The lady's not for burning.

Thesis (M.A.)--Boston Universit

The Lady\u27s Not for Burning (March 7, 1952)

Program for The Lady\u27s Not for Burning (March 7, 1952). To view the photos from this production of The Lady\u27s Not for Burning, please click here

The Boy with a Cart (May 12, 16, 1965)

Program for The Boy with a Cart (May 12, 16, 1965)

Cosmological structure formation from soft topological defects

Some models have extremely low-mass pseudo-Goldstone bosons that can lead to vacuum phase transitions at late times, after the decoupling of the microwave background.. This can generate structure formation at redshifts z greater than or approx 10 on mass scales as large as M approx 10 to the 18th solar masses. Such low energy transitions can lead to large but phenomenologically acceptable density inhomogeneities in soft topological defects (e.g., domain walls) with minimal variations in the microwave anisotropy, as small as delta Y/T less than or approx 10 to the minus 6 power. This mechanism is independent of the existence of hot, cold, or baryonic dark matter. It is a novel alternative to both cosmic string and to inflationary quantum fluctuations as the origin of structure in the Universe

Antigen-Experienced CD4lo T Cells Are Linked to Deficient Contraction of the Immune Response in Autoimmune Diabetes

Following proper activation, naïve “CD4lo” T cells differentiate into effector T cells with enhanced expression of CD4 -“CD4hi” effectors. Autoimmune diabetes-prone NOD mice display a unique set of antigen-experienced “CD4lo” T cells that persist after primary stimulation. Here, we report that a population of such cells remained after secondary and tertiary TCR stimulation and produced cytokines upon antigenic challenge. However, when NOD blasts were induced in the presence of rIL-15, the number of antigen-experienced “CD4lo” T cells was significantly reduced. Clonal contraction, mediated in part by CD95-dependent activation-induced cell death (AICD), normally regulates the accumulation of “CD4hi” effectors. Interestingly, CD95 expression was dramatically reduced on the AICD-resistant NOD “CD4lo” T cells. Thus, while autoimmune disease has often been attributed to the engagement of robust autoimmunity, we suggest that the inability to effectively contract the immune response distinguishes benign autoimmunity from progressive autoimmune diseases that are characterized by chronic T cell-mediated inflammation

SXSAQCT and XSAQCT: XML Queryable Compressors

Recently, there has been a growing interest in queryable XML compressors, which can be used to query compressed data with minimal decompression, or even without any decompression. At the same time, there are very few such projects, which have been made available for testing and comparisons. In this paper, we report our current work on two novel queryable XML compressors; a schema-based compressor, SXSAQCT, and a schema-free compressor, XSAQCT. While the work on both compressors is in its early stage, our experiments (reported here) show that our approach may be successfully competing with other known queryable compressors

Script-Based Story Matching for Cyberbullying Prevention

While the Internet and social media help keep today’s youth better connected to their friends, family, and community, the same media are also the form of expression for an array of harmful social behaviors, such as cyberbullying and cyber-harassment. In this paper we present work in progress to develop intelligent interfaces to social media that use commonsense knowledge bases and automated narrative analyses of text communications between users to trigger selective interventions and prevent negative outcomes. While other approaches seek merely to classify the overall topic of the text, we try to match stories to finer-grained “scripts” that represent stereotypical events and actions. For example, many bullying stories can be matched to a “revenge” script that describes trying to harm someone who has harmed you. These tools have been implemented in an initial prototype system and tested on a database of real stories of cyberbullying collected on MTV’s “A Thin Line” Web site

Performance Motion Analysis Unable to Predict Running-Related Injury in Collegiate Distance Runners

ABSTRACT Purpose: Running-related injury (RRI) is common among competitive collegiate distance runners who participate in the sport of cross country and long distance track and field. Many factors contribute to RRI. Therefore, the purpose of this study was to determine if a 3D motion capture system’s performance motion analysis (PMA) report is capable of identifying factors predictive of RRI among collegiate distance runners during a cross country season. Methods: Thirty-one collegiate cross country runners (17 male, 14 female, mean age = 20.5 ± 1.4 years) gave their consent to participate in the investigation. Subjects were screened in the motion capture system and provided with PMA reports assessing their movement quality using several variables (composite score, power, strength, dysfunction, and vulnerability, based on measurements of 192 kinetic and kinematic variables). The athletes were then monitored throughout their 13-week competitive season for incidence of RRI. At the end of the season, participants were sorted into injured (n=17) and uninjured (n=14) groups. Injury was defined as appearing on the team injury report as missing or being limited in practice or competition for a week or more, in accordance with prior RRI research. Each sex was also separated into groups based on injury status. Results: Independent samples t-tests (pConclusion: The findings identified in this prospective study suggest that the movement screen was unable to identify runners at risk of injury. Future investigations isolating lower extremity movement characteristics in runners may prove more effective at predicting RRI

Ascorbate degradation: pathways, products and possibilities

A role for l-ascorbate as the precursor of several plant compounds adds to its already broad metabolic utility. There are many examples of plant species in which oxalate and l-threonate are formed from l-ascorbate breakdown, and a number of roles have been proposed for this: structural, physiological, and biochemical. On the other hand, the synthesis of l-tartrate from l-ascorbate remains limited to a very few species, amongst which we must be grateful to count the domesticated grapevine Vitis vinifera and its relatives on which wine production is based. Pathways for the degradation of ascorbate were first proposed ~50 years ago and have formed the basis of more recent biochemical and molecular analyses. The present review seeks to summarize some of these findings and to propose opportunities for future research.</p