340 research outputs found

    Exact Solutions of a (2+1)-Dimensional Nonlinear Klein-Gordon Equation

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    The purpose of this paper is to present a class of particular solutions of a C(2,1) conformally invariant nonlinear Klein-Gordon equation by symmetry reduction. Using the subgroups of similitude group reduced ordinary differential equations of second order and their solutions by a singularity analysis are classified. In particular, it has been shown that whenever they have the Painlev\'e property, they can be transformed to standard forms by Moebius transformations of dependent variable and arbitrary smooth transformations of independent variable whose solutions, depending on the values of parameters, are expressible in terms of either elementary functions or Jacobi elliptic functions.Comment: 16 pages, no figures, revised versio

    Palaeotethys-related sediments of the Karaburun Peninsula, western Turkey: constraints on provenance and stratigraphy from detrital zircon geochronology

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    Detrital zircon U–Pb geochronology of 15 Late Palaeozoic to Early Mesozoic siliciclastic sandstones from the Karaburun Peninsula in western Turkey determines maximum sedimentation ages, identifies possible source areas, and anchors the study area within the Palaeotethyan realm. Siliciclastic sandstones yielded ages from Triassic to Archean with major input from Palaeozoic to Neoproterozoic sources and very few Mesoproterozoic zircons. The youngest age groups set the new limit of the maximum depositional ages to Late Carboniferous–Early Permian for the Küçükbahçe and Dikendağı formations. Detrital zircons from Triassic sandstones are mainly Neoproterozoic and Palaeozoic in age. Zircons from the Scythian–Anisian Gerence Formation are predominantly Devonian and Carboniferous in age, while also Permian and Triassic zircon grains occur in the Carnian–Rhaetian Güvercinlik Formation. According to the zircon age populations and the data available from possible source regions, the Karaburun siliciclastic sediments, with the exception of two samples from the Dikendağı Formation, record sediment supply from units located at the southern margin of Eurasia during Late Palaeozoic and Early Mesozoic times. This interpretation is in agreement with palaeotectonic reconstructions for the closely related Greek islands of Chios and Inousses. The presence of Devonian accompanied by Carboniferous zircons in some of the Karaburun samples reveals similarities with Karakaya Complex sandstones of the Sakarya Zone in NW Turkey

    Evolution of the Palaeotethys in the Eastern Mediterranean: A multi-method approach to unravel the age, provenance and tectonic setting of the Upper Palaeozoic Konya Complex and its Mesozoic cover sequence (south-central Turkey)

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    Thirteen siliciclastic sediments from the Upper Palaeozoic Konya Complex and its Mesozoic cover were studied by a multi-method approach combining thin-section petrography, bulk-rock geochemistry, mineral chemistry of rutile, and U–Pb geochronology of detrital zircons. Provenance sensitive data of samples from the Upper Palaeozoic Halıcı Formation indicate sediment supply from mainly low- to medium-grade metamorphosed sedimentary rocks of felsic character, while contribution from volcanic rocks was rare. The detrital zircon record of sediments from the Halıcı Formation documents sediment supply from different sources and excludes a similar provenance. Some samples show great similarities with Palaeozoic sandstones from the cover sequence of the Saharan Metacraton and the Arabian–Nubian Shield, while the other samples indicate a provenance that must be sought in units with a southern Eurasian affinity. The upper limit for sediment deposition in the Halıcı Formation is mostly constrained by Early Palaeozoic zircon populations, however, sediment accumulation in Pennsylvanian–Cisuralian time is more likely, contemporaneously with the Upper Palaeozoic succession on the Karaburun Peninsula (western Turkey). The provenance of sediments from the Upper Triassic Ardıçlı Formation remains enigmatic, but the source should be sought nonetheless in units close to the depositional site. In any case, detrital zircon age spectra and compositional data exclude recycling of underlying rock units (i.e. Halıcı Formation). Overall, our new provenance data reveal great similarities between the Konya Complex and comparable units (Chios, Karaburun) but also highlight distinct differences in terms of sediment composition and provenance

    Disseminated Fusarium oxysporum Infection in Hemophagocytic Lymphohistiocytosis

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    Abstract : The portal of entry of disseminated Fusarium spp. infections is still not clearly defined. We report on a disseminated Fusarium oxysporum infection occurring during a long period of severe neutropenia in a child with hemophagocytic lymphohistiocytosis. A nasogastric feeding tube was the possible source of entry of the fungu

    Primary Molar Pulpotomies with Different Hemorrhage Control Agents and Base Materials: A Randomized Clinical Trial

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    Objective: To evaluate the clinical and radiographical success of primary molar pulpotomies which used 15.5% ferric sulfate (FS) or 1.25% sodium hypochlorite (NaOCl) for hemostasis and zinc oxide-eugenol (ZOE) and calcium hydroxide (CH) pastes as base materials. Methods: In 29 healthy children, 80 primary molars were randomly allocated to one of the study groups: Group 1: FS-ZOE, Group 2: FS-CH, Group 3: NaOCl-ZOE, and Group 4: NaOCl-CH. After hemostasis with the respective solutions, pulp stumps and floor of the pulp chambers were covered with either ZOE or CH pastes. All teeth were restored with stainless steel crowns. Follow-up examinations were carried out at 1, 3, 6, and 12 months. Results: One tooth in Group 1 and two teeth in Group 4 were extracted because of pain and periapial pathosis at sixth month. After 12 months, clinical success rates of pulpotomies in Groups 1-4 were 95%, 100%, 100%, and 89.5%, respectively. The differences were not significant (P = 0.548). Radiographic success rates for Groups 1-4 were 80%, 88.9%, 78.9%, and 84.2%, respectively. No statistically significant difference was found (P = 0.968). Pain on percussion was the most observed clinical finding. However, internal root resorption was the most common radiological finding and it was observed significantly more in mandibular primary molars (P \u3c 0.05). Conclusion: Both ZOE and CH can be preferred as base materials after hemostasis achieved by the use of 15.5% FS or 1.25% NaOCl in primary tooth pulpotomy

    Provenance and tectonic setting of Carboniferous–Triassic sandstones from the Karaburun Peninsula, western Turkey: A multi-method approach with implications for the Palaeotethys evolution

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    Carboniferous–Triassic siliciclastic sediments of the Karaburun Peninsula in western Turkey were studied to unravel their provenance and the tectonic setting of depositional basins within the Palaeotethyan realm. A set of complementary techniques including petrography, bulk-rock geochemistry and single-grain analysis of rutile, garnet and chrome spinel were applied to provide a diverse dataset for testing existing palaeotectonic models using both, established and recently published diagrams. We show that tectonic discrimination diagrams of siliciclastic sediments based on major and trace element whole-rock geochemical data do yield ambiguous results and are only partly in accordance with regional geological events. Chondrite-normalised REE patterns of Upper Palaeozoic samples are characterised by enrichment of LREE and a flat trend towards HREE. The degree of fractionation allows for discrimination between sandstones of Karaburun (LaN/YbN = 8.00–14.79) and adjacent Greek islands of Chios (5.82–9.23) and Inousses (7.40–9.95). Petrographic observations and compositional data from single-grain analysis indicate significant supply from low- to medium-grade metamorphic rocks of generally felsic character and minor input of (ultra)mafic detritus. Detrital chrome spinels in the Lower Triassic Gerence Formation are different in composition and shape compared to chrome spinels in Carboniferous–Permian sandstones. They were derived from a very proximal source and exhibit variable, but generally high Cr- and Mg-numbers, consistent with chrome spinels from podiform chromitites that have been formed in an intra-oceanic back-arc setting above a supra-subduction zone. We conclude that most of the Carboniferous–Triassic successions were deposited along the southern active margin of Eurasia in a continental-arc environment during the time period when Palaeotethys diminished in size and finally vanished. Large volumes of detritus were probably derived from rock units located in the present-day Balkan region and the Sakarya Zone, or equivalent successions that are not present anymore

    Effective early termination techniques for text similarity join operator

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    Bu çalışma, 26-28 Ekim 2005 tarihleri arasında İstanbul[Türkiye]'da düzenlenen 20. International Symposium on Computer and Information Sciences'da bildiri olarak sunulmuştur.Text similarity join operator joins two relations if their join attributes are textually similar to each other, and it has a variety of application domains including integration and querying of data from heterogeneous resources; cleansing of data; and mining of data. Although, the text similarity join operator is widely used, its processing is expensive due to the huge number of similarity computations performed. In this paper, we incorporate some short cut evaluation techniques from the Information Retrieval domain, namely Harman, quit, continue, and maximal similarity filter heuristics, into the previously proposed text similarity join algorithms to reduce the amount of similarity computations needed during the join operation. We experimentally evaluate the original and the heuristic based similarity join algorithms using real data obtained from the DBLP Bibliography database, and observe performance improvements with continue and maximal similarity filter heuristics.Inst Elec & Elect Engineers, Turkey SectBoğaziçi Üniversites

    Survival and associated factors in 268 adults with Pompe disease prior to treatment with enzyme replacement therapy

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    Background: Pompe disease is a rare lysosomal storage disorder characterized by muscle weakness and wasting. The majority of adult patients have slowly progressive disease, which gradually impairs mobility and respiratory function and may lead to wheelchair and ventilator dependency. It is as yet unknown to what extent the disease reduces the life span of these patients. Our objective was to determine the survival of adults with P

    Lymphoid Enhancer Factor-1 Links Two Hereditary Leukemia Syndromes through Core-binding Factor α Regulation of ELA2

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    Two hereditary human leukemia syndromes are severe congenital neutropenia (SCN), caused by mutations in the gene ELA2, encoding the protease neutrophil elastase, and familial platelet disorder with acute myelogenous leukemia (AML), caused by mutations in the gene AML1, encoding the transcription factor core-binding factor α (CBFα). In mice, CBFα regulates the expression of ELA2, suggesting a common link for both diseases. However, gene-targeted mouse models have failed to reproduce either human disease, thus prohibiting further in vivo studies in mice. Here we investigate CBFα regulation of the human ELA2 promoter, taking advantage of bone marrow obtained from patients with either illness. In particular, we have identified novel ELA2 promoter substitutions (-199 C to A) within a potential motif for lymphoid enhancer factor-1 (LEF-1), a transcriptional mediator of Wnt/β-catenin signaling, in SCN patients. The LEF-1 motif lies adjacent to a potential CBFα binding site that is in a different position in human compared with mouse ELA2. We find that LEF-1 and CBFα co-activate ELA2 expression. In vitro, the high mobility group domain of LEF-1 interacts with the runt DNA binding and proline-, serine-, threonine-rich activation domains of CBFα. ELA2 transcript levels are up-regulated in bone marrow of an SCN patient with the -199 C to A substitution. Conversely, a mutation of the CBFα activation domain, found in a patient with familial platelet disorder with AML, fails to stimulate the ELA2 promoter in vitro, and bone marrow correspondingly demonstrates reduced ELA2 transcript. Observations in these complementary patients indicate that LEF-1 cooperates with CBFα to activate ELA2 in vivo and also suggest the possibility that up-regulating promoter mutations can contribute to SCN. Two hereditary AML predisposition syndromes may therefore intersect via LEF-1, potentially linking them to more generalized cancer mechanisms
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