Effects of dietary black cumin (Nigella sativa L.) oil on growth performance, hemato-biochemical and histopathology of cypermethrin-intoxicated Nile tilapia (Oreochromis niloticus)

This study was conducted to investigate the effects of dietary black cumin (Nigella sativa L.) oil on growth performance, hemato-biochemical, and histopathology of cypermethrin-intoxicated Nile tilapia. After determining the LC50 (96 h) value of cypermethrin, cypermethrin was added to the water at a ratio of 1:20 of this concentration, and the fish were fed for 42 days. To reduce the effects of cypermethrin, 1% black cumin oil was added to the fish feed as a potential protectant. Growth parameters, hematology, blood biochemistry, and histopathological changes of Nile tilapia were examined after the feeding period. In this study, the best growth was observed in the group fed with feed containing 1% black cumin oil, while the worst growth performance was observed in the group fed with water containing cypermethrin and without black cumin oil in the feed. As a result of the study, it was observed that black cumin oil added to the fish diet reduced the negative effects of water-borne cypermethrin on growth, hematology, blood biochemistry, and histopathological parameters of Nile tilapia

Laryngoscopic Examination During the COVID-19 Pandemic: Turkish Voice Speech and Swallowing Disorders Society and Turkish Professional Voice Society Recommendations

COVID-19 is highly transmissible and spreads rapidly in the population. This increases the occupational risk for health care workers. In otolaryngology clinic practice, patients with upper respiratory tract infection symptoms are common. Also, routine head and neck examinations such as oral cavity examination, nasal/nasopharyngeal examination, or video laryngostroboscopic evaluation are highly risky because of the aerosol formation. To emphasize this issue, two leading otolaryngology organizations in Turkey; 'Voice Speech and Swallowing Disorders Society', and 'Professional Voice Society' gathered a task force. This task force aimed to prepare a consensus report that would provide practical recommendations of the safety measurements during routine clinical care of laryngology patients. To fulfill this, universal aim, on the 2nd and 9th of May 2020, two web-based meetings were conducted by 20 expert physicians. This eighteen items list was prepared as an output

Histopathology changes in the rainbow trout (Onchorhyncus mykiss) consuming boric acid supplemented fish fodder

Objective: Even though boron (B), as a trace micronutrient, occurs in natural waters and organisms, its high concentration could cause harmful and even toxic for organisms. The aim of present study was to investigate the effects of boric acid (BA) added to feed (0.01%, 0.05%, 0.10%, and 0.20% of B in feed) on Rainbow Trout (Oncorhynchus mykiss) by histopathological methods and compared to the control feed as without B. Methodology: At the end of the feeding, after weighing the live weight of 9 rainbow trout from each group, tissue fragments were taken from the liver, gill, kidney, skeletal muscle, spleen and brains of fish, which systemic necropsies was done, and were fixed in 10 % buffered formalin solution. Results: Histopathological examinations revealed degenerative and necrotic changes in the liver, gill, kidney, skeletal muscle, spleen and brain. Hydropic and vacuolar degenerations in liver parenchyma, lamellar edema in the gills, hyaline accumulation in the kidneys, degenerations in the muscles, necrosis in the spleen and hyperemia in the brain were observed in all groups except control group. It was observed that the destruction of boric acid on fish increased depending on the amount of boron supplemented to the feed, and the most effect was in the group fed with 0.20 % boron supplemented feed. Conclusions: The findings aside from causing pathological changes in all organs in terms of histopathological findings of Boric Acid (BA), the most severe lesions were observed in the liver

Termal Welding Sistemi ile Tonsillektomi Sonrası Ağrı Değerlendirilmesi

Amaç: Prospektif olarak termal welding sistemi ve soğuk teknik diseksiyon ile tonsillektomi uygulanmış pediatrik olgularda postoperatif ağrının kar- şılaştırılması. Hastalar ve Yöntem: Bu çalışmaya prospektif olarak Ocak ve Şubat 2007’de kurumumuza bağlı KBB Kliniklerinde genel anestezi altında adenotonsillektomi uygulanmış 44 çocuk hasta dahil edilmiştir. Hastalar taburcu edilirken Wong Baker görsel ağrı değerlendirme skalası verilip 1 hafta boyunca her sabah uyanınca analjezik almadan önce ağrılarının şiddetini değerlendirmeleri istenmiştir. Bulgular: Termal welding sistemi (TWS) tonsillektomi grubunda cerrahi sü- resi ortalama 29,17 dakika, soğuk teknik (ST) tonsillektomi grubunda ise 45,95 dakika idi. Cerrahi süreleri kıyaslandığında iki grup arasında istatistiksel olarak anlamlı bir fark vardı. (p < 0.01). TWS grubunda kanama miktarı ortalama 19,5ml iken ST grubunda 123,9 ml idi. İstatistiksel olarak ST grubunda kanama miktarı anlamlı olarak daha fazla idi. (p < 0.01). TWS grubu ve ST grubu arasında ortalama ağrı skorları arasında istatistiksel olarak anlamlı bir fark gözlenmedi (P > 0.05). Sonuç: TWS pediatrik hasta grubunda klasik yönteme göre postoperatif ağrı bakımından anlamlı bir farklılık göstermemektedir. Ancak etkin, güvenilir, yeterli hemostaz sağlayan, cerrahi süreyi kısaltan bir yöntemdir

Hoarseness and laryngopharyngeal reflux: a cause and effect relationship or coincidence?

WOS: 000240396200010PubMed: 16816932The role of laryngopharyngeal reflux (LPR) on hoarseness is widely assumed and accepted. Few articles present objective information on the subject. One of the main problems in establishing a relationship is our lack of knowledge of what is normal. We compared patients with chronic hoarseness and healthy controls to establish three goals: (1) to demonstrate the presence of additional symptoms and signs of LPR in patients with hoarseness; (2) to find the prevalence of LPR by utilizing 24 h double-probe in patients with hoarseness and compare it with that of the control group; (3) to contribute data to establish prevalence of LPR in healthy population. Forty-three patients with hoarseness and 20 healthy volunteers were enrolled in the study. All the patients in the study group had hoarseness of more than 3 months duration. The subjects recieved videolaryngoscopic evaluation and 24 h double-probe pH monitoring, and the results were compared. In the study group, 27 patients (62.8%) out of 43 had LPR episodes, compared to 6 (30%) of 20 healthy volunteers. Mean number of LPR episodes recorded by the pharyngeal probe was 7.0 [standard deviation (SD): 8.8] in 24 h, and this was significantly higher than that of the healthy controls [0.9/24 h (SD: 1.9)] (P = 0.003). Mean number of LPR episodes of the study group in upright position was 5.8 (SD: 7,0) and in supine position was 1.2 (SD: 3.3). These numbers were also significantly higher from the controls (P = 0.005 and P = 0.014 respectively). The results of this study show that: (1) most common additional symptoms were heartburn and chronic throat clearing and most common finding is pachydermia; (2) LPR incidence in patients with chronic hoarseness is significantly higher than the LPR incidence in healthy controls; (3) LPR is present in healthy people. However, the severity of LPR seems to be the causative factor rather than its presence