415 research outputs found

    Métodos, técnicas y estrategias para mejorar la seguridad de los sistemas de software

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    Con el crecimiento de internet y las distintas dinámicas de la sociedad actual; ha cambiado en gran medida la forma de interactuar e intercambiar información entre las personas y las empresas. Este intercambio se vuelve blanco de ataques por parte de todos aquellos actores que quieren obtener información útil y valiosa a sus propios intereses o de terceros. Ante este panorama se vuelve imperioso implementar todo tipo de medidas y acciones tendientes a evitar estos ataques, por tal motivo nace lo que se denomina Seguridad Informática. Toda acción, herramienta o metodología enfocada a evitar, contrarrestar o retrasar ataques contra activos sensibles juega un rol sumamente importante para los diversos actores. Por lo antes descrito, en este artículo se presenta una línea de investigación que aborda el diseño y construcción de una herramienta cuyo principal objetivo es desarrollar e incrementar el nivel de seguridad de Servicios Web.Eje: Seguridad Informática.Red de Universidades con Carreras en Informátic

    ATENOS: un programa para mejorar la seguridad en WSDL

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    Con el crecimiento de internet y las distintas dinámicas de la sociedad actual, ha cambiado en gran medida la forma de interactuar e intercambiar información entre las personas y las empresas. Este intercambio se vuelve blanco de ataques por parte de todos aquellos actores que quieren obtener información útil y valiosa a sus propios intereses o de terceros. Ante este panorama se vuelve imperioso implementar todo tipo de medidas y acciones tendientes a evitar estos ataques, por tal motivo nace lo que se denomina Seguridad Informática. Toda acción, herramienta o metodología enfocada a evitar, contrarrestar o retrasar ataques contra activos sensibles juega un rol sumamente importante para los diversos actores. Por lo antes explicado, se describe en este artículo una herramienta cuyo principal objetivo es desarrollar e incrementar el nivel de seguridad de Servicios Web.info:eu-repo/semantics/publishedVersio

    Métodos, técnicas y estrategias para mejorar la seguridad de los sistemas de software

    Get PDF
    Con el crecimiento de internet y las distintas dinámicas de la sociedad actual; ha cambiado en gran medida la forma de interactuar e intercambiar información entre las personas y las empresas. Este intercambio se vuelve blanco de ataques por parte de todos aquellos actores que quieren obtener información útil y valiosa a sus propios intereses o de terceros. Ante este panorama se vuelve imperioso implementar todo tipo de medidas y acciones tendientes a evitar estos ataques, por tal motivo nace lo que se denomina Seguridad Informática. Toda acción, herramienta o metodología enfocada a evitar, contrarrestar o retrasar ataques contra activos sensibles juega un rol sumamente importante para los diversos actores. Por lo antes descrito, en este artículo se presenta una línea de investigación que aborda el diseño y construcción de una herramienta cuyo principal objetivo es desarrollar e incrementar el nivel de seguridad de Servicios Web.Eje: Seguridad Informática.Red de Universidades con Carreras en Informátic

    Pharyngocutaneous fistula following total laryngectomy

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    Pharyngocutaneous fistula (PCF) is the most common complication after total laryngectomy. Objectives: To establish the incidence of this complication and to analyze the predisposing factors. Method: This is a cross-sectional study of a historical cohort including 94 patients who underwent total laryngectomy. The following aspects were correlated to the occurrence of PCF: gender, age, tumor site, TNM staging, type of neck dissection, previous radiation therapy, previous tracheotomy, and use of stapler for pharyngeal closure. The following were considered in PCF cases: the day into postoperative care when the fistula was diagnosed, duration of occurrence, and proposed treatment. Results: Twenty (21.3%) patients had PCF. The incidence of PCF was statistically higher in T4 tumors when compared to T2 and T3 neoplasms (p = 0.03). The other analyzed correlations were not statistically significant. However, 40.9% of the patients submitted to tracheostomy previously had fistulae, against 21.1% of the patients not submitted to this procedure. Conclusion: Advanced primary tumor staging is correlated with higher incidences of PCF

    Alternatives for the Management of Industrial Forest Waste: Energy, Bioethanol, and Cellulose Pulp

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    Modern kraft pulp mills generate solid waste of 1–2% of incoming debarked wood. Given the size of these plants, with an annual production capacity of at least 1000,000 tons, each plant generates 20,000–30,000 dry tons of waste per year. The largest current use of these residues is for combustion in biomass boilers for steam and power generation. However, the conversion of biomass into biofuels and chemicals is gaining interest due to increasing demands for energy, limited sources of fossil fuels, and growing concerns about the environmental impact of greenhouse gas emissions. This chapter shows the laboratory-scale results of the use of eucalyptus wood wastes to obtain cellulose pulp by alkali pulping reinforced with hydrogen peroxide to obtain alkaline peroxide mechanical pulp or cellulosic bioethanol. Based on the results, an industrial-scale techno-economic analysis of the processes is presented and compared with current alternatives for energy generation

    First Results of the 140^{140}Ce(n,γ)141^{141}Ce Cross-Section Measurement at n_TOF

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    An accurate measurement of the 140^{140}Ce(n,γ) energy-dependent cross-section was performed at the n_TOF facility at CERN. This cross-section is of great importance because it represents a bottleneck for the s-process nucleosynthesis and determines to a large extent the cerium abundance in stars. The measurement was motivated by the significant difference between the cerium abundance measured in globular clusters and the value predicted by theoretical stellar models. This discrepancy can be ascribed to an overestimation of the 140^{140}Ce capture cross-section due to a lack of accurate nuclear data. For this measurement, we used a sample of cerium oxide enriched in 140^{140}Ce to 99.4%. The experimental apparatus consisted of four deuterated benzene liquid scintillator detectors, which allowed us to overcome the difficulties present in the previous measurements, thanks to their very low neutron sensitivity. The accurate analysis of the p-wave resonances and the calculation of their average parameters are fundamental to improve the evaluation of the 140^{140}Ce Maxwellian-averaged cross-section

    First Results of the 140^{140}Ce(n,γ)141^{141}Ce Cross-Section Measurement at n_TOF

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    An accurate measurement of the 140^{140}Ce(n,γ) energy-dependent cross-section was performed at the n_TOF facility at CERN. This cross-section is of great importance because it represents a bottleneck for the s-process nucleosynthesis and determines to a large extent the cerium abundance in stars. The measurement was motivated by the significant difference between the cerium abundance measured in globular clusters and the value predicted by theoretical stellar models. This discrepancy can be ascribed to an overestimation of the 140^{140}Ce capture cross-section due to a lack of accurate nuclear data. For this measurement, we used a sample of cerium oxide enriched in 140^{140}Ce to 99.4%. The experimental apparatus consisted of four deuterated benzene liquid scintillator detectors, which allowed us to overcome the difficulties present in the previous measurements, thanks to their very low neutron sensitivity. The accurate analysis of the p-wave resonances and the calculation of their average parameters are fundamental to improve the evaluation of the 140^{140}Ce Maxwellian-averaged cross-section

    Insight from an Italian Delphi Consensus on EVAR feasibility outside the instruction for use: the SAFE EVAR Study

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    BACKGROUND: The SAfety and FEasibility of standard EVAR outside the instruction for use (SAFE-EVAR) Study was designed to define the attitude of Italian vascular surgeons towards the use of standard endovascular repair (EVAR) for infrarenal abdominal aortic aneurysm (AAA) outside the instruction for use (IFU) through a Delphi consensus endorsed by the Italian Society of Vascular and Endovascular Surgery (Societa Italiana di Chirurgia Vascolare ed Endovascolare - SICVE). METHODS: A questionnaire consisting of 26 statements was developed, validated by an 18 -member Advisory Board, and then sent to 600 Italian vascular surgeons. The Delphi process was structured in three subsequent rounds which took place between April and June 2023. In the first two rounds, respondents could indicate one of the following five degrees of agreement: 1) strongly agree; 2) partially agree; 3) neither agree nor disagree; 4) partially disagree; 5) strongly disagree; while in the third round only three different choices were proposed: 1) agree; 2) neither agree nor disagree; 3) disagree. We considered the consensus reached when >70% of respondents agreed on one of the options. After the conclusion of each round, a report describing the percentage distribution of the answers was sent to all the participants. RESULTS: Two -hundred -forty-four (40.6%) Italian Vascular Surgeons agreed to participate the first round of the Delphi Consensus; the second and the third rounds of the Delphi collected 230 responders (94.3% of the first -round responders). Four statements (15.4%) reached a consensus in the first rounds. Among the 22 remaining statements, one more consensus (3.8%) was achieved in the second round. Finally, seven more statements (26.9%) reached a consensus in the simplified last round. Globally, a consensus was reached for almost half of the proposed statements (46.1%). CONCLUSIONS: The relatively low consensus rate obtained in this Delphi seems to confirm the discrepancy between Guideline recommendations and daily clinical practice. The data collected could represent the source for a possible guidelines' revision and the proposal of specific Good Practice Points in all those aspects with only little evidence available

    Serum Albumin Is Inversely Associated With Portal Vein Thrombosis in Cirrhosis

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    We analyzed whether serum albumin is independently associated with portal vein thrombosis (PVT) in liver cirrhosis (LC) and if a biologic plausibility exists. This study was divided into three parts. In part 1 (retrospective analysis), 753 consecutive patients with LC with ultrasound-detected PVT were retrospectively analyzed. In part 2, 112 patients with LC and 56 matched controls were entered in the cross-sectional study. In part 3, 5 patients with cirrhosis were entered in the in vivo study and 4 healthy subjects (HSs) were entered in the in vitro study to explore if albumin may affect platelet activation by modulating oxidative stress. In the 753 patients with LC, the prevalence of PVT was 16.7%; logistic analysis showed that only age (odds ratio [OR], 1.024; P = 0.012) and serum albumin (OR, -0.422; P = 0.0001) significantly predicted patients with PVT. Analyzing the 112 patients with LC and controls, soluble clusters of differentiation (CD)40-ligand (P = 0.0238), soluble Nox2-derived peptide (sNox2-dp; P < 0.0001), and urinary excretion of isoprostanes (P = 0.0078) were higher in patients with LC. In LC, albumin was correlated with sCD4OL (Spearman's rank correlation coefficient [r(s)], -0.33; P < 0.001), sNox2-dp (r(s), -0.57; P < 0.0001), and urinary excretion of isoprostanes (r(s), -0.48; P < 0.0001) levels. The in vivo study showed a progressive decrease in platelet aggregation, sNox2-dp, and urinary 8-iso prostaglandin F2 alpha-III formation 2 hours and 3 days after albumin infusion. Finally, platelet aggregation, sNox2-dp, and isoprostane formation significantly decreased in platelets from HSs incubated with scalar concentrations of albumin. Conclusion: Low serum albumin in LC is associated with PVT, suggesting that albumin could be a modulator of the hemostatic system through interference with mechanisms regulating platelet activation

    The risk of stroke recurrence in patients with atrial fibrillation and reduced ejection fraction

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    Abstract Background: Atrial fibrillation (AF) and congestive heart failure often coexist due to their shared risk factors leading to potential worse outcome, particularly cerebrovascular events. The aims of this study were to calculate the rates of ischemic and severe bleeding events in ischemic stroke patients having both AF and reduced ejection fraction (rEF) (⩽40%), compared to ischemic stroke patients with AF but without rEF. Methods: We performed a retrospective analysis that drew data from prospective studies. The primary outcome was the composite of either ischemic (stroke or systemic embolism), or hemorrhagic events (symptomatic intracranial bleeding and severe extracranial bleeding). Results: The cohort for this analysis comprised 3477 patients with ischemic stroke and AF, of which, 643 (18.3%) had also rEF. After a mean follow-up of 7.5 ± 9.1 months, 375 (10.8%) patients had 382 recorded outcome events, for an annual rate of 18.0%. While the number of primary outcome events in patients with rEF was 86 (13.4%), compared to 289 (10.2%) for the patients without rEF; on multivariable analysis rEF was not associated with the primary outcome (OR 1.25; 95% CI 0.84–1.88). At the end of follow-up, 321 (49.9%) patients with rEF were deceased or disabled (mRS ⩾3), compared with 1145 (40.4%) of those without rEF; on multivariable analysis, rEF was correlated with mortality or disability (OR 1.35; 95% CI 1.03–1.77). Conclusions: In patients with ischemic stroke and AF, the presence of rEF was not associated with the composite outcome of ischemic or hemorrhagic events over short-term follow-up but was associated with increased mortality or disability
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