21 research outputs found
FINE ADJUSTMENT OF THYROXINE REPLACEMENT DOSAGE: COMPARISON OF THE THYROTROPHIN RELEASING HORMONE TEST USING A SENSITIVE THYROTROPHIN ASSAY WITH MEASUREMENT OF FREE THYROID HORMONES AND CLINICAL ASSESSMENT
Effects of evening vs morning thyroxine ingestion on serum thyroid hormone profiles in hypothyroid patients
Shallow seismic stratigraphy and pockmarks of a hydrothermally influenced lake, Lake Rotoiti, New Zealand
Empty sella developing during thyroxine therapy in a patient with primary hypothyroidism and hyperprolactinaemia.
A 35 year old woman presented with severe primary hypothyroidism and galactorrhea. A very high prolactin level was also detected and computerized tomography scan of the sellar region demonstrated an enlarged pituitary gland associated with contrast enhancement. Replacement therapy with thyroxine corrected both biochemical and clinical abnormalities but empty sella developed during this therapy. It is concluded that empty sella may be related to thyroxine-induced shrinkage of lactotroph and/or thyrotroph cell hyperplasia