4,361 research outputs found
Floquet bound states around defects and adatoms in graphene
Recent studies have focused on laser-induced gaps in graphene which have been
shown to have a topological origin, thereby hosting robust states at the sample
edges. While the focus has remained mainly on these topological chiral edge
states, the Floquet bound states around defects lack a detailed study. In this
paper we present such a study covering large defects of different shape and
also vacancy-like defects and adatoms at the dynamical gap at
( being the photon energy). Our results, based on analytical
calculations as well as numerics for full tight-binding models, show that the
bound states are chiral and appear in a number which grows with the defect
size. Furthermore, while the bound states exist regardless the type of the
defect's edge termination (zigzag, armchair, mixed), the spectrum is strongly
dependent on it. In the case of top adatoms, the bound states quasi-energies
depend on the adatoms energy. The appearance of such bound states might open
the door to the presence of topological effects on the bulk transport
properties of dirty graphene.Comment: 16 pages, 14 figure
Human biological monitoring of industrial chemicals series. 4. Inorganic lead. Industrial health and safety. EUR 6982 EN
Spin interference and Fano effect in electron transport through a mesoscopic ring side-coupled with a quantum dot
We investigate the electron transport through a mesoscopic ring side-coupled
with a quantum dot(QD) in the presence of Rashba spin-orbit(SO) interaction. It
is shown that both the Fano resonance and the spin interference effects play
important roles in the electron transport properties. As the QD level is around
the Fermi energy, the total conductance shows typical Fano resonance line
shape. By applying an electrical gate voltage to the QD, the total transmission
through the system can be strongly modulated. By threading the mesoscopic ring
with a magnetic flux, the time-reversal symmetry of the system is broken, and a
spin polarized current can be obtained even though the incident current is
unpolarized.Comment: 5 pages, 5 figure
A search in the COS-B data base for correlated time variability in regions containing objects of interest
As is well known, association of the gamma-ray sources with celestial objects is, in general, difficult on a pure positional basis, while correlated time variability could obviously provide such proof. This technique can be employed on regions of the gamma-ray sky containing interesting objects of known variability at some wavelength even in the absence of a recognized gamma-ray excess with the aim to extract a weak but predictable signal from the surrounding noise. This technique is applied here on a longer variability time scale, generally of the order of days. Photons coming from the sky regions centered on the various celestial objects considered were selected with energies 100 MeV and with arrival directions within an energy-dependent area of radius of approx 6 deg at 100 MeV. In order to construct a time profile of such photons, their arrival times were grouped in bins of dimensions defined by the available photons number and by the value of the period searched for
IL2 treatment for cancer: from biology to gene therapy.
In this review we shall discuss the biological rationale and the clinical findings obtained using Interleukin 2 (IL2)-based immunotherapy in the management of cancer patients. Objective and long-lived clinical responses have been documented in a proportion of cases, particularly renal cell carcinoma, melanoma and acute myeloid leukaemia. Though encouraging, the clinical use of IL2 has so far been limited by toxicity, as well as by the heterogeneous and unpredictable responses and by the lack of specific anti-tumour effect. These considerations have led to the belief that more sophisticated technologies aimed at introducing the IL2 gene into the neoplastic cells may potentially overcome some of the limitations coupled to the in vivo infusion of high doses of IL2. The data accumulated in animal models and, more recently, also with human tumour cells indicate that the IL2 gene may be successfully inserted into neoplastic cells. The constitutive secretion of IL2 by the tumour cells leads to a reduced or abrogated tumorigenicity in several different tumour models. The evidence that in some experimental tumours the transduction of the IL2 gene into the neoplastic cells may elicit a specific cytotoxic response and confer anti-tumour memory, suggests that vaccination protocols based on this innovative strategy may represent a potential new tool in the management of cancer patients
Floquet interface states in illuminated three-dimensional topological insulators
Recent experiments showed that the surface of a three dimensional topological
insulator develops gaps in the Floquet-Bloch band spectrum when illuminated
with a circularly polarized laser. These Floquet-Bloch bands are characterized
by non-trivial Chern numbers which only depend on the helicity of the
polarization of the radiation field. Here we propose a setup consisting of a
pair of counter-rotating lasers, and show that one-dimensional chiral states
emerge at the interface between the two lasers. These interface states turn out
to be spin-polarized and may trigger interesting applications in the field of
optoelectronics and spintronics.Comment: 5 pages with 3 figures + supplemental materia
Topological and flat bands states induced by hybridized interactions in one-dimensional photonic lattices
We report on a study of a one-dimensional linear photonic lattice hosting,
simultaneously, fundamental and dipolar modes at every site. We show how,
thanks to the interaction between the different orbital modes, this minimal
model exhibits rich transport and topological properties. By varying the
detuning coefficient we find a regime where bands become flatter (with reduced
transport) and, a second regime, where both bands connect on at a gap-closing
transition (with enhanced transport). We detect an asymmetric transport due to
the asymmetric inter-mode coupling and a linear energy exchange mechanism
between modes. Further analysis show that the bands have a topological
transition with a non-trivial Zak phase which leads to the appeareance of edge
states in a finite system. Finally, for zero detuning, we found a symmetric
condition for coupling constants, where the linear spectrum becomes completely
flat, with states fully localized in space occupying only two lattice sites.Comment: 8 pages, 5 figure
Imaging of biliary involvement in sarcoidosis: Computed tomography, magnetic resonance cholangiopancreatography, and gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging findings
Sarcoidosis is a multisystem disease usually affecting the chest, hilar lymph nodes, and lungs, but can potentially involve any organ; therefore, its clinical presentation may vary. Hepato-biliary involvement is rare, and typically asymptomatic; however, it can lead to cirrhosis, and may require liver transplantation. In this report, we present a rare case of a patient affected by sarcoidosis with hepatobiliary involvement. He presented to our hospital complaining of dyspnea triggered by moderate efforts and oppressive thoracic discomfort. Chest X-ray showed multiple bilateral nodular opacities and enlargement of both hilar regions, confirmed by a subsequent total-body computed tomography scan and positron emission tomography, which also revealed cardiac, splenic, and hepatic involvement. Liver function was studied via gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging, and magnetic resonance cholangiopancreatography (MRCP) was also performed. The diagnosis of sarcoidosis was finally achieved via liver biopsy, revealing non-necrotizing granulomas in the periportal space. The patient was treated with prednisone per os, with regression of all lesions at all levels. Although other cases of biliary sarcoidosis have been described, this report provides a complete image set of Gd-EOB-DTPA-enhanced magnetic resonance and MRCP images that is lacking in the English literature, and which may be useful for diagnosis
Multiterminal conductance of a floquet topological insulator
We report on simulations of the dc conductance and quantum Hall response of a Floquet topological insulator using Floquet scattering theory. Our results reveal that laser-induced edge states lead to quantum Hall plateaus once imperfect matching with the nonilluminated leads is lessened. The magnitude of the Hall plateaus, however, is not directly related to the number and chirality of all the edge states at a given energy, as usual. Instead, the plateaus are dominated by those edge states adding to the time-averaged density of states. Therefore, the dc quantum Hall conductance of a Floquet topological insulator is not directly linked to topological invariants of the full Floquet bands.publishedVersionFil: Foa Torres, Luis Eduardo Francisco. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Física Enrique Gaviola; Argentina.Fil: Foa Torres, Luis Eduardo Francisco. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía y Física; Argentina.Fil: Pérez Piskunow, Pablo Matías. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Física Enrique Gaviola; Argentina.Fil: Pérez Piskunow, Pablo Matías. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía y Física; Argentina.Fil: Balseiro, Carlos A. Comisión Nacional de Energía Atómica. Centro Atómico Bariloche; Argentina.Fil: Balseiro, Carlos A. Comisión Nacional de Energía Atómica. Instituto Balseiro; Argentina.Fil: Balseiro, Carlos A. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.Fil: Usaj, Gonzalo. Comisión Nacional de Energía Atómica. Centro Atómico Bariloche; Argentina.Fil: Usaj, Gonzalo. Comisión Nacional de Energía Atómica. Instituto Balseiro; Argentina.Fil: Usaj, Gonzalo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.Física de los Materiales Condensado
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