer via https://doi.org/10.1007/s10601-020-09309-y.Service-oriented computing is the paradigm that utilises services as fundamental elements for developing applications. Service composition, where data consistency becomes especially important, is still a key challenge for service-oriented computing. We maintain that there is one aspect of Web service communication on the data conformance side that has so far escaped the researchers attention. Aggregation of networked services gives rise to long pipelines, or quasi-pipeline structures, where there is a profitable form of inheritance called flow inheritance. In its presence, interface reconciliation ceases to be a local procedure, and hence it requires distributed constraint satisfaction of a special kind. We propose a constraint language for this, and present a solver which implements it. In addition, our approach provides a binding between the language and C++, whereby the assignment to the variables found by the solver is automatically translated into a transformation of C++ code. This makes the C++ Web service context compliant without any further communication. Besides, it uniquely permits a very high degree of flexibility of a C++ coded Web service without making public any part of its source code.Peer reviewe
Obesity is not associated with disease-free interval, melanoma-specific survival, or overall survival in patients with clinical stage IB-II melanoma after SLNB
BACKGROUND AND OBJECTIVES: Clinicopathologic characteristics have prognostic value in clinical stage IBâII patients with melanoma. Little is known about the prognostic value of obesity that has been associated with an increased risk for several cancer types and worsened prognosis after diagnosis. This study aims to examine effects of obesity on outcome in patients with clinical stage IBâII melanoma. METHODS: Prospectively recorded data of patients with clinical stage IBâII melanoma who underwent sentinel lymph node biopsy (SLNB) between 1995 and 2018 at the University Medical Center of Groningen were collected from medical files and retrospectively analyzed. Coxâregression analyses were used to determine associations between obesity (body mass index>â30), tumor (location, histology, Breslowâthickness, ulceration, mitotic rate, SLNâstatus) and patientârelated variables (gender, age, and socialâeconomicâstatus [SES]) and diseaseâfree interval (DFI), melanomaâspecific survival (MSS), and overall survival (OS). RESULTS: Of the 715 patients, 355 (49.7%) were women, median age was 55 (range 18.6â89) years, 149 (20.8%) were obese. Obesity did not significantly affect DFI (adjusted hazard ratio [HR]â=â1.40; 95% confidence interval [CI]â=â0.98â2.00; pâ=â0.06), MSS (adjusted HRâ=â1.48;95%CIâ=â0.97â2.25; pâ=â0.07), and OS (adjusted HRâ=â1.25; 95% CIâ=â0.85â1.85; pâ=â0.25). Increased age, arm location, increased Breslowâthickness, ulceration, increased mitotic rate, and positive SLNâstatus were significantly associated with decreased DFI, MSS, and OS. Histology, sex, and SES were not associated. CONCLUSION: Obesity was not associated with DFI, MSS, or OS in patients with clinical stage IBâII melanoma who underwent SLNB
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