KORELASI KUNJUNGAN ANTENATAL CARE BURUH PABRIK DENGAN HASIL LUARAN BAYI DI KABUPATEN KUDUS

Latar Belakang : Hasil luaran bayi merupakan hasil dari kehamilan yang dapat berupa hasil luaran menguntungkan dan tidak menguntungkan. Kunjungan Antenatal care (ANC) yang adekuat dan berkualitas dipercaya dapat mencegah terjadinya hasil luaran yang tidak menguntungkan.Tujuan : penelitian ini adalah untuk menganalisis kunjungan ANC  buruh pabrik dengan hasil luaran bayi yang tidak menguntungkan. Penelitian ini dilakukan di Kabupaten Kudus dari bulan Februari-April 2013 dengan rancangan penelitian potong lintang dan didapatkan 92 responden.Metode :Analisis dilakukan secara bivariabel dengan menggunakan uji Rank Spearman,Hasil penelitian : menunjukkan ada korelasi antara kunjungan ANC dengan hasil luaran bayi, untuk jumlah kunjungan (r=0,206., p=0,049) dan waktu kunjungan (r=-0,455., p=0,000).Simpulan : dalam penelitian ini adalah jumlah dan waktu kunjungan ANC berkorelasi dengan hasil luaran bayi, semakin banyak jumlah kunjungan ANC semakin baik hasil luaran bayi dan semakin terlambat waktu kunjungan ANC semakin jelek hasil luaran bayi

KORELASI KEPEMIMPINAN DENGAN KOMITMEN DAN LINGKUNGAN KERJA DOSEN BERDASARKAN KRITERIA MALCOLM BALDRIGE (Suatu Survei Eksplanatori Pada Dosen Program Studi D3 Kebidanan di Propinsi Daerah Istimewa Yogyakarta)

Leadership in the field of midwifery diploma 3 hopefully can bring to positive change, the increase of organization quality which is a place of midwife graduates will exist in society. Leadership factor will facilitate to build high work commitment and good work environment. Malcolm Baldrige criteria is a work management system that can measure leadership, work commitment and work environment. This study aims to analyze correlation between leadership with work commitment and environment based on Malcolm Baldrige Criteria. Research design using analytic correlative study with explanatory survey. This study is quantitative research with crosssectional study. Subject of this study is 60 lecturers of diploma 3 midwifery in Province DIY. The research was conducted in March-April 2011 using questionnaire based on Malcolm Baldrige Criteria. Data reasearch was analized by Rank Spearman and Chi Square with level of significant based on p valu

Gambaran Rasionalitas Penggunaan Antibiotik berdasarkan Kriteria Gyssens di Bangsal Obstetri dan Ginekologi RSUP Dr. Hasan Sadikin Bandung

AbstrakTujuan: Penggunaan antibiotik yang tidak rasional terjadi di banyak rumah sakit dan dikaitkan dengan peningkatan jumlah resistensi antibiotik di seluruh dunia. WHO telah menggambarkan bahwa saat ini sedang terjadi “krisis” resistensi antibiotik yang berpotensi menyebabkan musibah secara global. Di Indonesia termasuk RSUP Dr. Hasan Sadikin Bandung data penelitian yang menggambarkan kualitas penggunaan antibiotik masih terbatas.Metode: Penelitian ini merupakan jenis penelitian deskriptif eksploratif dengan desain cross sectional dilaksanakan di RSUP Dr. Hasan Sadikin Bandung pada periode September–November 2016  pada pasien rawat inap di bangsal Obstetri dan Ginekologi. Rasionalitas penggunaan antibiotik diukur berdasarkan kriteria Gyssens yang  mengklasifikasikan kasus penggunaan antibiotik berdasarkan suatu alur memuat indikasi, jenis antibiotik, dosis, rute, interval, dan waktu pemberiannya.Hasil: Dari 150 kasus mayoritas merupakan kasus obstetri (62,7%) dengan kelompok umur terbanyak antara 21−35 tahun (73,3%). Berdasarkan  kriteria gyssens didapatkan terbanyak adalah kategori V (40,3%), sedangkan kategori 0 (antibiotik rasional) didapatkan sebanyak (22%).Kesimpulan: Penggunaan antibiotik yang tidak rasional berdasarkan kriteria Gyssens masih tinggi ditemukan di bangsal Kandungan dan KebidananThe Rationality of Antibiotic use based on Gyssens Criteria at Obstetric and Gynecology Ward Dr. Hasan Sadikin General HospitalAbstractObjective: The use of irrational antibiotics occurs in many hospitals and is associated with an increase of antibiotic resistance worldwide. WHO has described that there is currently a “crisis” of antibiotic resistance that has the potential to cause a global disaster. In Indonesia, including dr. Hasan Sadikin Hospital research data describing the quality of antibiotic use is still limited.Method: This study is a descriptive explorative research with cross sectional design that was conducted in dr. Hasan Sadikin Hospital on September until November 2016 with the sample was all inpatient that trated in the Obstetric and Gynecology ward.. The rationality of antibiotic use is measured by the Gyssens criteria that classify cases of antibiotic use based on a path containing indications, type of antibiotics, doses, routes, intervals, and time of administration.Result: Of the 150 cases the majority were obstetric cases (62.7%) with the most age group between 21-35 years (73.3%). Based on the criteria gyssens obtained the most is category V (40.3%), while category 0 (rational antibiotics) obtained as much (22%).Conclusion: The use of irrational antibiotics based on the Gyssens criterion is still high in the Obstetric and Gynecology wardKey words: Antibiotics, quality of antibiotic use, criteria gyssen

Soluble Endoglin Serum Level is Higher in Preeclampsia Compared to Molar and Normal Pregnancy

Abstract Objective: To analyze th e differences of maternal serum soluble endoglin level in pr eeclampsia, molar pregnan cy, and normal pregnancy, and to analyze th e correlation between maternal serum soluble endoglin level with gestational age. Method: This is a cros s-sectional compara tive analytic study involving 18 preeclamps ia cases, 18 molar pr egnan cies, and 18 normal pregnancies. The sample were obtained from Dr. Hasan Sad ikin hospital and six satellite hospitals from January until Mar ch 2013. The comparison of mean seng se rum level of th e preeclampsia,molar pregnancy, and normal pregnancy gro up was calculated using Kruskal Wallis, and the corr elation we re calculated using Rank Spearman. Result: The mean level of seng se rum in pr eeclamp sia gro up was higher (168.79 ngjml) than in molar pr egnan cy (43.47 ngjml) and normal pregnancy (32.38 ngjml). Ther e is no significant difference of se rum seng level be tween molar and norm al pregnan cy, with p value of 0.393 (p>0.05). There is significant differ ences of seng serum level between pr eeclampsia gro up and molar pr egnancy (p=O.OOO), but no significant differ ences between molar and normal pregnancy, p value=0.393 (p >0.05). Ther e is positive correlati on between seng se rum level of norm al pregnancy with gestational age (rs=0 .647 ; p<0.001). Conclusion: Mat ern al se rum seng level in preeclampsia is higher than th e level of which in molar pre gnan cy and norm al pregnancy. Keywords: molar pregnancy, norm al pr egnancy, pr eeclamp sia, soluble endoglin leve

PENGARUH KUALITAS IMPLEMENTASI KURIKULUM PRAKTIK PADA KEPUASAN LULUSAN DAN DAMPAKNYA PADA KINERJA BIDAN

Latar Belakang: Kualitas implementasi kurikulum praktik meliputi dimensi kehandalan, daya tanggap,  jaminan, empati, dan penampilan fisik merupakan  salah  satu alat pemasaran  jasa yang utama untuk mencapai tujuan organisasi, sekaligus memuaskan kebutuhan dan keinginan pelanggan dalam hal  ini adalah  lulusan dan pengguna  lulusan. Tujuan penelitian  ini untuk mengetahui pengaruh kualitas implementasi kurikulum praktik yang meliputi dimensi kehandalan, daya tanggap, jaminan, empati, dan tampilan fisik terhadap kepuasan lulusan dan mengetahui dimensi mana  yang pengaruhnya paling besar  terhadap kepuasan  lulusan D  III Kebidanan Poltekkes Kemenkes Tanjungkarang di Kota Bandar Lampung. Penelitian deskriptif analitik dengan pendekatan cross  sectional serta menggunakan  teknik acak  sederhana proporsional, telah dilakukan terhadap 50 bidan lulusan tahun 2009 dan 2010 yang memenuhi kriteria inklusi dan eksklusi. Variabel kualitas  implementasi kurikulum praktik dan kepuasan  lulusan diukur dengan menggunakan kuesioner dengan skala Likert 1-5. Uji statistik dengan diagram kartesius Importance performance, Pearson Product Moment dan analisis  jalur (path analysis). Hasil penelitian ini mencatat bahwa pengaruh kualitas implementasi kurikulum terhadap kepuasan lulusan secara simultan adalah 83% (nilai p ≤ 0,05). Secara parsial dimensi yang mempunyai pengaruh  bermakna  terhadap  kepuasan  lulusan  adalah  dimansi daya  tanggap,  empati  dan penampilan fisik (nilai p ≤ 0,05). Pengaruh daya tanggap, empati dan penampilan fisik masing-masing adalah 33,4%, 18,8%, dan 29,7% sehingga total pengaruh gabungan adalah 82% (nilai p ≤ 0,05). Simpulan: bahwa  kualitas  implementasi  kurikulum  praktik  berpengaruh  secara simultan terhadap kepuasan lulusan dan dimensi yang paling berpengaruh adalah daya tanggap dan penampilan fisik. Perlu diteliti faktor-faktor lain yang berkaitan dengan kepuasan lulusan dan pengguna lulusan. Kata kunci: jasa pendidikan, kualitas implementasi kurikulum praktik, lulusan

Comparative Preliminary Analysis of Umbilical Cord Blood-, Healthy Adult Peripheral Blood- and Myocardial Infarct Peripheral Blood-Derived Endothelial Progenitor Cells

BACKGROUND: Cardiovascular disease is a leading cause of death globally with the 287,000 deaths per years, characterized by declining of heart function caused by the reduction of heart capacity and lead to heart failure. Cell therapy using endothelial progenitor cells (EPCs) has a big potential for cardiovascular regeneration. EPCs are cells that have ability to differentiate into endothelial cells that can be mobilized and integrated into the defected blood vessel by angiogenesis. AIM: We aimed to seek the superior EPCs derived from MNCs for functional improvement of advanced heart failure patient by cell therapy using EPCs. MATERIALS AND METHODS: We did preliminary analysis to compare umbilical cord blood (UCB), healthy adult peripheral blood (PB)-, and myocardial infarct PB-derived EPCs characteristic and surface phenotypes. Different sources of each EPCs mononuclear cells were characterized by the expression of endothelial (cluster of differentiation [CD] 31, acethylated low-density lipoprotein, and von Willebrand) and hematopoietic stem cell (CD45, CD34, and CD133) surface markers with flow cytometry. RESULTS: In this study, EPCs and the conditioned medium (CM) have been produced and characterized in laboratory scale by comparing several sources of EPCs for instance UCB, PB from healthy people, and patients with myocardial infarction. We have shown that EPC characterizations from each group were not significantly different, but vascular endothelial growth factor and hepatocyte growth factor in UBC-derived CM-EPCs were higher than in PB. CONCLUSION: In conclusion, the UBC-derived EPCs might have a better potential for cardiovascular regeneration

Mobile Phone Text Messaging Cross Platform Intervention for Cervical Cancer Screening: Changes in Knowledge and Attitude in Rural Areas Pre-Post Intervention

The key to the success of cervical cancer control programs is screening followed by adequate treatment. The socio-economic status gap and the low level of education lead to limited awareness and understanding of women of childbearing age. Increasing the capacity of knowledge of women of childbearing age through health education either directly or indirectly is important. Therefore, there is need to develop health education by utilizing the rapidly growing media today such as through the application of cross platform messages on smartphones. This study aims to analyze the effect of the application of health education on detection of cervical cancer through the application of cross-platform messages to increase knowledge and attitude of Women in Childbearing Age. A quasi-experimental research of pre-posttest design with control groups conducted consisting of 72 subjects of Women in Childbearing Age. Fogg's Behavior Model was the conceptual framework that guided the development of the cross-platform messaging intervention. A series of checklist from expert panel conducted to inform the development of the cross-platform messaging intervention. The messages are delivered for a 7-day period in the morning. Data collection using a checklist instrument. Univariable analysis through Rasch and bivariable modeling using numerical categorical comparative test, difference using T test. Findings revealed a significant increase in participants’ knowledge and attitude of cervical cancer screening. Women of Childbearing Age whose health education through cross-platform application has a 3.5 times probability of knowledge and good attitude compared to women of childbearing age who are not getting health education through cross-platform applications. Health education through cross-platform messaging services can be a cheap and effective method to improve the knowledge and attitude of women of childbearing age, as well as reaching individuals who have never done early detection of cervical cancer

Hubungan Antara Kadar Protein BCL-2 Dan Caspase 3 Sebagai Faktor Risiko Pada Kejadian Abortus

Untuk mengetahui korelasi antara kadar protein Bcl-2 dan caspase-3 pada kehamilan normal dan abortus, serta kekuatan kadar protein Bcl-2 dengan caspase-3 sebagai alat ukur untuk uji diagnostik. Penelitian analitik dengan menggunakan rancangan case control terhadap 38 subjek dengan abortus dan 38 subjek dengan kehamilan normal sebagai kontrol yang memenuhi kriteria inklusi. Untuk melihat keeratan hubungan antara kadar protein Bcl-2 dan caspase-3 dilakukan analisis dengan uji korelasi Pearson, sedangkan untuk uji diagnostik digunakan kurva ROC (Receiver Operating Characteristics). Rerata kadar Bcl-2 pada subjek dengan abortus lebih rendah yaitu 7,263 (SB 1,71) ng/mL, sedangkan kehamilan normal 7,490 (SB 3,938) ng/mL (p=0,050). Rerata kadar caspase-3 pada subjek abortus lebih tinggi yaitu 112,74 (SB 152,73) mg/mL, sedangkan kehamilan normal 14,94 (SB 23,18) mg/mL (p&lt;0,001). Tidak terdapat korelasi bermakna antara kadar protein Bcl-2 dan caspase-3 pada kehamilan normal dan abortus walaupun terlihat kecenderungan semakin meningkat kadar protein Bcl-2 semakin tinggi kadar caspase-3 (r=0,093). Bcl-2 mempunyai cut-off point &gt;6,49 mg/mL (OR=3,58) dan caspase-3 mempunyai cut-off point &gt;11,25 ng/mL (OR=28,63). Tidak terdapat korelasi bermakna antara kadar protein Bcl-2 dan caspase-3 pada kasus abortus (r=0,093). Bcl-2 (cut-off point &gt;6,49 ng/mL) mempunyai kecenderungan abortus 3,58 kali dan caspase-3 (cut-off point &gt;11,25mg/mL) mempunyai kecenderungan abortus 28,63 kali