2,512 research outputs found
Evidence of a structural anomaly at 14 K in polymerised CsC60
We report the results of a high-resolution synchrotron X-ray powder
diffraction study of polymerised CsC in the temperature range 4 to 40 K.
Its crystal structure is monoclinic (space group I2/m), isostructural with
RbC. Below 14 K, a spontaneous thermal contraction is observed along
both the polymer chain axis, and the interchain separation along [111],
. This structural anomaly could trigger the occurrence of the spin-singlet
ground state, observed by NMR at the same temperature.Comment: 8 pages, 5 figures, submitte
Complete genome sequences of three novel Pseudomonas fluorescens SBW25 bacteriophages, Noxifer, Phabio, and Skulduggery
Three novel bacteriophages, two of which are jumbophages, were isolated from compost in Auckland, New Zealand. Noxifer, Phabio, and Skulduggery are double-stranded DNA (dsDNA) phages with genome sizes of 278,136 bp (Noxifer), 309,157 bp (Phabio), and 62,978 bp (Skulduggery)
Beyond the catwalk: Fashion public relations and social media in Australia
This study explores social media use in public relations in the Australian fashion industry, using ethnographic inquiry and semi-structured interviews. There has been limited research into fashion public relations (fashion PR), despite the economic and cultural significance of the fashion industry. The findings suggest social media is transforming fashion PR, but its adoption is uneven, with overlaps in marketing and public relations activity. Participants use social media to engage fashion publics, keep up-to-date with trends, monitor competitors and promote clients. Bloggers are increasingly influential. Participants perceive they must embrace social media, or risk getting left behind. The findings contribute to understanding diverse public relations practices and the ways public relations activity is changing in response to social media
“Parties, air-kissing and long boozy lunches”? Public relations in the Australian fashion industry
There has been limited research into fashion public relations. This study explores public relations in the Australian fashion industry using ethnographic research and semistructured interviews with six fashion public relations practitioners. The findings suggest fashion public relations does not easily fit into mainstream understandings of public relations. Rather, fashion public relations is assigned a low status due to its close association with marketing, promotion and publicity and popular representations of the fashion sector as glamorous and superficial. Despite this, participants perceived their work to be professional, where the dominant activities of media relations, celebrity endorsement, and relationship management form part of a carefully devised strategic plan to meet organisational and client objectives. The findings offer an alternative perspective on public relations by considering practitioner experiences in a niche industry field. The study provides new understandings of public relations and calls for a reconceptualisation of the field beyond the narrow remit of mainstream public relations definitions and professional associations
Exploring Molecular Simulations of a Plausible Prebiotic Reduced Phospholipid Using Hyperchem Software
How the first cells emerged from the primordial milieu is one of the great questions in science. Biomolecular emergence scenarios abound in the literature, but the lack of bioaccessible phosphate and molecular oxygen on the primordial Earth has posed formidable challenges for deducing emergence pathways. One idea gaining wide acceptance invokes delivery of the phosphide mineral schreibersite ((Fe,Ni)3P) to Earth via meteorite impacts ca. 4.2 billion years ago, whereupon they were corroded to reduced phosphorous oxyacids and phosphonates in primordial aquatic environments. We previously proposed that these reduced phosphorus forms could readily combine with putative geochemical species in shallow mineral-rich alkaline hydrothermal systems to form reduced phospholipid analogs of contemporary phosphate-based phospholipids (Fitch, N.W., K.L. Even, L.J. Leinen and M.O. Gaylor. 2016. Plausible prebiotic assembly of a primitive reduced phospholipid from meteoritic phosphorus on the primordial earth. Proceedings of the South Dakota Academy of. Science 95:176.). Lacking resources to empirically validate this idea, we explored “water box” simulations of the proposed phospholipid structure using the HyperChem software package. Simulation results showed the hydrophobic tails migrating away from water molecules, while hydrophilic heads migrated towards them, resulting in quasistacking behaviors consistent with those of known amphiphiles in water. Inspired by these results, we are now investigating more complex primordial simulation scenarios
Cross modal perception of body size in domestic dogs (Canis familiaris)
While the perception of size-related acoustic variation in animal vocalisations is well documented, little attention has been given to how this information might be integrated with corresponding visual information. Using a cross-modal design, we tested the ability of domestic dogs to match growls resynthesised to be typical of either a large or a small dog to size- matched models. Subjects looked at the size-matched model significantly more often and for a significantly longer duration than at the incorrect model, showing that they have the ability to relate information about body size from the acoustic domain to the appropriate visual category. Our study suggests that the perceptual and cognitive mechanisms at the basis of size assessment in mammals have a multisensory nature, and calls for further investigations of the multimodal processing of size information across animal species
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An ANGPTL4-ceramide-protein kinase Cζ axis mediates chronic glucocorticoid exposure-induced hepatic steatosis and hypertriglyceridemia in mice.
Chronic or excess glucocorticoid exposure causes lipid disorders such as hypertriglyceridemia and hepatic steatosis. Angptl4 (angiopoietin-like 4), a primary target gene of the glucocorticoid receptor in hepatocytes and adipocytes, is required for hypertriglyceridemia and hepatic steatosis induced by the synthetic glucocorticoid dexamethasone. Angptl4 has also been shown to be required for dexamethasone-induced hepatic ceramide production. Here, we further examined the role of ceramide-mediated signaling in hepatic dyslipidemia caused by chronic glucocorticoid exposure. Using a stable isotope-labeling technique, we found that dexamethasone treatment induced the rate of hepatic de novo lipogenesis and triglyceride synthesis. These dexamethasone responses were compromised in Angptl4-null mice (Angptl4-/-). Treating mice with myriocin, an inhibitor of the rate-controlling enzyme of de novo ceramide synthesis, serine palmitoyltransferase long-chain base subunit 1 (SPTLC1)/SPTLC2, decreased dexamethasone-induced plasma and liver triglyceride levels in WT but not Angptl4-/- mice. We noted similar results in mice infected with adeno-associated virus-expressing small hairpin RNAs targeting Sptlc2. Protein phosphatase 2 phosphatase activator (PP2A) and protein kinase Cζ (PKCζ) are two known downstream effectors of ceramides. We found here that mice treated with an inhibitor of PKCζ, 2-acetyl-1,3-cyclopentanedione (ACPD), had lower levels of dexamethasone-induced triglyceride accumulation in plasma and liver. However, small hairpin RNA-mediated targeting of the catalytic PP2A subunit (Ppp2ca) had no effect on dexamethasone responses on plasma and liver triglyceride levels. Overall, our results indicate that chronic dexamethasone treatment induces an ANGPTL4-ceramide-PKCζ axis that activates hepatic de novo lipogenesis and triglyceride synthesis, resulting in lipid disorders
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Spring School on Language, Music, and Cognition: Organizing Events in Time
The interdisciplinary spring school “Language, music, and cognition: Organizing events in time” was held from February 26 to March 2, 2018 at the Institute of Musicology of the University of Cologne. Language, speech, and music as events in time were explored from different perspectives including evolutionary biology, social cognition, developmental psychology, cognitive neuroscience of speech, language, and communication, as well as computational and biological approaches to language and music. There were 10 lectures, 4 workshops, and 1 student poster session.
Overall, the spring school investigated language and music as neurocognitive systems and focused on a mechanistic approach exploring the neural substrates underlying musical, linguistic, social, and emotional processes and behaviors. In particular, researchers approached questions concerning cognitive processes, computational procedures, and neural mechanisms underlying the temporal organization of language and music, mainly from two perspectives: one was concerned with syntax or structural representations of language and music as neurocognitive systems (i.e., an intrapersonal perspective), while the other emphasized social interaction and emotions in their communicative function (i.e., an interpersonal perspective). The spring school not only acted as a platform for knowledge transfer and exchange but also generated a number of important research questions as challenges for future investigations
Direct Measurement of the System-Environment Coupling as a Tool For Understanding Decoherence and Dynamical Decoupling
Decoherence is a major obstacle to any practical implementation of quantum
information processing. One of the leading strategies to reduce decoherence is
dynamical decoupling --- the use of an external field to average out the effect
of the environment. The decoherence rate under any control field can be
calculated if the spectrum of the coupling to the environment is known. We
present a direct measurement of the bath coupling spectrum in an ensemble of
optically trapped ultracold atoms, by applying a spectrally narrow-band control
field. The measured spectrum follows a Lorentzian shape at low frequencies, but
exhibits non-monotonic features at higher frequencies due to the oscillatory
motion of the atoms in the trap. These features agree with our analytical
models and numerical Monte-Carlo simulations of the collisional bath. From the
inferred bath-coupling spectrum, we predict the performance of well-known
dynamical decoupling sequences: CPMG, UDD and CDD. We then apply these
sequences in experiment and compare the results to predictions, finding good
agreement in the weak-coupling limit. Thus, our work establishes experimentally
the validity of the overlap integral formalism, and is an important step
towards the implementation of an optimal dynamical decoupling sequence for a
given measured bath spectrum.Comment: 9 pages, 6 figure
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