3 research outputs found
Structure and absolute growth of a population of <em>Hippolyte inermis</em> Leach 1815 (Decapoda: Caridea) from <em>Zostera marina</em> (L.) meadows (Malaga, southern Spain)
Biochemical investigation of the effects of human platelet releasates on human articular chondrocytes
The aim of the present study was to demonstrate the mitogenic and differentiating properties of platelet-rich plasma releasates (PRPr) on human chondrocytes in mono- and three-dimensional cultures. In order to assess if PRPr supplementation could maintain the chondrocyte phenotype or at least inhibit the cell de-differentiation even after several days in culture, we performed a proteomic study on several cell cultures independently grown, for different periods of time, in culture medium with FCS, human serum (HS), and releasates obtained from PRP and platelet-poor plasma (PPP). We found that PRP treatment actually induced in chondrocytes the expression of proteins (some of which novel) involved in differentiation