27 research outputs found

    Vegetable moisturizing raw material from “Caatinga” Brazilian biome: safety and efficacy evaluations of O/W cosmetic emulsions containing Kalanchoe brasiliensis extract

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    The purpose of this study was to evaluate the safety of Kalanchoe brasiliensis extract, followed by the development of an oil in water emulsion containing the K. brasiliensis leaves extract and evaluating its clinical moisturizing efficacy. The formulations containing sodium acrylates/ Beheneth-25 methacrylate Crosspolymer (and) hydrogenated polydecene (and) lauryl glucoside and 0.5% of extract were prepared. The extract was considered as non-irritating through skin irritant tests. The stability testing was carried out in different conditions for 90 days. The skin hydration was measured by capacitance measurement and transepidermal water loss using biophysical techniques. The results indicate that the formulation containing 0.5% of extract increased the hydration of the stratum corneum up to 5 h after application on the forearm. The transepidermal water loss was reduced when compared to the untreated area and placebo area. Therefore, we can conclude that the increased skin hydration and protection of barrier function can be attributed to the K. brasiliensis extract. This research presents a new raw material from the Brazilian Caatinga biome and shows its possible application in the development of cosmetic products

    Conhecendo os impactos pulmonares ocasionados pelo uso de cigarros eletrônicos

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    O presente trabalho tem por objetivo a análise dos impactos pulmonares que são ocasionados pelo uso de cigarros eletrônicos. Este trabalho trata-se de uma revisão integrativa, sendo realizada a partir da busca dos seguintes Descritores em Ciências da Saúde (DeCS) na base de dados PubMed: electronic; cigarette; lung; impacts. Dos artigos encontrados, foram selecionados apenas artigos publicados nos anos de 2021 a 2023 até a data de 25/10/2023, sendo escolhidos 18 artigos, em que 10 foram excluídos após a análise de enquadramento ao tema, sendo apenas 8 analisados para a confecção deste estudo. O uso de E-cigarros está relacionado a diversas alterações pulmonares, sendo que em 2019, nos Estados Unidos, foi responsável pelo surto de doença pulmonar associada a cigarros eletrônicos, além disso é capaz de induzir alterações como síndrome respiratória aguda grave, alterações na função e composição do surfactante alterando a hematose, tosse, falta de ar e dentre outras alterações. Com isto, é essencial que se faça um apanhado das principais evidências científicas acerca deste tema para que todas estas problemáticas sejam evidenciadas.&nbsp

    Applications of platelet- and leukocyte-rich fibrin (L-PRF) in Oral and Maxillofacial Surgery

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    Introduction: Oral and maxillofacial surgery plays a crucial role in the reconstruction and restoration of facial structures, seeking to improve both aesthetics and function. The use of platelet-rich fibrin (L-PRF) represents a notable advance, accelerating healing and improving surgical outcomes. Materials and Methods: This review covers 710 studies from various electronic databases (PubMed, Scopus, Web of Science, Science Direct and Google Scholar). The aim is to thoroughly investigate the applications of platelet- and leukocyte-rich fibrin (L-PRF) in Oral and Maxillofacial Surgery and Traumatology. Results: The analysis reveals that L-PRF stands out as an effective autologous therapy in oral and maxillofacial surgery. Its application shows remarkable potential for accelerating the healing process, contributing significantly to the effectiveness of procedures. Discussion: L-PRF has emerged as an excellent choice in oral and maxillofacial surgery and traumatology, improving both the aesthetic and functional aspects of facial reconstructions. This highlights the relevance of this autologous therapy and its benefits in surgical practice. Conclusion: The applications of platelet and leukocyte-rich fibrin (L-PRF) in Oral and Maxillofacial Surgery and Traumatology are fundamental and promising. This advance represents not only a means of accelerating healing, but also a significant contribution to better aesthetic and functional results in surgical procedures in this area.Introduction: Oral and maxillofacial surgery plays a crucial role in the reconstruction and restoration of facial structures, seeking to improve both aesthetics and function. The use of platelet-rich fibrin (L-PRF) represents a notable advance, accelerating healing and improving surgical outcomes. Materials and Methods: This review covers 710 studies from various electronic databases (PubMed, Scopus, Web of Science, Science Direct and Google Scholar). The aim is to thoroughly investigate the applications of platelet- and leukocyte-rich fibrin (L-PRF) in Oral and Maxillofacial Surgery and Traumatology. Results: The analysis reveals that L-PRF stands out as an effective autologous therapy in oral and maxillofacial surgery. Its application shows remarkable potential for accelerating the healing process, contributing significantly to the effectiveness of procedures. Discussion: L-PRF has emerged as an excellent choice in oral and maxillofacial surgery and traumatology, improving both the aesthetic and functional aspects of facial reconstructions. This highlights the relevance of this autologous therapy and its benefits in surgical practice. Conclusion: The applications of platelet and leukocyte-rich fibrin (L-PRF) in Oral and Maxillofacial Surgery and Traumatology are fundamental and promising. This advance represents not only a means of accelerating healing, but also a significant contribution to better aesthetic and functional results in surgical procedures in this area

    Uso de telas pela população pediátrica e seus impactos oftalmológicos a curto e a longo prazo: uma revisão sistemática : Use of screens by the pediatric population and its short and long-term ophthalmological impacts: a systematic review

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    Ao se discorrer sobre a formação e formatação da nossa sociedade, pode-se notar que cada vez mais esta está permeada pela tecnologia e pelos sistemas integrativos, processo esse benéfico para comunicação, gestão e tomada de decisões para além de ser uma ferramenta de trabalho e entretenimento, porém, com a progressiva quantidade de horas que ficamos expostos a este tipo de tecnologia também podem acarretar prejuízos a acuidade visual dos usuários. Juntamente a isso, nota-se que as crianças estão tendo cada vez mais precocemente acesso os equipamentos eletrônicos e deixando de lado as brincadeiras, desta forma a partir de uma pesquisa qualitativa, feita a partir de um levantamento bibliográfico, pode-se dispor que esta busca compreender quais são os sintomas e efeitos do uso excessivo deste tipo de ferramenta e algumas formas de tratamento e profilaxia que podem ser dispostas sobre o tema, com enfoque na população pediátrica

    Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study

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    Background Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide.Methods A multimethods analysis was performed as part of the GlobalSurg 3 study-a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital.Findings Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3.85 [95% CI 2.58-5.75]; p<0.0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63.0% vs 82.7%; OR 0.35 [0.23-0.53]; p<0.0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer.Interpretation Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised

    A experiência de alunos de graduação e pós-graduação em enfermagem no programa de inclusão universitária

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    Dentre os benefícios oriundos do engajamento dos acadêmicos universitários em projetos de extensão, destaca-se o fortalecimento do papel social e da cidadania, com o aprimoramento de habilidades e competências aprendidas em sua trajetória acadêmica. Este trabalho tem como objetivo relatar as experiências vividas por alunos de graduação e de pós-graduação da Escola de Enfermagem de Ribeirão Preto como monitores de um projeto de extensão universitária denominado “Programa Universitário Por Um Dia”, criado em 2016 mediante parceria da Escola de Enfermagem de Ribeirão Preto da Universidade de São Paulo (EERP-USP) com as Pró-Reitorias de Graduação e de Cultura e Extensão Universitária da USP. Diante dos relatos obtidos, os universitários arrolados no Programa tiveram a oportunidade de fortalecer suas habilidades de falar em público, organizar suas apresentações, aprimorar o relacionamento interpessoal com outros alunos, exercitar a capacidade de resolução de problemas, treinar a didática e organização pessoal. Durante a pandemia do COVID-19, as atividades do programa continuaram de maneira remota, onde os monitores colocaram todos seus aprendizados em prática e necessitaram adaptar os conteúdos. Essas atividades e desafios contribuíram para a construção diária das responsabilidades e consolidação profissional dos universitários e futuros docentes. Um dos indicadores de sucesso deste programa foi o ingresso na EERP-USP de três alunos do ensino médio, que visitaram o programa, e se tornaram monitores. Palavras-chave: Ensino Superior; Inclusão Social; Extensão Universitária; Oratória; Educação Básica Reports of undergraduate and postgraduate students in nursing from a university inclusion program Abstract: Among the benefits arising from the engagement of university students in extension projects, the strengthening of the social role and citizenship stands out, with the improvement of skills and competencies learned in their academic trajectory. This paper aims to report the experiences of undergraduate and graduate students at the Ribeirão Preto College of Nursing as monitors of a university extension project called "University for a Day Program," created in 2016 through a partnership with the Ribeirão Preto College of Nursing at the University of São Paulo (EERP-USP) with the Dean of Undergraduate Studies and Culture and University Extension at USP. Based on the reports obtained, the university students enrolled in the Program had the opportunity to strengthen their public speaking skills, organize their presentations, improve their interpersonal relationships with other students, exercise their problem-solving skills, train didactics and personal organization. During the COVID-19 pandemic, the Program's activities continued remotely, where monitors put all their learning into practice and needed to adapt the contents. These activities and challenges contributed to the daily construction of responsibilities and professional consolidation of university students and future teachers. One of the success indicators of this Program was the entry into the EERP-USP of three high school students who visited the Program and became monitors. Keywords: Higher Education; Social Inclusion; University Extension; Public Speaking; Basic Educatio

    Vegetable moisturizing raw material from "Caatinga" Brazilian biome: safety and efficacy evaluations of O/W cosmetic emulsions containing Kalanchoe brasiliensis extract

    Get PDF
    The purpose of this study was to evaluate the safety of Kalanchoe brasiliensis extract, followed by the development of an oil in water emulsion containing the K. brasiliensis leaves extract and evaluating its clinical moisturizing efficacy. The formulations containing sodium acrylates/Beheneth-25 methacrylate Crosspolymer (and) hydrogenated polydecene (and) lauryl glucoside and 0.5% of extract were prepared. The extract was considered as non-irritating through skin irritant tests. The stability testing was carried out in different conditions for 90 days. The skin hydration was measured by capacitance measurement and transepidermal water loss using biophysical techniques. The results indicate that the formulation containing 0.5% of extract increased the hydration of the stratum corneum up to 5 h after application on the forearm. The transepidermal water loss was reduced when compared to the untreated area and placebo area. Therefore, we can conclude that the increased skin hydration and protection of barrier function can be attributed to the K. brasiliensis extract. This research presents a new raw material from the Brazilian Caatinga biome and shows its possible application in the development of cosmetic products
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