The Permeable Classroom or the Tilted Arc Revisited

The Permeable Classroom or the Tilted Arc Revisited reviews the author\u27s various roles as artist, community activist, art educator and art therapist, in the design and implementation of a large, sequential community-based \u27\u27Tree Memorial project. Using the Tree Memorial Project as a compelling example of the permeable classroom, the paper delivers an overview of the project that takes place in and around the public school setting, featuring collaboration between teachers, students, parents, administrators, community residents, and city officials

Supermodular comparison of dependence models and multivariate processes, with applications

The supermodular order is a well-known tool to compare the intrinsic degree of dependence between random vectors or multivariate processes. In this note we describe a general framework for the supermodular comparisons of models incorporating individual and common factors. Examples are given on how to apply these models in comparing hitting times for multivariate processes of interest within risk analysis and reliability theory

A reinsurance risk model with a threshold coverage policy : the Gerber-Shiu penalty function

We consider a Cramér-Lundberg insurance risk process with the added feature of reinsurance. If an arriving claim finds the reserve below a certain threshold ¿, or if it would bring the reserve below that level, then a reinsurer pays part of the claim. Using fluctuation theory and the theory of scale functions of spectrally negative Lévy processes, we derive expressions for the Laplace transform of the time to ruin and of the joint distribution of the deficit at ruin and the surplus before ruin. We specify these results in much more detail for the threshold set-up with proportional reinsurance

Hemodynamic Responses Evoked by Neuronal Stimulation via Channelrhodopsin-2 Can Be Independent of Intracortical Glutamatergic Synaptic Transmission

Maintenance of neuronal function depends on the delivery of oxygen and glucose through changes in blood flow that are linked to the level of ongoing neuronal and glial activity, yet the underlying mechanisms remain unclear. Using transgenic mice expressing the light-activated cation channel channelrhodopsin-2 in deep layer pyramidal neurons, we report that changes in intrinsic optical signals and blood flow can be evoked by activation of a subset of channelrhodopsin-2-expressing neurons in the sensorimotor cortex. We have combined imaging and pharmacology to examine the importance of glutamatergic synaptic transmission in this form of neurovascular coupling. Blockade of ionotropic glutamate receptors with the antagonists CNQX and MK801 significantly reduced forepaw-evoked hemodynamic responses, yet resulted in no significant reduction of channelrhodopsin-evoked hemodynamic responses, suggesting that stimulus-dependent coupling of neuronal activity to blood flow can be independent of local excitatory synaptic transmission. Together, these results indicate that channelrhodopsin-2 activation of sensorimotor excitatory neurons produces changes in intrinsic optical signals and blood flow that can occur under conditions where synaptic activation of neurons or other cells through ionotropic glutamate receptors would be blocked

A Functional Architecture of Optic Flow in the Inferior Parietal Lobule of the Behaving Monkey

The representation of navigational optic flow across the inferior parietal lobule was assessed using optical imaging of intrinsic signals in behaving monkeys. The exposed cortex, corresponding to the dorsal-most portion of areas 7a and dorsal prelunate (DP), was imaged in two hemispheres of two rhesus monkeys. The monkeys actively attended to changes in motion stimuli while fixating. Radial expansion and contraction, and rotation clockwise and counter-clockwise optic flow stimuli were presented concentric to the fixation point at two angles of gaze to assess the interrelationship between the eye position and optic flow signal. The cortical response depended upon the type of flow and was modulated by eye position. The optic flow selectivity was embedded in a patchy architecture within the gain field architecture. All four optic flow stimuli tested were represented in areas 7a and DP. The location of the patches varied across days. However the spatial periodicity of the patches remained constant across days at ∼950 and 1100 µm for the two animals examined. These optical recordings agree with previous electrophysiological studies of area 7a, and provide new evidence for flow selectivity in DP and a fine scale description of its cortical topography. That the functional architectures for optic flow can change over time was unexpected. These and earlier results also from inferior parietal lobule support the inclusion of both static and dynamic functional architectures that define association cortical areas and ultimately support complex cognitive function