39 research outputs found
Uso de modelos lineares mistos na avaliação genética de escores visuais: estudo de simulação
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The Galaxy platform for accessible, reproducible, and collaborative data analyses: 2024 update
YesGalaxy (https://galaxyproject.org) is deployed globally, predominantly through free-to-use services, supporting user-driven research that broadens in scope each year. Users are attracted to public Galaxy services by platform stability, tool and reference dataset diversity, training, support and integration, which enables complex, reproducible, shareable data analysis. Applying the principles of user experience design (UXD), has driven improvements in accessibility, tool discoverability through Galaxy Labs/subdomains, and a redesigned Galaxy ToolShed. Galaxy tool capabilities are progressing in two strategic directions: integrating general purpose graphical processing units (GPGPU) access for cutting-edge methods, and licensed tool support. Engagement with global research consortia is being increased by developing more workflows in Galaxy and by resourcing the public Galaxy services to run them. The Galaxy Training Network (GTN) portfolio has grown in both size, and accessibility, through learning paths and direct integration with Galaxy tools that feature in training courses. Code development continues in line with the Galaxy Project roadmap, with improvements to job scheduling and the user interface. Environmental impact assessment is also helping engage users and developers, reminding them of their role in sustainability, by displaying estimated CO2 emissions generated by each Galaxy job.NIH [U41 HG006620, U24 HG010263, U24 CA231877, U01 CA253481]; US National Science Foundation [1661497, 1758800, 2216612]; computational resources are provided by the Advanced Cyberinfrastructure Coordination Ecosystem (ACCESS-CI), Texas Advanced Computing Center, and the JetStream2 scientific cloud. Funding for open access charge: NIH. ELIXIR IS and Travel grants; EU Horizon Europe [HORIZON-INFRA-2021-EOSC-01-04, 101057388]; EU Horizon Europe under the Biodiversity, Circular Economy and Environment program (REA.B.3, BGE 101059492); German Federal Ministry of Education and Research, BMBF [031 A538A de.NBI-RBC]; Ministry of Science, Research and the Arts Baden-Württemberg (MWK) within the framework of LIBIS/de.NBI Freiburg. Galaxy Australia is supported by the Australian BioCommons which is funded through Australian Government NCRIS investments from Bioplatforms Australia and the Australian Research Data Commons, as well as investment from the Queensland Government RICF program.Please note, contributors are listed in alphabetical order
Recommended from our members
The Galaxy platform for accessible, reproducible, and collaborative data analyses: 2024 update
YesGalaxy (https://galaxyproject.org) is deployed globally, predominantly through free-to-use services, supporting user-driven research that broadens in scope each year. Users are attracted to public Galaxy services by platform stability, tool and reference dataset diversity, training, support and integration, which enables complex, reproducible, shareable data analysis. Applying the principles of user experience design (UXD), has driven improvements in accessibility, tool discoverability through Galaxy Labs/subdomains, and a redesigned Galaxy ToolShed. Galaxy tool capabilities are progressing in two strategic directions: integrating general purpose graphical processing units (GPGPU) access for cutting-edge methods, and licensed tool support. Engagement with global research consortia is being increased by developing more workflows in Galaxy and by resourcing the public Galaxy services to run them. The Galaxy Training Network (GTN) portfolio has grown in both size, and accessibility, through learning paths and direct integration with Galaxy tools that feature in training courses. Code development continues in line with the Galaxy Project roadmap, with improvements to job scheduling and the user interface. Environmental impact assessment is also helping engage users and developers, reminding them of their role in sustainability, by displaying estimated CO2 emissions generated by each Galaxy job.NIH [U41 HG006620, U24 HG010263, U24 CA231877, U01 CA253481]; US National Science Foundation [1661497, 1758800, 2216612]; computational resources are provided by the Advanced Cyberinfrastructure Coordination Ecosystem (ACCESS-CI), Texas Advanced Computing Center, and the JetStream2 scientific cloud. Funding for open access charge: NIH. ELIXIR IS and Travel grants; EU Horizon Europe [HORIZON-INFRA-2021-EOSC-01-04, 101057388]; EU Horizon Europe under the Biodiversity, Circular Economy and Environment program (REA.B.3, BGE 101059492); German Federal Ministry of Education and Research, BMBF [031 A538A de.NBI-RBC]; Ministry of Science, Research and the Arts Baden-Württemberg (MWK) within the framework of LIBIS/de.NBI Freiburg. Galaxy Australia is supported by the Australian BioCommons which is funded through Australian Government NCRIS investments from Bioplatforms Australia and the Australian Research Data Commons, as well as investment from the Queensland Government RICF program
Assessment of team training in management of adverse acute events occurring during cardiopulmonary bypass procedure: a pilot study based on an animal simulation model (Fouilloux, Team training in cardiac surgery)
Assessment of team training in management of adverse acute events occurring during cardiopulmonary bypass procedure: a pilot study based on an animal simulation model (Fouilloux, Team training in cardiac surgery)
Successful cardiac surgery is highly dependent upon effective and efficient teamwork. Practical training and development will further enhance the team ability to react to a series of low-frequency occurring adverse events during cardiopulmonary bypass (CPB). One of our specialized educational programs focuses on training the whole team. This training is based on an original animal simulation model. The objective of this pilot study was to assess our method of training and learning in an attempt to optimize and improve team management and functioning. Methods: Four members of the same cardiac surgery team joined our program. They performed a common procedure, with a cardiopulmonary bypass (CPB) circuit set up to produce several adverse incidents. Events management was ana¬lyzed and debriefed in technical and non-technical perspectives. Results: Management of the adverse events was significantly improved. Discussion and debriefing time was fundamental in identifying the most appropriate management for each event. Rescue procedures were assimilated and team training was found to be effective, with the time reduced by up to 50% for 3 events and by up to 70% for air embolism. Conclusion: Our pilot program is an innovative, low-cost tool for the improvement of the management of adverse events occurring during CPB. It includes the different components of surgical education and training. Such an educational tool might be relevant for training. To confirm those encouraging results, it should be assessed in a larger surgical team panel. Further investigations are required for assessing efficiency in real conditions
Analysis of a 5-parent half diallel in dried pea (Pisum sativum L). I. Seed yield heterosis
Values of heterosis for seed yield and related traits have been calculated on F1 hybrids of dried pea (Pisum sativum L), obtained in a 5-parent half diallel cross. Lines used as parents represented a good sample of the genetic variability found in Northern Europe cultivars. The experiment was performed in microplots under competitive conditions (density: 100 pl/m2). Seed yield showed highly significant heterosis: 40% over the mid parent and 20% over the high parent respectively. Both general and specific combining ability were important. This study also concluded that heterosis was mainly expressed on branches. Heterosis for yield components was significant only for the number of pods/plant and the number of sseds/pod on the branches, but not for the number of seeds/pod on the whole plant or for dry weight/seed.Analyse d'un demi-diallèle à 5 parents chez le pois. I. Hétérosis du rendement en grains. Les valeurs d'hétérosis du rendement en grains et de caractères liés au rendement ont été calculées chez des hybrides F1 de pois (Pisum sativum L), obtenus dans un croisement demi-diallèle à 5 parents. Les lignées utilisées comme parents représentaient un bon échantillon de la variabilité génétique des cultivars du Nord de l'Europe. L'expérimentation a été effectuée en micro-parcelles, en conditions de compétition (densité : 100 pl/m2). Le rendement en grains a montré un hétérosis significatif : respectivement 40% par rapport au parent moyen et 20% par rapport au meilleur des 2 parents. Les aptitudes générale et spécifique à la combinaison étaient importantes. Cette étude a souligné le fait que le phénomène d'hétérosis s'exprimait principalement au niveau des ramifications. L'hétérosis pour les composantes du rendement était significatif seulement pour le nombre de gousses par plante et le nombre de graines par gousse sur les ramifications mais ne l'était pas pour le nombre de graines par gousse au niveau de la plante entière ni pour le poids sec du grain
Analysis of a 5-parent half diallel in dried pea (Pisum sativum L). I. Seed yield heterosis
Values of heterosis for seed yield and related traits have been calculated on F1 hybrids of dried pea (Pisum sativum L), obtained in a 5-parent half diallel cross. Lines used as parents represented a good sample of the genetic variability found in Northern Europe cultivars. The experiment was performed in microplots under competitive conditions (density: 100 pl/m2). Seed yield showed highly significant heterosis: 40% over the mid parent and 20% over the high parent respectively. Both general and specific combining ability were important. This study also concluded that heterosis was mainly expressed on branches. Heterosis for yield components was significant only for the number of pods/plant and the number of sseds/pod on the branches, but not for the number of seeds/pod on the whole plant or for dry weight/seed.Analyse d'un demi-diallèle à 5 parents chez le pois. I. Hétérosis du rendement en grains. Les valeurs d'hétérosis du rendement en grains et de caractères liés au rendement ont été calculées chez des hybrides F1 de pois (Pisum sativum L), obtenus dans un croisement demi-diallèle à 5 parents. Les lignées utilisées comme parents représentaient un bon échantillon de la variabilité génétique des cultivars du Nord de l'Europe. L'expérimentation a été effectuée en micro-parcelles, en conditions de compétition (densité : 100 pl/m2). Le rendement en grains a montré un hétérosis significatif : respectivement 40% par rapport au parent moyen et 20% par rapport au meilleur des 2 parents. Les aptitudes générale et spécifique à la combinaison étaient importantes. Cette étude a souligné le fait que le phénomène d'hétérosis s'exprimait principalement au niveau des ramifications. L'hétérosis pour les composantes du rendement était significatif seulement pour le nombre de gousses par plante et le nombre de graines par gousse sur les ramifications mais ne l'était pas pour le nombre de graines par gousse au niveau de la plante entière ni pour le poids sec du grain
Development of sequence-tagged-site (STS) PCR markers and study of simple-sequence-repeats (SSR) for variety testing in oilseed rape (Brassica Napus).
International audienc
Detection of pulmonary and coronary artery anomalies in tetralogy of ă Fallot using non-ECG-gated CT angiography
International audienceObjectives: To evaluate the use of non-ECG-gated computed tomography ă (CT) angiography to describe pulmonary and coronary defects in patients ă with tetralogy of Fallot (TOF). ă Patients and methods: This retrospective study was carried out on TOF ă patients having undergone pre-operative non-ECG-gated CT angiography ă between February 2007 and September 2012. The following clinical ă parameters were recorded: mean age at CT angiography, sex, the existence ă of genetic disease and the need to sedate the patient prior to CT ă angiography. CT data were analyzed retrospectively to determine the ă site(s) of pulmonary stenosis (infundibular, valvular or arterial), the ă size of pulmonary arteries and the presence of anomalous coronary artery ă courses. CT findings were then compared to the anatomy observed during ă surgery. ă Results: Thirty-five patients were included in the study. The mean age ă was 4.30 +/- 1.91 months (boys/girls = 17/18). Two patients had ă associated chromosome disorders (one 22q11 microdeletion and one CHARGE ă syndrome). Sixteen patients (45.71%) were sedated prior to CT. ă Pulmonary artery assessment revealed 24 patients (68.57%) with ă infundibular stenosis, 5 (17.5%) with infundibular and/or valvular ă stenosis, and 6 (21%) with anomalous pulmonary arteries. CT angiography ă also evidenced anomalous coronary arteries in 8 patients (22.85%). ă Conclusion: Due to its reduced scanning time and high spatial ă resolution, non-ECG-gated CT angiography is a non-invasive imaging ă modality that provides accurate information on pulmonary and coronary ă artery anatomy in patients with TOF. (C) 2016 Editions francaises de ă radiologie. Published by Elsevier Masson SAS. All rights reserved