Cryopreservation as a way to maintain extracorporeal photopheresis regimen for GvHD treatment while circumventing patient temporary inability to undergo apheresis

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The Giant Radio Array for Neutrino Detection (GRAND):Science and design

International audienceThe Giant Radio Array for Neutrino Detection (GRAND) is a planned large-scale observatory of ultra-high-energy (UHE) cosmic particles, with energies exceeding 10$^{8}$ GeV. Its goal is to solve the long-standing mystery of the origin of UHE cosmic rays. To do this, GRAND will detect an unprecedented number of UHE cosmic rays and search for the undiscovered UHE neutrinos and gamma rays associated to them with unmatched sensitivity. GRAND will use large arrays of antennas to detect the radio emission coming from extensive air showers initiated by UHE particles in the atmosphere. Its design is modular: 20 separate, independent sub-arrays, each of 10000 radio antennas deployed over 10000 km$^{2}$. A staged construction plan will validate key detection techniques while achieving important science goals early. Here we present the science goals, detection strategy, preliminary design, performance goals, and construction plans for GRAND

Science and Design for the Giant Radio Array for Neutrino Detection

International audienceGRAND is a planned large-scale observatory of ultra-high energy (UHE) cosmic messengers with energies exceeding 10⁸ GeV. The ultimate goal is to solve the long-standing mystery of the origin of UHE cosmic rays. Three key features of GRAND will make this possible: its large exposure, sub-degree angular resolution, and sensitivity to UHE particles

Science and Design for the Giant Radio Array for Neutrino Detection

International audienceGRAND is a planned large-scale observatory of ultra-high energy (UHE) cosmic messengers with energies exceeding 10⁸ GeV. The ultimate goal is to solve the long-standing mystery of the origin of UHE cosmic rays. Three key features of GRAND will make this possible: its large exposure, sub-degree angular resolution, and sensitivity to UHE particles

Science and Design for the Giant Radio Array for Neutrino Detection

International audienceGRAND is a planned large-scale observatory of ultra-high energy (UHE) cosmic messengers with energies exceeding 10⁸ GeV. The ultimate goal is to solve the long-standing mystery of the origin of UHE cosmic rays. Three key features of GRAND will make this possible: its large exposure, sub-degree angular resolution, and sensitivity to UHE particles