9,441 research outputs found

    Optical fibers to measure temperature vertical profile at sea

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    The paper is focus in the use the optical fiber to measure the temperature in various heigh at the same time to get a temperature vertical variation. The temperature measurements are puntual while the Bragg gratings located in the fiber.Peer Reviewe

    Gestió econòmica de l'Aeroport del Prat

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    El treball estudia i compara els diferents tipus de gestió aeroportuària a Espanya i a Europa. A més analitza aeroports europeus de similars característiques que el de Barcelona, per tal de extreure unes ensenyances, per posteriorment tractar-les d'aplicar a l'Aeroport del Prat

    Regulation of Ribosomal RNA Production by RNA Polymerase I: Does Elongation Come First?

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    Ribosomal RNA (rRNA) production represents the most active transcription in the cell. Synthesis of the large rRNA precursors (35–47S) can be achieved by up to 150 RNA polymerase I (Pol I) enzymes simultaneously transcribing each rRNA gene. In this paper, we present recent advances made in understanding the regulatory mechanisms that control elongation. Built-in Pol I elongation factors, such as Rpa34/Rpa49 in budding yeast and PAF53/CAST in humans, are instrumental to the extremely high rate of rRNA production per gene. rRNA elongation mechanisms are intrinsically linked to chromatin structure and to the higher-order organization of the rRNA genes (rDNA). Factors such as Hmo1 in yeast and UBF1 in humans are key players in rDNA chromatin structure in vivo. Finally, elongation factors known to regulate messengers RNA production by RNA polymerase II are also involved in rRNA production and work cooperatively with Rpa49 in vivo

    Comparative Analysis of Combinations of Dimension Reduction and Data Mining Techniques for Malware Detection

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    Many malware detectors utilize data mining techniques as primary tools for pattern recognition. As the number of new and evolving malware continues to rise, there is an increasing need for faster and more accurate detectors. However, for a given malware detector, detection speed and accuracy are usually inversely related. This study explores several configurations of classification combined with feature selection. An optimization function involving accuracy and processing time is used to evaluate each configuration. A real data set provided by Trend Micro Philippines is used for the study. Among 18 di↵erent configurations studied, it is shown that J4.8 without feature selection is best for cases where accuracy is extremely important. On the other hand, when time performance is more crucial, applying a Na¨ıve Bayes classifier on a reduced data set (using Gain Ratio Attribute Evaluation to select the top 35 features only) gives the best results

    Evaluating the repetitive mucus extraction effects on mucus biomarkers, mucous cells, and the skin-barrier status in a marine fish model

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    Among all the mucosal barriers, the skin and its surrounding mucus are possibly the main defensive tool against changes in the environment that can be harmful for fish. Due to the extraction of this mucus being less invasive, the study of its production and functions has attracted great interest in recent years. However, there are still many gaps concerning the sampling process as well as the possible alterations in skin integrity and mucus composition. In the current study, the effects of skin mucus extraction were determined by comparing the effects of a single extraction (single extraction group, SEG) with those of three successive extractions separated by 3 days (repetitive extractions group, REG). Intact skin histology without mucus extraction (oEG) and both plasma and skin mucus biomarkers and antibacterial capacities were also assessed. Regarding the skin histology and skin barrier properties, both the SEG and REG did not show differences in the intact skin. Interestingly, repetitive mucus extractions seemed to activate skin mucus turnover, significantly increasing the number of small-sized mucous cells (cell area 150 mu m(2)). Repetitive extractions significantly decreased the amounts of soluble protein and increased cortisol secretion. These metabolites remained unaltered in the plasma, indicating different responses in the plasma and mucus. Despite changes in the mucus biomarkers, antibacterial capacity against pathogenic bacteria (Pseudomonas anguilliseptica and Vibrio anguillarum) was maintained in both the plasma and mucus irrespective of the number of mucus extractions. Overall, the mucus sampling protocol had little effect on skin integrity and mucus antibacterial properties, only modifying the amounts of soluble protein exuded and stimulating mucous cell replacement. This protocol is a feasible and minimally invasive way of studying and monitoring fish health and welfare and can be used as an alternative or a complement to plasma analysis. This methodology can be transferred to farm culture conditions and be very useful for studying threatened species in order to preserve fish welfare.info:eu-repo/semantics/publishedVersio
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