La gestión pública de la vivienda y su impacto en la calidad de la infraestructura los desarrollos de vivienda Sector Noreste de la ciudad de Ensenada B.C.

Peer Reviewe

Smart systems related to polypeptide sequences

Increasing interest for the application of polypeptide-based smart systems in the biomedical field has developed due to the advantages given by the peptidic sequence. This is due to characteristics of these systems, which include: biocompatibility, potential control of degradation, capability to provide a rich repertoire of biologically specific interactions, feasibility to self-assemble, possibility to combine different functionalities, and capability to give an environmentally responsive behavior. Recently, applications concerning the development of these systems are receiving greater attention since a targeted and programmable release of drugs (e.g. anti-cancer agents) can be achieved. Block copolymers are discussed due to their capability to render differently assembled architectures. Hybrid systems based on silica nanoparticles are also discussed. In both cases, the selected systems must be able to undergo fast changes in properties like solubility, shape, and dissociation or swelling capabilities. This review is structured in different chapters which explain the most recent advances on smart systems depending on the stimuli to which they are sensitive. Amphiphilic block copolymers based on polyanionic or polycationic peptides are, for example, typically employed for obtaining pH-responsive systems. Elastin-like polypeptides are usually used as thermoresponsive polymers, but performance can be increased by using techniques which utilize layer-by-layer electrostatic self-assembly. This approach offers a great potential to create multilayered systems, including nanocapsules, with different functionality. Recent strategies developed to get redox-, magnetic-, ultrasound-, enzyme-, light-and electric-responsive systems are extensively discussed. Finally, some indications concerning the possibilities of multi-responsive systems are discussed.Postprint (published version

Feminization of benzodiazepine use

Partiendo de la observación experiencial de un alto consumo de benzodiacepinas (BZP) entre las mujeres, el objetivo de este estudio es analizar los conocimientos y las prácticas de su uso entre las mujeres de Deltebre y qué lleva a los profesionales a iniciar y mantener su prescripción. Se realizó un grupo de discusión con mujeres consumidoras y entrevistas a facultativas con perspectiva etnográfica.Desde la biomedicina no se atienden los factores psicosociales que generan los malestares en estas mujeres, produciendo una farmacologización, la pérdida del agency (capacidad de actuar) y la cosificación de los mismos. Existe una ausencia de reciprocidad en sus contextos, contribuyendo a la crisis de la presencia, la cual activa la búsqueda de sustitutos e inicia el consumo de BZP. Sin embargo, ésta no produce la restitución, llevando a la cronificación del consumo.Se plantea incorporar los saberes de las mujeres consumidoras en el abordaje de los tratamientos con BZP desde la atención primaria de salud, lo cual permite llegar a un conocimiento más profundo del problema y construir espacios de reconstrucción y restitución de las reciprocidades, que conlleve una verdadera superación de la crisis de la presencia y al abandono del fármaco.Based on the experiential observation of a high consumption of benzodiazepines (BZP) among women, the aim of this study is to analyze the knowledge and practice of BZP use among women of Deltebre and that leads professionals to initiate and maintain their prescription. A discussion group with female consumers and interviews with physicians with an ethnographic perspective were carried out.Biomedicine does not address the psychosocial factors that generate the discomfort of these women, producing a pharmacologization, the loss of agency and the reification of the same. There is an absence of reciprocity in their contexts, contributing to the crisis of presence, which activates the search for substitutes and initiates the consumption of BZP But it does not produce restitution, which brings us the chronification of consumption.It is proposed to incorporate the knowledge of the women in the approach of the treatments with BZP from the primary health care, which allows to arrive at a deeper knowledge of the problem and to construct spaces of reconstruction and restitution of the reciprocities that entails a true overcoming of the crisis of the presence and the abandonment of the drug

Temperature induced structural changes in even-odd nylons with long polymethylene segments

Structural transitions of nylons 8 9 and 12 9 heating and cooling processes were investigated using calorimetric, spectroscopic during and real time X-ray diffraction data. These even-odd nylons had three polymorphic forms related to structures where hydrogen bonds were established in two planar directions. Heating processes showed a first structural transition at low temperature where the two strong reflections related to the packing mode of the low temperature structure (form I) disappeared instead of moving together and merging into a single reflection, as observed for conventional even-even nylons. The high temperature structure corresponded to a typical pseudohexagonal packing (form III) attained after the named Brill transition temperature. Structural transitions were not completely reversible since an intermediate structure (form II) became clearly predominant at room temperature in subsequent cooling processes. A single spherulitic morphology with negative birefringence and a flat-on edge-on lamellar disposition was obtained when the two studied polyamides crystallized from the melt state. Kinetic analyses indicated that both nylons crystallized according to a single regime and a thermal nucleation. Results also pointed out a secondary nucleation constant for nylon 12 9 higher than that for nylon 8 9, suggesting greater difficulty in crystallizing when the amide content decreased. © 2016 Wiley Periodicals, Inc. J. Polym. Sci., Part B: Polym. Phys. 2016, 54, 2494–2506Peer ReviewedPostprint (author's final draft

Nylons with applications in energy generators, 3D printing and biomedicine

Linear polyamides, known as nylons, are a class of synthetic polymers with a wide range of applications due to their outstanding properties, such as chemical and thermal resistance or mechanical strength. These polymers have been used in various fields: from common and domestic applications, such as socks and fishing nets, to industrial gears or water purification membranes. By their durability, flexibility and wear resistance, nylons are now being used in addictive manufacturing technology as a good material choice to produce sophisticated devices with precise and complex geometric shapes. Furthermore, the emergence of triboelectric nanogenerators and the development of biomaterials have highlighted the versatility and utility of these materials. Due to their ability to enhance triboelectric performance and the range of applications, nylons show a potential use as tribo-positive materials. Because of the easy control of their shape, they can be subsequently integrated into nanogenerators. The use of nylons has also extended into the field of biomaterials, where their biocompatibility, mechanical strength and versatility have paved the way for groundbreaking advances in medical devices as dental implants, catheters and non-absorbable surgical sutures. By means of 3D bioprinting, nylons have been used to develop scaffolds, joint implants and drug carriers with tailored properties for various biomedical applications. The present paper aims to collect evidence of these recently specific applications of nylons by reviewing the literature produced in recent decades, with a special focus on the newer technologies in the field of energy harvesting and biomedicine.Peer ReviewedPostprint (published version

Incorporation of biguanide compounds into poly(GL)-b-poly(GL-co-TMC-co-CL)-b-poly(GL) monofilament surgical sutures

A new biodegradable coating was developed for bioabsorbable monofilament sutures. Specifically, a random copolymer having 35 wt-% and 65 wt-% of lactide and trimethylene carbonate units showed appropriate flexibility, stickiness and degradation rate, as well as capability to produce a complete and uniform coating. Monofilament sutures of polyglycolide-b-poly(glycolide-co-trimethylene carbonate-co-e-caprolactone)-b-polyglycolide were loaded with chlorhexidine (CHX) and poly(hexamethylene biguanide) (PHMB) to explore the possibility to achieve antimicrobial activity without adverse cytotoxic effects. To this end, two processes based on single drug adsorption onto the suture surface and incorporation into the coating copolymer were used and subsequently evaluated. Although the second process could be considered more complex, clear benefits were observed in terms of drug loading efficiency, antimicrobial effect and even lack of cytotoxicity. In general, drugs could be loaded in an amount leading to a clear bacteriostatic effect for both Gram-negative and Gram-positive bacteria without causing significant cytotoxicity. Release profiles of PHMB and CHX were clearly different. Specifically, adsorption of the drug onto the fiber surface which prevented complete release was detected for PHMB. This polymer had advantages derived from its high molecular size, which hindered penetration into cells, thus resulting in lower cytotoxicity. Furthermore, bacterial growth kinetics measurements and bacterial adhesion assays showed greater effectiveness of this polymer.Peer ReviewedPostprint (author's final draft

Implementación de la técnica de análisis literario para desarrollar la creatividad de los estudiantes de Bachillerato Internacional de la Unidad Educativa Dolores Sucre, 2018

Este estudio consideró el implementar la técnica de análisis literario para el desarrollo del pensamiento creativo de los estudiantes del 2do. Bachillerato Internacional, porque se evidenció que los alumnos tenían poco análisis, criticidad, reflexividad entre otros; el objetivo general del estudio es: Implementar adecuadamente la técnica de análisis literario para que se desarrollen niveles de creatividad en los estudiantes del Segundo Bachillerato Internacional de la Unidad Educativa Dolores Sucre – 2018. En cuanto al diseño es de tipo pre - experimental, descriptiva y cuantitativa; la muestra fue de 30 estudiantes que pertenecen al 2do, de Bachillerato Internacional, el instrumento de que se aplicó fue un cuestionario, cabe recalcar que se realizó una prueba piloto para comprobar la validez del instrumento. Entre los resultados más relevantes que se obtuvieron están: Al implementar la técnica de análisis literario se pudo observar que los estudiantes tuvieron adelantos importantes, más que nada en la desmotivación de no poder efectuar un análisis lógico y coherente con respecto a la obra literaria leída y expresada de manera oral o escrita. Esto se evidenció porque al obtener resultados se pudo concluir que la técnica de análisis literario influye significativamente en el desarrollo de la creatividad en los estudiantes del Segundo Bachillerato Internacional de la Unidad Educativa Dolores Sucre – 2018, lo que queda determinado con la aplicación de la prueba T- Student cuyo nivel de significancia es menor a 0,05 con lo que se acepta la hipótesis de trabajo

Evaluación del beneficio tecnológico y económico de la aplicación de fibra de Bambú en hamburguesa

Universidad Nacional Agraria La Molina. Facultad de Industrias Alimentarias. Departamento Académico de Ingeniería de Alimentos y Productos AgropecuariosSe realizó un estudio sobre la aplicación de la fibra de bambú en hamburguesa con el objetivo de reducir el contenido de carne en la formulación estándar sin que existan diferencias significativas en la fórmula propuesta con el uso del nuevo ingrediente. Se sometieron dos tipos de fibra de bambú a pruebas y se determinó que con Sanacel® Bamboo 1000 se logró obtener una formula con una reducción de carne de 22.4 por ciento, siendo 20.37 por ciento más económica que la fórmula estándar, sin que se viera afectada la calidad sensorial del producto, por el contrario, mejorando la misma al tener una pérdida por cocción 53.7 por ciento menor que en la fórmula estándar.A study was carried out on the application of bamboo fiber in hamburger with the objective of reducing the meat content in the standard formulation without significant differences in the proposed formula with the use of the new ingredient. Two types of bamboo fiber were subjected to tests and it was determined that with Sanacel® Bamboo 1000 it was possible to obtain a formula with a reduction of meat of 22.4 percent, being 20.37 percent cheaper than the standard formula, without being affected the sensory quality of the product, on the contrary, improving it by having a loss on cooking 53.7 percent lower than in the standard formula

Facultad de los árbitros para dictar y ejecutar medidas cautelares dentro del procedimiento arbitral

El presente trabajo tiene como finalidad primera, efectuar un estudio en detalle respecto a las facultades jurisdiccionales de las cuales se enviste al Tribunal Arbitral en un proceso de arbitraje de manera particular, para disponer medidas cautelares. El primer escollo lo encontramos al no tener el reconocimiento de poder facultárseles para que la ejecución de tales medidas sea coherente con la facultad de Dirigir el proceso Arbitral, ateniéndonos al principio general de derecho "De quien puede lo más puede lo menos" y por tanto se encuentre a cargo de los árbitros constituidos en Tribunal, todo esto, dentro del proceso como en Derecho corresponde. Lamentablemente, las partes para poder acceder a la ejecución de las medidas cautelares se ven en la necesidad de recurrir a la justicia ordinaria en un procedimiento que distrae la causa –al menos momentáneamente- del seno de su jurisdicción propia, trayendo como consecuencia además de una desnaturalización del proceso de ejecución, una dilación innecesaria y desgaste del sistema de administración de justicia ordinaria, pese a que la jurisdicción arbitral es exclusiva, excluyente y autónoma. Pese a todo lo expresado no se produce como consecuencia de esta situación, ninguna renuncia, modificación o reforma al convenio arbitral

Incidencia del alcoholismo y drogadicción en el desarrollo intelectual y emocional del adolescente.

El objetivo de la investigación fue, identificar las causas que impiden la superación del adolescente que consume alcohol y drogas. El estudio se realizó en el centro de Alcohólicos Anónimos “Fe por 24 horas”, durante el año 2015. El tipo de muestreo que se utilizó para seleccionar la muestra fue intencional. La muestra estuvo integrada por veinte adolescentes, mujeres y hombres, comprendidos entre diecisiete y diecinueve años de edad, que residen en la colonia el Edén zona 5 y asisten al centro de Alcohólicos Anónimos “Fe por 24 horas”. Para recolectar datos se utilizaron las técnicas siguientes: observación, entrevistas, y talleres. Los instrumentos que se utilizaron fueron: consentimiento informado, guía de observación estructurada y participante, guía de entrevistas, ficha técnica y talleres informativos. Concluyó que, el alcoholismo y la drogadicción inciden en el desarrollo emocional e intelectual del adolescente al presentar conductas de desinterés, apatía, falta de creatividad, baja autoestima, agresividad, pasividad y rechazo. A nivel intelectual se presentó deterioro de atención, memoria y concentración, sueño excesivo y falta de alimentación adecuada