Relación entre la estructura financiera de una empresa y la influencia en su valoración. Revisión bibliográfica y análisis empírico

Treball Final de Màster Universitari en Gestió Financera i Comptabilitat Avançada. Codi: SRL031. Curs acadèmic: 2016/2017The objective of this work is to make a bibliographical review and empirical analysis about the relationship between the financial structure of a company and the influence on its valuation, going through Modigliani and Miller with its different propositions, the theory of the trade off, the theory of agency, free cash flow, financing with or without debt, the theory of financial hierarchy and dividend policy and arriving at a comparative conclusion between the different theories.El objetivo de este trabajo es realizar una revisión bibliográfica y un análisis empírico acerca de la relación entre la estructura financiera de una empresa y la influencia en su valoración, pasando por Modigliani y Miller con sus diferentes proposiciones, por la teoría del trade off, la teoría de agencia, el free cash flow, el financiamiento con o sin deuda, la teoría de la jerarquía financiera y la política de dividendos y llegando a una conclusión comparativa entre las diferentes teoría

Contribution of Xenopus model to a better understanding of cardiac outflow tract

Contribution of Xenopus model to a better understanding of cardiac outflow tract. A Torres-Prioris 1, SJ Smith 2, TJ Mohun 2, B Fernández 1, AC Durán 1. 1 Department of Animal Biology, Faculty of Science, and Biomedical Research Institute of Málaga (IBIMA), University of Málaga, Spain. 2 Developmental Biology Division, The Francis Crick Institute, Mill Hill Laboratory, London, UK. The morphology and morphogenesis of the cardiac outflow tract is a major topic in the study of the vertebrate circulatory system, especially regarding the pathologies affecting this region in humans. Recent studies have demonstrated that, in fish, the cardiac outflow tract consists of a myocardial conus arteriosus and a nonmyocardial bulbus arteriosus. Moreover, the bulbus arteriosus of fish has been considered homologous to the intrapericardial base of the aortic and pulmonary trunks of birds and mammals. Under this perspective, we have conducted a study on the outflow tract of Xenopus laevis, using histological, immunohistochemical and 3D reconstruction techniques. It has been assumed that the outflow tract of Xenopus, which is intercalated between the ventricle and the great arterial trunks, is of myocardial nature. At its luminal side, it contains two sets of valves between which the so-called spiral valve lies. Our results demonstrate that, together with a proximal myocardial segment, a distal, nonmyocardial, intrapericardial segment is also present in amphibians. We propose that this distal segment, from which the pulmocutaneous and systemic arteries arise, is homologous to the bulbus arteriosus of fish. Therefore, the bulbus arteriosus is an evolutionarily conserved structure, which has become the aortic and pulmonary roots of birds and mammals. Our findings contribute to strengthening Xenopus as a good model to better understand the outflow tract morphology and evolution, and as an emerging model for studying human congenital heart diseases. This work was supported by CGL2010-16417, BES-2011-046901, Estancias Breves para FPI (2012, 2013) and FEDER funds.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech. CGL2010-16417, BES-2011-046901, Estancias Breves para FPI (2012, 2013), FEDER funds

Estudio microtermométrico mediante platina calentadora-refrigeradora de las inclusiones fluidas atrapadas en minerales

Memoria ID12-0093. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2012-2013

Diseño y elaboración de material docente para la enseñanza de los Yacimientos Minerales en los Grados en Geología e Ingeniería Geológica a través de la plataforma virtual studium.

Memoria ID-065. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2013-2014

Diseño y elaboración de una guía de apoyo y consulta de los alumnos para las clases prácticas de microscopía en la materia de Mineralogía de los Grados en Geología e Ingeniería Geológica

Memoria ID-0064. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2015-2016

Diseño y aplicación de metodologías docentes innovadoras que fomenten el aprendizaje de los alumnos en la materia de Mineralogía de los Grados en Geología e Ingeniería Geológica

Memoria ID-003. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2018-2019

Aprendizaje activo y autoevaluación en la identificación microscópica de minerales en la materia de Mineralogía

Memoria ID-0002. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2017-2018

Diseño y elaboración de material docente para la enseñanza de la Mineralogía en los Grados en Geología e Ingeniería Geológica a través de la plataforma virtual studium

Memoria ID-0021. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2014-2015

DISTRIBUTION OF PIGMENT CELLS IN THE HEART OF THE RABBITFISH, CHIMAERA MONSTROSA (CONDRICHTHYES: HOLOCEPHALI)

El resumen aparece en el Program & Abstracts of the 10th International Congress of Vertebrate Morphology, Barcelona 2013. Anatomical Record, Volume 296, Special Feature — 1: P-076.The study of extracutaneous cells producing and storing melanin is of interest because it may provide valuable information about the presence of neural crest elements in internal organs and tissues. Here we report, for the first time, the presence and distribution of melanophores in the heart of a chondrichthyan species, the rabbitfish, Chimaera monstrosa. Pigment cells were found in all of 20 hearts examined. Pigment cells occur mainly in the cardiac outflow tract, which consists of two anatomical components, the proximal, myocardial conus arteriosus and the distal, non-myocardial bulbus arteriosus. A few groups of dark pigmented cells were found in the apex of the ventricle of one specimen and in the atrium of two specimens. In all instances, the melanophores were located in the subepicardial space, where they could be well recognized in both unstained and stained histological sections. The distribution and intensity of the pigmentation in the cardiac outflow tract varies markedly between individuals. In all cases, however, the pigmented area is larger on the dorsal than on the ventral surface. Dorsally, the size of the pigmented area ranges from a fringe that includes the bulbus and the distal part of the conus to the whole surface of the outflow tract. Ventrally, the pigmented area does not cover the entire conus arteriosus. The intensity of the pigmentation also varies widely; in general, it is highest at the distal portion of the conus. There is no relationship between the distribution and intensity of the pigmentation and the sex and age of the animals. The functional role of the pigmented cells is unknown. If the melanophores in the heart of C. monstrosa are indeed of neural crest origin, it would suggest a notable contribution of the neural crest cells to the cardiac outflow tract in holocephalans.Proyecto CGL2010-16417/BOS; Fondos FEDER BES-2011-04690

PIGMENTATION OF THE HEART IN THE BICHIR, POLYPTERUS SENEGALUS

El resumen aparece en el Program & Abstracts of the 10th International Congress of Vertebrate Morphology, Barcelona 2013. Anatomical Record, Volume 296, Special Feature — 1: P-078.The presence of melanin-containing cells in the heart has been documented in tetrapods, but not in fish. It has been even suggested that dark pigmented cells are exclusively associated with hearts having two atria and two ventricles. The aim here is to report the occurrence of pigment cells in the heart of the bichir, an extant representative of the polypteriformes, an ancient ray-finned fish lineage that split from the stem of the actinopterygians soon after their divergence from the sarcopterygians. The bichir heart is composed of sinus venosus, atrium, ventricle, conus arteriosus and bulbus arteriosus arranged sequentially within the pericardial cavity. Dendritic-shaped cells containing melanosomes were found in the five cardiac components of the 12 bichirs included in this study. Numerous melanophores were distributed regularly over the surface of all segments having myocardium in their walls, thus resulting in a marked pigmentation of the whole heart. The bulbus arteriosus, which in the bichir is reduced in size, showed an even more intense pigmentation. In all instances, the melanophores were localized in the subepicardial space. Pigment cells also occurred in the pericardium and ventral aorta. The functional role of melanocytes in the tetrapod heart remains obscure. Antiinflamatory activity, cytoprotection and effects on the viscoelastic properties of the cardiac tissue have been adduced as possible actions of such cells. The role of pigment cells in the bichir heart constitutes a new open question. Interestingly, however, the only cells that have been shown to form melanin-containing cells in the heart derive from the neural crest. If the melanophores of the bichir heart are indeed of neural crest origin, it would suggest a much more extensive contribution and persistence of elements from the neural crest in the primitive heart of jawed vertebrates as assumed so far in most papers devoted to vertebrate heart embryology.Proyecto CGL2010-16417/BOS; Fondos FEDER; Beca FPI ref. BES-2011-046901