The application of LANDSAT remote sensing technology to natural resources management. Section 1: Introduction to VICAR - Image classification module. Section 2: Forest resource assessment of Humboldt County.

A teaching module on image classification procedures using the VICAR computer software package was developed to optimize the training benefits for users of the VICAR programs. The field test of the module is discussed. An intensive forest land inventory strategy was developed for Humboldt County. The results indicate that LANDSAT data can be computer classified to yield site specific forest resource information with high accuracy (82%). The "Douglas-fir 80%" category was found to cover approximately 21% of the county and "Mixed Conifer 80%" covering about 13%. The "Redwood 80%" resource category, which represented dense old growth trees as well as large second growth, comprised 4.0% of the total vegetation mosaic. Furthermore, the "Brush" and "Brush-Regeneration" categories were found to be a significant part of the vegetative community, with area estimates of 9.4 and 10.0%

Radiolysis of Macromolecular Organic Material in Mars-Relevant Mineral Matrices

The fate of organic material on Mars after deposition is crucial to interpreting the source of these molecules. Previous work has addressed how various organic compounds at millimeter depths in sediments respond to ultraviolet radiation. In contrast, this study addressed how highenergy particle radiation (200MeV protons, simulating the effect of galactic cosmic rays and solar wind at depths of <45 cm) inuences organic macromolecules in sediments. Specically, we report the generation of organicacid radiolysis products after exposure to radiation doses equivalent to geological time scales (17 Myr). We found that formate and oxalate were produced from a variety of organic starting materials and mineral matrices. Unlike ultravioletdriven reactions that can invoke Fenton chemistry to produce organic acids, our work suggests that irradiation of semiconductor surfaces, such as TiO2 or possible clay minerals found on Mars, forms oxygen and hydroxyl radical species, which can break down macromolecules into organic acids. We also investigated the metastability of benzoate in multiple mineral matrices. Benzoate was added to samples prior to irradiation and persisted up to 500 kGys of exposure. Our ndings suggest that organic acids are likely a major component of organic material buried at depth on Mars

America's health care problem: an economic perspective

Soaring health care expenditures and the large number of uninsured Americans-now estimated at 35 million-have received much public attention in recent years. The widespread concerns have led to demands for substantial reform of the U.S. health care system. ; Beverly Fox, Lori Taylor, and Mine Yucel identify several distortions in the current health care system that may be contributing to overconsumption of health care by some and underconsumption of health care by others, and thus may be leading to excessively high expenditures and the problems of the uninsured. These distortions include tax subsidies for employer-provided health insurance, regulations and industry practices that restrict the supply of health care professionals, and the noncompetitive nature of the health insurance industry. Effective health care reform must address these distortions rather than nondistortionary elements of the system, such as producer and consumer uncertainty and the changing demographic composition of the U.S. population.Medical care

Experimental study of wing leading-edge devices for improved maneuver performance of a supercritical maneuvering fighter configuration

Wind tunnel tests were conducted to examine the use of wing leading-edge devices for improved subsonic and transonic maneuver performance. These devices were tested on a fighter configuration which utilized supercritical-wing technology. The configuration had a leading-edge sweep of 45 deg and an aspect ratio of 3.28. The tests were conducted at Mach numbers of 0.60 and 0.85 with angles of attack from -0.5 deg to 22 deg. At both Mach numbers, sharp leading-edge flaps produced vortices which greatly altered the flow pattern on the wing and resulted in substantial reductions in drag at high lift. Underwing or pylon-type vortex generators also reduced drag at high lift. The vortex generators worked better at a Mach number of 0.60. The vortex generators gave the best overall results with zero toe-in angle and when mounted on either the outboard part of the wing or at both an outboard location and halfway out the semispan. Both the flaps and the vortex generators had a minor effect on the pitching moment. Fluorescent minitufts were found to be useful for flow visualization at transonic maneuver conditions

Complex Systems Science: Dreams of Universality, Reality of Interdisciplinarity

Using a large database (~ 215 000 records) of relevant articles, we empirically study the "complex systems" field and its claims to find universal principles applying to systems in general. The study of references shared by the papers allows us to obtain a global point of view on the structure of this highly interdisciplinary field. We show that its overall coherence does not arise from a universal theory but instead from computational techniques and fruitful adaptations of the idea of self-organization to specific systems. We also find that communication between different disciplines goes through specific "trading zones", ie sub-communities that create an interface around specific tools (a DNA microchip) or concepts (a network).Comment: Journal of the American Society for Information Science and Technology (2012) 10.1002/asi.2264

Structural plasticity underlies experience-dependent functional plasticity of cortical circuits

The stabilization of new spines in the barrel cortex is enhanced after whisker trimming, but its relationship to experience-dependent plasticity is unclear. Here we show that in wild-type mice, whisker potentiation and spine stabilization are most pronounced for layer 5 neurons at the border between spared and deprived barrel columns. In homozygote alphaCaMKII-T286A mice, which lack experience-dependent potentiation of responses to spared whiskers, there is no increase in new spine stabilization at the border between barrel columns after whisker trimming. Our data provide a causal link between new spine synapses and plasticity of adult cortical circuits and suggest that alphaCaMKII autophosphorylation plays a role in the stabilization but not formation of new spines

Blobs in Wolf-Rayet Winds: Random Photometric and Polarimetric Variability

Some isolated Wolf-Rayet stars present random variability in their optical flux and polarization. We make the assumption that such variability is caused by the presence of regions of enhanced density, i.e. blobs, in their envelopes. In order to find the physical characteristics of such regions we have modeled the stellar emission using a Monte Carlo code to treat the radiative transfer in an inhomogeneous electron scattering envelope. We are able to treat multiple scattering in the regions of enhanced density as well as in the envelope itself. The finite sizes of the source and structures in the wind are also taken into account. Most of the results presented here are based on a parameter study of models with a single blob. The effects due to multiple blobs in the envelope are considered to a more limited extent. Our simulations indicate that the density enhancements must have a large geometric cross section in order to produce the observed photopolarimetric variability. The sizes must be of the order of one stellar radius and the blobs must be located near the base of the envelope. These sizes are the same inferred from the widths of the sub-peaks in optical emission lines of Wolf-Rayet stars. Other early-type stars show random polarimetric fluctuations with characteristics similar to those observed in Wolf-Rayet stars, which may also be interpreted in terms of a clumpy wind. Although the origin of such structures is still unclear, the same mechanism may be working in different types of hot stars envelopes to produce such inhomogeneities.Comment: Accepted to ApJ. 17 pages + 6 figure

Genome-Wide Association with Diabetes-Related Traits in the Framingham Heart Study

BACKGROUND: Susceptibility to type 2 diabetes may be conferred by genetic variants having modest effects on risk. Genome-wide fixed marker arrays offer a novel approach to detect these variants. METHODS: We used the Affymetrix 100K SNP array in 1,087 Framingham Offspring Study family members to examine genetic associations with three diabetes-related quantitative glucose traits (fasting plasma glucose (FPG), hemoglobin A1c, 28-yr time-averaged FPG (tFPG)), three insulin traits (fasting insulin, HOMA-insulin resistance, and 0–120 min insulin sensitivity index); and with risk for diabetes. We used additive generalized estimating equations (GEE) and family-based association test (FBAT) models to test associations of SNP genotypes with sex-age-age2-adjusted residual trait values, and Cox survival models to test incident diabetes. RESULTS: We found 415 SNPs associated (at p 1%) 100K SNPs in LD (r2 > 0.05) with ABCC8 A1369S (rs757110), KCNJ11 E23K (rs5219), or SNPs in CAPN10 or HNFa. PPARG P12A (rs1801282) was not significantly associated with diabetes or related traits. CONCLUSION: Framingham 100K SNP data is a resource for association tests of known and novel genes with diabetes and related traits posted at. Framingham 100K data replicate the TCF7L2 association with diabetes.National Heart, Lung, and Blood Institute's Framingham Heart Study (N01-HC-25195); National Institutes of Health National Center for Research Resources Shared Instrumentation grant (1S10RR163736-01A1); National Center for Research Resources General Clinical Research Center (M01-RR-01066); American Diabetes Association Career Developement Award; GlaxoSmithKline; Merck; Lilly; National Institutes of Health Research Career Award (K23 DK659678-03