92 research outputs found
Dynamic simulations in SixTrack
The DYNK module allows element settings in SixTrack to be changed on a
turn-by-turn basis. This document contains a technical description of the DYNK
module in SixTrack. It is mainly intended for a developer or advanced user who
wants to modify the DYNK module, for example by adding more functions that can
be used to calculate new element settings, or to add support for new elements
that can be used with DYNK.Comment: Submission to CERN yellow report / conference proceeding, the 2015
collimation tracking code worksho
90 m optics commissioning
http://accelconf.web.cern.ch/AccelConf/IPAC2011/papers/tupz001.pdfInternational audienceSpecial β∗ = 90 m optics have been developed for the two very high luminosity insertions of the LHC [1] [2], as a rst step to allow for very low angle precision measure- ments of the proton-proton collisions in the LHC. These optics were developed to be compatible with the stan- dard LHC injection and ramp optics. The target value of β∗ = 90 m is reached by an un-squeeze from the injection β∗ = 11 m. We report about the implementation of this op- tics and the rst experience gained in commissioning with beam during two machine studies
Halo and tail simulations with applications to the CLIC drive beam
We report about generic halo and tail simulations and estimates. Previous studies weremainly focused on very high energies as relevant for the beam delivery systems of linear colliders. We have now studied, applied and extended these simulations to lower energies as relevant for the CLIC drive beam
A Large Hadron Electron Collider at CERN
This document provides a brief overview of the recently published report on
the design of the Large Hadron Electron Collider (LHeC), which comprises its
physics programme, accelerator physics, technology and main detector concepts.
The LHeC exploits and develops challenging, though principally existing,
accelerator and detector technologies. This summary is complemented by brief
illustrations of some of the highlights of the physics programme, which relies
on a vastly extended kinematic range, luminosity and unprecedented precision in
deep inelastic scattering. Illustrations are provided regarding high precision
QCD, new physics (Higgs, SUSY) and electron-ion physics. The LHeC is designed
to run synchronously with the LHC in the twenties and to achieve an integrated
luminosity of O(100) fb. It will become the cleanest high resolution
microscope of mankind and will substantially extend as well as complement the
investigation of the physics of the TeV energy scale, which has been enabled by
the LHC
Study of the plant COPII vesicle coat subunits by functional complementation of yeast Saccharomyces cerevisiae mutants
The formation and budding of endoplasmic reticulum ER-derived vesicles depends on the COPII coat protein complex that was first identified in yeast Saccharomyces cerevisiae. The ER-associated Sec12 and the Sar1 GTPase initiate the COPII coat formation by recruiting the Sec23-Sec24 heterodimer following the subsequent recruitment of the Sec13-Sec31 heterotetramer. In yeast, there is usually one gene encoding each COPII protein and these proteins are essential for yeast viability, whereas the plant genome encodes multiple isoforms of all COPII subunits. Here, we used a systematic yeast complementation assay to assess the functionality of Arabidopsis thaliana COPII proteins. In this study, the different plant COPII subunits were expressed in their corresponding temperature-sensitive yeast mutant strain to complement their thermosensitivity and secretion phenotypes. Secretion was assessed using two different yeast cargos: the soluble alpha-factor pheromone and the membranous v-SNARE (vesicle-soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor) Snc1 involved in the fusion of the secretory vesicles with the plasma membrane. This complementation study allowed the identification of functional A. thaliana COPII proteins for the Sec12, Sar1, Sec24 and Sec13 subunits that could represent an active COPII complex in plant cells. Moreover, we found that AtSec12 and AtSec23 were co-immunoprecipitated with AtSar1 in total cell extract of 15 day-old seedlings of A. thaliana. This demonstrates that AtSar1, AtSec12 and AtSec23 can form a protein complex that might represent an active COPII complex in plant cells
Machine layout and performance
The Large Hadron Collider (LHC) is one of the largest scientific instruments ever built. Since opening up a new
energy frontier for exploration in 2010, it has gathered a global user community of about 7,000 scientists working
in fundamental particle physics and the physics of hadronic matter at extreme temperature and density. To sustain
and extend its discovery potential, the LHC will need a major upgrade in the 2020s. This will increase its luminosity
(rate of collisions) by a factor of five beyond the original design value and the integrated luminosity (total
collisions created) by a factor ten. The LHC is already a highly complex and exquisitely optimised machine so this
upgrade must be carefully conceived and will require about ten years to implement. The new configuration, known
as High Luminosity LHC (HL-LHC), will rely on a number of key innovations that push accelerator technology
beyond its present limits. Among these are cutting-edge 11-12 tesla superconducting magnets, compact superconducting
cavities for beam rotation with ultra-precise phase control, new technology and physical processes
for beam collimation and 300 metre-long high-power superconducting links with negligible energy dissipation.
The present document describes the technologies and components that will be used to realise the project and is
intended to serve as the basis for the detailed engineering design of HL-LHC
Policing, crime and ‘big data’; towards a critique of the moral economy of stochastic governance
Process management in hospitals: an empirically grounded maturity model
In order to improve transparency and stabilise health care costs, several countries have decided to reform their healthcare system on the basis of diagnosis-related groups (DRG). DRGs are not only used for classifying medical treatments, but also for case-based reimbursement, hence induce active competition among hospitals, forcing them to become more efficient and effective. In consequence, hospitals are investing considerably in process orientation and management. However, to date there is neither a consensus on what capabilities hospitals need to acquire for becoming process-oriented, nor a general agreement on the sequence of development stages they have to traverse. To this end, this study proposes an empirically grounded conceptualisation of process management capabilities and presents a staged capability maturity model algorithmically derived on the basis of empirical data from 129 acute somatic hospitals in Switzerland. The five capability maturity levels start with 'encouragement of process orientation' (level 1), 'case-by-case handling' (level 2), and 'defined processes' (level 3). Ultimately, hospitals can reach the levels 'occasional corrective action' (level 4) and 'closed loop improvement' (level 5). The empirically derived model reveals why existing, generic capability maturity models for process management are not applicable in the hospitals context: their comparatively high complexity on the one hand and their strong focus on topics like an adequate IT integration and process automation on the other make them inadequate for solving the problems felt in the hospital sector, which are primarily of cultural and structural nature. We deem the proposed capability maturity model capable to overcome these shortcomings
A Large Hadron Electron Collider at CERN
The physics programme and the design are described of a new collider for particle and nuclear physics, the Large Hadron Electron Collider (LHeC), in which a newly built electron beam of 60 GeV, to possibly 140 GeV, energy collides with the intense hadron beams of the LHC. Compared to the first ep collider, HERA, the kinematic range covered is extended by a factor of twenty in the negative four-momentum squared, Q2, and in the inverse Bjorken x, while with the design luminosity of 1033 cm-2 s-1 the LHeC is projected to exceed the integrated HERA luminosity by two orders of magnitude. The physics programme is devoted to an exploration of the energy frontier, complementing the LHC and its discovery potential for physics beyond the Standard Model with high precision deep inelastic scattering measurements. These are designed to investigate a variety of fundamental questions in strong and electroweak interactions. The LHeC thus continues the path of deep inelastic scattering (DIS) into unknown areas of physics and kinematics. The physics programme also includes electron-deuteron and electron-ion scattering in a (Q21/x) range extended by four orders of magnitude as compared to previous lepton-nucleus DIS experiments for novel investigations of neutron's and nuclear structure, the initial conditions of Quark-Gluon Plasma formation and further quantum chromodynamic phenomena. The LHeC may be realised either as a ring-ring or as a linac-ring collider. Optics and beam dynamics studies are presented for both versions, along with technical design considerations on the interaction region, magnets including new dipole prototypes, cryogenics, RF, and further components. A design study is also presented of a detector suitable to perform high precision DIS measurements in a wide range of acceptance using state-of-the art detector technology, which is modular and of limited size enabling its fast installation. The detector includes tagging devices for electron, photon, proton and neutron detection near to the beam pipe. Civil engineering and installation studies are presented for the accelerator and the detector. The LHeC can be built within a decade and thus be operated while the LHC runs in its high-luminosity phase. It so represents a major opportunity for progress in particle physics exploiting the investment made in the LHC
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