1,388 research outputs found
Computer considerations for real time simulation of a generalized rotor model
Scaled equations were developed to meet requirements for real time computer simulation of the rotor system research aircraft. These equations form the basis for consideration of both digital and hybrid mechanization for real time simulation. For all digital simulation estimates of the required speed in terms of equivalent operations per second are developed based on the complexity of the equations and the required intergration frame rates. For both conventional hybrid simulation and hybrid simulation using time-shared analog elements the amount of required equipment is estimated along with a consideration of the dynamic errors. Conventional hybrid mechanization using analog simulation of those rotor equations which involve rotor-spin frequencies (this consititutes the bulk of the equations) requires too much analog equipment. Hybrid simulation using time-sharing techniques for the analog elements appears possible with a reasonable amount of analog equipment. All-digital simulation with affordable general-purpose computers is not possible because of speed limitations, but specially configured digital computers do have the required speed and consitute the recommended approach
Computer mechanization of six-degree of freedom flight equations
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/69091/2/10.1177_003754976801100407.pd
The Amplification and Characterization of Mycobacteriophages MyPhage and SolarFlare
Bacteriophages are viruses that infect and replicate in bacteria and are being researched for medical applications. MyPhage is a Mycobacteriophage discovered in Anaconda, Montana in May of 2009. The student found the phage in soil from a potted plant. The background of SolarFlare is unknown.https://digitalcommons.mtech.edu/urp_aug_2018/1003/thumbnail.jp
An app-enhanced cognitive fitness training program for athletes: The rationale and validation protocol
An app-enhanced cognitive fitness training program for athletes: The rationale and validation protocol
Heterogeneity
This entry discusses heterogeneity in the context of ecological landscapes and how the heterogeneity impacts the resilience of the system. Heterogeneity is closely linked to the scale of measurement, both spatially and temporally. We will walk through a simple example that highlights how the scale of observation can impact the heterogeneity of the system. The differences between functional and measured heterogeneity will also be explained. Finally, heterogeneity will be discussed in the context of its utility to management and how it can be used to understand the resilience of agro-ecosystems. Overview - What Will You Learn In This Lesson?
This lesson discusses what heterogeneity is and how it relates to understanding and interpreting natural phenomena. Objectives
This lesson covers the concept of heterogeneity. At the end of this module you should be able to: Define heterogeneity in the context of environmental management Explain the relationship between heterogeneity and ecological resilience Differentiate between functional and measured heterogeneity in ecology Understand the importance and usefulness of heterogeneity in resource management
Modules Lesson home Overview and Objectives Introduction - What Is Heterogeneity? Measures of Heterogeneity Heterogeneity in Management - How Does This Concept Impact Real-World Management? Example - Heterogeneity of Zoning in Cities Summary - What Did We Learn? Quiz Questions References and Further Reading Glossar
Wildlife Damage to Seedlings in Reforested in Hardwood Sites in Mississippi
Herbivory assessments were conducted on seven reforested sites that were less than one year old in the following Mississippi counties: Bolivar, Leflore, and Attala. At each site, 100ft. x 100 ft. plots were established and randomly selected seedlings were marked and measured to determine seedling species, height, condition, survival, and type and extent of animal feeding sign. Surveys were conducted in March/April, May, and August 2004. Herbivory rates were highest during May with approximately 47% of seedlings showing signs of herbivory. In March/ April and August, the percentage of seedlings exhibiting signs of herbivory was 37% and 30%, respectively. Foraging by white-tailed deer (Odocoileus virginianus) was recorded on \u3e 90% of the damaged seedlings during each survey. Tree mortality for all study sites and tree species was negligible, with the highest amount (7%) recorded during August, despite the recorded rates of herbivory by white-tailed deer. Herbivory by rabbits (Sylvilagus spp.) and rodents occurred on approximately 6% of the seedlings throughout the 2004 growing season
Genetic models of apoptosis-induced proliferation decipher activation of JNK and identify a requirement of EGFR signaling for tissue regenerative responses in Drosophila
Recent work in several model organisms has revealed that apoptotic cells are able to stimulate neighboring surviving cells to undergo additional proliferation, a phenomenon termed apoptosis-induced proliferation. This process depends critically on apoptotic caspases such as Dronc, the Caspase-9 ortholog in Drosophila, and may have important implications for tumorigenesis. While it is known that Dronc can induce the activity of Jun N-terminal kinase (JNK) for apoptosis-induced proliferation, the mechanistic details of this activation are largely unknown. It is also controversial if JNK activity occurs in dying or in surviving cells. Signaling molecules of the Wnt and BMP families have been implicated in apoptosis-induced proliferation, but it is unclear if they are the only ones. To address these questions, we have developed an efficient assay for screening and identification of genes that regulate or mediate apoptosis-induced proliferation. We have identified a subset of genes acting upstream of JNK activity including Rho1. We also demonstrate that JNK activation occurs both in apoptotic cells as well as in neighboring surviving cells. In a genetic screen, we identified signaling by the EGFR pathway as important for apoptosis-induced proliferation acting downstream of JNK signaling. These data underscore the importance of genetic screening and promise an improved understanding of the mechanisms of apoptosis-induced proliferation
Rapid, diffusional shuttling of poly(A) RNA between nuclear speckles and the nucleoplasm
Speckles are nuclear bodies that contain pre-mRNA splicing factors and polyadenylated RNA. Because nuclear poly(A) RNA consists of both mRNA transcripts and nucleus-restricted RNAs, we tested whether poly(A) RNA in speckles is dynamic or rather an immobile, perhaps structural, component. Fluorescein-labeled oligo(dT) was introduced into HeLa cells stably expressing a red fluorescent protein chimera of the splicing factor SC35 and allowed to hybridize. Fluorescence correlation spectroscopy (FCS) showed that the mobility of the tagged poly(A) RNA was virtually identical in both speckles and at random nucleoplasmic sites. This same result was observed in photoactivation-tracking studies in which caged fluorescein-labeled oligo(dT) was used as hybridization probe, and the rate of movement away from either a speckle or nucleoplasmic site was monitored using digital imaging microscopy after photoactivation. Furthermore, the tagged poly(A) RNA was observed to rapidly distribute throughout the entire nucleoplasm and other speckles, regardless of whether the tracking observations were initiated in a speckle or the nucleoplasm. Finally, in both FCS and photoactivation-tracking studies, a temperature reduction from 37 to 22°C had no discernible effect on the behavior of poly(A) RNA in either speckles or the nucleoplasm, strongly suggesting that its movement in and out of speckles does not require metabolic energy. © 2006 by The American Society for Cell Biology
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