Estudio y propuesta de las instalaciones deportivas necesarias para el óptimo desarrollo de las cualidades físicas de una unidad de infantería.

Este trabajo de fin de grado perteneciente al módulo de Recursos Humanos busca dar solución a uno de los problemas que lleva arrastrando el Regimiento desde hace tiempo, a saber, la falta de instalaciones y material para la adecuada preparación física de los soldados, hay que sumarle la falta de presupuesto y un gran número de personas realizando formación física a la misma hora.Estos problemas crean un efecto dominó empezando con un mayor número de lesiones del personal que le impide desarrollar su trabajo causando baja en la sección, con la especialización que se ha llevado a cabo en el ejército hace que cada soldado sea muy importante dentro de la sección, si este soldado causa baja y es conductor del vehículo el jefe de sección podría contar con un vehículo menos para sus maniobras o que le falten el tirador dentro del vehículo, y ya no solo eso, puede ocurrir que el soldado pierda la motivación por volver a trabajar por miedo a recaer en su lesión.Con este proyecto se pretende conseguir una mejora de la calidad de vida de los soldados, por un lado, reduciendo el número de lesiones que se producen al año, y por otro lado aumentando la motivación y las ganas de mejorar su condición física. También va a permitir reducir las aglomeraciones que se producen en el resto de instalaciones del acuartelamiento. Todo ello ajustándose al presupuesto que tiene la unidad para la adquisición de nuevo material.Por tanto, el objetivo de este trabajo es hacer una propuesta de una instalación deportiva o una compra de material deportivo para que una unidad del tipo sección (30 personas) pueda realizar su preparación física. <br /

Identification of candidate genes for reproductive traits in cattle using a functional interaction network approach

Reproduction is a key element in cattle production systems. Systems biology approaches, including those involving gene networks, have been applied to genetic dissection complex phenotypes in cattle. A set of 385 genes associated with reproductive traits in cattle were included in a protein-protein network analysis to identify and prioritize candidate genes related to phenotypic differences in cattle reproduction. Genes belonging to the ubiquitin family - Ubiquitin C (Ubc, Gene ID: 444874) and Ubiquitin B (Ubb, Gene ID: 281370) -had the highest probability of being associated with these traits in cattle. Both proteins were identified as important hubs in a protein-protein interaction network, each having 3,775 interactions of 3,856 possible. Resequencing of the Ubb gene coding region to evaluate the presence of SNPs in a discovery population identified the G/T (rs110366695) transversion. This causes emergence of a stop codon and a protein truncated by 287 aa. The allelic frequency distributions found in two beef cattle breeds highlight the promise of further research into the effects of protein truncation and the potential of these proteins as molecular markers for semen quality

Biocontrol of Fusarium oxysporum by Trichoderma spp. in Aloe vera under greenhouse and field conditions

&nbsp;During the last decade, an increase in the incidence of the fungus Fusarium oxysporum in aloe [Aloe vera (L.) Burm.f.] plants has been observed, reducing the national production by 14%. A study was conducted to evaluate five native strains of Trichoderma against F. oxysporum in A. vera plants, under greenhouse and field conditions. The experiment in the greenhouse consisted of evaluating 1-year-old A. vera plants, which were inoculated in the root with a suspension of 10 mL of 1&times;108 conidia of Trichoderma spp. This experiment consisted of six treatments with ten repetitions; five strains of Trichoderma spp. and the control (without chemical treatment). The evaluation in field was conducted for one year (2016-17) to test five strains of Trichoderma spp. and the control (without chemical treatment), under a randomized complete block design with five replications. The evaluation under greenhouse conditions showed that when A. vera plants were treated with Trichoderma asperellum, the lowest incidence (5%) of F. oxysporum was observed and plants had the highest number of leaves than the rest of the treatments with 0.9% of total solids. Under greenhouse conditions, plants inoculated with Trichoderma asperellum and T. harzianum reduced the incidence of F. oxysporum by 30% and 40%, respectively. In the field, when evaluating T. asperellum, a lower incidence (9%) of F. oxysporum was observed in A. vera plants, and the leaves showed 0.9% of total solids. The plants inoculated with T. asperellum and T. harzianum decreased the incidence of the phytopathogen by 40% and 50%, respectively.&nbsp; In addition, an increase was observed in plant height, number of leaves, total solids, weight of root and leaves of A. vera with different Trichoderma species both under greenhouse and field conditions.&nbsp

Identification of candidate genes and SNPs related to cattle temperament using a GWAS analysis coupled with an interacting network analysis

El objetivo de este estudio fue identificar en animales de raza Angus y Brangus con temperamento extremo, medido como velocidad de salida, regiones genómicas y genes candidatos asociados con el temperamento bovino. La población fue genotipada con el chip Genomic Profiler HD 150K y después del análisis de asociación del genoma completo, los SNP rs133956611 (P= 2.65 E-06) y rs81144933 (P= 9.58 E-06) se asociaron con el temperamento. El análisis de mapeo de las regiones cercanas al SNP rs81144933 identificó los genes SNCA (alfa-sinucleína) y MMRN1 (multimerin-1) a 222.8 y 435.9 Kb corriente abajo, respectivamente, mientras que para los loci rs133956611 se identificó el gen GPRIN3 (familia GPRIN- miembro 3) a 245.7 Kb corriente arriba, los tres genes se encuentran en el cromosoma BTA6. El análisis de las interacciones proteína-proteína de SNCA permitió la identificación de los genes APP (proteína precursora de β-amiloide), PARK7 (deglicasa asociada al parkinsonismo), UCHL1 (ubiquitina C-terminal hidrolasa L1), PARK2 (parkina-RBR-E3-ubiquitina-proteína-ligasa), y genes de la familia SLC como candidatos a estar asociados con el temperamento bovino. Todos estos genes candidatos y su interacción fueron resecuenciados, lo que permitió el descubrimiento de nuevos SNP en los genes SNCA y APP. De estos, los SNP localizados en los intrones 5, 8 y 11 del gen APP afectan a los motivos del sitio de empalme. Estos resultados indican que el SNCA y sus genes interactuantes son candidatos para estar relacionados con el temperamento bovino.The objective of this study was to identify in Angus and Brangus breed animals with extreme temperament, measured as exit velocity, genomic regions and candidate genes associated with bovine temperament. The population was genotyped with the Genomic Profiler HD 150K chip and after the genome-wide association analysis, the SNPs rs133956611 (P=2.65 E-06) and rs81144933 (P=9.58 E-06) were associated with temperament. The mapping analysis of the regions close to the SNP rs81144933 identified the SNCA (alpha-synuclein) and MMRN1 (multimerin-1) genes at 222.8 and 435.9 Kb downstream respectively, while for the rs133956611 loci the gene GPRIN3 (GPRIN family-member-3) was identified at 245.7 Kb upstream, all three genes are located on the BTA6 chromosome. The analysis of SNCA protein-protein interactions allowed the identification of the genes APP (β-amyloid precursor protein), PARK7 (parkinsonism-associated-deglycase), UCHL1 (ubiquitin-C-terminal-hydrolase-L1), PARK2 (parkin-RBR- E3-ubiquitin-protein-ligase), and genes of the SLC family as candidates to be associated with bovine temperament. All these candidate genes and their interacting were resequenced, which allowed the discovery of new SNPs in the SNCA and APP genes. Of these, the SNPs located in introns 5, 8 and 11 of the APP gene affect splicing site motifs. These results indicate that SNCA and its interacting genes are candidates to be related to bovine temperament

Desarrollo y aplicación de una metodología innovadora para realizar visitas técnicas virtuales a empresas y centros de investigación

El objetivo del proyecto es desarrollar una metodología innovadora para realizar visitas técnicas virtuales a plantas industriales y/o centros de investigación con alumnos que podrán utilizarse en 8 asignaturas de 4 grados y 2 másteres de la UCM.FALSEVicerrectorado de Calidad Proyectos de Innovación (2021-2022) Innova-Docenciasubmitte

Infectious Diseases, Social, Economic and Political Crises, Anthropogenic Disasters and Beyond: Venezuela 2019 – Implications for Public Health and Travel Medicine

During last months, there have been a significant increase in the evidences showing the catastrophic health situation in Venezuela. There are multiple epidemics, increase in emerging and reemerging infectious, tropical and parasitic diseases as consequences of the social, economic and political crises, which would be considered today a clearly anthropogenic disaster. Venezuela is facing in 2019, the worse sanitary conditions, with multiple implications for public health and travel medicine. So far, from a global perspective, this situation will be an impediment for the achievement of the sustainable development goals (SDG) in 2030. In this multiauthor review, there is a comprehensive analysis of the situation for infectious diseases, non-communicable diseases, their impact in the Americas region, given the migration crisis as well as the comparative status of the SDG 2030. This discussion can provide input for prioritizing emerging health problems and establish a future agenda

Infectious Diseases, Social, Economic and Political Crises, Anthropogenic Disasters and Beyond: Venezuela 2019 – Implications for Public Health and Travel Medicine

During last months, there have been a significant increase in the evidences showing the catastrophic health situation in Venezuela. There are multiple epidemics, increase in emerging and reemerging infectious, tropical and parasitic diseases as consequences of the social, economic and political crises, which would be considered today a clearly anthropogenic disaster. Venezuela is facing in 2019, the worse sanitary conditions, with multiple implications for public health and travel medicine. So far, from a global perspective, this situation will be an impediment for the achievement of the sustainable development goals (SDG) in 2030. In this multiauthor review, there is a comprehensive analysis of the situation for infectious diseases, non-communicable diseases, their impact in the Americas region, given the migration crisis as well as the comparative status of the SDG 2030. This discussion can provide input for prioritizing emerging health problems and establish a future agenda