Numerical Simulation for Droplet Combustion Using Lagrangian Hydrodynamics

A predictive model of spray combustion must incorporate models for the wide variety of physical environments in a practical combustor. In regions where droplets are closely spaced, combustion resembles a diffusion flame; where they are well separated, an envelope or wake flame results. The relative velocity field between the fuel droplets and oxidizer in influences boundary layer development about the droplet, recirculating flow patterns, and droplet shape and stability. A model must encompass these interacting temporal and spatial effects as well as complicated combustor boundaries. The objective of the current work is to develop the triangular gridding method for describing the individual and collective properties of vaporizing and burning fuel droplets

Numerical simulations of fuel droplet flows using a Lagrangian triangular mesh

The incompressible, Lagrangian, triangular grid code, SPLISH, was converted for the study of flows in and around fuel droplets. This involved developing, testing and incorporating algorithms for surface tension and viscosity. The major features of the Lagrangian method and the algorithms are described. Benchmarks of the algorithms are given. Several calculations are presented for kerosene droplets in air. Finally, extensions which make the code compressible and three dimensional are discussed

The challenges of change:Exploring the dynamics of police reform in Scotland

Despite a long tradition of pessimism regarding the scope for meaningful change in police practices, recent structural reforms to police organizations in several European countries suggest that significant change in policing is possible. Drawing on recent research into the establishment and consequences of a national police force in Scotland, this article uses instrumental, cultural and myth perspectives taken from organization theory to examine how change happened and with what effects. It highlights how police reform involves a complex interplay between the strategic aims of government, the cultural norms of police organizations and the importance of alignment with wider views about the nature of the public sector. The article concludes by identifying a set of wider lessons from the experience of organizational change in policing

Lack of association between the rs2294008 polymorphism in the prostate stem cell antigen gene and colorectal neoplasia : a case-control and immunohistochemical study

PMID: 22824379 [PubMed - indexed for MEDLINE] PMCID: PMC3500224 Free PMC ArticlePeer reviewedPublisher PD

Combination of gastric atrophy, reflux symptoms and histological subtype indicates two distinct aetiologies of gatric cardia cancer.

<b>INTRODUCTION</b> Atrophic gastritis is a risk factor for non-cardia gastric cancer, and gastro-oesophageal reflux disease (GORD) for oesophageal adenocarcinoma. The role of atrophic gastritis and GORD in the aetiology of adenocarcinoma of the cardia remains unclear. We have investigated the association between adenocarcinoma of the different regions of the upper gastrointestinal tract and atrophic gastritis and GORD symptoms. <b>METHODS</b> 138 patients with upper GI adenocarcinoma and age and sex matched controls were studied. Serum pepsinogen I/II was used as a marker of atrophic gastritis and categorised to five quintiles. History of GORD symptoms, smoking and H.pylori infection was incorporated in logistic regression analysis. Lauren classification of gastric cancer was used to subtype gastric and oesophageal adenocarcinoma. <b>RESULTS</b> Non-cardia cancer was associated with atrophic gastritis but not with GORD symptoms; 55% of these cancers were intestinal subtype. Oesophageal adenocarcinoma was associated with GORD symptoms, but not with atrophic gastritis; 84% were intestinal subtype. Cardia cancer was positively associated with both severe gastric atrophy [OR, 95% CI: 3.92 (1.77 – 8.67)] and with frequent GORD symptoms [OR, 95% CI: 10.08 (2.29 – 44.36)] though the latter was only apparent in the nonatrophic subgroup and in the intestinal subtype. The association of cardia cancer with atrophy was stronger for the diffuse versus intestinal subtype and this was the converse of the association observed with non-cardia cancer. <b>CONCLUSION</b> These findings indicate two distinct aetiologies of cardia cancer, one arising from severe atrophic gastritis and being of intestinal or diffuse subtype similar to non-cardia cancer, and one related to GORD and intestinal in subtype, similar to oesophageal adenocarcinoma. Gastric atrophy, GORD symptoms and histological subtype may distinguish between gastric versus oesophageal origin of cardia cancer

Effect of High-Protein Breakfast Meals on Within-Day Appetite and Food Intake in Healthy Men and Women

The Rowett Institute and Biomathematics and Statistics Scotland are grateful to the Scottish Government for funding this work. We thank the Rowett Human Nutrition Unit staff for their technical help with the interventions. Staff members who helped include Jean Bryce, Nina Lamza and Karen Taylor. The Rowett Institute and Biomathematics and Statistics Scotland are grateful to the Scottish Government for funding this work.Peer reviewedPublisher PD

Rapid and sensitive detection of mycobacterium ulcerans by use of a loop-mediated isothermal amplification test

This work reports the design and evaluation of a rapid loop-mediated isothermal amplification test for detecting Mycobacterium ulcerans DNA based on the multicopy insertion sequence IS2404. The test is robust and specific with a detection limit equivalent to 20 copies of the target sequence (0.01 to 0.1 genome). The test has potential for the diagnosis of Buruli ulcer under field conditions