Slaughter weight rather than sex affects carcass cuts and tissue composition of Bisaro pigs

Carcass cuts and tissue composition were assessed in Bisaro pigs (n=64) from two sexes (31 gilts and 33 entire males) reared until three target slaughter body-weights (BW) means: 17 kg, 32 kg, and 79 kg. Dressing percentage and backfat thickness increased whereas carcass shrinkage decreased with increasing BW. Slaughter weight affected most of the carcass cut proportions, except shoulder and thoracic regions. Bone proportion decreased linearly with increasing slaughter BW, while intermuscular and subcutaneous adipose tissue depots increased concomitantly. Slaughter weight increased the subcutaneous adipose tissue proportion but this impaired intramuscular and intermuscular adipose tissues in the loin primal. The sex of the pigs minimally affected the carcass composition, as only the belly weight and the subcutaneous adipose tissue proportions were greater in gilts than in entire males. Light pigs regardless of sex are recommended to balance the trade-offs between carcass cuts and their non-edible compositional outcomes.Work included in the Portuguese PRODER research Project BISOPORC – Pork extensive production of Bísara breed, in two alternative systems: fattening on concentrate vs chesnut, Project PRODER SI I&DT Medida 4.1 “Cooperação para a Inovação”. The authors are grateful to Laboratory of Carcass and Meat Quality of Agriculture School of Polytechnic Institute of Bragança ‘Cantinho do Alfredo’. The authors are members of the MARCARNE network, funded by CYTED (ref. 116RT0503).info:eu-repo/semantics/publishedVersio

An inherited nonsense R1645X mutation in neuronal sodium channel 1-subunit gene in a Turkish patient with severe myoclonic epilepsy of infancy

PubMed ID: 19809937Severe myoclonic epilepsy of infancy (SMEI) is a well-known catastrophic epileptic syndrome. Several mutations of the sodium channel alpha 1 subunit (SCN1A) gene were reported in patients with SMEI. Most of the mutations were de novo. Inherited truncating mutations are very rare. Here a patient with a new nonsense mutation (c.4933 C>T; p.R1645X) of the gene is described. This mutation was inherited from the father who had only febrile seizures during childhood. © Georg Thieme Verlag KG Stuttgart New York

Extreme delta brush activity: Could it be a marker for early diagnosis and prognosis of anti-nmda (n-methyl-d-aspartate) encephalitis? [Aşırı delta brush aktivitesi anti-nmda (N-metil-d-aspartat) ensefalitinde erken tanı ve prognoz için bir belirteç olabilir mi?]

2-s2.0-85088966607Autoimmune encephalitis should be excluded in unexplained en-cephalitis. A significant portion of autoimmune encephalitis in childhood is anti-NMDA encephalitis. However, neuroimaging and routine diagnostic tests are inadequate, diagnosis sholud be confirmed by the demonstration of autoantibodies. The treatment may be delay in this process. Extreme delta brush waves are unique electroencephalography pattern, seen in some of An-ti-NMDA encephalitis, useful for early diagnosis. Extreme delta brush activity is associated with prolonged hospitalization and illness. Despite of these, the specificity and sensitivity of this pattern is not-known clearly. We present a five years old boy with the loss of consciousness, involuntary movements, intermittant gen-eralized tonic clonic seizures and extreme delta brush activity in electroencephalography. © 2019 by Turkish Pediatric Association

A neurobrucellosis case presenting with bilateral facial nerve palsy and peripheral neuropathy

Neurobrucellosis is an uncommon complication of pediatric brucellosis. Direct invasion of the central nervous system occurs in about 5% of the cases of Brucella melitensis infection. Meningitis or meningoencephalitis are the most common manifestations. Neurobrucellosis may rarely affect second, third, sixth, seventh and the eighth cranial nerves. Peripheral nerve involvement is also rarely seen in pediatric neurobrucellosis. Here we reported is a twelve years old girl presented with bilateral peripheral facial nerve palsy and peripheral neuropathy. This case is an unusual presentation of neurobrucellosis in pediatric population. Our report emphasizes that neurobrucellosis should be kept in mind in the cases with atypical neurologic manifestations in endemic regions. © 2015 by Türkiye Klinikleri

Correlative value of magnetic resonance imaging for neurodevelopmental outcome in periventricular leukomalacia

PubMed ID: 15540633The aim of this study was to evaluate the correlative value of magnetic resonance imaging (MRI) in children with periventricular leukomalacia (PVL) for neurodevelopmental outcome. MRI examinations of 89 children (46 males, 43 females) with PVL (median age 4y, range 1 to 14y) were reevaluated. PVL was graded as follows: grade I, unilateral or bilateral areas of periventricular hyperintensity (1-3); grade II, hyperintensity more than 3; grade III, hyperintense lesions more than 3 and ventricular wall irregularity; grade IV, diffuse PVL and ventricular dilatation. Localizations of PVL and brain abnormalities associated with PVL were also noted. Assignment to PVL grades on MRI was as follows: PVL I (n=22), PVL II (n=18), PVL III (n=30), and PVL IV (n=19). Cerebral palsy was slightly less common in children with PVL I and II compared with PVL III to IV. Motor function was normal in 50% of children with PVL grade I, but severely impaired in 73.7% of children with PVL grade IV. Results of visual function were normal in all with PVL I, but pathological in 42.1% of patients with PVL IV. Developmental tests were appropriate for age in 75% of patients with PVL I, but significantly delayed in all patients with PVL IV. Thinning of the corpus callosum and presence of cortical atrophy were also correlated with neurological outcome. Significant risk factors associated with developmental delay were asphyxia at birth (odds ratio [OR] 4.3), PVL localization numbers over 3 (OR 4.4), PVL III to IV (OR 15), thinning of corpus callosum, and cortical atrophy

A rare cause of brachial plexopathy: Hereditary neuralgic amyotrophy [Brakiyal pleksopatinin nadir bir nedeni: Herediter nevraljik amiyotrofi]

2-s2.0-85074084911Neuralgic amyotrophy is characterized by recurrent, painful, unilateral neuropathy involving mainly the upper brachial plexus followed by muscle weakness and muscle wasting. There are two forms: Idiopathic and hereditary. Hereditary neuralgic amyotrophy is an autosomal dominant disease that is often linked to a mutation of SEPT9, a gene of the Septin family. The phenotypic spectrum of the disease may include hypotelorism, cleft palate, and other minor dysmorphisms. The age of onset is from infancy to adulthood. Hereditary neuralgic amyotrophy can be triggered by external stimuli such as infections, vaccinations, cold, stress, surgery, and strenuous exercise. Here, we report a six-year-old girl who was found to have mutation in the SEPT9 gene when she presented with recurrent attacks of painful brachial plexopathy following vaccinations, and was diagnosed as having hereditary neuralgic amyotrophy. © Telif Hakkı 2019 Türk Pediatri Kurumu Dernegi Makale metnine