1,134 research outputs found
Cyberlaundering: The Risks, the Responses
This Article discusses the potential use of electronic cash for money laundering and possible government responses to the problem. Parts I and II provide an overview of electronic cash. Part III explores the effects that electronic cash can have on money laundering. Part IV explains through a series of hypotheticals how cyberlaundering can occur. Part V analyzes the federal government\u27s response to the threat of money laundering with electronic cash. Part VI concludes the Article with suggestions
Order statistics and heavy-tail distributions for planetary perturbations on Oort cloud comets
This paper tackles important aspects of comets dynamics from a statistical
point of view. Existing methodology uses numerical integration for computing
planetary perturbations for simulating such dynamics. This operation is highly
computational. It is reasonable to wonder whenever statistical simulation of
the perturbations can be much more easy to handle. The first step for answering
such a question is to provide a statistical study of these perturbations in
order to catch their main features. The statistical tools used are order
statistics and heavy tail distributions. The study carried out indicated a
general pattern exhibited by the perturbations around the orbits of the
important planet. These characteristics were validated through statistical
testing and a theoretical study based on Opik theory.Comment: 9 pages, 12 figures, submitted for publication in Astronomy and
Astrophysic
Equilibrium Sampling From Nonequilibrium Dynamics
We present some applications of an Interacting Particle System (IPS)
methodology to the field of Molecular Dynamics. This IPS method allows several
simulations of a switched random process to keep closer to equilibrium at each
time, thanks to a selection mechanism based on the relative virtual work
induced on the system. It is therefore an efficient improvement of usual
non-equilibrium simulations, which can be used to compute canonical averages,
free energy differences, and typical transitions paths
Epitaxial Growth Kinetics with Interacting Coherent Islands
The Stranski-Krastanov growth kinetics of undislocated (coherent)
3-dimensional islands is studied with a self-consistent mean field rate theory
that takes account of elastic interactions between the islands. The latter are
presumed to facilitate the detachment of atoms from the islands with a
consequent decrease in their average size. Semi-quantitative agreement with
experiment is found for the time evolution of the total island density and the
mean island size. When combined with scaling ideas, these results provide a
natural way to understand the often-observed initial increase and subsequent
decrease in the width of the coherent island size distribution.Comment: 4 pages, 4 figure
Missed opportunities for tuberculosis prevention among patients accessing a UK HIV service.
United Kingdom guidelines recommend screening for and treatment of latent tuberculosis infection (LTBI) in HIV-positive patients at high risk of active tuberculosis (TB) disease, but implementation is suboptimal. We investigated potential missed opportunities to identify and treat LTBI among HIV-positive patients accessing a large HIV outpatient service in London. Case records of all adult patients attending our service for HIV care diagnosed with active TB between 2011 and 2015 were reviewed to determine whether they met criteria for LTBI screening and whether screening was undertaken. Twenty-five patients were treated for TB. Of 15 (60%) patients who started TB treatment ≥6 months after HIV diagnosis, 14 (93%) met UK guideline-recommended criteria for LTBI screening and treatment; only one (7%) had been screened for LTBI. Eight of these 15 (53%) patients had additional risk factors for TB which are not reflected in current UK guidelines. Of 15 patients treated for TB ≥6 months after diagnosis of HIV, 14 (93%) had not been screened for LTBI, suggesting missed opportunities for TB prevention. People living with HIV may benefit from a broader approach to LTBI screening which takes into account additional recognised TB risk factors and ongoing TB exposure
Rotation-assisted wet-spinning of UV-cured gelatin fibres and nonwovens
Photoinduced network formation is an attractive strategy for designing water-insoluble gelatin fibres as medical device building blocks and for enabling late-stage property customisation. However, mechanically competent, long-lasting filaments are still hard to realise with current photoactive, e.g. methacrylated, gelatin systems due to inherent spinning instability and restricted coagulation capability. To explore this challenge, we present a multiscale approach combining the synthesis of 4-vinylbenzyl chloride (4VBC)-functionalised gelatin (Gel-4VBC) with a voltage-free spinning and UV-curing process so that biopolymer networks in the form of either individual fibres or nonwovens could be successfully manufactured. In comparison with state-of-the-art methacrylated gelatin, the mechanical properties of UV-cured Gel-4VBC fibres were readily modulated by adjustment of coagulation conditions, so that an ultimate tensile strength and strain at break of 25 ± 4–74 ± 3 MPa and 1.7 ± 0.3–8.6 ± 0.5% were measured, respectively. The sequential functionalisation/spinning route proved to be highly scalable, so that one-step spun-laid formation of fibroblast-friendly nonwoven fabrics was successfully demonstrated with wet-spun Gel-4VBC fibres. The presented approach could be exploited to generate a library of gelatin building blocks tuneable from the molecular to the macroscopic level to deliver computer-controlled extrusion of fibres and nonwovens according to defined clinical applications
Identifying Geographic Areas at Risk of Soil-transmitted Helminthes Infection Using Remote Sensing and Geographical Information Systems: Boaco, Nicaragua as a Case Study
Several types of intestinal nematodes, that can infect humans and specially school-age children living in poverty, develop part of their life cycle in soil. Presence and survival of these parasites in the soil depend on given environmental characteristics like temperature and moisture that can be inferred with remote sensing (RS) technology. Prevalence of diseases caused by these parasitic worms can be controlled and even eradicated with anthelmintic drug treatments and sanitation improvement. Reliable and updated identification of geographic areas at risk is required to implement effective public health programs; to calculate amount of drug required and to distribute funding for sanitation projects. RS technology and geographical information systems (GIS) will be used to analyze for associations between in situ prevalence and remotely sensed data in order to establish RS proxies of environmental parameters that indicate the presence of these parasits. In situ data on helminthisasis will be overlaid over an ecological map derived from RS data using ARC Map 9.3 (ESRI). Temperature, vegetation, and distance to bodies of water will be inferred using data from Moderate-Resolution Imaging Spectroradiometer (MODIS) and Landsat TM and ETM+. Elevation will be estimated with data from The Shuttle Radar Topography Mission (SRTM). Prevalence and intensity of infections are determined by parasitological survey (Kato Katz) of children enrolled in rural schools in Boaco, Nicaragua, in the communities of El Roblar, Cumaica Norte, Malacatoya 1, and Malacatoya 2). This study will demonstrate the importance of an integrated GIS/RS approach to define clusters and areas at risk. Such information will help to the implementation of time and cost efficient control programs and sanitation efforts
Diagnostic rates and treatment of dementia before and after launch of a national dementia policy: an observational study using English national databases.
To assess the 2009 National Dementia Strategy's (NDS) impact on dementia diagnosis and treatment
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