Effectiveness of some herbals on initial enamel caries lesion

Objective: To evaluate the effectiveness of herbal medicaments such as ginger, rosemary and honey on remineralization of initial enamel lesion. Methods: Demineralized human enamel specimens were measured for baseline surface microhardness and fluorescence methods. Ten specimens in each of four groups were used in this in vitro recycling study with the following treatments which applied three times a day: 1) sodium fluoride toothpaste (Ipana, Procter & Gamble, Turkey), 2) ginger-honey (Arifoglu Herbals, Anzer Honey, Turkey), 3) ginger-honey-chocolate (Bind Chocolate, Turkey), 4) rosemary oil (Arifoglu Herbals, Turkey). Treatment regimens of demineralization and remineralization cycle were applied for 21 days. The post-treatment data were obtained by measurements of surface microhardness and fluorescence methods. Data were statistically analyzed by ANOVA test with Tukey's honest significant difference test. Results: Enhanced remineralization was observed with several of the treatment systems including ginger + honey and rosemary. Significant differences between treatments were observed by microhardness and FluoreCam fluorescence assesment, compared to the positive control group (NaF dentifrice). Significantly, greater remineralization was observed with the honey + ginger treatment regimen. No significant differences between groups were observed using the fluorescence assessment method, quantitative light-induced fluorescence. Conclusions: Herbals (ginger, honey and rosemary) have enhanced remineralization of initial enamel lesion

Antibacterial susceptibility patterns of methicillin resistant staphylococcus spp. from a tertiary reference hospital

Objectives: Methicillin resistant Staphylococcus strainsstill remain as an important reason of hospital acquiredinfections. The aim of this study to see the antimicrobialsensitivity patterns of these strains for effective empiricaltherapyMaterial and methods: Antibiotic susceptibility resultsof staphylococcus strains were investigated retrospectivelyfrom tertiary reference hospital. 276 methicillin resistantstaphylococcus species, which were isolated fromKırıkkale University Faculty of Medicine Department of InfectiousDisease and Clinical Microbiology laboratory betweenNovember 2009-2010 were enrolled in this study.Identification and antibiotic susceptibilities of the strainswere evaluated by using Vitek automated systems (bioMerieux).Results: Most of these strains were isolated from blood(49%) and wound (40 %) samples. There was no glycopeptideresistance established from 276 strains. Susceptibilitypercents of these strains to linezolid and erythromycinwere 97% and 16% respectively.Conclusions: we believe that, informing physiciansabout antibiotic susceptibility patterns of methicillin resistantstaphylococcus species will be helpful for effectivetreatment and control the spread of these infections. JClin Exp Invest 2012; 3(1): 71-7

Farklı Bal Kabağı Anaç Adayları ile Aşılı Hıyar Çeşitlerinin Menderes Ovasında Verim ve Kalite Performanslarının Belirlenmesi

Amaç: Anaç ıslah programında geliştirilen bal kabağı anaç adaylarının örtüaltı hıyar yetiştiriciliğinde verim ve meyve kalite özellikleri bakımından performanslarının ticari anaçlarla ve aşısız bitkilerle karşılaştırarak, en uygun ümitvar anaç adaylarının belirlenmesidir. Materyal ve Metot: Araştırmada, tür içi 10 adet melez bal kabağı anaç adayı ve iki ticari kabak anacı (TZ148 ve RS841) ile Maya ve Sardes ticari çeşitleri kalem olarak kullanılmıştır. Tüm anaçlar, Sardes ve Maya çeşitleri ile aşılanmıştır. Ayrıca, aşısız Maya ve Sardes çeşitleri, kontrol bitkileri olarak değerlendirilmiştir. Meyve kalite ve verim unsurlarının belirlenmesine yönelik olarak; meyve boyu (cm), meyve çapı (cm), meyve şekil indeksi, meyve eti sertliği (kg/cm2 ), suda çözünebilir kuru madde (%), titre edilebilir asitlik (mval/100 ml), ortalama meyve ağırlığı (g), bitki başına meyve sayısı (adet), erkenci verim (kg/da) ve dekara verim (kg/da) değerleri incelenmiştir. Bulgular: Araştırma sonucunda; aynı anaç üzerine aşılanan farklı hıyar çeşitlerinde incelenen meyve kalite özelliklerinin önemli düzeyde farklılıklar gösterdiği belirlenmiştir. Ümitvar kabak anaçlarıyla aşılanan hıyar bitkilerinin, aşısız kontrol bitkilerine göre erkenci verim ve dekara verim değerleri yönünden daha iyi sonuçlar verdiği saptanmıştır. Sonuç: Bu çalışmadan elde edilen sonuçlar, aşılı hıyar bitkisi üretiminde geliştirilen RS9 ve RS13 hibrit bal kabağı anaç adaylarının, aşılı hıyar fidesi üretiminde ticari anaç potansiyellerinin oldukça yüksek olduğunu göstermiştir.Objective: The aim of this study was to compare the yield and fruit characteristics of the pumpkin rootstock candidates with commercial rootstocks and nongrafted plants in order to determine the most appropriate rootstock candidates. Material and Methods: In this research, 10 hybrid pumpkin rootstock candidates, two commercial rootstocks (TZ148 and RS841 cv.) were used as rootstocks. The rootstocks were grafted with Sardes and Maya commercial varieties and the nongrafted Sardes and Maya cultivars were used as the control. In order to determine the effect of rootstocks on cucumber fruit quality and yield components; fruit length (cm), fruit diameter (cm), fruit firmness (kg/cm2 ), soluble solids content (%), the titratable acidity (mval/100 ml), mean fruit weight (g), fruit number per plant, early and total yield (kg/da) parameters were examined. Results: It was determined that the properties examined in different cucumber varieties on the same rootstock differed significantly. In general, the cucumber plants grafted onto promising pumpkin rootstocks shown better results in terms of yield compared to nongrafted control plants. Conclusion: The results obtained from this study show that despite the preference of Cucurbita maxima x Cucurbita moschata hybrid rootstocks in grafted cucumber production, native RS9 and RS13 hybrid pumpkin candidates have economic potentials in the production of grafted cucumber seedlings

Effects of oleaster flour supplementation in total phenolic contents, antioxidant capacities and their bioaccessibilities of cookies

ALTINER, DILEK DULGER/0000-0002-7043-2883; Dundar, Ayse Neslihan/0000-0003-2084-7076WOS: 000492036200013PubMed: 31695938In presented study total phenolic contents, antioxidant capacities and their bioaccessibilities from cookies supplemented with oleaster flour were investigated. Oleaster flours (OFs) were produced using two different methods (peeled oleaster flour: POF and unpeeled oleaster flour: UPOF) from two different genotypes. OFs were used to replace wheat flour in the cookie formulation (control) at the levels of 5, 10, 15, 20 and 25% (w/w). According to the results, enrichment of OFs clearly increased total phenolic contents, antioxidant capacities and bioaccessibilities of cookies. The highest bioaccessible antioxidant capacities (ABTS, CUPRAC, and FRAP) of the samples were obtained from cookie samples enriched with 25% UPOF-1. In conclusion, the increases in phenolic contents, antioxidant capacities, and bioaccessibilities from cookies supplemented with OFs suggest the potential enhancement of beneficial health effect of cookie due to increased content of bioactive compounds present in oleaster flour.Scientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [TOVAG 110 O 060]The authors would like to thank The Scientific and Technological Research Council of Turkey (TUBITAK) for their financial support to this research project (Project No: TOVAG 110 O 060)

The cheapest way of the pain management after lumbar spinal surgical procedures: Cold pack application

İnsanlığın var olduğu dönemden günümüze, ağrı ve onun tedavisi tıbbın en önemli konusu olmuştur. Ağrı tedavisi için birçok yöntem uygulanmıştır. Spinal cerrahide tedavinin temel amacı da hastanın ağrısını geçirmek, günlük aktivitesine en kısa sürede dönmesini sağlamaktır. Ancak uygulanan tedaviden bağımsız olarak postoperatif şiddetli ağrı ortaya çıkar. Özellikle paravertebral kaslarda otomatik ekartörlerin uzun süreli kullanımı ve inflamatuar doku yanıtı bunda etkilidir. Bu sebeple postoperatif kuvvetli nonsteroid ve narkotik analjezikler kullanılmak zorunda kalınmaktadır. Uygulanan tedavilerin yan etkileri dışında mali açıdan da bir başka problemi yanında getirmektedir. Amaç: Yumuşak doku travmalarında ağrı ve ödemi azaltmak için buz tedavisi uygulaması bilinen çok eski bir yöntemdir. Bizde bu çalışmamızda hastaların uzamış paravertebral kas ekartasyonuna bağlı postoperatif ağrılarını soğuk kompresyon uygulaması ile azaltmayı, hasta memnuniyetini arttırmayı ve verilen ilaç dozlarını azaltmayı hedefledik. Metot: Kliniğimizde lomber spinal cerrahi yapılmış 60 hasta üzerinde randomize prospektif klinik çalışma yaptık. Cerrahi süresi, paravertebral kas ekartasyon süresi, nonsteroid veya narkotik analjezik kullanımı kaydedildi. Ağrı seviyeleri VAS skorlama yöntemi ile ölçüldü. Grup1 hastalara postoperatif 3 gün süreyle günde 4 defa 20 dakikalık seanslar halinde soğuk kompresyon uygulandı. Soğuk kompresyon uygulaması; piyasadan temin edilmiş olan 300g’ lık standart buz aküleriyle, hasta lateral dekübit pozisyonda iken cerrahi yara yeri pansumanı üzerinden bilateral paravertebral kasları kapatacak şekilde lokal uygulandı. Grup 2 (kontrol grubu) hastalar sadece medikal tedavi aldı. Postoperatif VAS24, VAS48, VAS72 değerleri körleme olarak kaydedildi. Sonuç: Çalışma ve Kontrol gruplarının VAS0 değerleri arasında istatistiksel olarak anlamlı bir fark yoktur (p>0,05).Gruplar arası VAS24-48-72 değerleri arasında istatistiksel olarak anlamlı bir fark vardır (p<0,05). Uzamış paravertebral kas ekartasyonuna bağlı gelişen postoperatif bel ağrılarının tedavisinde soğuk kompresyon uygulaması basit, ucuz, güvenli ve etkili bir yöntem olup hastaların postoperatif ağrılarını ve narkotik analjezik ihtiyaçlarını azaltmaktadır. Spinal cerrahinin farklı uygulamalarında bu metot denenebilir.The main purpose of surgical treatment of lumbar spine is to relieve the patient's pain, and to return the daily activity as soon as possible comfortably. In the postoperative period, severe pain due to long term use of paravertebral automatic retractors and inflammatory response occurs. We have to use nonsteroidal antiinflammatory drugs and narcotic analgesics for the pain. Besides the side effects of this treatment, another problem is encountered in financial viable. After soft tissue trauma to reduce pain and edema, ice applications is a well-known method. In our study, we aim to reduce the postoperative pain which depends on prolonged retraction of paravertebral muscles with the cold compression application, and to increase patient satisfaction and to reduce the dose of the drugs. We performed a prospective randomized study on 60 patients underwent the lumbar spinal surgery in our clinic. Duration of surgery and paravertebral muscle retraction, use of narcotic analgesics or nonsteroidal anti-inflammatory drugs were recorded. Pain levels were measured by VAS scoring. Patients in group 1 (study group) were applied cold compression postoperative 4 times a day for 3 days in case of 20-minute sessions. Cold compression application was performed with 300g standards ice packs which are commercially available. Ice packs were applied locally through the surgical wound dressing covering bilateral paravertebral muscles while the patient is in lateral decubitus position. Patients in group 2 (control group) received only medical treatment. Postoperative VAS 24, 48, 72 time values were recorded. There is no statistically significant difference between the VAS 0 value of the control and study groups (p > 0,05). There is a statistically significant difference between the VAS 24, 48, 7 2 values of the control and study groups (p < 0.05). Cold compression therapy in the treatment of postope r ative back pain due to prolonged paravertebral muscle retraction is simple, inexpensive, safe and effective method of postoperative pain and narcotic analgesic needs of patients decreases.This method can be tried in different areas of spinal surgery. © Gülhane Askeri Tip Akademisi 2016

Investigation of Biofilm Formation of ESBL Positive Uropathogenic Escherichia coli Isolates on (Microplate) Surfaces Modified with Plasma Polymerization Technique and Nanomaterials: An Experimental Model

Objective: Extended spectrum beta lactamase (ESBL) positive urinary pathogen Escherichia coli is one of the major agents that lead to catheter-associated urinary tract infection. Prevention of colonization via coating the catheter with biocompatible materials produced by biotechnology is an important step in the prevention of infection. In the presented study, it was aimed to investigate the biofilm formation of ESBL positive urinary pathogen E. coli isolates on microplates which were coated with different bio-compatible nano-materials. Materials and Methods: Biofilm formation of a total of 45 ESBL positive E. coli isolates identified at urine cultures of patients who attended to the medical and surgical outpatient clinics of Ankara TOBB ETU Hospital, on microplates coated with two different monomers [2- hydroxyethyl methacrylate (HEMA) and ethylene glycol dimethacrylate (EGDM)] using plasma polymerization technique was examined. Results: Out of 45 ESBL positive E. coli strains used in the study, 8 were observed to form a slight level of biofilm on uncoated plates whereas on EGDM coated microplates 11, and on HEMA coated microplate only 1 strain formed biofilm. Conclusion: In vitro results showed that using urinary catheters coated with monomer material can reduce catheter associated urinary system infections and morbidity and mortality rates accordingly.Amaç: Kateter ilişkili üriner sistem enfeksiyonlarına neden olan önemli etkenlerden biri GSBL pozitif üropatojen Escherichia coli’dir. Biyoteknoloji ile üretilen biyouyumlu malzemenin katatere kaplanarak kolonizasyonun engellenmesi enfeksiyonun önlenmesinde önemli bir aşamadır. Sunulan araştırmada, GSBL pozitif üropatojen E. coli izolatlarının farklı biyouyumlu nanomalzemelerle kaplanmış mikroplaklardaki biyofilm oluşumuna etkisinin incelemesi amaçlanmıştır. Gereç ve Yöntem: Ankara TOBB ETÜ Hastanesi dâhili ve cerrahi polikliniklere başvuran ayaktan hastaların idrar kültüründen izole toplam 45 GSBL pozitif E. coli izolatının plazma polimerizasyon yöntemiyle iki farklı monomerle [2–hidroksietilmetakrilat (HEMA)] ve Etilen glikol dimetakrilat (EGDM)] kaplanmış mikroplaklarda biyofilm oluşumu araştırılmıştır. Bulgular: Araştırmada kullanılan 45 GSBL pozitif E. coli suşunun 8 tanesi standart yöntemler ile boş plaklarda hafif düzeyde biyofilm oluştururken, EGDM ile kaplanmış mikroplakta 11, HEMA ile kaplanmış mikroplakta ise yalnızca 1 suş biyofilm tabaka oluşturmuştur. Sonuç: Monomer yapılarla kaplanmış üriner kateterlerin kullanılmasının üriner sistemde kateter ilişkili enfeksiyonlarını ve buna bağlı morbidite ve mortalite oranlarını azaltabileceğini gösteren in vitro sonuçlar elde edilmiştir

Assessment of micro-hardness, degree of conversion, and flexural strength for single-shade universal resin composites

© 2022 by the authors.Single-shade universal resin composites (SsURC) are preferred in clinical practice to reduce time for shade selection and obtain good esthetic results. In this study, the static mechanical properties of seven new SsURCs were investigated, their spectral analyzes were performed and scanning electron microscopy (SEM) evaluations were presented. Charisma Diamond One/DO, Admira Fusion x-tra/AFX, Omnichroma/OC, OptiShade/OS, Essentia Universal/EU, Zenchroma/ZC, Vittra APS Unique/VU were used in a three-point bending test to determine flexural strength (FS) and elastic modulus (EM); Vickers micro-hardness (VHN) and hardness-ratio (HR) were performed with a micro-hardness tester from top/bottom after 24-h/15-days of storage in distilled water at 37 °C (±1 °C). The degree of conversion (DC) was assessed by using Fourier transform infrared spectroscopy (FTIR). The structure of the resin matrix and filler content were assessed by SEM. Data were analyzed using IBM SPSS V23 and the R program and the significance level was taken as p < 0.05. The main effect of the tested SsURCs was found to be statistically significant on FS, EM, VHN, and DC values (p < 0.001). Bis-GMA free SsURCs (AFX, DO, VU) showed better DC and HR except for OC. All seven tested SsURCs conform to the requirements of ISO standards for dental resin composites for all tested categories