Nonlinear wave interaction and spin models in the MHD regime

Here we consider the influence on the electron spin in the MHD regime. Recently developed models which include spin-velocity correlations are taken as a starting point. A theoretical argument is presented, suggesting that in the MHD regime a single fluid electron model with spin correlations is equivalent to a model with spin-up and spin-down electrons constituting different fluids, but where the spin-velocity correlations are omitted. Three wave interaction of 2 shear Alfven waves and a compressional Alfven wave is then taken as a model problem to evaluate the asserted equivalence. The theoretical argument turns out to be supported, as the predictions of the two models agree completely. Furthermore, the three wave coupling coefficients obey the Manley-Rowe relations, which give further support to the soundness of the models and the validity of the assumptions made in the derivation. Finally we point out that the proposed two-fluid model can be incorporated in standard Particle-In-Cell schemes with only minor modifications.Comment: 8 page

High Energy Neutrinos and Photons from Curvature Pions in Magnetars

We discuss the relevance of the curvature radiation of pions in strongly magnetized pulsars or magnetars, and their implications for the production of TeV energy neutrinos detectable by cubic kilometer scale detectors, as well as high energy photons.Comment: 19 pages, 4 figures, to appear in JCA

Strategies to improve retention in randomised trials: a Cochrane systematic review and meta-analysis

Objective: To quantify the effect of strategies to improve retention in randomised trials.<p></p> Design: Systematic review and meta-analysis.<p></p> Data sources Sources searched: MEDLINE, EMBASE, PsycINFO, DARE, CENTRAL, CINAHL, C2-SPECTR, ERIC, PreMEDLINE, Cochrane Methodology Register, Current Controlled Trials metaRegister, WHO trials platform, Society for Clinical Trials (SCT) conference proceedings and a survey of all UK clinical trial research units.<p></p> Review: methods Included trials were randomised evaluations of strategies to improve retention embedded within host randomised trials. The primary outcome was retention of trial participants. Data from trials were pooled using the fixed-effect model. Subgroup analyses were used to explore the heterogeneity and to determine whether there were any differences in effect by the type of strategy.<p></p> Results: 38 retention trials were identified. Six broad types of strategies were evaluated. Strategies that increased postal questionnaire responses were: adding, that is, giving a monetary incentive (RR 1.18; 95% CI 1.09 to 1.28) and higher valued incentives (RR 1.12; 95% CI 1.04 to 1.22). Offering a monetary incentive, that is, an incentive given on receipt of a completed questionnaire, also increased electronic questionnaire response (RR 1.25; 95% CI 1.14 to 1.38). The evidence for shorter questionnaires (RR 1.04; 95% CI 1.00 to 1.08) and questionnaires relevant to the disease/condition (RR 1.07; 95% CI 1.01 to 1.14) is less clear. On the basis of the results of single trials, the following strategies appeared effective at increasing questionnaire response: recorded delivery of questionnaires (RR 2.08; 95% CI 1.11 to 3.87); a ‘package’ of postal communication strategies (RR 1.43; 95% CI 1.22 to 1.67) and an open trial design (RR 1.37; 95% CI 1.16 to 1.63). There is no good evidence that the following strategies impact on trial response/retention: adding a non-monetary incentive (RR=1.00; 95% CI 0.98 to 1.02); offering a non-monetary incentive (RR=0.99; 95% CI 0.95 to 1.03); ‘enhanced’ letters (RR=1.01; 95% CI 0.97 to 1.05); monetary incentives compared with offering prize draw entry (RR=1.04; 95% CI 0.91 to 1.19); priority postal delivery (RR=1.02; 95% CI 0.95 to 1.09); behavioural motivational strategies (RR=1.08; 95% CI 0.93 to 1.24); additional reminders to participants (RR=1.03; 95% CI 0.99 to 1.06) and questionnaire question order (RR=1.00, 0.97 to 1.02). Also based on single trials, these strategies do not appear effective: a telephone survey compared with a monetary incentive plus questionnaire (RR=1.08; 95% CI 0.94 to 1.24); offering a charity donation (RR=1.02, 95% CI 0.78 to 1.32); sending sites reminders (RR=0.96; 95% CI 0.83 to 1.11); sending questionnaires early (RR=1.10; 95% CI 0.96 to 1.26); longer and clearer questionnaires (RR=1.01, 0.95 to 1.07) and participant case management by trial assistants (RR=1.00; 95% CI 0.97 to 1.04).<p></p> Conclusions: Most of the trials evaluated questionnaire response rather than ways to improve participants return to site for follow-up. Monetary incentives and offers of monetary incentives increase postal and electronic questionnaire response. Some strategies need further evaluation. Application of these results would depend on trial context and follow-up procedures.<p></p&gt

Use of strategies to improve retention in primary care randomised trials: a qualitative study with in-depth interviews

Objective To explore the strategies used to improve retention in primary care randomised trials.<p></p> Design Qualitative in-depth interviews and thematic analysis.<p></p> Participants 29 UK primary care chief and principal investigators, trial managers and research nurses.<p></p> Methods In-depth face-to-face interviews.<p></p> Results Primary care researchers use incentive and communication strategies to improve retention in trials, but were unsure of their effect. Small monetary incentives were used to increase response to postal questionnaires. Non-monetary incentives were used although there was scepticism about the impact of these on retention. Nurses routinely used telephone communication to encourage participants to return for trial follow-up. Trial managers used first class post, shorter questionnaires and improved questionnaire designs with the aim of improving questionnaire response. Interviewees thought an open trial design could lead to biased results and were negative about using behavioural strategies to improve retention. There was consensus among the interviewees that effective communication and rapport with participants, participant altruism, respect for participant's time, flexibility of trial personnel and appointment schedules and trial information improve retention. Interviewees noted particular challenges with retention in mental health trials and those involving teenagers.<p></p> Conclusions The findings of this qualitative study have allowed us to reflect on research practice around retention and highlight a gap between such practice and current evidence. Interviewees describe acting from experience without evidence from the literature, which supports the use of small monetary incentives to improve the questionnaire response. No such evidence exists for non-monetary incentives or first class post, use of which may need reconsideration. An exploration of barriers and facilitators to retention in other research contexts may be justified.<p></p&gt

Harmonic Love wave devices for biosensing applications

Simultaneous operation of a Love wave biosensor at the fundamental frequency and third harmonic, including the optimisation of IDT metallisation thickness, has been investigated. Data is presented showing a sequence of deposition and removal of a model mass layer of palmitoyl-oleoyl-sn-glycerophosphocholine (POPC) vesicles while frequency hopping between 110 and 330 MH

A new beamline for laser spin-polarization at ISOLDE

A beamline dedicated to the production of laser-polarized radioactive beams has been constructed at ISOLDE, CERN. We present here different simulations leading to the design and construction of the setup, as well as technical details of the full setup and examples of the achieved polarizations for several radioisotopes. Beamline simulations show a good transmission through the entire line, in agreement with observations. Simulations of the induced nuclear spin-polarization as a function of atom-laser interaction length are presented for $^{26,28}$Na, [1] and for $^{35}$Ar, which is studied in this work. Adiabatic spin rotation of the spin-polarized ensemble of atoms, and how this influences the observed nuclear ensemble polarization, are also performed for the same nuclei. For $^{35}$Ar, we show that multiple-frequency pumping enhances the ensemble polarization by a factor 1.85, in agreement with predictions from a rate equations model. [1] J. Phys. G: Nucl. Part. Phys./174408400

e±e^\pm Excesses in the Cosmic Ray Spectrum and Possible Interpretations

The data collected by ATIC, PPB-BETS, FERMI-LAT and HESS all indicate that there is an electron/positron excess in the cosmic ray energy spectrum above $\sim$ 100 GeV, although different instrumental teams do not agree on the detailed spectral shape. PAMELA also reported a clear excess feature of the positron fraction above several GeV, but no excess in anti-protons. Here we review the observational status and theoretical models of this interesting observational feature. We pay special attention to various physical interpretations proposed in the literature, including modified supernova remnant models for the $e^\pm$ background, new astrophysical sources, and new physics (the dark matter models). We suggest that although most models can make a case to interpret the data, with the current observational constraints the dark matter interpretations, especially those invoking annihilation, require much more exotic assumptions than some astrophysical interpretations. Future observations may present some ``smoking-gun'' observational tests to differentiate among different models and to identify the correct interpretation to the phenomenon.Comment: 48 pages, including 10 figures and 1 tabel. Invited review to be published in IJMP

Chandra Phase-Resolved X-ray Spectroscopy of the Crab Pulsar II

We present a new study of the X-ray spectral properties of the Crab Pulsar. The superb angular resolution of the Chandra X-ray Observatory enables distinguishing the pulsar from the surrounding nebulosity. Analysis of the spectrum as a function of pulse phase allows the least-biased measure of interstellar X-ray extinction due primarily to photoelectric absorption and secondarily to scattering by dust grains in the direction of the Crab Nebula. We modify previous findings that the line-of-sight to the Crab is under-abundant in oxygen and provide measurements with improved accuracy and less bias. Using the abundances and cross sections from Wilms, Allen & McCray (2000) we find [O/H] = $(5.28 \pm 0.28)\times10^{-4}$ ($4.9 \times10^{-4}$ is solar abundance). We also measure for the first time the impact of scattering of flux out of the image by interstellar grains. We find $\tau_{\rm scat} = 0.147 \pm 0.043$. Analysis of the spectrum as a function of pulse phase also measures the X-ray spectral index even at pulse minimum --- albeit with increasing statistical uncertainty. The spectral variations are, by and large, consistent with a sinusoidal variation. The only significant variation from the sinusoid occurs over the same phase range as some rather abrupt behavior in the optical polarization magnitude and position angle. We compare these spectral variations to those observed in Gamma-rays and conclude that our measurements are both a challenge and a guide to future modeling and will thus eventually help us understand pair cascade processes in pulsar magnetospheres. The data were also used to set new, and less biased, upper limits to the surface temperature of the neutron star for different models of the neutron star atmosphere.Comment: 32 pages, 6 figures submitted to the Astrophysical journa

Sex-specific effects of nutritional supplements in infants born early or small: protocol for an individual participant data meta-analysis (ESSENCE IPD-MA).

INTRODUCTION: Preterm and small for gestational age (SGA) infants are at increased risk of poor growth, disability and delayed development. While growing up they are also at increased risk of obesity, diabetes and later heart disease. The risk of such adverse outcomes may be altered by how preterm and SGA infants are fed after birth. Faltering postnatal growth is common due to failure to achieve recommended high energy and protein intakes, and thus preterm and SGA infants are often provided with supplemental nutrition soon after birth. Enhanced nutrition has been associated with improved early growth and better cognitive development. However, limited evidence suggests that faster growth may increase the risk for later adiposity, metabolic and cardiovascular disease, and that such risks may differ between girls and boys. METHODS AND ANALYSIS: We will search Ovid MEDLINE, Embase, Cochrane CENTRAL, Cochrane Database of Systematic Reviews, controlled-trials.com, ClinicalTrials.gov and anzctr.org.au for randomised trials that studied the effects of macronutrient supplements for preterm and SGA infants on (i) developmental and metabolic and (ii) growth outcomes after hospital discharge. The outcomes will be (i) cognitive impairment and metabolic risk (co-primary) and (ii) body mass index. Individual participant data (IPD) from all available trials will be included using an intention-to-treat approach. A one-stage procedure for IPD meta-analysis (MA) will be used, accounting for clustering of participants within studies. Exploratory subgroup analyses will further investigate sources of heterogeneity, including sex and size of infants, different timing, duration and type of supplements. ETHICS AND DISSEMINATION: This IPD-MA is approved by the University of Auckland Human Participants Ethics Committee (reference number: 019874). Individual studies have approval from relevant local ethics committees. Results will be disseminated in a peer-reviewed journal and presented at international conferences. PROSPERO REGISTRATION NUMBER: CRD42017072683

Dense stellar matter with trapped neutrinos under strong magnetic fields

We investigate the effects of strong magnetic fields on the equation of state of dense stellar neutrino-free and neutrino-trapped matter. Relativistic nuclear models both with constant couplings (NLW) and with density dependent parameters (DDRH) and including hyperons are considered . It is shown that at low densities neutrinos are suppressed in the presence of the magnetic field. The magnetic field reduces the strangeness fraction of neutrino-free matter and increases the strangeness fraction of neutrino-trapped matter. The mass-radius relation of stars described by these equations of state are determined. The magnetic field makes the overall equation of state stiffer and the stronger the field the larger the mass of maximum mass star and the smaller the baryon density at the center of the star. As a consequence in the presence of strong magnetic fields the possibility that a protoneutron star evolves to a blackhole is smaller.Comment: 18 pages, 13 figures, 5 tables, submitted to J. Phys.