MoMoWo Symposium 2018

The stimulating four-day Symposium of the successful MoMoWo European project, co-funded by the Creative Europe Programme of the European Union, and organised by International Coordinators Caterina Franchini (DIST) and Emilia Garda (DISEG) closed at the Campus Lingotto of Politecnico di Torino the 16th June 2018. It has been an outstanding cultural and educational opportunity for international scholars, students as well as for professional architects and engineers. After almost 19 months of a large variety project activities, this Symposium continued to increase the visibility of creative women, to foster in Europe and beyond, interdisciplinary and multicultural approaches to the study of the built environment and to facilitate the exchange of research results and professional practices in the different fields of architecture, civil engineering and design

MoMoWo Symposium 2018. Women's Creativity since the Modern Movement (1918-2018): Toward a New Perception and Reception. Programme and Abstract of the International Conference

Il volume raccoglie gli abstract e contiene il programma del Convegno Internazionale finale MoMoWo organizzato dalle curatrici stesse. I contributi, selezionati dal Comitato Scientifico internazionale di MoMoWo, sono l’esito di una call for paper che ha visto la partecipazione di 203 autori, afferenti a 135 istituzioni di 35 Paesi, per un totale di 152 contributi, ripartiti su 7 Topic (A-G)

A Helpline Telephone Service for Tobacco Related Issues: The Italian Experience

Antismoking helplines have become an integral part of tobacco control efforts in many countries, including Italy. The demonstrated efficacy and the convenience of telephone based counselling have led to the fast adoption of antismoking helplines. However, information on how these helplines operate in actual practice is not often readily available. This paper provides an overview of the Italian Antismoking Helpline, an increasingly popular telephone service for tobacco problems operating in Italy since 2000. As many states, regions and nations are contemplating various telephone programs as part of large scale anti-tobacco campaigns, this paper briefly discusses the reasons the helpline is well suited to lead the cessation component of a comprehensive tobacco control program, how it operates and how it can be used in conjunction with other tobacco control activities. The Italian Antismoking Helpline provides Italians with free services that include counselling, cessation related information, self help quit kits and current legislation information. The helpline is promoted statewide by media campaigns, health care providers, local tobacco control programs and public school system. The Helpline is centrally operated through the Istituto Superiore di Sanità and it has served over 17.000 tobacco users and others

A multimodal imaging approach to the evaluation of post-traumatic epilepsy

Electroencephalography-functional magnetic resonance imaging (EEG-fMRI) coregistration and high-density EEG (hdEEG) can be combined to map noninvasively abnormal brain activation elicited by epileptic processes. By combining noninvasive imaging techniques in a multimodal approach, we sought to investigate pathophysiological mechanisms underlying epileptic activity in seven patients with severe traumatic brain injury

Low risk of seizures with slow flumazenil infusion and routine anticonvulsant prophylaxis for high-dose benzodiazepine dependence

High-dose benzodiazepine (BZD) dependence represents an emerging and under-reported addiction phenomenon and is associated with reduced quality of life. To date there are no guidelines for the treatment of high-dose BZD withdrawal. Low-dose slow flumazenil infusion was reported to be effective for high-dose BZD detoxification, but there is concern about the risk of convulsions during this treatment. We evaluated the occurrence of seizures in 450 consecutive high-dose BZD dependence patients admitted to our unit from April 2012 to April 2016 for detoxification with low-dose slow subcutaneous infusion of flumazenil associated with routine anticonvulsant prophylaxis. In our sample, 22 patients (4.9%) reported history of convulsions when previously attempting BZD withdrawal. Only four patients (0.9%) had seizures during ( n = 2) or immediately after ( n = 2) flumazenil infusion. The two patients with seizures during flumazenil infusion were poly-drug misusers. The most common antiepileptic drugs (AEDs) used for anticonvulsant prophylaxis were either valproate 1000 mg or levetiracetam 1000 mg. Our data indicate that, when routinely associated with AEDs prophylaxis, low-dose slow subcutaneous flumazenil infusion represents a safe procedure, with low risk of seizure occurrence

Lymphomatosis cerebri and anti-NMDAR antibodies: A unique constellation

Letter to the Edito

IER-START nomogram for prediction of three-month unfavorable outcome after thrombectomy for stroke

BACKGROUND: The applicability of the current models for predicting functional outcome after thrombectomy in strokes with large vessel occlusion (LVO) is affected by a moderate predictive performance. AIMS: We aimed to develop and validate a nomogram with pre- and post-treatment factors for prediction of the probability of unfavorable outcome in patients with anterior and posterior LVO who received bridging therapy or direct thrombectomy <6 h of stroke onset. METHODS: We conducted a cohort study on patients data collected prospectively in the Italian Endovascular Registry (IER). Unfavorable outcome was defined as three-month modified Rankin Scale (mRS) score 3-6. Six predictors, including NIH Stroke Scale (NIHSS) score, age, pre-stroke mRS score, bridging therapy or direct thrombectomy, grade of recanalization according to the thrombolysis in cerebral ischemia (TICI) grading system, and onset-to-end procedure time were identified a priori by three stroke experts. To generate the IER-START, the pre-established predictors were entered into a logistic regression model. The discriminative performance of the model was assessed by using the area under the receiver operating characteristic curve (AUC-ROC). RESULTS: A total of 1802 patients with complete data for generating the IER-START was randomly dichotomized into training ( n = 1219) and test ( n = 583) sets. The AUC-ROC of IER-START was 0.838 (95% confidence interval [CI]): 0.816-0.869) in the training set, and 0.820 (95% CI: 0.786-0.854) in the test set. CONCLUSIONS: The IER-START nomogram is the first prognostic model developed and validated in the largest population of stroke patients currently candidates to thrombectomy which reliably calculates the probability of three-month unfavorable outcome

Functional and radiological outcomes after bridging therapy versus direct thrombectomy in stroke patients with unknown onset

We aimed to assess functional and radiological outcomes after bridging therapy (intravenous thrombolysis plus mechanical thrombectomy, MT) vs direct MT in unknown onset stroke patients