135 research outputs found

    Modeling Virtual Reality Web Application

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    This chapter introduce Quest 3D, that is a perfect software package for creating interactive 3D scene including product presentation, architectural visualizations, virtual trainings and computer games. Quest 3D is a software for creating interactive 3D scene, in a unique style of programming. Instead of having to write thousands of lines of complex code, developers make use of a large set of a powerful building blocks. Both flexible and easy to use, Quest 3D appeals to designers, programmers and artist alike. Working with Quest 3D means developing in a real-time: you are working directly on the end result. No time will be lost on compiling code or rendering image. While the logic tree scanning goes on, system shows the visualization of scene in the window application. Quest 3D has a stunning set of graphics features. Large numbers of animated people, vegetation, shadows, fire and smoke effects and realistic water can all be easily added to a scene. Advanced features include physics simulation, path finding routines, database connectivity and networking support. By this way is possible design very simple scene like extremely complex projects: software product always will appear readable and smart

    New abelisaurid skeletal remains from La Invernada (Bajo de la Carpa Formation, Santonian), northwestern Patagonia, Argentina

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    The La invernada fossil area (Bajo de la Carpa Formation, Santonian) has provided abundant dinosaur remains, which are mainly represented by titanosauriform sauropods and abelisaurid theropods. The latter include Viavenator exxoni and other partial skeletons. Recently a new abelisaurid specimen (MAu-Pv-Li-665) was found in La invernada, which consists of three vertebrae (anterior cervical, cervico-dorsal and dorsal) and cervical and dorsal ribs, found closely associated.Fil: Gianechini, Federico Abel. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas. Área de Zoología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto Multidisciplinario de Investigaciones Biológicas de San Luis. Universidad Nacional de San Luis. Facultad de Ciencias Físico Matemáticas y Naturales. Instituto Multidisciplinario de Investigaciones Biológicas de San Luis; ArgentinaFil: Méndez, Ariel Hernán. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto Patagónico de Geología y Paleontología; ArgentinaFil: Filippi, Leonardo Sebastián. Gobierno de la Provincia del Neuquén. Municipalidad de Rincón de Los Sauces. Secretaria de Turismo y Patrimonio. Museo Municipal Argentino Urquiza; ArgentinaFil: Juarez Valieri, Ruben Dario. Gobierno de la Provincia de Río Negro. Ministerio de Turismo, Cultura y Deporte. Secretaría de Cultura; Argentina1º Reunión Virtual de Comunicaciones de la Asociación Paleontológica ArgentinaBuenos AiresArgentinaAsociación Paleontológica Argentin

    The Ability to Look Beyond. The Treatment of Peripheral Arterial Disease

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    This paper offers a practical overview of the contemporary management of patients with peripheral arterial disease presenting intermittent claudication (IC), including clinical and instrumental diagnosis, risk factors modification, medical management, and evidence-based revascularization indications and techniques. Decision making represents a crucial element in the management of the patient with IC; for this, we think a review of this type could be very useful, especially for non-vascular specialists

    Glucan particles loaded with a NIRF agent for imaging monocytes/macrophages recruitment in a mouse model of rheumatoid arthritis

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    Glucan Particles (GPs) are hollow pseudo-microspheres (average diameter 3?5 mm) obtained from common baker´s yeast Saccharomyces cerevisiae, in which mannan, lipids and proteins are removed through a process of chemical extraction. GPs shell is mostly made of 1,3-b-D-glucan that allows for their prompt in vivo uptake by immune system cells. In this work, the inner cavity of the particles has been loaded with two amphiphilic fluorescent dyes (based on cyanine for in vivo imaging purposes and rhodamine for ex vivo microscopy experiments) through a sudden change in solvent polarity that allowed the entrapment of the molecules as microemulsion. The ability of fluorescent GPs to label immune cells in vivo and report on their recruitment in inflamed sites has been successfully demonstrated in a mouse model of rheumatoid arthritis (CIA) by NIRF imaging. Besides providing the visualization of the mononuclear cell infiltration in the lesion, the fluorescent signal well correlated with the clinical score associated with the disease. Very interestingly, the signal detected in lesions with the same clinical score allowed the assessment of the time evolution (progression or remission) of the pathology.Fil: Garello, Francesca. Universitã â  Di Torino; ItaliaFil: Arena, Francesca. Universitã â  Di Torino; ItaliaFil: Cutrin, Juan Carlos. Universitã â  Di Torino; Italia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Cardiológicas (i); ArgentinaFil: Esposito, Giovanna. Universita di Torino; ItaliaFil: D'angeli, Luca. University Of London; Reino UnidoFil: Cesano, Federico. Universita di Torino; ItaliaFil: Filippi, Miriam. Universitã â  Di Torino; ItaliaFil: Figueiredo, Sara. Universitã â  Di Torino; Italia. Universidad de Coimbra; PortugalFil: Terreno, Enzo. Universita di Torino; Itali

    The current deglaciation of the Ortles-Cevedale massif (Eastern Italian Alps): impacts, controls and degree of imbalance.

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    The Ortles-Cevedale is the largest glacierized mountain group of the Italian Alps hosting 112 ice bodies, with a total area of 76.8 km2. Since the 1980\u2019s, this massif is undergoing a rapid deglaciation, as most of the mountain ranges in the European Alps. The aims of this work were: i) to quantify area and volume change of the Ortles- Cevedale glacier system from the 1980s to the 2000s; ii) to improve the knowledge of factors controlling the spatial variability of the deglaciation; and iii) to assess the degree of imbalance of individual glaciers with respect to the present climate conditions. Two inventories were created, based on Landsat5 TM scenes of 20-09-1987 and 31-08-2009. Contrast-enhanced composites (bands TM5, TM4 and TM3), aerial photos and field surveys (for the most recent period) were used to correct the automatic delineation of glaciers derived from a hard classification based on a threshold applied to a TM3/TM5 ratio image. Since Landsat scenes were acquired at the end of the ablation seasons and fresh snow was absent, the accumulation areas could be roughly determined by mapping the snow covered area. This region was identified from the difference in reflectance between snow and ice in the near infrared band of Landsat (TM4), and mapped after correcting topographic effects to determine surface reflectance. The area-averaged geodetic mass budget was then calculated for the individual glaciers by differencing two Digital Terrain Models (2000s minus 1980s, derived from LiDAR and aerial photogrammetry) and combining the result with the glacier outlines. Afterwards, we examined the mass balance data using statistical analyses (Correlation matrices, Principal Component Analysis, Cluster Analysis). This allowed us highlighting clusters of glaciers, which exhibit a similar behavior, identify the outlayers and the relative influence of the factors controlling spatial variability of the mass losses. Finally, we assessed the degree of imbalance of individual glaciers by comparing the current Accumulation Area Ratios (AAR) with the balanced-budget AAR (AAR0), the latter also accounting for the debris cover of glaciers. We found that the total area loss of the Ortles-Cevedale glaciers from 1987 to 2009 amounts to 23.5 km2, i.e. 23.4% of the initial area. On the other hand, the AAR of the entire glacier system was 0.3 in both investigated years. The overall debris cover increased from 10.5% to 16.3%. The geodetic mass balance rate was -0.7 m w.e. y1(as an average on 112 ice bodies), ranging from -0.1 to -1.7 m w.e. y1. We also found that the main controls of the differing change of single glaciers are related to their hypsometry (elevation range and slope), AAR, feeding source and debris cover. Interestingly, a significant correlation was found between AAR, AAR0 and debris cover. This information was used to assess and visualize the needed additional reduction of individual glaciers to reach equilibrium with the current size of their accumulation areas. This amounts on average to a further reduction of 40% of the current areal extent of glaciers

    Lymphogranuloma venereum proctitis mimicking inflammatory bowel diseases in 11 patients: a 4-year single-center experience

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    ABSTRACT Lymphogranuloma venereum (LGV) is a sexually transmitted disease caused by Chlamydia trachomatis (CT) serovars L1–L3. Our study wants to underline the similarities between rectal LGV and idiopathic inflammatory bowel diseases (IBD), which can share clinical, endoscopic and histopathological findings

    Morphofunctional characterization of a rare extracranial internal carotid artery giant aneurism

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    Aneurisms of the extracranial tract of the internal carotid artery (EICAA) are extremely rare, accounting for 0,4% to 2% of all carotid procedures (El-Sabrout et al., 2000); in females incidence is 2-11 times lower than in males (Siablis et al., 2004). A giant EICAA (32 x 35 mm) at C3 level was studied in a woman aged 81. Samples were prepared for standard transmission electron microscopy. Semithin sections were stained according to Relucenti et al. (2010). Ultrathin sections were contrasted with uranyl acetate and lead citrate. Images revealed the presence of many microvessels just beneath the tunica intima. They were patent, often showed sprouts and pericytes. Endothelial cells appeared metabolically active, with euchromatin, nucleoli, membrane blebs and junctional complexes. Their basal membrane was thickened and sometimes multilaminated. Leukocytes adhering to the endothelium were observed. The internal elastic lamina was so fragmented that it was very difficult to recognize it. The tunica media showed vascular smooth muscle cells (VSMCs) arranged in bundles encircled by collagen-rich extracellular matrix (EM), as well as scattered in the EM. VSMCs had perinuclear organelles, dense bands and caveolae. Collagen fibrils were arranged in a twisted or coiled fashion. Elongated fibroblasts were scattered among VSMCs. The external elastic lamina was conserved. Literature on EICAA is almost exclusively clinical, so this morphofunctional study elucidates structural and ultrastructural changes in the aneurism wall that can contribute to the knowledge of aneurism etiopathogenesis
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