Non-linear analysis of geomagnetic time series from Etna volcano

International audienceAn intensive nonlinear analysis of geomagnetic time series from the magnetic network on Etna volcano was carried out to investigate the dynamical behavior of magnetic anomalies in volcanic areas. The short-term predictability of the geomagnetic time series was evaluated to establish a possible low-dimensional deterministic dynamics. We estimated the predictive ability of both a nonlinear forecasting technique and a global autoregressive model by comparing the prediction errors. Our findings highlight that volcanomagnetic signals are the result of complex processes that cannot easily be predicted. There is slight evidence based on nonlinear predictions, that the geomagnetic time series are to be governed by many variables, whose time evolution could be better regarded as arising from complex high dimensional processes

Multicultural Academic Interest Group: Promoting Multicultural Research, Education & Services

Eliminating racial/ethnic disparities in access and quality of mental care has emerged as a national priority as highlighted in the 2001 Surgeon General’s report, the President’s New Freedom Commission on Mental Health, and Healthy People 2000 and 2010. The National Institutes of Health (NIH) ranks this issue third among its top five priorities

Magnetic field resistant quantum interferences in bismuth nanowires based Josephson junctions

We investigate proximity induced superconductivity in micrometer-long bismuth nanowires con- nected to superconducting electrodes with a high critical field. At low temperature we measure a supercurrent that persists in magnetic fields as high as the critical field of the electrodes (above 11 T). The critical current is also strongly modulated by the magnetic field. In certain samples we find regular, rapid SQUID-like periodic oscillations occurring up to high fields. Other samples ex- hibit less periodic but full modulations of the critical current on Tesla field scales, with field-caused extinctions of the supercurrent. These findings indicate the existence of low dimensionally, phase coherent, interfering conducting regions through the samples, with a subtle interplay between orbital and spin contributions. We relate these surprising results to the electronic properties of the surface states of bismuth, strong Rashba spin-orbit coupling, large effective g factors, and their effect on the induced superconducting correlations.Comment: 5 page

Comparison of ELISA and HPLC-MS methods for the determination of exenatide in biological and biotechnology-based formulation matrices

The development of biotechnology-based active pharmaceutical ingredients, such as GLP-1 analogs, brought changes in type 2 diabetes treatment options. For better therapeutic efficiency, these active pharmaceutical ingredients require appropriate administration, without the development of adverse effects or toxicity. Therefore, it is required to develop several quantification methods for GLP-1 analogs products, in order to achieve the therapeutic goals, among which ELISA and HPLC arise. These methods are developed, optimized and validated in order to determine GLP-1 analogs, not only in final formulation of the active pharmaceutical ingredient, but also during preclinical and clinical trials assessment. This review highlights the role of ELISA and HPLC methods that have been used during the assessment for GLP-1 analogs, especially for exenatide

A 26-Year Experience in Chorionic Villus Sampling Prenatal Genetic Diagnosis

Abstract: This report describes the trends of chorionic villus sampling (CVS) referred for prenatal genetic diagnosis in the past two and a half decades in a Portuguese Center. Our cohort of 491 CVS was mostly performed by the transcervical method at the 12th gestational week. Data collected within the framework of this study relate to the following: sampling method, referral reason versus abnormality and incidence of procedure-related pregnancy loss, that declined to about 0.5% over the last 15 years. The year 2000 represented a change in referral reasons for chorionic tissue collection, shifting from almost exclusively for cytogenetic testing to an increasing number of molecular tests for monogenic disorders. Herein, success rates as well as cytogenetic and/or molecular DNA results are presented. These latter include not only tests for several monogenic disorders, but also aneuploidy and maternal cell contamination screening. This retrospective analysis reiterates that CVS is a safe and reliable first trimester technique for prenatal diagnosis in high genetic risk pregnancies

Non-linear analysis of geomagnetic time series from Etna volcano

An intensive nonlinear analysis of geomagnetic time series from the magnetic network on Etna volcano was carried out to investigate the dynamical behavior of magnetic anomalies in volcanic areas. The short-term predictability of the geomagnetic time series was evaluated to establish a possible low-dimensional deterministic dynamics. We estimated the predictive ability of both a nonlinear forecasting technique and a global autoregressive model by comparing the prediction errors. Our findings highlight that volcanomagnetic signals are the result of complex processes that cannot easily be predicted. There is slight evidence based on nonlinear predictions, that the geomagnetic time series are to be governed by many variables, whose time evolution could be better regarded as arising from complex high dimensional processes

Lifetime Alcohol Abuse Prevalence: Role of Childhood and Adult Religion

Findings presented regarding childhood and adult religiosity/spirituality as protective factors against Lifetime Alcohol Abuse

Distal and Proximal Religiosity as Protective Factors for Adolescent and Emerging Adult Alcohol Use

Data from emerging adults (ages 18-29, N = 900) in the National Comorbidity Survey Replication Study was used to examine the influence of childhood and emerging adult religiosity and religious-based decision-making, and childhood adversity, on alcohol use. Childhood religiosity was protective against early alcohol use and progression to later abuse or dependence, but did not significantly offset the influence of childhood adversity on early patterns of heavy drinking in adjusted logistic regression models. Religiosity in emerging adulthood was negatively associated with alcohol use disorders. Protective associations for religiosity varied by gender, ethnicity and childhood adversity histories. Higher religiosity may be protective against early onset alcohol use and later development of alcohol problems, thus, should be considered in prevention programming for youth, particularly in faith-based settings. Mental health providers should allow for integration of clients\u27 religiosity and spirituality beliefs and practices in treatment settings if clients indicate such interest

Coevolutionary dynamics shape the structure of bacteria‐phage infection networks

Coevolution—reciprocal evolutionary change among interacting species driven by natural selection—is thought to be an important force in shaping biodiversity. This ongoing process takes place within tangled networks of species interactions. In microbial communities, evolutionary change between hosts and parasites occurs at the same time scale as ecological change. Yet, we still lack experimental evidence of the role of coevolution in driving changes in the structure of such species interaction networks. Filling this gap is important because network structure influences community persistence through indirect effects. Here, we quantified experimentally to what extent coevolutionary dynamics lead to contrasting patterns in the architecture of bacteria–phage infection networks. Specifically, we look at the tendency of these networks to be organized in a nested pattern by which the more specialist phages tend to infect only a proper subset of those bacteria infected by the most generalist phages. We found that interactions between coevolving bacteria and phages become less nested over time under fluctuating dynamics, and more nested under arms race dynamics. Moreover, when coevolution results in high average infectivity, phages and bacteria differ more from each other over time under arms race dynamics than under fluctuating dynamics. The tradeoff between the fitness benefits of evolving resistance/infectivity traits and the costs of maintaining them might explain these differences in network structure. Our study shows that the interaction pattern between bacteria and phages at the community level depends on the way coevolution unfolds.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/149309/1/evo13731_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/149309/2/evo13731.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/149309/3/evo13731-sup-0001-TableS1.pd

Efectos del destete precoz sobre el ternero

En el Campo Experimental de la Facultad de Agronomía de la Universidad Nacional de La Pampa, se llevó a cabo entre julio de 1994 y marzo de 1995 un ensayo de destete precoz con temeros hijos de vaquillonas. El objetivo de este trabajo, fue determinar el efecto de la lactancia reducida en los temeros (ganancia de peso y el peso al destete ajustado a los 210 días). Se contrastaron dos fechas de destete (60 y 210 días) en lotes que fueron agrupados por fecha de parto y sexo del ternero. Se utilizaron treinta temeros machos y hembras cruzas que tenían un setenta y cinco por ciento (75%) de sangre Aberdeen Angus y un veinticinco por ciento (25%) de Jersey. No se encontraron diferencias en el peso de destete ajustado, aunque si se encontraron diferencias significativas en ganancias de pesos parciales.Director: lng. Agr. Gustavo D. Fernández, y Codirector: Ing. Agr. Abel E. Zuccari (Cátedra de Zootecnia 1)