8,773 research outputs found

    Reconciliation of object interaction models

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    This paper presents Reconciliation+, a tool-supported method which identifies overlaps between models of different object interactions expressed as UML sequence and/or collaboration diagrams, checks whether the overlapping elements of these models satisfy specific consistency rules, and guides developers in handling these inconsistencies. The method also keeps track of the decisions made and the actions taken in the process of managing inconsistencies

    Spectrally efficient transmit diversity scheme for differentially modulated multicarrier transmissions

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    Cyclic delay diversity is a simple, yet effective, transmit diversity scheme for multicarrier based transmissions employing coherent digital linear modulation schemes. It is shown that, for satisfactory operation, the scheme requires additional channel estimation overhead compared to single antenna and traditional space–time coded transmissions owing to the inherent increase in frequency selective fading. The authors analyse the additional channel estimation overhead requirement for a Hiperlan #2 style system with two transmit antennas operating in a NLOS indoor environment. The analysis shows that an additional overhead of 500% is required for the candidate system compared to a single antenna system. It is also shown that by employing differential modulation the channel estimation overhead can be eliminated with significant performance improvement compared to a system employing a practical channel estimation scheme. This novel combination, termed ‘differentially modulated cyclic delay diversity, is shown to yield a highly spectral efficient, yet simple transmit diversity solution for multi-carrier transmissions

    Dizzjunarju u kliem Ä¡did

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    Tiswir ta' kliem ġdid minn għeruq ta' verbi Maltin -Kull min hu mħarreġ fil-kitba jistenna li malli jibda jħaddem l-ilsien Malti jsib kotba letterarji u lingwistiċi li jgħinuh bħad-dizzjunarju.N/

    The relationship between infecting organisms and underlying structural anomalies in children with urinary tract infections

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    Introduction: Urinary tract infections (UTIs) are a common cause of morbidity in childhood with potential for renal scarring and reflux nephropathy which can lead to hypertension and end-stage renal failure. Aim: The aim of this study was to investigate the relationship between the infecting organism and any underlying anomalies of the urinary tract which may predispose to the development of infections and which may alter the management of children with UTIs. Methods and results: A total of 72 cases of UTI were recorded retrospectively (in- and outpatients), with ages ranging from 3 days to 48 months (mean 9.5, median 5 months). Fifty seven (79%) of patients had their first reported urinary tract infection under the age of 1 year.. Fifty eight (80.6%) were E. coli infections. These presented at an older age than non-E. coli infections. Investigations were abnormal in 31 (43%) cases. The mean age for first infection in patients with abnormal investigations was 7.7 months (median 2 months), younger than those with no renal tract abnormalities. Organisms other than E. coli were rarely found when no significant abnormalities were detected with investigation by US and MCUG and this was a statistically significant difference (p<0.001). Renal scarring was identified in 10 (13.9%) patients. Discussion: This study confirms that non-E. coli UTI is associated with underlying renal pathology and that early infections with any organism are more likely to be associated with underlying abnormalities. We also outline an algorithm based on the recent NICE 2007 guidelines which will be adopted by the Paediatric Department, Mater Dei Hospital for the investigation of UTI.peer-reviewe

    On the number of particles which a curved quantum waveguide can bind

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    We discuss the discrete spectrum of N particles in a curved planar waveguide. If they are neutral fermions, the maximum number of particles which the waveguide can bind is given by a one-particle Birman-Schwinger bound in combination with the Pauli principle. On the other hand, if they are charged, e.g., electrons in a bent quantum wire, the Coulomb repulsion plays a crucial role. We prove a sufficient condition under which the discrete spectrum of such a system is empty.Comment: a LateX file, 12 page

    Identifikasi Titik Kemacetan dan Alternatif Penanganannya di Kecamatan Pontianak Timur, Pontianak Selatan, Pontianak Tenggara

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    Growth and development of the city have an impact on the problem of traffic systems. The impact associated with the influence of road capacity and traffic volume, which can cause traffic congestion problem. From 3 districts who studied the East Pontianak, Pontianak South, Southeast Pontianak there are 9 point jam, and 2 of them experienced severe congestion that is the intersection of Jalan Sultan Hamid II - Jalan Imam snag - Way Hero - Road Tanjungpura and U-Turn at the next gas station OSO segment Ahmad Yani street. The purpose of this paper is to identify the point - the point of congestion and causes congestion in the districts East Pontianak, Pontianak South, and Southeast Pontianak so may submit management plans and programs of action plans that can be done to address the problem of traffic congestion in the district of East Pontianak, South Pontianak, Pontianak and Southeast for now. In this study, the data obtained by several agencies that BPS and POLRESTA city of Pontianak. The survey has been carried out, namely traffic volume survey conducted on Sunday (17 November 2013), on Monday (18 November 2013), in the morning at 6:00 a.m. to 9:00, lunch at 11:00 to 14:00, afternoon at 4:00 p.m. to 18:00 pm. The geometric survey conducted on Sunday (24 November 2013) .From these survey results taken 2 points were considered to be the most severe congestion that will be calculated and analyzed so that it will acquire the capacity and degree of saturation. The degree of saturation can be used as an indicator of the level of performance of an intersection and road segment. Where the degree of saturation can directly determine the performance of a road. Based on Indonesian Highway Capacity Manual for urban roads in 1997, requires the degree of saturation does not exceed 0.85. Based on the results obtained in 2013 the degree of saturation at Jalan Sultan Hamid II is 0.87, Jalan Imam Bonjol of 0.95, 0.70 at Jalan Pahlawan, Jalan Tanjungpura of 0.89 and a U-Turn at the next gas station OSO road Ahmad Yani direction Roundabout to Untan ie 0:56, 0:57 direction to the PCC that although the degree of saturation of <0.85 but the area can be said to be congested due to the long queue of vehicles that will pass through the U-Turn, disrupt traffic flow on the road Ahmad Yani. This indicates that in 2013 the 2 point of congestion experienced traffic problems. For those reasons, given the alternative solution is to operationalize back Public Transport Buses in particular, so as to reduce the degree of saturation in the region studied

    Understanding the in vivo Uptake Kinetics of a Phosphatidylethanolamine-binding Agent \u3csup\u3e99m\u3c/sup\u3eTc-Duramycin

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    Introduction 99mTc-Duramycin is a peptide-based molecular probe that binds specifically to phosphatidylethanolamine (PE). The goal was to characterize the kinetics of molecular interactions between 99mTc-Duramycin and the target tissue. Methods High level of accessible PE is induced in cardiac tissues by myocardial ischemia (30 min) and reperfusion (120 min) in Sprague–Dawley rats. Target binding and biodistribution of 99mTc-duramycin were captured using SPECT/CT. To quantify the binding kinetics, the presence of radioactivity in ischemic versus normal cardiac tissues was measured by gamma counting at 3, 10, 20, 60 and 180 min after injection. A partially inactivated form of 99mTc-Duramycin was analyzed in the same fashion. A compartment model was developed to quantify the uptake kinetics of 99mTc-Duramycin in normal and ischemic myocardial tissue. Results 99mTc-duramycin binds avidly to the damaged tissue with a high target-to-background radio. Compartment modeling shows that accessibility of binding sites in myocardial tissue to 99mTc-Duramycin is not a limiting factor and the rate constant of target binding in the target tissue is at 2.2 ml/nmol/min/g. The number of available binding sites for 99mTc-Duramycin in ischemic myocardium was estimated at 0.14 nmol/g. Covalent modification of D15 resulted in a 9-fold reduction in binding affinity. Conclusion 99mTc-Duramycin accumulates avidly in target tissues in a PE-dependent fashion. Model results reflect an efficient uptake mechanism, consistent with the low molecular weight of the radiopharmaceutical and the relatively high density of available binding sites. These data help better define the imaging utilities of 99mTc-Duramycin as a novel PE-binding agent

    DQLRFMG: Design of an Augmented Fusion of Deep Q Learning with Logistic Regression and Deep Forests for Multivariate Classification and Grading of Fruits

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    Accurate categorization and grading of fruits are essential in numerous fields, including agriculture, food processing, and distribution. This paper addresses the need for an advanced model capable of classifying and grading fruits more effectively than existing methods. Traditional approaches are limited by their lower precision, accuracy, recall, area under the curve (AUC), and delay. In order to overcome these obstacles, the proposed model combines the capabilities of Deep Q Learning (DQL) for classification and Logistic Regression (LR) with Deep Forests for fruit grading process. Three distinct datasets were used to evaluate the model: the Kaggle - Fruits 360 Dataset, the FRont Experimental System for High throughput plant phenotyping Datasets, and ImageNet samples. In multiple respects, comparative analysis demonstrates that the proposed model outperforms existing methods. Specifically, it achieves a remarkable 4.9% improvement in precision, 5.5% improvement in accuracy, 4.5% improvement in recall, 3.9% improvement in AUC, and an 8.5% reduction in delay levels. Utilizing the strengths of both DQL and LR with Deep Forests, the proposed model achieves its superior performance. DQL, a technique for reinforcement learning, provides the ability to learn and make decisions based on the feedback from the environment. By combining DQL and LR, the classification accuracy is improved, allowing for the precise identification of fruit varieties including Mango, Apple. Papaya, etc. In addition, Deep Forests, a novel framework for ensemble learning, is utilized for fruit grading. Deep Forests utilizes decision trees to effectively capture complex patterns in the data, allowing for dependable and robust fruit grading. Experimental findings indicate that the combination of DQL and LR with Deep Forests yields remarkable performance improvements in fruit classification and grading tasks. Improved precision, accuracy, recall, AUC, and delay indicate the model's superiority over existing methods. This research contributes to the field of fruit classification and grading by developing a sophisticated model that can support a variety of applications in the agriculture, food processing, and distribution industries

    Optical Imaging of Lipopolysaccharide-induced Oxidative Stress in Acute Lung Injury from Hyperoxia and Sepsis

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    Reactive oxygen species (ROS) have been implicated in the pathogenesis of many acute and chronic pulmonary disorders such as acute lung injury (ALI) in adults and bronchopulmonary dysplasia (BPD) in premature infants. Bacterial infection and oxygen toxicity, which result in pulmonary vascular endothelial injury, contribute to impaired vascular growth and alveolar simplification seen in the lungs of premature infants with BPD. Hyperoxia induces ALI, reduces cell proliferation, causes DNA damage and promotes cell death by causing mitochondrial dysfunction. The objective of this study was to use an optical imaging technique to evaluate the variations in fluorescence intensities of the auto-fluorescent mitochondrial metabolic coenzymes, NADH and FAD in four different groups of rats. The ratio of these fluorescence signals (NADH/FAD), referred to as NADH redox ratio (NADH RR) has been used as an indicator of tissue metabolism in injuries. Here, we investigated whether the changes in metabolic state can be used as a marker of oxidative stress caused by hyperoxia and bacterial lipopolysaccharide (LPS) exposure in neonatal rat lungs. We examined the tissue redox states of lungs from four groups of rat pups: normoxic (21% O2) pups, hyperoxic (90% O2) pups, pups treated with LPS (normoxic + LPS), and pups treated with LPS and hyperoxia (hyperoxic + LPS). Our results show that hyperoxia oxidized the respiratory chain as reflected by a ~ 31% decrease in lung tissue NADH RR as compared to that for normoxic lungs. LPS treatment alone or with hyperoxia had no significant effect on lung tissue NADH RR as compared to that for normoxic or hyperoxic lungs, respectively. Thus, NADH RR serves as a quantitative marker of oxidative stress level in lung injury caused by two clinically important conditions: hyperoxia and LPS exposure
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