472 research outputs found

    STAR: Sparse Trained Articulated Human Body Regressor

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    The SMPL body model is widely used for the estimation, synthesis, and analysis of 3D human pose and shape. While popular, we show that SMPL has several limitations and introduce STAR, which is quantitatively and qualitatively superior to SMPL. First, SMPL has a huge number of parameters resulting from its use of global blend shapes. These dense pose-corrective offsets relate every vertex on the mesh to all the joints in the kinematic tree, capturing spurious long-range correlations. To address this, we define per-joint pose correctives and learn the subset of mesh vertices that are influenced by each joint movement. This sparse formulation results in more realistic deformations and significantly reduces the number of model parameters to 20% of SMPL. When trained on the same data as SMPL, STAR generalizes better despite having many fewer parameters. Second, SMPL factors pose-dependent deformations from body shape while, in reality, people with different shapes deform differently. Consequently, we learn shape-dependent pose-corrective blend shapes that depend on both body pose and BMI. Third, we show that the shape space of SMPL is not rich enough to capture the variation in the human population. We address this by training STAR with an additional 10,000 scans of male and female subjects, and show that this results in better model generalization. STAR is compact, generalizes better to new bodies and is a drop-in replacement for SMPL. STAR is publicly available for research purposes at http://star.is.tue.mpg.de.Comment: ECCV 202

    Spotting the diffusion of New Psychoactive Substances over the Internet

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    Online availability and diffusion of New Psychoactive Substances (NPS) represent an emerging threat to healthcare systems. In this work, we analyse drugs forums, online shops, and Twitter. By mining the data from these sources, it is possible to understand the dynamics of drugs diffusion and their endorsement, as well as timely detecting new substances. We propose a set of visual analytics tools to support analysts in tackling NPS spreading and provide a better insight about drugs market and analysis

    Costs associated with febrile neutropenia in solid tumor and lymphoma patients - an observational study in Singapore.

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    BackgroundThe primary objective was to describe the total direct inpatient costs among solid tumor and lymphoma patients with chemotherapy-induced febrile neutropenia (FN) and the factors that were associated with higher direct cost. The secondary objective was to describe the out-of-pocket patient payments and the factors that were associated with higher out-of-pocket patient payments.MethodsThis was a single-center observational study conducted at the largest cancer center in Singapore. All of the adult cancer patients hospitalized due to FN from 2009 to 2012 were studied. The primary outcomes were the total hospital cost and the out-of-pocket patient payments (adjusted by government subsidy) per FN episode. Univariate analysis and multiple linear regression were conducted to identify the factors associated with higher FN costs.ResultsThree hundred and sixty seven adult cancer patients were documented with FN-related hospitalizations. The mean total hospital cost was US4,193(954,193 (95% CI: US3,779-4,607) and the mean out-of-pocket patient payment was US2,230(952,230 (95% CI: US1,976-2,484), per FN episode. The factors associated with a higher total hospital cost were longer length of stay, severe sepsis, and lymphoma as underlying cancer. The out-of-pocket patient payment was positively associated with longer length of stay, severe sepsis, lymphoma diagnosed as underlying cancer, the therapeutic use of granulocyte colony-stimulating factor (GCSF), the private ward class, and younger patients.ConclusionsThe total hospital cost and out-of-pocket patient payments of FN management in lymphoma cases were substantial compared with other solid tumors. Factors associated with a higher FN management cost may be useful for developing appropriate strategies to reduce the cost of FN for cancer patients

    Characteristics of US public schools with reported cases of novel influenza A (H1N1)

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    Objective The 2009 pandemic of influenza A (H1N1) has disproportionately affected children and young adults, resulting in attention by public health officials and the news media on schools as important settings for disease transmission and spread. We aimed to characterize US schools affected by novel influenza A (H1N1) relative to other schools in the same communities. Methods A database of US school-related cases was obtained by electronic news media monitoring for early reports of novel H1N1 influenza between April 23 and June 8, 2009. We performed a matched case–control study of 32 public primary and secondary schools that had one or more confirmed cases of H1N1 influenza and 6815 control schools located in the same 23 counties as case schools. Results Compared with controls from the same county, schools with reports of confirmed cases of H1N1 influenza were less likely to have a high proportion of economically disadvantaged students (adjusted odds ratio (aOR) 0.385; 95% confidence interval (CI) 0.166–0.894) and less likely to have older students (aOR 0.792; 95% CI 0.670–0.938). Conclusions We conclude that public schools with younger, more affluent students may be considered sentinels of the epidemic and may have played a role in its initial spread.National Institute of Allergy and Infectious Diseases (U.S.) (R21AI073591-01)National Institutes of Health (U.S.)Canadian Institutes of Health Research (PAN-83152)Canadian Institutes of Health Research (CAT-86857)Google (Firm) (Research Grant

    Investigation of risk factors for introduction of highly pathogenic avian influenza H5N1 infection among commercial turkey operations in the United States, 2022: a case-control study

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    Introduction: The 2022–2023 highly pathogenic avian influenza (HPAI) H5N1 outbreak in the United States (U.S.) is the largest and most costly animal health event in U.S. history. Approximately 70% of commercial farms affected during this outbreak have been turkey farms. Methods: We conducted a case-control study to identify potential risk factors for introduction of HPAI virus onto commercial meat turkey operations. Data were collected from 66 case farms and 59 control farms in 12 states. Univariate and multivariable analyses were conducted to compare management and biosecurity factors on case and control farms. Results: Factors associated with increased risk of infection included being in an existing control zone, having both brooders and growers, having toms, seeing wild waterfowl or shorebirds in the closest field, and using rendering for dead bird disposal. Protective factors included having a restroom facility, including portable, available to crews that visit the farm and workers having access and using a shower at least some of the time when entering a specified barn. Discussion: Study results provide a better understanding of risk factors for HPAI infection and can be used to inform prevention and control measures for HPAI on U.S. turkey farms
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