Estudio de inundación en el tramo del centro poblado Manchuria al centro poblado Sandial en el distrito de Pítipo, provincia de Ferreñafe, departamento de Lambayeque, mediante el uso de los software HEC-HMS E IBER

La presente tesis busca desarrollar un mapa de inundación en uno de los departamentos con más daños por inundaciones como es Lambayeque, específicamente este estudio se centra en el tramo del río La Leche comprendido desde el centro poblado Manchuria al centro poblado Sandial distrito de Pítipo, en la provincia de Ferreñafe. La creación del mapa de inundación tendrá en cuenta la caracterización de la cuenca, el análisis hidrológico e hidráulico, siendo el primero el que brinda datos geomorfológicos de la cuenca en estudio seguido del análisis hidrológico, en el cual se hallaron los caudales para tiempos de retorno de 100, 200 y 500 años para conseguir el caudal máximo utilizando el software Hec-Hms. Finalmente, el análisis hidráulico abarcó desde la generación de la topografía mediante el DEM proporcionado por la NASA para realizar la simulación hidráulica mediante el software IBER obteniendo los tirantes máximos del río para cada periodo de retorno mencionado. Una vez obtenido todos los tirantes máximos, se utilizará el programa ArcGis en el cual se plasmará el mapa de inundación para obtener las zonas críticas de inundación y poder proponer alternativas de solución al problema que se generaría por el desborde del río La Leche en el tramo en estudio

Estudio e implementación preliminar de un prototipo para el monitoreo de humedad en el proceso de secado de arroz

El proyecto consiste en simular el proceso de secado de arroz con aire caliente en albercas y realizar su respectivo monitoreo de contenido de humedad en dichas albercas, mediante un sistema constituido por un elemento primario y un circuito medidor de humedad, permitiendo realizar un análisis del comportamiento de esta variable en el transcurso del proceso. Éste a su vez, involucra la aplicación de circuitos capaces de proporcionar valores de corriente, de acuerdo a variaciones en la resistividad del grano, originados por la extracción de humedad del arroz. Igualmente se busca una distribución del flujo de calor que permita simular el proceso bajo las condiciones típicas del secado. Como primera medida, se estudia el proceso de secado de arroz, los factores que influyen en éste, los equipos empleados para su funcionamiento, las variables humedad y temperatura en el grano y el comportamiento de dichas variables durante el proceso. A partir de estos conceptos, se analizan los métodos de medición capacitivo y resistivo, sus características, principio de funcionamiento, ventajas y desventajas del mismo. Así mismo, se hace referencia a otros métodos de medición de humedad menos difundidos en Colombia y a métodos aplicados en algunos instrumentos de medición utilizados comercialmente.Incluye bibliografí

The ecology and evolution of the monito del monte, a relict species from the southern South America temperate forests

The arboreal marsupial monito del monte (genus Dromiciops, with two recognized species) is a paradigmatic mammal. It is the sole living representative of the order Microbiotheria, the ancestor lineage of Australian marsupials. Also, this marsupial is the unique frugivorous mammal in the temperate rainforest, being the main seed disperser of several endemic plants of this ecosystem, thus acting as keystone species. Dromiciops is also one of the few hibernating mammals in South America, spending half of the year in a physiological dormancy where metabolism is reduced to 10% of normal levels. This capacity to reduce energy expenditure in winter contrasts with the enormous energy turnover rate they experience in spring and summer. The unique life history strategies of this living Microbiotheria, characterized by an alternation of life in the slow and fast lanes, putatively represent ancestral traits that permitted these cold-adapted mammals to survive in this environment. Here, we describe the ecological role of this emblematic marsupial, summarizing the ecophysiology of hibernation and sociality, updated phylogeographic relationships, reproductive cycle, trophic relationships, mutualisms, conservation, and threats. This marsupial shows high densities, despite presenting slow reproductive rates, a paradox explained by the unique characteristics of its three-dimensional habitat. We finally suggest immediate actions to protect these species that may be threatened in the near future due to habitat destruction and climate change.Fil: Fontúrbel, Francisco E.. Pontificia Universidad Católica de Valparaíso; ChileFil: Franco, Lida M.. Universidad de Ibagué; ColombiaFil: Bozinovic, Francisco. Pontificia Universidad Católica de Chile; ChileFil: Quintero Galvis, Julian F.. Universidad Austral de Chile; ChileFil: Mejías, Carlos. Universidad Austral de Chile; ChileFil: Amico, Guillermo Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto de Investigaciones en Biodiversidad y Medioambiente. Universidad Nacional del Comahue. Centro Regional Universidad Bariloche. Instituto de Investigaciones en Biodiversidad y Medioambiente; ArgentinaFil: Vazquez, Miriam Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto de Investigaciones en Biodiversidad y Medioambiente. Universidad Nacional del Comahue. Centro Regional Universidad Bariloche. Instituto de Investigaciones en Biodiversidad y Medioambiente; ArgentinaFil: Sabat, Pablo. Universidad de Chile; ChileFil: Sánchez Hernández, Juan C.. Universidad de Castilla-La Mancha; EspañaFil: Watson, David M.. Charles Sturt University; AustraliaFil: Saenz Agudelo, Pablo. Universidad Austral de Chile; ChileFil: Nespolo, Roberto F.. Universidad Austral de Chile; Chil

Investigating mechanisms of collective action initiatives’ development in the energy sector. Report on the comparative case studies, COMETS H2020 project

One of the emergent trends in the sustainable energy transition is the development of distributed power generation. In Europe, it is estimated that up half of citizens of the European Union (EU) could be energy self-sufficient, potentially supplying 45% of Europe’s final energy demand by 2050 (Kampman, et al., 2016). While there are many challenges with a move towards more distributed, citizen-led energy projects, they are nevertheless supported and promoted by the EU in the RED II (EU Renewable Energy Directive as part of the 2016 “Clean Energy of all Europeans” initiative, directive 2018/2001/EU), which secures the right for citizens and communities to produce, store, consume and sell renewable energy, and other rights such as consumer’s protection or access to all energy markets directly or through third parties. Socially, this often takes the form of community energy projects in the form of collective action initiatives (CAI). CAIs, which include energy cooperatives, prosumer networks, and other citizen-led energy projects, are examples of social innovation (Gregg, et al., 2020) in how they organize and gain power through a social movement mechanism. Social innovation is the development of activities and services to meet a social need, and social innovations are primarily social in both their ends and their means. Among other things, energy CAIs are typically characterized by a focus on the community, open and voluntary participation, democratic governance, and autonomy and independence (ICA, 2021). The social benefits of energy CAIs include: developing local economies, addressing energy poverty, raising awareness about sustainable energy, promoting energy justice, giving a voice to the community, developing local skills and promoting social cohesion. Current research on CAIs explores how they are defined and the different ownership structures (Gorroño-Albizu, 2019), and how they mobilize and attain power (Gregg et al., 2020). Other research traces the history of their development within specific contexts or geographical areas, and how they influence or are influenced by national energy policies (Wierling et al., 2018). Still other research uses the lens of organizational and institutional theory to understand the historical development of energy CAIs (Mey and Diesendorf, 2018)

The clinical use of circulating tumor cells (CTCs) enumeration for staging of metastatic breast cancer (MBC): International expert consensus paper

BACKGROUND: The heterogeneity of metastatic breast cancer (MBC) necessitates novel biomarkers allowing stratification of patients for treatment selection and drug development. We propose to use the prognostic utility of circulating tumor cells (CTCs) for stratification of patients with stage IV disease. METHODS: In a retrospective, pooled analysis of individual patient data from 18 cohorts, including 2436 MBC patients, a CTC threshold of 5 cells per 7.5\u2009ml was used for stratification based on molecular subtypes, disease location, and prior treatments. Patients with 65 5 CTCs were classified as Stage IVaggressive, those with < 5 CTCs as Stage IVindolent. Survival was analyzed using Kaplan-Meier curves and the log rank test. RESULTS: For all patients, Stage IVindolent patients had longer median overall survival than those with Stage IVaggressive (36.3 months vs. 16.0 months, P\u2009<\u20090.0001) and similarly for de novo MBC patients (41.4 months Stage IVindolent vs. 18.7 months Stage IVaggressive, p\u2009<\u20090.0001). Moreover, patients with Stage IVindolent disease had significantly longer overall survival across all disease subtypes compared to the aggressive cohort: hormone receptor-positive (44 months vs. 17.3 months, P\u2009<\u20090.0001), HER2-positive (36.7 months vs. 20.4 months, P\u2009<\u20090.0001), and triple negative (23.8 months vs. 9.0 months, P\u2009<\u20090.0001). Similar results were obtained regardless of prior treatment or disease location. CONCLUSIONS: We confirm the identification of two subgroups of MBC, Stage IVindolent and Stage IVaggressive, independent of clinical and molecular variables. Thus, CTC count should be considered an important tool for staging of advanced disease and for disease stratification in prospective clinical trials

Zero by 2030 and OneHealth: The multidisciplinary challenges of rabies control and elimination

"Rabies, caused by a negative strand RNA-virus belonging to the genus Lyssavirus (family Rhabdoviridae of the order Mononegavirales), remains of global concern [1]. This vaccine-preventable viral zoonotic disease is present in more than 150 countries and territories [2]. Ac- cording to the World Health Organization (WHO), rabies is estimated to cause ~59,000 human deaths annually, with 95% of cases occurring in Africa and Asia [3,4]. However, rabies still occurs in other regions, such as Latin America and the Caribbean [5–8], Central Asia and the Middle East [9,10]. Whilst a number of animals can host the rabies virus, dogs are the main source of human rabies deaths, contributing up to 99% of all rabies transmissions to humans. Dog-mediated rabies has been eliminated from Western Europe, Canada, the United States of America (USA), Japan and some Latin American countries [11]. Nevertheless, the risk of reintroduction and disease among travellers to risk areas is a matter of concern [12–15]. As occurred with many other communicable and non-communicable diseases, the 2020–2022 COVID-19 pandemic negatively impacted the efforts of control and reemergence of rabies in certain countries [7,16,17]. Post-pandemic challenges to enhance con- trol and prevention are multiple and need urgent actions to achieve the goal in eight years by 2030 [16].